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Genomes and GenesSpecies | Henri Jean AubinSummaryCountry: France Publications
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Pharmacotherapy for smoking cessation: present and futureHenri Jean Aubin
Substance Abuse Treatment Center, Hopital Paul Brousse, Hôpitaux Universitaires Paris Sud, AP HP, INSERM U 669 UniversityParis Sud, 12 Avenue Paul Vaillant Couturier 94800 Villejuif, France
Curr Pharm Des 17:1343-50. 2011..Clonidine and nortriptyline have been proposed as second-line medications. In addition, this review indentifies a series of promising drugs that hopefully will be available to complete our current armory...- Management of emergent psychiatric symptoms during smoking cessationHenri Jean Aubin
Hôpital Emile Roux, Assistance Publique Hopitaux de Paris, Limeil Brevannes, France
Curr Med Res Opin 25:519-25. 2009..However, smoking cessation causes nicotine withdrawal syndrome, a condition with symptoms that overlap those of major depression and anxiety disorders... - [Validity and use of biological marker tests for alcoholism]Henri-Jean Aubin
Centre de Traitement des Addictions, hopital Emile-Roux, 94456 Limell-Brevannes Cedex
Rev Prat 56:1065. 2006 
Factors associated with higher body mass index, weight concern, and weight gain in a multinational cohort study of smokers intending to quitHenri Jean Aubin
Assistance Publique Hopitaux de Paris, Hopital Paul Brousse, 94804 Villejuif Cedex, France
Int J Environ Res Public Health 6:943-57. 2009..Quit attempts were more frequent in subjects with a high baseline BMI and low weight concerns...- Varenicline versus transdermal nicotine patch for smoking cessation: results from a randomised open-label trialH J Aubin
Hôpital Emile Roux, Assistance Publique Hopitaux de Paris, Limeil Brevannes, Paris, France
Thorax 63:717-24. 2008..A study was undertaken to compare a 12-week standard regimen of varenicline with a 10-week standard regimen of transdermal nicotine replacement therapy (NRT) for smoking cessation... - Characteristics of tobacco withdrawal in pregnant womenGilles Grange
Maternite Port Royal, Groupe Hospitalier Cochin Saint Vincent De Paul, APHP, Paris, France
Eur J Obstet Gynecol Reprod Biol 125:38-43. 2006..To describe the management of tobacco withdrawal in pregnant women... - Lazabemide, a selective, reversible monoamine oxidase B inhibitor, as an aid to smoking cessationIvan Berlin
Departement de Pharmacologie, Centre Hospitalo Universitaire Pitie Salpetriere, Paris, France
Addiction 97:1347-54. 2002..This is probably due to some components of tobacco smoke. When smokers quit, MAOB activity returns to normal. Reduced MAO activity may increase nicotine's addictive potential... - The Modified Reasons for Smoking Scale: factorial structure, gender effects and relationship with nicotine dependence and smoking cessation in French smokersIvan Berlin
Departement de Pharmacologie, Centre Hospitalier Universitaire Pitie Salpetriere, Paris, France
Addiction 98:1575-83. 2003.... - Impulsivity in smoking, nonsmoking, and ex-smoking alcoholicsMarilyn D Skinner
Centre de Traitement des Addictions, Hôpital Emile Roux, 1 Avenue de Verdun, 94456 Limeil Brévannes, France
Addict Behav 29:973-8. 2004..In addition, stopping smoking may diminish impulsivity levels in alcoholics. Routine testing of impulsivity in current alcoholic smokers might predict who might successfully become an ex-smoker... - [Current therapeutic strategies for tobacco dependence]Henri Jean Aubin
Hopital Paul Brousse, centre d addictologie, AP HP, INSERM U669, Universite Paris Sud, 94804 Villejuif Cedex
Rev Prat 62:347-9, 352-3. 2012..Recent guidelines stress the responsibility of all health care professional to address the smoking problem of every patient through the 5 A model: Ask - Advise - Assess - Assist - Arrange... - French-language version of the World Health Organization quality of life spirituality, religiousness and personal beliefs instrumentOlfa Mandhouj
INSERM U699, Paris, France
Health Qual Life Outcomes 10:39. 2012..We developed and assessed the validity of a French-language version of the World Health Organization Quality of Life Spirituality, Religiousness and Personal Beliefs Instrument (WHOQOL-SRPB)... - Weight gain in smokers after quitting cigarettes: meta-analysisHenri Jean Aubin
Centre d enseignement, de Recherche et de Traitement des Addictions, Hopital Paul Brousse, AP HP, Univ Paris Sud, INSERM U669, 94804 Villejuif, France
BMJ 345:e4439. 2012..To describe weight gain and its variation in smokers who achieve prolonged abstinence for up to 12 months and who quit without treatment or use drugs to assist cessation... - [Current strategies for treatment of alcohol problems]Henri Jean Aubin
Hopital Paul Brousse, addictologie, 94804 Villejuif Cedex
Rev Prat 61:1373-7. 2011..The next step is relapse prevention, for which only three medications are currently validated in France, acamprosate, naltrexone, and disulfiram... 
Effect of the threat of a disulfiram-ethanol reaction on cue reactivity in alcoholicsMarilyn D Skinner
Centre Hospitalier Emile Roux, Centre de Traitement des Addictions, Limeil Brevannes, France
Drug Alcohol Depend 112:239-46. 2010..Little is known about the effect of disulfiram on subjective and autonomic nervous system cue reactivity in the laboratory. The dissuasive psychological effect manifested as a threat would seem to prevail over the pharmacological effect...- Tolerability and safety of sustained-release bupropion in the management of smoking cessationHenri Jean Aubin
Centre de Traitement des Addictions, Hôpital Emile Roux, 1 Avenue de Verdun, 94456 Limeil Brévannes, France
Drugs 62:45-52. 2002..The most common adverse events (insomnia and dry mouth) are generally transient and often resolve quickly without therapeutic intervention; they can be managed if necessary by a reduction in bupropion dose... - [Current pharmacotherapies and immunotherapy in cocaine addiction]Laurent Karila
Universite Paris Sud, F 94276 Le Kremlin Bicetre, France
Presse Med 37:689-98. 2008..However, this must be confirmed in larger patient populations... - Pharmacological approaches to methamphetamine dependence: a focused reviewLaurent Karila
Addiction Research and Treatment Center, Paul Brousse Hospital, Paris XI University, AP HP, CEA INSERM U1000, Villejuif, France
Br J Clin Pharmacol 69:578-92. 2010..Despite the lack of success in most studies to date, increasing efforts are being made to develop medications for the treatment of methamphetamine dependence and several promising agents are targets of further research... - [Drug addiction and addictive behavior. Part 2 - alcohol, psychoactive and illicit substances]Laurent Karila
, , F-94276, France
Rev Prat 58:1131-40; quiz 1149. 2008 - Ethyl glucuronide for detecting alcohol lapses in patients with an alcohol use disorderPierre Lahmek
Centre de Traitement des Addictions, Hôpital Emile Roux 1 Avenue de Verdun 94450 Limeil Brévannes cedex, France
J Addict Med 6:35-8. 2012..5%) reported recent alcohol consumption; 12 (54.5%) gave a negative breath alcohol test and declared no alcohol lapse. Ethyl glucuronide has been found useful in detecting covered lapses... - Smoking, quitting, and psychiatric disease: a reviewHenri Jean Aubin
Hôpital Emile Roux, Assistance Publique Hopitaux de Paris, Limeil Brevannes, France
Neurosci Biobehav Rev 36:271-84. 2012..Furthermore, the complicated relationship observed between nicotine dependence, nicotine withdrawal symptoms, and mental illness necessitates integration of close monitoring in any successful smoking cessation program... - Determinants of improvement in quality of life of alcohol-dependent patients during an inpatient withdrawal programmePierre Lahmek
Centre de Traitement des Addictions, Hôpital Emile Roux, Assistance Publique Hopitaux de Paris, 94450 Limeil Brevannes, France
Int J Med Sci 6:160-7. 2009.... - [Cognitive modifications associated with tobacco smoking]Marie Lecacheux
Universite Paris Sud, Le Kremlin Bicetre, INSERM U669, Paris, Hopital Paul Brousse, Villejuif, France
Presse Med 38:1241-52. 2009..It is associated with cognitive disorders which tend to maintain addictive mechanisms. In the short term, the nicotine contained in tobacco enhances attention and memory... - A seizure attributed to ofloxacine in a woman undergoing detoxification for alcohol dependencePierre Lahmek
Centre de Traitement des Addictions, Hôpital Emile Roux, Assistance Publique Hopitaux de Paris, 94450 Limeil Brevannes, France
Case Report Med 2009:705635. 2009.... - Is baclofen a revolutionary medication in alcohol addiction management? Review and recent updatesMohamed Ali Gorsane
INSERM, U669, Paris, France
Subst Abus 33:336-49. 2012..Thus, baclofen should benefit from further studies of its biobehavioral mechanisms, dose-response effect, and indications in various alcoholic patient profiles... - [From nicotine dependence to addictology]Henri Jean Aubin
Hopital Paul Brousse, centre d addictologie, AP HP, INSERM U669, Universite Paris Sud, 94804 Villejuif Cedex
Rev Prat 62:356-9. 2012..Despite what is commonly thought, tobacco is the most addictive amongst all psycho-active-substances in Western countries... - Craving's place in addiction theory: contributions of the major modelsMarilyn D Skinner
Centre de Traitement des Addictions, Centre Hospitalier Emile Roux, 1 Avenue de Verdun, 94456 Limeil Brévannes, France
Neurosci Biobehav Rev 34:606-23. 2010..It is well accepted that no single model explains craving completely, suggesting that a solid understanding of the phenomenon will only occur with consideration from multiple angles. A reformulated definition of craving is proposed... - Amisulpride does not prevent relapse in primary alcohol dependence: results of a pilot randomized, placebo-controlled trialDonata Marra
Department of Pharmacology and Psychiatry, Hospital Pritié Salpêtrière, Paris, France
Alcohol Clin Exp Res 26:1545-52. 2002..The mesolimbic dopamine system is known to play an important role in alcohol dependence. Amisulpride, a substituted benzamide, seems to facilitate dopaminergic neurotransmission at low doses... - Harmful alcohol consumption and patterns of substance use in HIV-infected patients receiving antiretrovirals (ANRS-EN12-VESPA Study): relevance for clinical management and interventionLaurent Michel
Health and Medical Research National Institute, Paris, France
AIDS Care 22:1136-45. 2010..Such interventions for alcohol risk reduction remain central to promoting improved HIV prevention and assuring HAART effectiveness in these populations... - The French Observational Cohort of Usual Smokers (FOCUS) cohort: French smokers perceptions and attitudes towards smoking cessationHenri Jean Aubin
Hôpital Paul Brousse AP HP, Villejuif, France, Hôpital Emile Roux AP HP, Limeil Brevannes, INSEM U699, France
BMC Public Health 10:100. 2010..Despite increasing governmental anti-smoking measures, smoking prevalence remains at a high level in France... - The 3' part of the dopamine transporter gene DAT1/SLC6A3 is associated with withdrawal seizures in patients with alcohol dependenceYann Le Strat
INSERM U675, IFR02, Faculté de Médecine Xavier Bichat Université, Henri Huchard, Paris, France
Alcohol Clin Exp Res 32:27-35. 2008..We investigated whether polymorphisms within the DAT1 gene are associated with WS taking into account some of the confounding factors such as the severity of alcohol dependence... - Description of tobacco addiction in pregnant womenGilles Grange
Maternite Port Royal, Groupe Hospitalier Cochin Saint Vincent De Paul, Paris, France Association Alliés, 20 Bd Malesherbes, 75017 Paris, France
Eur J Obstet Gynecol Reprod Biol 120:146-51. 2005..To compare the characteristics of a group of pregnant women who smoked until delivery with women who gave up smoking during pregnancy... - Brain morphometry and cognitive performance in detoxified alcohol-dependents with preserved psychosocial functioningSandra Chanraud
Inserm U 797, CEA INSERM Research Unit Neuroimaging and Psychiatry, Institute for Health and Medical Research and Atomic Energy Commission Hospital Department Frédéric Joliot, IFR49, Univ Paris Sud, Univ Paris 5, Orsay, France
Neuropsychopharmacology 32:429-38. 2007..Besides involving frontal regions, these findings are consistent with a cerebello-thalamo-cortical model of impaired executive functions in alcohol-dependent individuals... - [Current therapeutic strategies in smoking cessation]Anne Borgne
Unité de Coordination de Tabacologie, Hopital Jean Verdier, 93144 Bondy Cedex
Rev Prat 54:1883-93. 2004..Before reaching the decision to quit, the smoker goes through a process in the course of which the role of health professionals' advice is paramount... - Comparison of the effects of a 24-hour nicotine patch and a 16-hour nicotine patch on smoking urges and sleepHenri-Jean Aubin
Centre de Traitement des Addictions, , Limeil Brevannes, France
Nicotine Tob Res 8:193-201. 2006..The present findings do not support the idea that nicotine delivery during bedtime might disturb sleep, but rather it improves restorative sleep and postwaking arousal... - [Behavioral and cognitive therapy to break the smoking habit. Review of the literature]Bernard Le Foll
Unité de Neurobiologie et Pharmacologie Moléculaire de l INSERM, Centre Paul Broca, 2 ter, rue d Alesia, 75014 Paris, France
Ann Med Interne (Paris) 153:1S32-40. 2002..This article reviews these techniques and presents the results of a recent meta-analysis evaluating their efficacy. These results confirm the efficacy of behavioral and cognitive therapy in smoking cessation... - A pilot evaluation of the safety and tolerability of repeat dose administration of long-acting injectable naltrexone (Vivitrex) in patients with alcohol dependenceBankole A Johnson
University of Texas Health Science Center at San Antonio, San Antonio, Texas 78229 3900, USA
Alcohol Clin Exp Res 28:1356-61. 2004..A long-acting injectable naltrexone formulation (Vivitrex) was designed to facilitate patient adherence by providing an extended duration of therapeutic naltrexone over 1 month, thereby eliminating the need for daily dosing... - Double-blind study of cyamemazine and diazepam in the alcohol withdrawal syndromeJean-Daniel Favre
Service de Psychiatrie, , Clamart, France
Hum Psychopharmacol 20:511-9. 2005..CONCLUSIONS: Cyamemazine showed similar efficacy and tolerability to diazepam for the treatment of alcohol withdrawal symptoms at therapeutic doses in the range 100-300 mg. Copyright (c) 2005 John Wiley & Sons, Ltd... - Blocking cannabinoid CB1 receptors for the treatment of nicotine dependence: insights from pre-clinical and clinical studiesBernard Le Foll
Translational Addiction Research Laboratory, Centre for Addiction and Mental Health, University of Toronto, Toronto, Canada
Addict Biol 13:239-52. 2008..Rimonabant also appears to decrease relapse rates in smokers. These findings indicate significant, but limited, utility of rimonabant for smoking cessation...