Frédéric Aubrun

Summary

Country: France

Publications

  1. ncbi Randomised, placebo-controlled study of the postoperative analgesic effects of ketoprofen after spinal fusion surgery
    F Aubrun
    Department of Anaesthesiology and Critical Care, Centre Hospitalier Universitaire Pitie Salpetriere, Paris, France
    Acta Anaesthesiol Scand 44:934-9. 2000
  2. doi Predictive factors of severe postoperative pain in the postanesthesia care unit
    Frédéric Aubrun
    Department of Anesthesiology and Critical Care, Groupe Hospitalier Pitie Salpetriere, Assistance Publique Hopitaux de Paris, Université Pierre et Marie Curie Paris, France
    Anesth Analg 106:1535-41, table of contents. 2008
  3. ncbi Effect of a low-dose ketamine regimen on pain, mood, cognitive function and memory after major gynaecological surgery: a randomized, double-blind, placebo-controlled trial
    F Aubrun
    Universite Pierre et Marie Curie Paris 6, Assistance Publique Hopitaux de Paris AP HP, Groupe Hospitalier Pitie Salpetriere, Department of Anesthesiology and Critical Care, Paris, France
    Eur J Anaesthesiol 25:97-105. 2008
  4. ncbi Effects of a loading dose of morphine before i.v. morphine titration for postoperative pain relief: a randomized, double-blind, placebo-control study
    F Aubrun
    Department of Anaesthesiology and Critical Care, Centre Hospitalo Universitaire Pitie Salpetriere, Assistance Publique Hopitaux de Paris, Universite Pierre et Marie Curie, Paris 6 Paris, France
    Br J Anaesth 98:124-30. 2007
  5. ncbi Management of postoperative analgesia in elderly patients
    Frédéric Aubrun
    département d anesthésie réanimation chirurgicale, Universite Pierre et Marie Curie, Paris, France
    Reg Anesth Pain Med 30:363-79. 2005
  6. ncbi Sex- and age-related differences in morphine requirements for postoperative pain relief
    Frédéric Aubrun
    Department of Anesthesiology and Critical Care, Groupe Hospitalier Pitie Salpetriere, Assistance Publique Hopitaux de Paris, Universite Pierre et Marie Curie, France
    Anesthesiology 103:156-60. 2005
  7. ncbi A high initial VAS score and sedation after iv morphine titration are associated with the need for rescue analgesia
    Frédéric Aubrun
    département d anesthésie réanimation chirurgicale, CHU Pitie Salpetriere, 47 Boulevard de l Hopital, 75651 Paris Cedex 13, France
    Can J Anaesth 51:969-74. 2004
  8. ncbi [Intravenous morphine titration]
    F Aubrun
    département d anesthésie réanimation chirurgicale, Groupe Hospitalier Pitie Salpetriere, Assistance Publique Hopitaux de Paris, Universite Pierre et Marie Curie, 47 83, Boulevard de l Hopital, 75651 Paris 13, France
    Ann Fr Anesth Reanim 23:973-85. 2004
  9. ncbi Adjunctive analgesia with intravenous propacetamol does not reduce morphine-related adverse effects
    F Aubrun
    Department of Anaesthesiology and Critical Care, Groupe Hospitalier Pitie Salpetriere, Assistance Publique Hopitaux de Paris AP HP, Universite Pierre et Marie Curie, Paris, France
    Br J Anaesth 90:314-9. 2003
  10. ncbi Postoperative morphine consumption in the elderly patient
    Frédéric Aubrun
    Department of Orthopedic Surgery, Group Hospitalier Pitie Salpetriere, Assistance Publique Hopitaux de Paris, Universite Pierre et Marie Curie, Paris, France
    Anesthesiology 99:160-5. 2003

Collaborators

Detail Information

Publications19

  1. ncbi Randomised, placebo-controlled study of the postoperative analgesic effects of ketoprofen after spinal fusion surgery
    F Aubrun
    Department of Anaesthesiology and Critical Care, Centre Hospitalier Universitaire Pitie Salpetriere, Paris, France
    Acta Anaesthesiol Scand 44:934-9. 2000
    ..Thus, we performed a prospective, placebo-controlled study to assess the analgesic effects of ketoprofen in patients undergoing spinal fusion surgery and receiving propacetamol...
  2. doi Predictive factors of severe postoperative pain in the postanesthesia care unit
    Frédéric Aubrun
    Department of Anesthesiology and Critical Care, Groupe Hospitalier Pitie Salpetriere, Assistance Publique Hopitaux de Paris, Université Pierre et Marie Curie Paris, France
    Anesth Analg 106:1535-41, table of contents. 2008
    ..We analyzed prospectively the pre- and intraoperative predictive factors of severe postoperative pain defined as a dose of IMT >0.15 mg/kg or a failure of IMT...
  3. ncbi Effect of a low-dose ketamine regimen on pain, mood, cognitive function and memory after major gynaecological surgery: a randomized, double-blind, placebo-controlled trial
    F Aubrun
    Universite Pierre et Marie Curie Paris 6, Assistance Publique Hopitaux de Paris AP HP, Groupe Hospitalier Pitie Salpetriere, Department of Anesthesiology and Critical Care, Paris, France
    Eur J Anaesthesiol 25:97-105. 2008
    ..A low-dose ketamine regimen appears to prevent postoperative hyperalgesia. We examined the potential beneficial effect of ketamine on postoperative pain management and cognitive function...
  4. ncbi Effects of a loading dose of morphine before i.v. morphine titration for postoperative pain relief: a randomized, double-blind, placebo-control study
    F Aubrun
    Department of Anaesthesiology and Critical Care, Centre Hospitalo Universitaire Pitie Salpetriere, Assistance Publique Hopitaux de Paris, Universite Pierre et Marie Curie, Paris 6 Paris, France
    Br J Anaesth 98:124-30. 2007
    ..However, MT has limitations such as a delay to achieve pain relief. We thus assessed the effect of a fixed intraoperative loading dose of morphine administered before titration...
  5. ncbi Management of postoperative analgesia in elderly patients
    Frédéric Aubrun
    département d anesthésie réanimation chirurgicale, Universite Pierre et Marie Curie, Paris, France
    Reg Anesth Pain Med 30:363-79. 2005
  6. ncbi Sex- and age-related differences in morphine requirements for postoperative pain relief
    Frédéric Aubrun
    Department of Anesthesiology and Critical Care, Groupe Hospitalier Pitie Salpetriere, Assistance Publique Hopitaux de Paris, Universite Pierre et Marie Curie, France
    Anesthesiology 103:156-60. 2005
    ..Because of the wide variation in dose requirements for pain management, the authors conducted a prospective study in a large population and also assessed the effect of aging...
  7. ncbi A high initial VAS score and sedation after iv morphine titration are associated with the need for rescue analgesia
    Frédéric Aubrun
    département d anesthésie réanimation chirurgicale, CHU Pitie Salpetriere, 47 Boulevard de l Hopital, 75651 Paris Cedex 13, France
    Can J Anaesth 51:969-74. 2004
    ..We assessed pain after the end of iv morphine titration and studied the characteristics of patients who needed rescue sc morphine...
  8. ncbi [Intravenous morphine titration]
    F Aubrun
    département d anesthésie réanimation chirurgicale, Groupe Hospitalier Pitie Salpetriere, Assistance Publique Hopitaux de Paris, Universite Pierre et Marie Curie, 47 83, Boulevard de l Hopital, 75651 Paris 13, France
    Ann Fr Anesth Reanim 23:973-85. 2004
    ..To describe clinical implications in the operating room, postanaesthesia care unit (PACU), prehospital care, emergency and intensive care units (ICU), and cancerology. To provide recommendations for clinical practice...
  9. ncbi Adjunctive analgesia with intravenous propacetamol does not reduce morphine-related adverse effects
    F Aubrun
    Department of Anaesthesiology and Critical Care, Groupe Hospitalier Pitie Salpetriere, Assistance Publique Hopitaux de Paris AP HP, Universite Pierre et Marie Curie, Paris, France
    Br J Anaesth 90:314-9. 2003
    ..Propacetamol is widely used in the management of postoperative pain. It decreases morphine requirements but its effect on the incidence of morphine-related adverse effects remains unknown...
  10. ncbi Postoperative morphine consumption in the elderly patient
    Frédéric Aubrun
    Department of Orthopedic Surgery, Group Hospitalier Pitie Salpetriere, Assistance Publique Hopitaux de Paris, Universite Pierre et Marie Curie, Paris, France
    Anesthesiology 99:160-5. 2003
    ..It has been suggested that the dose of intravenous morphine used during postoperative titration is not modified by aging. The authors therefore studied morphine requirements in patients undergoing total hip replacement...
  11. ncbi What pain scales do nurses use in the postanaesthesia care unit?
    F Aubrun
    Universite Pierre et Marie Curie, département d anesthésie réanimation chirurgicale, CHU Pitie Salpetriere, Paris, France
    Eur J Anaesthesiol 20:745-9. 2003
    ..Nevertheless, in some clinical situations, this method may not be reliable. We performed an observational study to assess the use of the VAS and other pain scales by nurses in the postanaesthesia care unit...
  12. ncbi Relationships between measurement of pain using visual analog score and morphine requirements during postoperative intravenous morphine titration
    Frédéric Aubrun
    Department of Anesthesiology and Critical Care, Groupe Hospitalier Pitie Salpetriere, Assistance Publique Hopitaux de Paris, Universite Pierre et Marie Curie, France
    Anesthesiology 98:1415-21. 2003
    ....
  13. ncbi Postoperative titration of intravenous morphine in the elderly patient
    Frédéric Aubrun
    Department of Anesthesiology, Groupe Hospitalier Pitie Salpetriere, Assistance Publique Hopitaux de Paris, Universite Pierre et Marie Curie, France
    Anesthesiology 96:17-23. 2002
    ..Intravenous morphine titration is used to obtain rapid and complete postoperative pain relief. Whether this titration can be safely administered in the elderly patients remains a matter for debate...
  14. doi Relationships between plasma concentrations of morphine, morphine-3-glucuronide, morphine-6-glucuronide, and intravenous morphine titration outcomes in the postoperative period
    Hala Abou Hammoud
    Department of Pharmacology, University Pierre and Marie Curie Paris 6, Pitie Salpetriere Hospital, AP HP, Paris, France
    Fundam Clin Pharmacol 25:518-27. 2011
    ..This result suggests that the kinetics of morphine and its metabolites have limited value for explaining clinical effects of morphine in this clinical setting...
  15. ncbi The elderly patient and postoperative pain treatment
    Frédéric Aubrun
    Department of Anesthesiology and Critical Care, Groupe Hospitalier Pitie Salpetriere, Assistance Publique Hopitaux de Paris AP HP, Universite Pierre et Marie Curie Paris 6, Paris, France
    Best Pract Res Clin Anaesthesiol 21:109-27. 2007
    ..Sophisticated analgesic methods like PCA, regional analgesia and PCEA are not contraindicated in the elderly but pain relief and side effects should be monitored...
  16. doi Intravenous morphine titration to treat severe pain in the ED
    Virginie Lvovschi
    Department of Emergency Medicine and Surgery, Centre Hospitalo Universitaire Pitie Salpetriere, Assistance Publique Hôpitaux de Paris Université Pierre et Marie Curie Paris 6, 75013 Paris, France
    Am J Emerg Med 26:676-82. 2008
    ..We assessed the safety of intravenous morphine titration in the emergency setting...
  17. doi Intravenous morphine titration in immediate postoperative pain management: population kinetic-pharmacodynamic and logistic regression analysis
    Hala Abou Hammoud
    Pharmacology Department, Pitie Salpetriere Hospital, Assistance Publique Hopitaux de Paris, Universite Pierre et Marie Curie Paris 6, Paris, France
    Pain 144:139-46. 2009
    ..Our study supported the possibility of modeling the time course of a complex response in the absence of pharmacokinetic data. The current data should lead to a more rational management of the immediate postoperative pain...
  18. pmc Clinical review: management of difficult airways
    Olivier Langeron
    Department of Anesthesiology and Critical Care, Centre Hospitalier Universitaire Pitie Salpetriere, Assistance Publique Hopitaux de Paris, Universite Pierre et Marie Curie, Paris, France
    Crit Care 10:243. 2006
    ..The review will focus on basic airway management including preoxygenation, and on some oxygenation and tracheal intubation techniques that may be performed to solve a difficult airway...
  19. doi Objective assessment of the immediate postoperative analgesia using pupillary reflex measurement: a prospective and observational study
    Mourad Aissou
    Department of Anesthesia and Intensive Care, Assistance Publique, Hopitaux de Paris, St Antoine University Hospital, Paris, France
    Anesthesiology 116:1006-12. 2012
    ..We hypothesized that PDR could be a reliable index of pain intensity and could guide morphine administration in the immediate postoperative period...