Didier Auboeuf

Summary

Country: France

Publications

  1. ncbi Alteration of cyclin D1 transcript elongation by a mutated transcription factor up-regulates the oncogenic D1b splice isoform in cancer
    Gabriel Sanchez
    Institut National de la Sante et de la Recherche Medicale, Unité 685, Institut Universitaire d Hematologie, 1, avenue Claude Vellefaux, 75010 Paris, France
    Proc Natl Acad Sci U S A 105:6004-9. 2008
  2. ncbi Coregulators: transducing signal from transcription to alternative splicing
    Didier Auboeuf
    INSERM, U685 AVENIR, Centre G Hayem, Hopital Saint Louis, 1 avenue Claude Vellefaux, 75010 Paris, France
    Trends Endocrinol Metab 18:122-9. 2007
  3. ncbi A subset of nuclear receptor coregulators act as coupling proteins during synthesis and maturation of RNA transcripts
    Didier Auboeuf
    INSERM U685/AVENIR, Centre G. Hayem, , Paris, France
    Mol Cell Biol 25:5307-16. 2005
  4. ncbi Coupled alteration of transcription and splicing by a single oncogene: boosting the effect on cyclin D1 activity
    Gabriel Sanchez
    INSERM U685, Institut Universitaire d Hematologie, Paris, France
    Cell Cycle 7:2299-305. 2008
  5. ncbi Cotranscriptional splicing potentiates the mRNA production from a subset of estradiol-stimulated genes
    Danielle Bittencourt
    INSERM U685, Institut Universitaire d Hematologie, Hopital Saint Louis, 1 avenue Claude Vellefaux, 75010 Paris, France
    Mol Cell Biol 28:5811-24. 2008
  6. ncbi Splicing factor and exon profiling across human tissues
    Pierre de la Grange
    GenoSplice Technology, Centre Hayem, Hopital Saint Louis, 1 avenue Claude Vellefaux, 75010, Paris, France
    Nucleic Acids Res 38:2825-38. 2010
  7. ncbi Exon-based clustering of murine breast tumor transcriptomes reveals alternative exons whose expression is associated with metastasis
    Martin Dutertre
    INSERM UMRS 940, Paris, France
    Cancer Res 70:896-905. 2010
  8. ncbi Nonsense-mediated mRNA decay impacts MSI-driven carcinogenesis and anti-tumor immunity in colorectal cancers
    Jamila El-Bchiri
    INSERM, UMR S893, Team 13 Microsatellite Instability and Cancers, Paris, France
    PLoS ONE 3:e2583. 2008
  9. ncbi Regulation of H-ras splice variant expression by cross talk between the p53 and nonsense-mediated mRNA decay pathways
    Jérôme Barbier
    INSERM U685, Equipe Avenir, Hopital Saint Louis, 1 avenue Claude Vellefaux, Paris 75010, France
    Mol Cell Biol 27:7315-33. 2007
  10. ncbi Cotranscriptional exon skipping in the genotoxic stress response
    Martin Dutertre
    Institut National de Santé et de Recherche Médicale U590, Centre Leon Berard, Lyon, France
    Nat Struct Mol Biol 17:1358-66. 2010

Collaborators

Detail Information

Publications19

  1. ncbi Alteration of cyclin D1 transcript elongation by a mutated transcription factor up-regulates the oncogenic D1b splice isoform in cancer
    Gabriel Sanchez
    Institut National de la Sante et de la Recherche Medicale, Unité 685, Institut Universitaire d Hematologie, 1, avenue Claude Vellefaux, 75010 Paris, France
    Proc Natl Acad Sci U S A 105:6004-9. 2008
    ....
  2. ncbi Coregulators: transducing signal from transcription to alternative splicing
    Didier Auboeuf
    INSERM, U685 AVENIR, Centre G Hayem, Hopital Saint Louis, 1 avenue Claude Vellefaux, 75010 Paris, France
    Trends Endocrinol Metab 18:122-9. 2007
    ..Recent technical advances that help to elucidate the impact of stimuli on the exon content of regulated gene transcripts are also discussed...
  3. ncbi A subset of nuclear receptor coregulators act as coupling proteins during synthesis and maturation of RNA transcripts
    Didier Auboeuf
    INSERM U685/AVENIR, Centre G. Hayem, , Paris, France
    Mol Cell Biol 25:5307-16. 2005
  4. ncbi Coupled alteration of transcription and splicing by a single oncogene: boosting the effect on cyclin D1 activity
    Gabriel Sanchez
    INSERM U685, Institut Universitaire d Hematologie, Paris, France
    Cell Cycle 7:2299-305. 2008
    ..Thus, alterations of transcriptional regulators in disease may lead to splicing alterations. We review these data and discuss how this concept may apply to various factors that are altered in cancer...
  5. ncbi Cotranscriptional splicing potentiates the mRNA production from a subset of estradiol-stimulated genes
    Danielle Bittencourt
    INSERM U685, Institut Universitaire d Hematologie, Hopital Saint Louis, 1 avenue Claude Vellefaux, 75010 Paris, France
    Mol Cell Biol 28:5811-24. 2008
    ..quot; In contrast, we demonstrated for the first time that despite a strong transcriptional activation of the PS2 gene, the production of mRNA is not optimized owing to inefficient cotranscriptional RNA processing...
  6. ncbi Splicing factor and exon profiling across human tissues
    Pierre de la Grange
    GenoSplice Technology, Centre Hayem, Hopital Saint Louis, 1 avenue Claude Vellefaux, 75010, Paris, France
    Nucleic Acids Res 38:2825-38. 2010
    ....
  7. ncbi Exon-based clustering of murine breast tumor transcriptomes reveals alternative exons whose expression is associated with metastasis
    Martin Dutertre
    INSERM UMRS 940, Paris, France
    Cancer Res 70:896-905. 2010
    ..Our findings illustrate the utility of exon profiling to define novel theranostic markers for study in cancer progression and metastasis...
  8. ncbi Nonsense-mediated mRNA decay impacts MSI-driven carcinogenesis and anti-tumor immunity in colorectal cancers
    Jamila El-Bchiri
    INSERM, UMR S893, Team 13 Microsatellite Instability and Cancers, Paris, France
    PLoS ONE 3:e2583. 2008
    ....
  9. ncbi Regulation of H-ras splice variant expression by cross talk between the p53 and nonsense-mediated mRNA decay pathways
    Jérôme Barbier
    INSERM U685, Equipe Avenir, Hopital Saint Louis, 1 avenue Claude Vellefaux, Paris 75010, France
    Mol Cell Biol 27:7315-33. 2007
    ..In conclusion, we identified cross talk between the p53 and NMD pathways that regulates the expression levels of H-ras splice variants...
  10. ncbi Cotranscriptional exon skipping in the genotoxic stress response
    Martin Dutertre
    Institut National de Santé et de Recherche Médicale U590, Centre Leon Berard, Lyon, France
    Nat Struct Mol Biol 17:1358-66. 2010
    ..These data demonstrate genotoxic stress-induced alteration of the communication between the transcriptional and splicing machineries, which results in widespread exon skipping and plays a central role in the genotoxic stress response...
  11. ncbi A new advance in alternative splicing databases: from catalogue to detailed analysis of regulation of expression and function of human alternative splicing variants
    Pierre de la Grange
    INSERM U685 AVENIR, Centre G Hayem, Hopital Saint Louis, Paris, France
    BMC Bioinformatics 8:180. 2007
    ..Nevertheless, owing to the diversity of the transcriptome, there is a need for interactive databases that provide information about the potential function of each splicing variant, as well as its expression pattern...
  12. ncbi FAST DB: a website resource for the study of the expression regulation of human gene products
    Pierre de la Grange
    INSERM U685/AVENIR, Centre G. Hayem, , , 1 avenue Claude Vellefaux, 75010 Paris, France
    Nucleic Acids Res 33:4276-84. 2005
    ..FAST DB has been designed to facilitate studies that integrate transcriptional and post-transcriptional events to investigate the expression regulation of human gene products...
  13. ncbi Differential recruitment of nuclear receptor coactivators may determine alternative RNA splice site choice in target genes
    Didier Auboeuf
    Department of Molecular and Cellular Biology, Division of Diabetes, Endocrinology, and Metabolism, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA
    Proc Natl Acad Sci U S A 101:2270-4. 2004
    ....
  14. ncbi CoAA, a nuclear receptor coactivator protein at the interface of transcriptional coactivation and RNA splicing
    Didier Auboeuf
    Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas 77030, USA
    Mol Cell Biol 24:442-53. 2004
    ..This contributes to the promoter-preferential effects mediated by CoAA on RNA splicing during the course of steroid hormone action...
  15. ncbi Coactivator/corepressor ratios modulate PR-mediated transcription by the selective receptor modulator RU486
    Zheng Liu
    Department of Molecular and Cellular Biology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA
    Proc Natl Acad Sci U S A 99:7940-4. 2002
    ....
  16. ncbi ASEtrap: a biological method for speeding up the exploration of spliceomes
    Gilbert Thill
    Genoscope Centre National de Séquençage and Centre National de la Recherche Scientifique CNRS Unité Mixte de Recherche UMR 8030, 91000 Evry, France
    Genome Res 16:776-86. 2006
    ..Thus, it appears that ASEtrap has the potential to greatly facilitate the determination of the total complement of splice variants expressed in human, as well as other organisms...
  17. ncbi Steroid hormone receptor coactivation and alternative RNA splicing by U2AF65-related proteins CAPERalpha and CAPERbeta
    Dennis H Dowhan
    Department of Molecular and Cellular Biology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA
    Mol Cell 17:429-39. 2005
    ..These results indicate that steroid hormone receptor-regulated transcription and pre-mRNA splicing can be directly linked through dual function coactivator molecules such as CAPERalpha and CAPERbeta...
  18. ncbi Coordinate regulation of transcription and splicing by steroid receptor coregulators
    Didier Auboeuf
    Department of Molecular and Cellular Biology, Department of Biochemistry and Molecular Biology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA
    Science 298:416-9. 2002
    ....
  19. ncbi Regulation of alternative splicing by the ATP-dependent DEAD-box RNA helicase p72
    Arnd Honig
    Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, Texas 77030, USA
    Mol Cell Biol 22:5698-707. 2002
    ..In agreement with this hypothesis, p72 was not able to restore the inclusion of an exon mutated for its major enhancer element. Our results suggest that RNA helicases may be important alternative splicing regulatory factors...