I Arnulf

Summary

Country: France

Publications

  1. ncbi request reprint [Normal and disordered sleep]
    I Arnulf
    Fédération des pathologies du sommeil, Hopital de la Pitie Salpetriere, Assistance Publique Hopitaux de Paris, 47 83, Boulevard de l Hopital, F 75651 Paris Cedex 13
    Ann Pharm Fr 65:239-50. 2007
  2. doi request reprint REM sleep behavior disorder: motor manifestations and pathophysiology
    Isabelle Arnulf
    Sleep Disorders Unit, Pitie Salpetriere Hospital, Pierre and Marie Curie University, Inserm U975, CRicm, Paris, France
    Mov Disord 27:677-89. 2012
  3. doi request reprint The 'scanning hypothesis' of rapid eye movements during REM sleep: a review of the evidence
    I Arnulf
    Unité des pathologies du sommeil, Hopital Pitie Salpetriere, Paris, France
    Arch Ital Biol 149:367-82. 2011
  4. doi request reprint Ring the bell for Matins: circadian adaptation to split sleep by cloistered monks and nuns
    Isabelle Arnulf
    Sleep Disorders Unit, Pitie Salpetriere Hospital, aph, Paris, France
    Chronobiol Int 28:930-41. 2011
  5. ncbi request reprint CSF versus serum leptin in narcolepsy: is there an effect of hypocretin deficiency?
    Isabelle Arnulf
    Center for Narcolepsy, Department of Psychiatry and Behavioral Sciences, Stanford University, Palo Alto, CA, USA
    Sleep 29:1017-24. 2006
  6. doi request reprint Kleine-Levin syndrome: a systematic study of 108 patients
    Isabelle Arnulf
    Stanford Center for Narcolepsy and Howard Hughes Medical Institute, Stanford University, Palo Alto, CA, USA
    Ann Neurol 63:482-93. 2008
  7. doi request reprint Sleepiness in Parkinson's disease
    Isabelle Arnulf
    Sleep Disorders Unit and Inserm UMR 975, Pitie Salpetriere Hospital, Assistance Publique Hopitaux de Paris, Paris 6 University, Paris, France
    Parkinsonism Relat Disord 15:S101-4. 2009
  8. doi request reprint Sleep induced by stimulation in the human pedunculopontine nucleus area
    Isabelle Arnulf
    Sleep Disorders Unit, Institut National de la Santé et de la Recherche Médicale INSERM UMR_975 Mixed Unity of Research, Pitie Salpetriere Hospital, Assistance Publique Hopitaux de Paris, Paris 6 University, Paris, France
    Ann Neurol 67:546-9. 2010
  9. doi request reprint [REM sleep behavior disorder: an overt access to motor and cognitive control during sleep]
    I Arnulf
    Unité des pathologies du sommeil, Hopital Pitie Salpetriere, Groupe Hospitalier de la Pitié Salpêtrière, 47 83 boulevard de l Hopital, 75651 Paris Cedex 13, France
    Rev Neurol (Paris) 166:785-92. 2010
  10. pmc Evidence for the re-enactment of a recently learned behavior during sleepwalking
    Delphine Oudiette
    Sleep Disorders Unit, Pitie Salpetriere Hospital, APHP, Paris, France
    PLoS ONE 6:e18056. 2011

Collaborators

Detail Information

Publications35

  1. ncbi request reprint [Normal and disordered sleep]
    I Arnulf
    Fédération des pathologies du sommeil, Hopital de la Pitie Salpetriere, Assistance Publique Hopitaux de Paris, 47 83, Boulevard de l Hopital, F 75651 Paris Cedex 13
    Ann Pharm Fr 65:239-50. 2007
    ..g. psychiatric insomnia, restless legs syndrome)...
  2. doi request reprint REM sleep behavior disorder: motor manifestations and pathophysiology
    Isabelle Arnulf
    Sleep Disorders Unit, Pitie Salpetriere Hospital, Pierre and Marie Curie University, Inserm U975, CRicm, Paris, France
    Mov Disord 27:677-89. 2012
    ..They constitute a highly specific target for testing neuroprotective agents...
  3. doi request reprint The 'scanning hypothesis' of rapid eye movements during REM sleep: a review of the evidence
    I Arnulf
    Unité des pathologies du sommeil, Hopital Pitie Salpetriere, Paris, France
    Arch Ital Biol 149:367-82. 2011
    ..These results are consistent with the model of a brainstem generator activating simultaneously images, sounds, limbs movements and REMs in a coordinated parallel manner, as in a virtual reality...
  4. doi request reprint Ring the bell for Matins: circadian adaptation to split sleep by cloistered monks and nuns
    Isabelle Arnulf
    Sleep Disorders Unit, Pitie Salpetriere Hospital, aph, Paris, France
    Chronobiol Int 28:930-41. 2011
    ..It resembles the biphasic sleep and rhythm of healthy volunteers transferred to a short (10-h) photoperiod and provides a living glance into the sleep pattern of medieval time...
  5. ncbi request reprint CSF versus serum leptin in narcolepsy: is there an effect of hypocretin deficiency?
    Isabelle Arnulf
    Center for Narcolepsy, Department of Psychiatry and Behavioral Sciences, Stanford University, Palo Alto, CA, USA
    Sleep 29:1017-24. 2006
    ..To determine if hypocretin deficiency is associated with abnormally low serum leptin levels, a putative cause of increased body mass index in narcoleptics...
  6. doi request reprint Kleine-Levin syndrome: a systematic study of 108 patients
    Isabelle Arnulf
    Stanford Center for Narcolepsy and Howard Hughes Medical Institute, Stanford University, Palo Alto, CA, USA
    Ann Neurol 63:482-93. 2008
    ..Kleine-Levin syndrome is a rare disorder characterized by relapsing-remitting episodes of hypersomnia, cognitive disturbances, and behavioral disturbances, such as hyperphagia and hypersexuality...
  7. doi request reprint Sleepiness in Parkinson's disease
    Isabelle Arnulf
    Sleep Disorders Unit and Inserm UMR 975, Pitie Salpetriere Hospital, Assistance Publique Hopitaux de Paris, Paris 6 University, Paris, France
    Parkinsonism Relat Disord 15:S101-4. 2009
    ..Eventually, the recent stimulation of the pedunculopontine nucleus has stimulant or sedative effects in patients, depending on the frequency of stimulation. These results provide new insights into the mechanisms of arousal in PD...
  8. doi request reprint Sleep induced by stimulation in the human pedunculopontine nucleus area
    Isabelle Arnulf
    Sleep Disorders Unit, Institut National de la Santé et de la Recherche Médicale INSERM UMR_975 Mixed Unity of Research, Pitie Salpetriere Hospital, Assistance Publique Hopitaux de Paris, Paris 6 University, Paris, France
    Ann Neurol 67:546-9. 2010
    ..In addition, the sudden withdrawal of the low-frequency stimulation was consistently followed by rapid eye movement sleep episodes in 1 patient. These data have the potential to benefit patients who suffer from sleep disorders...
  9. doi request reprint [REM sleep behavior disorder: an overt access to motor and cognitive control during sleep]
    I Arnulf
    Unité des pathologies du sommeil, Hopital Pitie Salpetriere, Groupe Hospitalier de la Pitié Salpêtrière, 47 83 boulevard de l Hopital, 75651 Paris Cedex 13, France
    Rev Neurol (Paris) 166:785-92. 2010
    ....
  10. pmc Evidence for the re-enactment of a recently learned behavior during sleepwalking
    Delphine Oudiette
    Sleep Disorders Unit, Pitie Salpetriere Hospital, APHP, Paris, France
    PLoS ONE 6:e18056. 2011
    ..Our observation also suggests that the study of such sleep disorders may provide unique and critical information about cognitive functions operating during sleep...
  11. doi request reprint Hallucinations in narcolepsy with and without cataplexy: contrasts with Parkinson's disease
    Smaranda Leu-Semenescu
    Sleep Disorders Unit, Pitie Salpetriere Hospital, AP HP, Paris 6 University, Paris, France
    Sleep Med 12:497-504. 2011
    ..partial (PD, narcolepsy without cataplexy) hypocretin-1 deficiency...
  12. doi request reprint Rapid eye movement sleep disturbances in Huntington disease
    Isabelle Arnulf
    Pathologies du Sommeil, Groupe Hospitalier Pitie Salpetriere, Assistance Publique Hopitaux de Paris AP HP, and U106, University Pierre and Marie Curie, Paris Cedex 13, France
    Arch Neurol 65:482-8. 2008
    ..Sleep disorders including insomnia, movements during sleep, and daytime sleepiness are common but poorly studied in Huntington disease (HD)...
  13. ncbi request reprint Effect of low and high frequency thalamic stimulation on sleep in patients with Parkinson's disease and essential tremor
    I Arnulf
    centre d investigation clinique, Fédération de Neurologie and INSERM U 289, Paris, France
    J Sleep Res 9:55-62. 2000
    ..Our results also suggest that low frequency stimulation applied in the region of the reticular nuclei does not induce sleep...
  14. ncbi request reprint Improvement of sleep architecture in PD with subthalamic nucleus stimulation
    I Arnulf
    centre d investigation clinique, Fédération de Neurologie and INSERM U289, Paris, France
    Neurology 55:1732-4. 2000
    ..Total sleep time increased by 47%; wakefulness after sleep onset decreased by 51 minutes. Insomnia in patients with PD may predominantly result from nighttime motor disability...
  15. doi request reprint Residual sleepiness in obstructive sleep apnoea: phenotype and related symptoms
    C Vernet
    Sleep Disorders Unit, UMR 975, National Reference Centre for Narcolepsy and Hypersomnia, Paris, France
    Eur Respir J 38:98-105. 2011
    ..The association between RES, periodic leg movements, apathy and depressive mood parallels the post-hypoxic lesions in noradrenaline, dopamine and serotonin systems in animals exposed to intermittent hypoxia...
  16. ncbi request reprint Neurokinin B, neurotensin, and cannabinoid receptor antagonists and Parkinson disease
    V Mesnage
    centre d investigation clinique, Fédération de Neurologie and Inserm, Paris, France
    Clin Neuropharmacol 27:108-10. 2004
    ..In this exploratory randomized, double-blind, placebo-controlled study, at the dose used, the drugs tested were well tolerated and could not improve parkinsonian motor disability...
  17. ncbi request reprint Parkinson's disease and sleepiness: an integral part of PD
    I Arnulf
    Fédération des pathologies du sommeil, Hopital Pitie Salpetriere, Assistance Publique Hopitaux de Paris, France
    Neurology 58:1019-24. 2002
    ..To investigate the potential causes of excessive daytime sleepiness in patients with PD-poor sleep quality, abnormal sleep-wakefulness control, and treatment with dopaminergic agents...
  18. doi request reprint Does clinical rapid eye movement behavior disorder predict worse outcomes in Parkinson's disease?
    S Lavault
    Unité des pathologies du sommeil, Assistance Publique Hopitaux de Paris APHP, Paris, France
    J Neurol 257:1154-9. 2010
    ..The fluctuation and disappearance of clinical RBD in some patients may be due to functional abnormalities rather than lesions...
  19. ncbi request reprint Chronic hiccups and sleep
    I Arnulf
    Service de Pneumologie et Laboratoire du Sommeil, , Paris, France
    Sleep 19:227-31. 1996
    ..Hiccups themselves were not responsible for any arousals or awakenings. We conclude that neural mechanisms responsible for hiccups are strongly influenced by sleep state and that hiccups disrupt sleep onset but not established sleep...
  20. ncbi request reprint Unawareness of naps in Parkinson's disease and in disorders with excessive daytime sleepiness
    M Merino-Andreu
    Fédération des Pathologies du Sommeil and Upres EA 2397, Hopital Pitie Salpetriere, Assistance Publique Hopitaux de Paris, Paris, France
    Neurology 60:1553-4. 2003
  21. ncbi request reprint Severe restless legs syndrome presenting as intractable insomnia
    I Arnulf
    Fédération des pathologies du sommeil, Hopital Pitie Salpetriere, 47 83 boulevard de l Hopital, 75651 Paris Cedex 13, France
    Neurology 62:E19. 2004
  22. ncbi request reprint Sleep disorders and diaphragmatic function in patients with amyotrophic lateral sclerosis
    I Arnulf
    Service de Pneumologie, UPRES EA 2397, Explorations Fonctionnelles Respiratoires, Neurologie et Explorations Fonctionnelles du Systeme Nerveux, Groupe Hospitalier Pitie Salpetriere, Paris, France
    Am J Respir Crit Care Med 161:849-56. 2000
    ..Median survival time was dramatically shorter (217 d) in Group 1 than in Group 2 (619 d, p = 0.015)...
  23. pmc Parkinson's disease with camptocormia
    F Bloch
    Centre d Investigation Clinique Fédération des Maladies du Système Nerveux, Groupe Hospitalier Pitie Salpetriere, Paris, France
    J Neurol Neurosurg Psychiatry 77:1223-8. 2006
    ..The origin of the disorder is unknown, but it is usually attributed either to a primary or a secondary paravertebral muscle myopathy or a motor neurone disorder. Camptocormia is also observed in a minority of patients with parkinsonism...
  24. doi request reprint [Narcolepsy with cataplexy in the child: clinical evaluation and therapeutical management]
    M Lecendreux
    centre pédiatrique des pathologies du sommeil, Hopital Robert Debre, Paris, France
    Rev Neurol (Paris) 164:646-57. 2008
    ....
  25. ncbi request reprint Vivid dreams, hallucinations, psychosis and REM sleep in Guillain-Barré syndrome
    V Cochen
    Federation de Neurologie, Hopital Henri Mondor, Assistance Publique Hopitaux de Paris, Paris, France
    Brain 128:2535-45. 2005
    ..Sleep studies suggest that mental status abnormalities are wakeful dreams caused by a sleep and dream-associated disorder (status dissociatus)...
  26. doi request reprint Nonviolent elaborate behaviors may also occur in REM sleep behavior disorder
    D Oudiette
    Sleep Disorders Unit, Pitie Salpetriere Hospital, APHP, Team 106, CRicm, and Paris 6 University, France
    Neurology 72:551-7. 2009
    ..To document unusual, nonviolent behaviors during REM sleep behavior disorder (RBD) and evaluate their frequency in Parkinson disease (PD)...
  27. ncbi request reprint [Psychic disorders and somnolence]
    J L Houeto
    Federation de Neurologie, centre d investigation clinique, Groupe Hospitalier Pitie Salpetriere, Paris, France
    Rev Neurol (Paris) 158:S102-7. 2002
    ....
  28. ncbi request reprint [Sleep disorders during synucleopathies and taupathies]
    I Arnulf
    Fédération des pathologies du sommeil, Hopital Pitie Salpetriere, Assistance Publique Hopitaux de Paris
    Rev Neurol (Paris) 159:6S77-82. 2003
    ..Recent evidences suggest that they may result from non dopaminergic lesions, including cholinergic neurons in the locus subcoeruleus and orexinergic neurons in the lateral hypothalamus...
  29. doi request reprint [Restless-legs syndrome]
    E Karroum
    UF pathologies du sommeil, Groupe Hospitalier Pitie Salpetriere, Assistance Publique Hopitaux de Paris, Pavillon Marguerite Bottard, Paris Cedex, France
    Rev Neurol (Paris) 164:701-21. 2008
    ..In severe, refractory or neuropathy-associated RLS, antiepileptic (gabapentin, pregabalin) or opioid (oxycodone, tramadol) drugs can be used...
  30. ncbi request reprint Kleine-Levin syndrome: a systematic review of 186 cases in the literature
    I Arnulf
    Stanford University Center for Narcolepsy, Palo Alto, CA, USA
    Brain 128:2763-76. 2005
    ..In conclusion, KLS is a unique disease which may be more severe in female and secondary cases...
  31. ncbi request reprint Hyperoxia increases paradoxical sleep rhythm in the pontine cat
    I Arnulf
    UPRESS EA2397, Pitie Salpetriere Hospital, Paris, France
    Brain Res 807:160-6. 1998
    ..These findings show that PS is exquisitely sensitive to conditions that impair oxidative metabolism. The role of cholinergic executive PS systems as putative metabolic-sensitive neurons remains to be established...
  32. doi request reprint [Acute exacerbation of restless legs syndrome during perioperative procedures: case reports and suggested management]
    E G Karroum
    Unité des pathologies du sommeil, Groupe Hospitalier Pitie Salpetriere, AP HP, 47 83, Boulevard de l Hopital, 75651 Paris Cedex 13, France
    Ann Fr Anesth Reanim 29:920-4. 2010
    ....
  33. ncbi request reprint Clinical predictive factors of subthalamic stimulation in Parkinson's disease
    M L Welter
    Centre d Investigation Clinique and INSERM U 289, Hopital de la Salpetriere, Paris, France
    Brain 125:575-83. 2002
    ....
  34. doi request reprint Do the eyes scan dream images during rapid eye movement sleep? Evidence from the rapid eye movement sleep behaviour disorder model
    Laurène Leclair-Visonneau
    Sleep Disorder Unit, Pitie Salpetriere Hospital, Assistance Publique Hopitaux de Paris, 75013 Paris, France
    Brain 133:1737-46. 2010
    ..Since the rapid eye movements are similar in subjects with and without rapid eye movement sleep behaviour disorder, this concordance can be extended to normal rapid eye movement sleep...
  35. ncbi request reprint Disappearance of "phantom limb" and amputated arm usage during dreaming in REM sleep behaviour disorder
    R Vetrugno
    J Neurol Neurosurg Psychiatry 79:481-3. 2008