- Diagnosis, disease course, and management of patients with Kleine-Levin syndromeIsabelle Arnulf
National Reference Center for Narcolepsy, Idiopathic Hypersomnia and Kleine Levin Syndrome, Sleep Disorders Unit and Inserm U975, Pitié Salpêtrière Hospital APHP, Pierre and Marie Curie University, Paris, France
Lancet Neurol 11:918-28. 2012..Functional imaging studies have revealed hypoactivity in thalamic and hypothalamic regions, and in the frontal and temporal lobes. Stimulants and mood stabilisers can be beneficial in the treatment of severe cases...