X Anglaret

Summary

Country: France

Publications

  1. pmc Early upper digestive tract side effects of zidovudine with tenofovir plus emtricitabine in West African adults with high CD4 counts
    Eric Ouattara
    Programme PACCI, Abidjan, Côte d Ivoire Univ Bordeaux, ISPED, F 33000 Bordeaux, France
    J Int AIDS Soc 16:18059. 2013
  2. pmc Patient- and population-level health consequences of discontinuing antiretroviral therapy in settings with inadequate HIV treatment availability
    April D Kimmel
    Department of Healthcare Policy and Research, Virginia Commonwealth University School of Medicine, Richmond, VA, 23298, USA
    Cost Eff Resour Alloc 10:12. 2012
  3. pmc Could early antiretroviral therapy entail more risks than benefits in sub-Saharan African HIV-infected adults? A model-based analysis
    Xavier Anglaret
    University of Bordeaux, ISPED, Bordeaux, France
    Antivir Ther 18:45-55. 2013
  4. ncbi request reprint [The HIV/AIDS epidemic in sub-Saharan Africa]
    Xavier Anglaret
    INSERM U 593, Universite Victor Segalen Bordeaux 2, 146, rue Leo Saignat, 33076 Bordeaux, France
    Med Sci (Paris) 20:593-8. 2004
  5. ncbi request reprint [Severe opportunistic infections in HIV-positive adults in sub-Saharan Africa]
    X Anglaret
    l Unité INSERM 593, Universite Victor Segalen Bordeaux 2, France
    Med Trop (Mars) 66:343-5. 2006
  6. ncbi request reprint Impact of vital status investigation procedures on estimates of survival in cohorts of HIV-infected patients from Sub-Saharan Africa
    Xavier Anglaret
    INSERM U 593, Universite Victor Segalen, Bordeaux, France
    J Acquir Immune Defic Syndr 35:320-3. 2004
  7. ncbi request reprint Prognostic value of cross-sectional anthropometric indices on short-term risk of mortality in human immunodeficiency virus-infected adults in Abidjan, Côte d'Ivoire
    K Castetbon
    INSERM U 330, Universite Victor Segalen Bordeaux 2, 146 rue de Léo Saignat, 33076 Bordeaux Cedex, France
    Am J Epidemiol 154:75-84. 2001
  8. ncbi request reprint Effect of early chemoprophylaxis with co-trimoxazole on nutritional status evolution in HIV-1-infected adults in Abidjan, Côte d'Ivoire
    K Castetbon
    INSERM U.330, , Bordeaux, France
    AIDS 15:869-76. 2001
  9. ncbi request reprint [HIV infection in Africa. Clinical and therapeutical research]
    R Salamon
    Unité INSERM 330, Universite Victor Segalen Bordeaux 2
    Presse Med 29:146-52. 2000
  10. doi request reprint CD4+ T-lymphocytes natural decrease in HAART-naïve HIV-infected adults in Abidjan
    J Duvignac
    INSERM U593, Bordeaux, France
    HIV Clin Trials 9:26-35. 2008

Collaborators

Detail Information

Publications47

  1. pmc Early upper digestive tract side effects of zidovudine with tenofovir plus emtricitabine in West African adults with high CD4 counts
    Eric Ouattara
    Programme PACCI, Abidjan, Côte d Ivoire Univ Bordeaux, ISPED, F 33000 Bordeaux, France
    J Int AIDS Soc 16:18059. 2013
    ..Clinical Trial Number: NCT00495651...
  2. pmc Patient- and population-level health consequences of discontinuing antiretroviral therapy in settings with inadequate HIV treatment availability
    April D Kimmel
    Department of Healthcare Policy and Research, Virginia Commonwealth University School of Medicine, Richmond, VA, 23298, USA
    Cost Eff Resour Alloc 10:12. 2012
    ..abstract:..
  3. pmc Could early antiretroviral therapy entail more risks than benefits in sub-Saharan African HIV-infected adults? A model-based analysis
    Xavier Anglaret
    University of Bordeaux, ISPED, Bordeaux, France
    Antivir Ther 18:45-55. 2013
    ..We investigated the conditions under which starting ART early could entail more risks than benefits for patients with high CD4⁺ T-cell counts...
  4. ncbi request reprint [The HIV/AIDS epidemic in sub-Saharan Africa]
    Xavier Anglaret
    INSERM U 593, Universite Victor Segalen Bordeaux 2, 146, rue Leo Saignat, 33076 Bordeaux, France
    Med Sci (Paris) 20:593-8. 2004
    ..Far from being without effective tools and research tracks to fight against this plague which decimates a continent, one is above all confronted with a deficit of both mobilization and means...
  5. ncbi request reprint [Severe opportunistic infections in HIV-positive adults in sub-Saharan Africa]
    X Anglaret
    l Unité INSERM 593, Universite Victor Segalen Bordeaux 2, France
    Med Trop (Mars) 66:343-5. 2006
    ..The question of whether antiretroviral treatment should also be initiated "earlier" in sub-Saharan Africa than in Europe has also been raised...
  6. ncbi request reprint Impact of vital status investigation procedures on estimates of survival in cohorts of HIV-infected patients from Sub-Saharan Africa
    Xavier Anglaret
    INSERM U 593, Universite Victor Segalen, Bordeaux, France
    J Acquir Immune Defic Syndr 35:320-3. 2004
    ..We suggest that the percentage of deaths known through VSIPs would be a useful indicator to be added when reporting survival data from urban HIV cohort studies in sub-Saharan Africa...
  7. ncbi request reprint Prognostic value of cross-sectional anthropometric indices on short-term risk of mortality in human immunodeficiency virus-infected adults in Abidjan, Côte d'Ivoire
    K Castetbon
    INSERM U 330, Universite Victor Segalen Bordeaux 2, 146 rue de Léo Saignat, 33076 Bordeaux Cedex, France
    Am J Epidemiol 154:75-84. 2001
    ..In Côte d'Ivoire where chemoprophylaxis of opportunistic infections has recently been recommended to be widely initiated on clinical criteria, such thresholds may help to screen patients with higher risks of mortality...
  8. ncbi request reprint Effect of early chemoprophylaxis with co-trimoxazole on nutritional status evolution in HIV-1-infected adults in Abidjan, Côte d'Ivoire
    K Castetbon
    INSERM U.330, , Bordeaux, France
    AIDS 15:869-76. 2001
    ....
  9. ncbi request reprint [HIV infection in Africa. Clinical and therapeutical research]
    R Salamon
    Unité INSERM 330, Universite Victor Segalen Bordeaux 2
    Presse Med 29:146-52. 2000
    ..To illustrate advances and gaps in HIV/AIDS clinical research in Africa, we explored three issues relevant to this research: opportunistic infections in adults, mother-to-child transmission of HIV and the ethical questions...
  10. doi request reprint CD4+ T-lymphocytes natural decrease in HAART-naïve HIV-infected adults in Abidjan
    J Duvignac
    INSERM U593, Bordeaux, France
    HIV Clin Trials 9:26-35. 2008
    ..To study the CD4 natural decrease and its determinants in sub-Saharan African HIV-infected adults...
  11. pmc Scaling up antiretroviral therapy in South Africa: the impact of speed on survival
    Rochelle P Walensky
    The Divisions of Infectious Disease, Department of Medicine, Massachusetts General Hospital, Boston, MA 02114, USA
    J Infect Dis 197:1324-32. 2008
    ..Only 33% of eligible human immunodeficiency virus (HIV)-infected patients in South Africa receive antiretroviral therapy (ART). We sought to estimate the impact of alternative ART scale-up scenarios on patient outcomes from 2007-2012...
  12. doi request reprint HIV-1 DNA in peripheral blood mononuclear cells is strongly associated with HIV-1 disease progression in recently infected West African adults
    Albert K Minga
    Programme PAC CI, Abidjan, Cote d Ivoire, France
    J Acquir Immune Defic Syndr 48:350-4. 2008
    ..To analyze the association between the HIV-1 DNA level in peripheral blood mononuclear cells (PBMCs) and disease progression in recently infected West African adults...
  13. pmc The independent effect of highly active antiretroviral therapy on severe opportunistic disease incidence and mortality in HIV-infected adults in Côte d'Ivoire
    Elena Losina
    Department of Biostatistics and Epidemiology, Boston University School of Public Health, Boston, MA, USA
    Antivir Ther 12:543-51. 2007
    ..Studies in developed countries have shown highly active antiretroviral therapy (HAART) decreases incidence of severe opportunistic diseases (ODs) in HIV-infected patients beyond that which is expected from changes in CD4+ T-cell count...
  14. doi request reprint Morbidity before and after HAART initiation in Sub-Saharan African HIV-infected adults: a recurrent event analysis
    Catherine Seyler
    Programme PAC CI, Abidjan, Cote d Ivoire
    AIDS Res Hum Retroviruses 23:1338-47. 2007
    ..In HIV-infected patients on ART, the incidence of severe morbidity varied with the past history of morbidity. The past history of morbidity should be taken into account when comparing HIV morbidity rates before and after ART initiation...
  15. ncbi request reprint Cost-effectiveness of HIV treatment in resource-poor settings--the case of Côte d'Ivoire
    Sue J Goldie
    Department of Health Policy and Management, Program in Health Decision Science, Harvard School of Public Health, Boston, MA 02115, USA
    N Engl J Med 355:1141-53. 2006
    ..As antiretroviral therapy is increasingly used in settings with limited resources, key questions about the timing of treatment and use of diagnostic tests to guide clinical decisions must be addressed...
  16. doi request reprint Prophylaxis with co-trimoxazole for HIV infected adults in Africa
    Xavier Anglaret
    BMJ 337:a304. 2008
  17. ncbi request reprint Incidence of neutropenia in HIV-infected African adults receiving co-trimoxazole prophylaxis: a 6-year cohort study in Abidjan, Côte d'Ivoire
    Siaka Toure
    Inserm Unité 593, Universite Victor Segalen Bordeaux 2, 146 rue Leo Saignat, 33076 Bordeaux Cedex, France
    Trans R Soc Trop Med Hyg 100:785-90. 2006
    ..The consequences of associating co-trimoxazole with other haematotoxic drugs should be carefully assessed...
  18. ncbi request reprint Nonantiretroviral drug consumption by CD4 cell count in HIV-infected adults: a 5-year cohort study in Côte d'Ivoire
    Nohelly Nombela
    Unité INSERM U 593, Universite Victor Segalen, Bordeaux, Cedex, France
    J Acquir Immune Defic Syndr 41:225-31. 2006
    ..Meanwhile, they roughly suggest that successful antiretroviral treatment, which would stabilize the CD4 count above 500 cells/mm, could reduce by 5-fold the cost of nonantiretroviral drugs in HIV-infected adults in Abidjan...
  19. ncbi request reprint Medium-term survival, morbidity and immunovirological evolution in HIV-infected adults receiving antiretroviral therapy, Abidjan, Côte d'Ivoire
    Catherine Seyler
    Programme PAC CI, Abidjan, Cote d Ivoire
    Antivir Ther 8:385-93. 2003
    ..To evaluate survival, morbidity, and CD4 and viral load (VL) evolution in HIV-infected adults receiving antiretroviral therapy (ART) in Côte d'Ivoire...
  20. ncbi request reprint Use of a Bayesian approach to decide when to stop a therapeutic trial: the case of a chemoprophylaxis trial in human immunodeficiency virus infection
    Alphonse Kpozehouen
    INSERM U 593, Universite Victor Segalen Bordeaux 2, 146 rue Leo Saignat, 33076 Bordeaux Cedex, France
    Am J Epidemiol 161:595-603. 2005
    ....
  21. ncbi request reprint Risk factors for active tuberculosis after antiretroviral treatment initiation in Abidjan
    Catherine Seyler
    INSERM U593, Universite Victor Segalen Bordeaux 2, 146 rue Leo Saignat, 33076 Bordeaux, France
    Am J Respir Crit Care Med 172:123-7. 2005
    ....
  22. ncbi request reprint Pattern of bacterial diseases in a cohort of HIV-1 infected adults receiving cotrimoxazole prophylaxis in Abidjan, Côte d'Ivoire
    Xavier Anglaret
    INSERM U330, Universite Victor Segalen, Bordeaux, France
    AIDS 17:575-84. 2003
    ..WHO/UNAIDS recommended that cotrimoxazole should be prescribed in Africa in HIV-infected adults with CD4 cell counts < 500 x 10 /l, while closely monitoring bacterial diseases in as many settings as possible...
  23. ncbi request reprint Causes and empirical treatment of fever in HIV-infected adult outpatients, Abidjan, Côte d'Ivoire
    Xavier Anglaret
    INSERM U 330, Universite Victor Segalen Bordeaux, France
    AIDS 16:909-18. 2002
    ..In Abidjan, HIV prevalence has been estimated at 20% in outpatients attending community clinics. Documenting causes of fever in HIV-infected adult outpatients may help to improve care in these centres with limited facilities...
  24. ncbi request reprint Haematological changes in adults receiving a zidovudine-containing HAART regimen in combination with cotrimoxazole in Côte d'Ivoire
    Raoul Moh
    Programme PAC CI, Abidjan, Cote d Ivoire
    Antivir Ther 10:615-24. 2005
    ..We estimated the incidence of haematological disorders during the first 6 months of a zidovudine-containing highly active antiretroviral therapy (HAART) regimen in sub-Saharan African adults receiving cotrimoxazole...
  25. ncbi request reprint Incidence and determinants of mortality and morbidity following early antiretroviral therapy initiation in HIV-infected adults in West Africa
    Raoul Moh
    Trivacan ANRS 1269 study group, Abidjan, France
    AIDS 21:2483-91. 2007
    ..To estimate the incidence and risk factors of mortality and severe morbidity during the first months following antiretroviral therapy (ART) initiation in West African adults...
  26. ncbi request reprint Variation of CD4 count and percentage during pregnancy and after delivery: implications for HAART initiation in resource-limited settings
    Didier K Ekouevi
    Programme PACCI, Abidjan, Cote d Ivoire, INSERM, Unité 593, Bordeaux, France
    AIDS Res Hum Retroviruses 23:1469-74. 2007
    ..To accurately target the most appropriate time to start HAART, the CD4 percentage could be more reliable than the absolute count in sub-Saharan African pregnant women...
  27. ncbi request reprint Decreasing incidence of pregnancy by decreasing CD4 cell count in HIV-infected women in Côte d'Ivoire: a 7-year cohort study
    Marc Arthur Loko
    INSERM U 593, Universite Victor Segalen, Bordeaux 2, Bordeaux, France
    AIDS 19:443-5. 2005
    ..This has consequences in terms of scaling-up strategies for highly active antiretroviral therapy (HAART). Women who need HAART will be less likely than those who do not to be recruited into prenatal care facilities...
  28. ncbi request reprint Urinary pH in HIV-infected adults in Ivory Coast and in France
    Emmanuel Mortier
    AIDS 17:2003-5. 2003
  29. ncbi request reprint High incidence of atypical mycobacteriosis in African HIV-infected adults with low CD4 cell counts: a 6-year cohort study in Côte d'Ivoire
    Dominique Bonard
    Programme PAC CI, Abidjan, Cote d Ivoire, France
    AIDS 18:1961-4. 2004
    ..In sub-Saharan Africa, where most patients start highly active antiretroviral therapy with low CD4 cell counts, improving the diagnosis of NTM may be relevant...
  30. ncbi request reprint Rapid scaling-up of antiretroviral therapy in 10,000 adults in Côte d'Ivoire: 2-year outcomes and determinants
    Siaka Toure
    Aconda Association, Abidjan, Cote d Ivoire
    AIDS 22:873-82. 2008
    ..To assess the rates and determinants of mortality, loss to follow-up and immunological failure in a nongovernmental organization-implemented program of access to antiretroviral treatment in Côte d'Ivoire...
  31. ncbi request reprint Tolerance and acceptability of an efavirenz-based regimen in 740 adults (predominantly women) in West Africa
    Christine Danel
    Programme PAC CI, Abidjan, Cote d Ivoire, France
    J Acquir Immune Defic Syndr 42:29-35. 2006
    ....
  32. pmc Early loss of HIV-infected patients on potent antiretroviral therapy programmes in lower-income countries
    Martin W G Brinkhof
    Institute of Social and Preventive Medicine, Bern, Switzerland
    Bull World Health Organ 86:559-67. 2008
    ..To analyse the early loss of patients to antiretroviral therapy (ART) programmes in resource-limited settings...
  33. ncbi request reprint HIV-1 antiretroviral drug resistance in recently infected patients in Abidjan, Côte d'Ivoire: A 4-year survey, 2002-2006
    Bernard Masquelier
    Programme PAC CI Primo CI ANRS 1220, Abidjan, Cote d Ivoire
    AIDS Res Hum Retroviruses 23:1155-60. 2007
    ..Compared with a previous study carried out by our group in 2001-2002 in a similar population in Abidjan, our findings confirm the circulation and transmission of HIV-1 carrying key ARV drug resistance mutation...
  34. pmc Estimates of opportunistic infection incidence or death within specific CD4 strata in HIV-infected patients in Abidjan, Côte d'Ivoire: impact of alternative methods of CD4 count modelling
    Sylvie Deuffic-Burban
    CTRS, Unité INSERM 795, Hôpital Swynghedauw, CHRU de Lille, Lille, France
    Eur J Epidemiol 22:737-44. 2007
    ..All of the models indicate that the overall incidence of opportunistic infections under HAART in sub-Saharan Africa is high. This suggests that prophylaxis against opportunistic infections may be needed even for patients receiving HAART...
  35. ncbi request reprint CD4-guided structured antiretroviral treatment interruption strategy in HIV-infected adults in west Africa (Trivacan ANRS 1269 trial): a randomised trial
    Christine Danel
    Programme PAC CI, Abidjan, Cote d Ivoire
    Lancet 367:1981-9. 2006
    ..We did a randomised trial of structured treatment interruption in Abidjan, Côte d'Ivoire...
  36. ncbi request reprint Risk factors for active tuberculosis in adults on highly active antiretroviral therapy in Africa
    Catherine Seyler
    AIDS 20:1463; author reply 1463-5. 2006
  37. ncbi request reprint Commentary: decline of HIV-2 prevalence in West Africa: good news or bad news?
    Serge Eholie
    Service des maladies infectieuses et tropicales CHU de Treichville, Abidjan, Cote d Ivoire
    Int J Epidemiol 35:1329-30. 2006
  38. ncbi request reprint Clinical impact and cost-effectiveness of co-trimoxazole prophylaxis in patients with HIV/AIDS in Côte d'Ivoire: a trial-based analysis
    Yazdan Yazdanpanah
    Service Universitaire des Maladies Infectieuses et du Voyageur, Centre Hospitalier de Tourcoing, Faculte de Medecine de Lille, France
    AIDS 19:1299-308. 2005
    ..In 2000, WHO/UNAIDS recommended co-trimoxazole prophylaxis for persons at early stages of HIV infection (WHO stage > or = 2) in sub-Saharan Africa...
  39. pmc Transfer and evaluation of an automated, low-cost real-time reverse transcription-PCR test for diagnosis and monitoring of human immunodeficiency virus type 1 infection in a West African resource-limited setting
    Francois Rouet
    Centre de Diagnostic et de Recherches sur le SIDA, Abidjan, Cote d Ivoire
    J Clin Microbiol 43:2709-17. 2005
    ..The TaqMan real-time PCR (12 dollars per test) is now routinely used to monitor HIV-1 infection in our laboratory. This technology should be further evaluated in limited-resource countries where strains other than CRF02 are prevalent...
  40. ncbi request reprint Stability of ritonavir soft capsule formulation in patients with and without a refrigerator at home in Côte d'Ivoire
    Christine Danel
    Int J STD AIDS 17:784-5. 2006
  41. ncbi request reprint Are a past history of tuberculosis and WHO clinical stage associated with incident tuberculosis in adults receiving antiretroviral therapy?, reply to Lawn et al
    Eric Ouattara
    AIDS 21:389-90. 2007
  42. pmc Lack of indinavir-associated nephrological complications in HIV-infected adults (predominantly women) with high indinavir plasma concentration in Abidjan, Côte d'Ivoire
    Christine Danel
    Programme PAC CI, Abidjan, Ccte d Ivoire
    AIDS Res Hum Retroviruses 23:62-6. 2007
    ..There was a surprising lack of nephrological side effects during the 6 months of follow-up, supporting the hypothesis that nephrological tolerance of IDV might be higher in sub-Saharan African individuals than in Americans or Europeans...
  43. pmc Progression to WHO criteria for antiretroviral therapy in a 7-year cohort of adult HIV-1 seroconverters in Abidjan, Côte d'Ivoire
    Albert Minga
    Programme PAC CI, Abidjan, Cote d Ivoire
    Bull World Health Organ 85:116-23. 2007
    ..To estimate the probability of reaching the criteria for starting highly active antiretroviral therapy (HAART) in a prospective cohort of adult HIV-1 seroconverters in Abidjan, Côte d'Ivoire...
  44. ncbi request reprint Field adherence to highly active antiretroviral therapy in HIV-infected adults in Abidjan, Côte d'Ivoire
    Serge Paul Eholie
    Service des Maladies Infectieuses et Tropicales, Centre Hospitalier Universitaire de Treichville, Abidjan, Cote d Ivoire
    J Acquir Immune Defic Syndr 45:355-8. 2007
    ..To estimate adherence to highly active antiretroviral therapy (HAART) and its determinants in HIV-infected adults followed in field conditions in Abidjan...
  45. pmc HIV drug resistance surveillance for prioritizing treatment in resource-limited settings
    Rochelle P Walensky
    Division of Infectious Disease, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    AIDS 21:973-82. 2007
    ..Sentinel testing programs for HIV drug resistance in resource-limited settings can inform policy on antiretroviral therapy (ART) and drug sequencing...
  46. pmc Impact of genotypic drug resistance mutations on clinical and immunological outcomes in HIV-infected adults on HAART in West Africa
    Catherine Seyler
    INSERM U593, Universite Victor Segalen Bordeaux 2, 146 rue Leo Saignat, 33076 Bordeaux, France
    AIDS 21:1157-64. 2007
    ..To analyse the association between the presence of resistance mutations and treatment outcomes. The impact of HIV-1 drug resistance mutations in African adults on HAART has so far never been reported...
  47. pmc Anthropometric and immunological success of antiretroviral therapy and prediction of virological success in west African adults
    Eugene Messou
    Programme PAC, CI, Abidjan, Cote d Ivoire
    Bull World Health Organ 86:435-42. 2008
    ..We assessed the gain or loss in body mass index (BMI), alone or in combination with the gain or loss in CD4+ T-cell count (CD4), as a tool for predicting the response to ART...