E Andres

Summary

Country: France

Publications

  1. doi request reprint [National exam for the validation of the second medicine cycle in France: What does this examination evaluates?]
    Emmanuel Andres
    CHRU de Strasbourg, Hopital Civil, clinique médicale B, Service de Medecine Interne, 67091 Strasbourg Cedex, France
    Presse Med 41:e245-9. 2012
  2. doi request reprint Anemia in elderly patients: new insight into an old disorder
    Emmanuel Andres
    Department of Internal Medicine, Diabetes and Metabolic Disorders, University Hospital of Strasbourg, Strasbourg, France
    Geriatr Gerontol Int 13:519-27. 2013
  3. doi request reprint The pathophysiology of elevated vitamin B12 in clinical practice
    E Andres
    Service de Medecine Interne, diabète et maladies métaboliques, clinique médicale B, Hopital Civil, Hopitaux Universitaires de Strasbourg, 1 Porte de l Hôpital, 67091 Strasbourg Cedex, France
    QJM 106:505-15. 2013
  4. doi request reprint [Metabolic impact of androgen deprivation therapy for prostate cancer]
    E Andres
    Service Medecine Interne, diabète et maladies métaboliques, clinique médicale B, CHRU Strasbourg, Strasbourg, F 67000, France
    Prog Urol 22:S39-47. 2012
  5. doi request reprint Gender-related analysis of the clinical presentation, treatment response and outcome in patients with immune thrombocytopenia
    Emmanuel Andres
    University Hospital of Strasbourg, Department of Internal Medicine B, 67091 Strasbourg Cedex, France
    Presse Med 41:e426-31. 2012
  6. doi request reprint Cationic antimicrobial peptides in clinical development, with special focus on thanatin and heliomicin
    E Andres
    Service de Medecine Interne, clinique médicale B, Hopitaux Universitaires de Strasbourg, Strasbourg, France
    Eur J Clin Microbiol Infect Dis 31:881-8. 2012
  7. ncbi request reprint Food-cobalamin malabsorption in elderly patients: clinical manifestations and treatment
    Emmanuel Andres
    Department of Internal Medicine, Diabetes and Metabolic Disorders, Hopitaux Universitaires de Strasbourg, Strasbourg, France
    Am J Med 118:1154-9. 2005
  8. ncbi request reprint Hematological response to short-term oral cyanocobalamin therapy for the treatment of cobalamin deficiencies in elderly patients
    E Andres
    Department of Internal Medicine, Hopitaux Universitaires de Strasbourg, 67 091 Strasbourg Cedex, France
    J Nutr Health Aging 10:3-6. 2006
  9. ncbi request reprint Pseudo-thrombotic microangiopathy related to cobalamin deficiency
    Emmanuel Andres
    Department of Internal Medicine, Diabetes and Metabolic Disorders, Hopitaux Universitaires de Strasbourg, Strasbourg, France
    Am J Med 119:e3. 2006
  10. ncbi request reprint [Idiosyncratic drug-induced agranulocytosis]
    E Andres
    Service de Medecine Interne, clinique médicale B, Hopitaux Universitaires de Strasbourg, France
    Rev Med Interne 27:209-14. 2006

Collaborators

Detail Information

Publications82

  1. doi request reprint [National exam for the validation of the second medicine cycle in France: What does this examination evaluates?]
    Emmanuel Andres
    CHRU de Strasbourg, Hopital Civil, clinique médicale B, Service de Medecine Interne, 67091 Strasbourg Cedex, France
    Presse Med 41:e245-9. 2012
    ..Since 2004, the national exam for the validation of the second medicine cycle in France has been changed in its organization, its form and contents. The objective of this study is to analyze the records and the contents of this exam...
  2. doi request reprint Anemia in elderly patients: new insight into an old disorder
    Emmanuel Andres
    Department of Internal Medicine, Diabetes and Metabolic Disorders, University Hospital of Strasbourg, Strasbourg, France
    Geriatr Gerontol Int 13:519-27. 2013
    ..Nevertheless, most cases of anemia require further investigation and the underlying cause should be identified and treated whenever possible...
  3. doi request reprint The pathophysiology of elevated vitamin B12 in clinical practice
    E Andres
    Service de Medecine Interne, diabète et maladies métaboliques, clinique médicale B, Hopital Civil, Hopitaux Universitaires de Strasbourg, 1 Porte de l Hôpital, 67091 Strasbourg Cedex, France
    QJM 106:505-15. 2013
    ..Functional cobalamin deficiency can thus occur at any serum level...
  4. doi request reprint [Metabolic impact of androgen deprivation therapy for prostate cancer]
    E Andres
    Service Medecine Interne, diabète et maladies métaboliques, clinique médicale B, CHRU Strasbourg, Strasbourg, F 67000, France
    Prog Urol 22:S39-47. 2012
    ....
  5. doi request reprint Gender-related analysis of the clinical presentation, treatment response and outcome in patients with immune thrombocytopenia
    Emmanuel Andres
    University Hospital of Strasbourg, Department of Internal Medicine B, 67091 Strasbourg Cedex, France
    Presse Med 41:e426-31. 2012
    ..In this paper, we report a gender-related analysis of patients with ITP, specifically examining the clinical manifestations, responses to treatment and overall outcomes of the patients...
  6. doi request reprint Cationic antimicrobial peptides in clinical development, with special focus on thanatin and heliomicin
    E Andres
    Service de Medecine Interne, clinique médicale B, Hopitaux Universitaires de Strasbourg, Strasbourg, France
    Eur J Clin Microbiol Infect Dis 31:881-8. 2012
    ..Aspergillus sp., Candida sp. etc.) and may represent important additions to the anti-infectious therapeutic arsenal...
  7. ncbi request reprint Food-cobalamin malabsorption in elderly patients: clinical manifestations and treatment
    Emmanuel Andres
    Department of Internal Medicine, Diabetes and Metabolic Disorders, Hopitaux Universitaires de Strasbourg, Strasbourg, France
    Am J Med 118:1154-9. 2005
    ..To date, no study has documented this disorder in the elderly. There is also little information on clinical consequences...
  8. ncbi request reprint Hematological response to short-term oral cyanocobalamin therapy for the treatment of cobalamin deficiencies in elderly patients
    E Andres
    Department of Internal Medicine, Hopitaux Universitaires de Strasbourg, 67 091 Strasbourg Cedex, France
    J Nutr Health Aging 10:3-6. 2006
    ..The aim of this trial was to demonstrate the efficacy of one month of oral cobalamin (vitamin B12) therapy in elderly patients with cobalamin deficiency related to food-cobalamin malabsorption (FCM)...
  9. ncbi request reprint Pseudo-thrombotic microangiopathy related to cobalamin deficiency
    Emmanuel Andres
    Department of Internal Medicine, Diabetes and Metabolic Disorders, Hopitaux Universitaires de Strasbourg, Strasbourg, France
    Am J Med 119:e3. 2006
  10. ncbi request reprint [Idiosyncratic drug-induced agranulocytosis]
    E Andres
    Service de Medecine Interne, clinique médicale B, Hopitaux Universitaires de Strasbourg, France
    Rev Med Interne 27:209-14. 2006
    ..Agranulocytosis is a life-threatening disorder that frequently occurs as an adverse reaction to drugs...
  11. ncbi request reprint [Cobalamin deficiencies in adults: update of etiologies, clinical manifestations and treatment]
    E Andres
    Service de Medecine Interne, diabète et maladies métaboliques de la clinique médicale B, Hopitaux Universitaires de Strasbourg, France
    Rev Med Interne 26:938-46. 2005
    ..Update of the adult cobalamin deficiencies...
  12. ncbi request reprint [Acute pulmonary embolism related to pulmonary giant cell arteritis]
    Emmanuel Andres
    Service de Medecine Interne, Hopital de Hautepierre, Hôpitaux Universitaires de Strasbourg 67
    Presse Med 33:1328-9. 2004
    ..We report a case of giant cell pulmonary arteritis revealed by acute pulmonary embolism and associated with giant cell arteritis...
  13. ncbi request reprint [Cationic anti-microbial peptides: from innate immunity study to drug development]
    E Andres
    UPR 9022 du CNRS, Institut de Biologie Moleculaire et Cellulaire, 15, rue René Descartes, 67000 Strasbourg, France
    Rev Med Interne 25:629-35. 2004
    ..Host defense, cationic anti-microbial peptides are recognized as an important component of innate immune response in most multicellular organisms...
  14. pmc Vitamin B12 (cobalamin) deficiency in elderly patients
    Emmanuel Andres
    Department of Internal Medicine, Medical Clinic B, Strasbourg University Hospitals, Strasbourg, France
    CMAJ 171:251-9. 2004
    ..We review the epidemiology and causes of cobalamin deficiency in elderly people, with an emphasis on food-cobalamin malabsorption syndrome. We also review diagnostic and management strategies for cobalamin deficiency...
  15. ncbi request reprint [Is there a link between the food-cobalamin malabsorption and the pernicious anemia?]
    E Andres
    Service de Medecine Interne, Hopitaux Universitaires de Strasbourg, 1 Porte de l Hôpital, 67091 Strasbourg Cedex, France
    Ann Endocrinol (Paris) 65:118-20. 2004
    ..A relation between food-cobalamin malabsorption and pernicious anemia has been suggested, particularly in the event of food-cobalamin malabsorption related to hypochlorhydric atrophic gastritis...
  16. ncbi request reprint [Cationic antimicrobial peptides: from innate immunity study to drug development. Up date]
    E Andres
    Service de Medecine Interne, clinique médicale B, Hopitaux Universitaires de Strasbourg, France
    Med Mal Infect 37:194-9. 2007
    ..Host defense, cationic anti-microbial peptides are recognized as an important component of innate immune response in most multicellular organisms...
  17. ncbi request reprint B12 deficiency: a look beyond pernicious anemia
    Emmanuel Andres
    Department of Internal Medicine, Diabetes and Metabolic Diseases, Hopitaux Universitaires de Strasbourg, Strasbourg, France
    J Fam Pract 56:537-42. 2007
  18. doi request reprint Clinical presentation and management of drug-induced agranulocytosis
    Emmanuel Andres
    Department of Internal Medicine B, University Hospital of Strasbourg, 1 Porte de l Hôpital, Strasbourg Cedex, France
    Expert Rev Hematol 4:143-51. 2011
    ..In this article, we report and discuss the clinical presentation and management of idiosyncratic drug-induced agranulocytosis (neutrophil count <0.5 × 10(9)/l)...
  19. doi request reprint The role of haematopoietic growth factors granulocyte colony-stimulating factor and granulocyte-macrophage colony-stimulating factor in the management of drug-induced agranulocytosis
    Emmanuel Andres
    Department of Internal Medicine, B Clinic, University Hospital of Strasbourg, Strasbourg, France
    Br J Haematol 150:3-8. 2010
    ..In all cases, the drug responsible for causing the agranulocytosis must be discontinued and remain permanently contraindicated. The appropriate Medicines Regulatory Agency must also be notified of the adverse event...
  20. doi request reprint Efficacy of oral cobalamin (vitamin B12) therapy
    Emmanuel Andres
    Hôpital Civil Hôpitaux Universitaires de Strasbourg, Department of Internal Medicine, Diabetes and Metabolic Diseases, clinique médicale B, 1 Porte de l Hôpital, 67091 Strasbourg Cedex, France
    Expert Opin Pharmacother 11:249-56. 2010
    ..Management of cobalamin deficiency with cobalamin injections is well codified at present, but new routes of cobalamin administration (oral and nasal) are being studied, especially oral cobalamin therapy for food-cobalamin malabsorption...
  21. doi request reprint Update of nutrient-deficiency anemia in elderly patients
    Emmanuel Andres
    Department of Internal Medicine, University Hospital of Strasbourg, Strasbourg, France
    Eur J Intern Med 19:488-93. 2008
    ..The remaining cases of nutrient-deficiency anemia are usually associated with vitamin B12, most frequently related to food-cobalamin malabsorption, and/or folate deficiency and are easily treated (nutrient-deficiency replacement)...
  22. doi request reprint [Update of oral vitamin B12]
    E Andres
    Service de Medecine Interne, diabète et maladies métaboliques, clinique médicale B, Hopital Civil, Hopitaux Universitaires de Strasbourg, 67091 Strasbourg Cedex, France
    Ann Endocrinol (Paris) 70:455-61. 2009
    ..The objective of this review is to evaluate the usefulness of oral cobalamin (vitamin B12) treatment...
  23. ncbi request reprint Recognition and management of drug-induced cytopenias: the example of idiosyncratic drug-induced thrombocytopenia
    Emmanuel Andres
    Service de Medecine Interne, diabète et maladies métaboliques, clinique médicale B, Hôpital Civil Hôpitaux Universitaires de Strasbourg, Strasbourg Cedex, France
    Expert Opin Drug Saf 8:183-90. 2009
    ..Several hundred drugs, toxins and herbs have been reported to cause blood abnormalities, and drugs account for 20 - 40% of all instances of cytopenias...
  24. doi request reprint Update on oral cyanocobalamin (vitamin B12) treatment in elderly patients
    Emmanuel Andres
    Department of Internal Medicine, Diabetes and Metabolic Diseases, Hopitaux Universitaires de Strasbourg, Strasbourg, France
    Drugs Aging 25:927-32. 2008
    ..This review confirms the previously reported efficacy of oral cobalamin treatment in elderly patients. Oral cobalamin treatment avoids the discomfort, inconvenience and cost of monthly injections...
  25. ncbi request reprint Recognition and management of drug-induced blood cytopenias: the example of drug-induced acute neutropenia and agranulocytosis
    Emmanuel Andres
    Hopitaux Universitaires de Strasbourg, Service de Medecine Interne, clinique médicale B, Hopital Civil, 1 Porte de l Hôpital, 67 091 Strasbourg Cedex, France
    Expert Opin Drug Saf 7:481-9. 2008
    ..More than several hundred drugs, toxins, and herbs have been reported to cause blood abnormalities, and drugs account for 20 - 40% of all instances of cytopenias...
  26. ncbi request reprint Idiosyncratic drug-induced agranulocytosis or acute neutropenia
    Emmanuel Andres
    Department of Internal Medicine, University Hospital of Strasbourg, 1 Porte de l Hôpital, 67 091 Strasbourg Cedex, France
    Curr Opin Hematol 15:15-21. 2008
    ..5 x 10/l. Patients with such severe neutropenia are likely to experience life-threatening and sometimes fatal infections...
  27. ncbi request reprint Life-threatening idiosyncratic drug-induced agranulocytosis in elderly patients
    Emmanuel Andres
    Department of Internal Medicine, Hôpitaux Universitaires of Strasbourg, Strasbourg, France
    Drugs Aging 21:427-35. 2004
    ..However, given the increased life expectancy and subsequent longer exposure to drugs, as well as the development of new agents, physicians should be aware of this complication and its management...
  28. ncbi request reprint Otological manifestations of acute leukaemia: report of two cases and review of literature
    E Andres
    Department of Internal Medicine, Hopitaux Universitaires de Strasbourg, France
    Clin Lab Haematol 23:57-60. 2001
    ..It is suggested that middle and inner ear can be a 'sanctuary' localization, which might sometimes require radiation therapy to achieve durable and complete remission...
  29. ncbi request reprint Primary hepatic anaplastic large cell Ki-1 non-Hodgkin's lymphoma and hereditary hemochromatosis: a fortuitous association?
    E Andres
    Department of Internal Medicine, Hopitaux Universitaires de Strasbourg, France
    Clin Lab Haematol 25:185-6. 2003
    ..We report here a case of primary hepatic anaplastic large cell Ki-1 non-Hodgkin's lymphoma in a 60 year old patient followed for hereditary hemochromatosis...
  30. ncbi request reprint [Splenic thrombosis and celiac disease: a fortuitous association?]
    E Andres
    Service de Medecine interne et nutrition, Hopitaux Universitaires de Strasbourg
    Presse Med 29:1933-4. 2000
    ..Rare cases of venous thrombosis associated with celiac disease have been reported...
  31. ncbi request reprint Retrospective monocentric study of 17 patients with adult Still's disease, with special focus on liver abnormalities
    Emmanuel Andres
    Department of Internal Medicine, Hopitaux Universitaires de Strasbourg, France
    Hepatogastroenterology 50:192-5. 2003
    ..Liver dysfunction in adult Still's disease has been described in some case reports. The objective of this study was to analyze the pattern and the frequency of liver abnormalities in a monocenter series of adult Still's disease patients...
  32. ncbi request reprint Nonchemotherapy drug-induced agranulocytosis: experience of the Strasbourg teaching hospital (1985-2000) and review of the literature
    E Andres
    Department of Internal Medicine, Hôpitaux Universitaires of Strasbourg, France
    Clin Lab Haematol 24:99-106. 2002
    ..DIA still remains a rare event. However, given the increased life expectancy and subsequent longer exposure to drugs, as well as the development of new agents, physicians should be aware of this complication and its management...
  33. ncbi request reprint Iliac bone defects revealing systemic sarcoidosis
    E Andres
    Internal Medicine and Nutrition Department, Hopital de Hautepierre, Strasbourg, France
    Joint Bone Spine 68:74-5. 2001
    ..Computed tomography showed multiple punched-out defects in the left iliac bone. No similar cases have been reported in the literature...
  34. ncbi request reprint [Adult Still's disease: an unrecognized cause of acute febrile hepatic cytolysis. Study of twelve patients]
    E Andres
    Service de Medecine interne et nutrition, Hopitaux Universitaires, Strasbourg, France
    Gastroenterol Clin Biol 25:353-5. 2001
    ..Certain liver test abnormalities have been described in adult Still's disease. The objective of the present study was to analyze their type and frequency...
  35. ncbi request reprint Haematopoietic growth factor in antithyroid-drug-induced agranulocytosis
    E Andres
    Department of Internal Medicine, University of Strasbourg, Strasbourg, France
    QJM 94:423-8. 2001
    ..8+/-4 days vs. 11.6+/-5; 7.5+/-3.8 days vs. 12+/-4.5; and 7.3+/-4.8 days vs. 13+/-6.1, respectively (all p<0.05). G-CSF induced flu-like symptoms in 30% of patients, but reduced overall costs...
  36. ncbi request reprint Efficacy of short-term oral cobalamin therapy for the treatment of cobalamin deficiencies related to food-cobalamin malabsorption: a study of 30 patients
    E Andres
    Department of Internal Medicine, Diabetes and Metabolic Disorders, Hopitaux Universitaires de Strasbourg, France
    Clin Lab Haematol 25:161-6. 2003
    ..It has been suggested that oral cobalamin (vitamin (B12)) therapy may be an effective therapy for treating cobalamin deficiencies related to food-cobalamin malabsorption. However, the duration of this treatment was not determined...
  37. ncbi request reprint [Vitamin B12 deficiency with normal Schilling test or non-dissociation of vitamin B12 and its carrier proteins in elderly patients. A study of 60 patients]
    E Andres
    Services de Médecine Interne, diabète et maladies métaboliques, Hopitaux Universitaires de Strasbourg, clinique médicale B, 1, Place de l Hopital, 67091 Strasbourg Cedex, France
    Rev Med Interne 24:218-23. 2003
    ..But to date, only case reports or small series have been reported. The aim of this study was to describe the clinical characteristics of the FCM in old subjects...
  38. ncbi request reprint Oral cobalamin therapy for the treatment of patients with food-cobalamin malabsorption
    E Andres
    Department of Internal Medicine and Nutrition, Hopital de Hautepierre, Strasbourg, France
    Am J Med 111:126-9. 2001
    ..It has been suggested that oral cobalamin therapy may be effective for treating patients who have food-cobalamin malabsorption...
  39. ncbi request reprint Cobalamin deficiency due to non-immune atrophic gastritis in elderly patients. A report of 25 cases
    N Henoun Loukili
    Department of Internal Medicine, Diabetes and Metabolic Disorders, Hopitaux Universitaires de Strasbourg, France
    J Nutr Health Aging 9:462. 2005
  40. ncbi request reprint Current hematological findings in cobalamin deficiency. A study of 201 consecutive patients with documented cobalamin deficiency
    E Andres
    Department of Internal Medicine, Hopitaux Universitaires de Strasbourg, Strasbourg, France
    Clin Lab Haematol 28:50-6. 2006
    ....
  41. ncbi request reprint Current management of adult idiopathic thrombocytopenic purpura in practice: a cohort study of 201 patients from a single center
    J Zimmer
    Department of Onco Hematology, Hopitaux Universitaires de Strasbourg, Strasbourg, France
    Clin Lab Haematol 26:137-42. 2004
    ..In severe cases, splenectomy is the only treatment giving durable cures in a significant proportion of patients. Despite frequent chronicity, ITP is life-threatening only in a minor subset of patients...
  42. doi request reprint Homocysteine, vitamin B12, folate and cognitive functions: a systematic and critical review of the literature
    T Vogel
    Pôle de gériatrie, Hopitaux Universitaires de Strasbourg, Hôpital de la Robertsau, Pavillon Schutzenberger, Strasbourg Cedex, France
    Int J Clin Pract 63:1061-7. 2009
    ..In this report, we review the current knowledge on the relationship between homocysteine, folate and vitamin B(12) levels and the way their disruption influences cognitive function in adults...
  43. ncbi request reprint [New lipid formulations of amphotericin B. Review of the literature]
    E Andres
    Service de Medecine interne et nutrition, Hopital de Hautepierre, Avenue Moliere, 67098 Strasbourg, France
    Rev Med Interne 22:141-50. 2001
    ..This review analyzes the data available in the literature...
  44. ncbi request reprint [Update of clinical findings in cobalamin deficiency: personal data and review of the literature]
    L Federici
    Service de Medecine Interne, diabète et maladies métaboliques, clinique médicale B, Hopital Civil, Hopitaux Universitaires de Strasbourg, 1, Place de l Hopital, 67091 Strasbourg Cedex, France
    Rev Med Interne 28:225-31. 2007
    ..PROSPECTS AND PROJECTS: Future studies will confirm these data with the routine use of the new cobalamin assay: holotranscobalamin and validate the usefulness of oral cobalamin therapy...
  45. ncbi request reprint [Autoimmune peripheral neuropathies with anti-MAG antibodies and hematological disorders. Five cases]
    E Andres
    Services de Médecine Interne et Nutrition, clinique médicale B, Hopital, 67091 Strasbourg Cedex, France
    Ann Med Interne (Paris) 152:147-51. 2001
    ..The aim of this study was to report our experience with autoimmune neuropathies associated with hematological disorders and to describe their etiological and clinical polymorphism...
  46. ncbi request reprint [A urachus cyst revealing a torpid Crohn's disease in a young adult with chronic fever]
    T Weitten
    Service de Medecine Interne, diabète et maladies métaboliques, Hopitaux Universitaires de Strasbourg
    Presse Med 34:581-2. 2005
    ..This case report describes a rare situation in which a superinfected cyst of the urachus complicated initially unknown and inactive Crohn's disease...
  47. ncbi request reprint [Update of pernicious anemia. A retrospective study of 49 cases]
    N H Loukili
    Service de Medecine Interne, diabète et maladies métaboliques de la clinique médicale B, Hopitaux Universitaires de Strasbourg, 1, Place de l Hopital, 67091 Strasbourg, France
    Rev Med Interne 25:556-61. 2004
    ..The aim of this study was to describe the present clinical characteristics of the pernicious anemia (PA)...
  48. ncbi request reprint [Capillary hyperpermeability syndrome of the face]
    E Andres
    Service de Medecine interne et nutrition, Hopitaux Universitaires de Strasbourg
    Presse Med 29:1279-81. 2000
    ..Capillary leak syndrome is a rare disorder, with various clinical features, characterized by episodes of diffuse edema...
  49. doi request reprint Value of (18)F-FDG-PET/CT in patients with fever of unknown origin and unexplained prolonged inflammatory syndrome: a single centre analysis experience
    L Federici
    Department of Internal Medicine, Medical Clinic B, University Hospital of Strasbourg, Strasbourg, France
    Int J Clin Pract 64:55-60. 2010
    ....
  50. doi request reprint Oral cobalamin (vitamin B(12)) treatment. An update
    E Andres
    Department of Internal Medicine, Diabetes and Metabolic Diseases, Hopitaux Universitaires de Strasbourg, Strasbourg, France
    Int J Lab Hematol 31:1-8. 2009
    ..This present review confirms the previously reported efficacy of oral cobalamin treatment in adult and elderly patients...
  51. doi request reprint [Acute, hyperintense, and febrile cervicalgia. Crowned dens syndrome, a monofocal microcrystalline arthritis sometimes doubly misleading]
    T Weitten
    Service de Medecine Interne, clinique médicale B, CHRU de Strasbourg, porte de l Hôpital, Strasbourg, France
    Med Mal Infect 40:363-5. 2010
    ..Indeed, calcifications may be very discrete or just incidental and prevent a complete diagnostic approach...
  52. ncbi request reprint [Failure of bone marrow autograft in metastatic malignant adrenalcortical carcinoma]
    E Andres
    Service de Medecine interne et nutrition, Hopital de Hautepierre, Strasbourg
    Ann Endocrinol (Paris) 61:192-3. 2000
    ..Despite different therapeutic modalities (surgery, hormones therapy, chemotherapy), 5-year survival in patients with malignant adrenocortical carcinoma remains only 10% to 20%. Bone marrow grafts may be proposed to intensify treatment...
  53. ncbi request reprint Nonchemotherapy drug-induced agranulocytosis in elderly patients: the effects of granulocyte colony-stimulating factor
    Emmanuel Andres
    Department of Internal Medicine, Hôpitaux Universitaires of Strasbourg, Strasbourg, France
    Am J Med 112:460-4. 2002
    ..We studied whether granulocyte colony-stimulating factor (G-CSF), a hematopoietic growth factor that shortens the duration of neutropenia, is useful in these patients...
  54. doi request reprint Prevalence, characteristics and prognostic significance of anemia in daily practice
    B Terrier
    Department of Internal Medicine, APHP Groupe Hospitalier Pitié Salpé trière, Universite Pierre et Marie Curie, Paris 6, Paris, France
    QJM 105:345-54. 2012
    ..The prevalence of anemia has been studied in well-defined populations, but no large study is available for less restricted populations with various disorders...
  55. ncbi request reprint Efficacy of amphotericin B lipid complex in the treatment of invasive fungal infections in immunosuppressed paediatric patients
    R Herbrecht
    Département d Hématologie et d Oncologie, H pital de Hautepierre, Strasbourg, France
    Eur J Clin Microbiol Infect Dis 20:77-82. 2001
    ..2 micromol/l at the end of therapy. These results support the use of ABLC in the treatment of invasive fungal infections in children, including patients who have previously failed, or are intolerant of, traditional antifungal regimens...
  56. ncbi request reprint [Drug-induced agranulocytosis in rheumatology. A retrospective study of 12 cases]
    K Serraj
    Service de Medecine Interne, diabète et maladies métaboliques, clinique médicale B, CHRU de Strasbourg
    Ann Biol Clin (Paris) 65:431-6. 2007
    ..the aim of this study is to determine the clinical characteristics of drug-induced agranulocytosis in rheumatology...
  57. doi request reprint [A not so common "community" acquired pneumonia]
    E Ciobanu
    Service de Medecine Interne, diabète et maladies métaboliques, clinique médicale B, Hopital Civil, Hopitaux Universitaires de Strasbourg, 1, porte de l Hôpital, 67091 Strasbourg Cedex, France
    Med Mal Infect 40:391-2, 421-4. 2010
    ..We report the case of a 50-year-old male patient, with a peculiar initial clinical presentation mimicking acute community acquired pneumonia but with an atypical evolution leading to a final diagnosis of actinomycosis...
  58. doi request reprint An update on cobalamin deficiency in adults
    N Dali-Youcef
    Service de Medecine Interne, diabète et maladies métaboliques, clinique médicale B, Hôpital Civil Hôpitaux Universitaires de Strasbourg, 1 Porte de l Hôpital, 67091 Strasbourg Cedex, France
    QJM 102:17-28. 2009
    ..Management of cobalamin deficiency with cobalamin injections is currently well codified, but new routes of cobalamin administration (oral and nasal) are being studied, especially oral cobalamin therapy for food-cobalamin malabsorption...
  59. ncbi request reprint [Vitamin B12 in the adult: of metabolism and deficiencies]
    N Henoun Loukili
    Service de Medecine Interne, Diabète et Maladies Métaboliques de la Clinique Médicale B des Hôpitaux Universitaires de Strasbourg, 1, Place de l Hopital, 67091 Strasbourg, France
    Ann Endocrinol (Paris) 64:376-82. 2003
    ..PROSPECTS AND PROJECTS: Validate the concept of NDB12 and the usefulness of oral cobalamin therapy, establish the relevance of the new clinical manifestations...
  60. ncbi request reprint [A diagnosis not as mechanical as it seems to be...]
    C Coca
    Service de Medecine Interne, diabète et maladies métaboliques, clinique médicale B, Hopitaux Universitaires de Strasbourg, 1, Place de l Hopital, 67091 Strasbourg Cedex, France
    Rev Med Interne 25:S239-41. 2004
  61. doi request reprint [Thoracic impairment from familial Mediterranean fever: review of the literature and a case study]
    G Wirtz
    Service de Pneumologie, CHU de Strasbourg, 1, Place de l Hopital, 67000, Strasbourg, France
    Rev Pneumol Clin 65:313-7. 2009
    ..The authors also discuss the association of mesothelioma and FMF. Colchicine is successfully used in the treatment of FMF...
  62. ncbi request reprint [Hypersensitivity syndrome : a rare but severe adverse effect of antithyroid drugs]
    S Vinzio
    Service de Medecine interne et nutrition, Hopital de Hautepierre, 67098 Strasbourg Cedex, France
    Ann Endocrinol (Paris) 61:151-3. 2000
    ..Pathogenesis of the hypersensitivity syndrome is discussed. Antithyroid drugs are rarely involved in the syndrome but cases with vasculitis have been described. In our patient, the role of excessive dose is possible...
  63. ncbi request reprint [Development and long-term prognosis of unexplained persistent inflammatory biologic syndromes]
    A E Perrin
    Service de Medecine interne et nutrition, Hopital de Hautepierre, Avenue Moliere, 67098 Strasbourg, France
    Rev Med Interne 23:683-9. 2002
    ..The aim of this study is to describe the long-term follow-up and the prognosis of a group of patients hospitalised for an inflammatory syndrome and discharged without causal diagnosis...
  64. doi request reprint [Idiosyncratic drug-induced thrombocytopenia]
    K Serraj
    Service de Medecine Interne, diabète et maladies métaboliques, clinique médicale B, Hopitaux Universitaires de Strasbourg, 1, porte de l Hôpital, BP 426, Strasbourg Cedex, France
    Rev Med Interne 30:866-71. 2009
    ..The treatment is based on the discontinuation of the incriminated drug and on supportive measures that depend on the severity of the clinical features...
  65. doi request reprint Multiorgan failure caused by intravascular lymphoma: a highly rare and malignant hemopathy mimicking multisystemic disease
    T Weitten
    Department of Intensive Care, Hospital of Mulhouse, France
    South Med J 101:952-4. 2008
    ..Despite the heterogeneous presentation of this lymphoma, some clinical and biological investigations should prevail clinicians to do tissue biopsy which is required to make the diagnosis...
  66. ncbi request reprint [Low vitamin B12 levels in elderly patients cured within one week by oral cobalamin therapy]
    G Kaltenbach
    Centre de Gerontologie, Hôpital de la Robertsau, Strasbourg
    Presse Med 34:358-62. 2005
    ..The aim of this study was to determine the initial dose of oral cyanocobalamin that would correct the B12 vitamin deficiency within one week...
  67. ncbi request reprint Idiopathic thrombocytopenic purpura: a retrospective analysis in 139 patients of the influence of age on the response to corticosteroids, splenectomy and danazol
    Emmanuel Andres
    Department of Internal Medicine, Hopitaux Universitaires de Strasbourg, Strasbourg, France
    Drugs Aging 20:841-6. 2003
    ..To review the influence of age on the response of patients with idiopathic thrombocytopenic purpura (ITP) to corticosteroids, splenectomy and danazol...
  68. ncbi request reprint Glibenclamide-induced acute haemolytic anaemia revealing a G6PD-deficiency
    Stephane Vinzio
    Service de Médecine Interne et de Nutrition, Hopital de Hautepierre, 67098 Strasbourg Cedex, France
    Diabetes Res Clin Pract 64:181-3. 2004
    ..We reviewed the literature and discuss the relationship between glibenclamide and haemolytic crisis and between G6PD-deficiency and diabetes...
  69. ncbi request reprint [Early response to oral cobalamin therapy in older patients with vitamin B12 deficiency]
    Georges Kaltenbach
    Centre de Gerontologie, Hôpital de la Robertsau Hôpitaux Universitaires, 83, rue Himmerich, 67000 Strasbourg
    Ann Med Interne (Paris) 154:91-5. 2003
    ..The aim of this study was to determine whether oral cobalamin treatment may be an effective therapy for treating older patients with cobalamin deficiency related to nutritional deficiency and food-cobalamin malabsorption...
  70. ncbi request reprint [Isolated neurologic disorders disclosing Biermer's disease in young subjects]
    E Andres
    Service de Medecine Interne, Hopitaux Universitaires de Strasbourg, Hopital de Hautepierre, Avenue Moliere, 67098 Strasbourg, France
    Rev Med Interne 22:389-93. 2001
    ..In young subjects, the discovery of a cobalamine deficiency (Biermer's disease) at the time of neuropsychiatric disorders even of isolated MRI anomalies is a rare event (less than 0.01%)...
  71. ncbi request reprint [Pancytopenia related to low-dose methotrexate: study of five cases and review of the literature]
    K Serraj
    Service de Medecine Interne, diabète et maladies métaboliques, clinique médicale B du CHU de Strasbourg, 1, Place de l Hopital, 67091 Strasbourg Cedex, France
    Rev Med Interne 28:584-8. 2007
    ..The aim of this study is to report personal experience of pancytopenia related to low-dose methotrexate and to review the literature...
  72. doi request reprint [Food-cobalamin syndrome]
    Khalid Serraj
    Service de Medecine Interne, diabète et maladies métaboliques, clinique médicale B, Hopitaux Universitaires de Strasbourg, F 67091 Strasbourg, France
    Presse Med 38:55-62. 2009
    ..Studies are in the way to better characterize the food-cobalamin malabsorption in a clinical practice perspective and to validate the usefulness of oral cobalamin therapy...
  73. doi request reprint The spectrum of Evans syndrome in adults: new insight into the disease based on the analysis of 68 cases
    Marc Michel
    Department of Internal Medicine, Henri Mondor Hospital, Assistance Publique Hopitaux de Paris, Paris XII University, Creteil, France
    Blood 114:3167-72. 2009
    ..In conclusion, ES is a potentially life-threatening condition that may be associated with other underlying autoimmune or lymphoproliferative disorders...
  74. ncbi request reprint Treatment of 21 cases of invasive mucormycosis with amphotericin B colloidal dispersion
    R Herbrecht
    Département d Onco Hématologie, Hopital de Hautepierre, Strasbourg, France
    Eur J Clin Microbiol Infect Dis 20:460-6. 2001
    ..No renal or hepatic toxicity was observed. These results compare favourably with the results of standard treatment and suggest that ABCD combined with surgery may be a useful therapy in patients with mucormycosis...
  75. doi request reprint [Cytomegalovirus infection in an immunocompetent patient complicated with pulmonary embolism and mimicking giant cell arteritis associated with polymyalgia rheumatica]
    G Wirtz
    Service de Medicine Interne, diabète et maladies métaboliques, clinique médicale B, Hopitaux Universitaires de Strasbourg, 1, Place de l Hopital, 67091 Strasbourg Cedex, France
    Med Mal Infect 38:287-9, 248. 2008
    ..We review and discuss the venous prothrombic properties of CMV in immunocompetent patients...
  76. ncbi request reprint Prognostic factors of hematological recovery in life-threatening nonchemotherapy drug-induced agranulocytosis. A study of 91 patients from a single center
    Frederic Maloisel
    Department of Hematology Oncology, Hopitaux Universitaires de Strasbourg, France
    Presse Med 33:1164-8. 2004
    ..We studied clinical factors that may influence the duration of hematological recovery to reach neutrophil counts and thus, indirectly, the prognosis in patients with life-threatening drug-induced agranulocytosis (DIA)...
  77. ncbi request reprint Danazol therapy in patients with chronic idiopathic thrombocytopenic purpura: long-term results
    Frederic Maloisel
    Departments of Hematology and Oncology, Strasbourg, France
    Am J Med 116:590-4. 2004
    ..We studied whether danazol, an attenuated androgen, is useful in this setting...
  78. ncbi request reprint [Recurrent facial palsy, primary Gougerot-Sjögren's syndrome and vitamin B12 deficiency]
    Emmanuel Rousso
    Service de Medecine Interne, diabète et maladies métaboliques de la clinique médicale B, Hopitaux Universitaires de Strasbourg
    Presse Med 34:107-8. 2005
    ..Involvement of the V, III and VII nerves has been reported, the most characteristic being nerve V, notably its lower branch. Rare, well documented, cases of facial palsy have also been described...
  79. doi request reprint Idiopathic thrombocytopenic purpura in elderly patients: a study of 47 cases from a single reference center
    Samira Daou
    Department of Internal Medicine, Hopitaux Universitaires de Strasbourg, Strasbourg, France
    Eur J Intern Med 19:447-51. 2008
    ..Idiopathic thrombocytopenic purpura (ITP) is often diagnosed in the elderly, but no specific guidelines exist for such patients. We describe our experience with ITP management in elderly patients and analyze the therapeutic response...
  80. doi request reprint [Idiosyncratic drug-induced agranulocytosis]
    Laure Federici
    Service de Medecine Interne, Hopital Pasteur, F 68000 Colmar, France
    Presse Med 37:1327-33. 2008
    ..Improvement in the management of infectious complications and the use of hematopoietic growth factors in severe cases helps explain that mortality rate has fallen to less than 5%...
  81. doi request reprint A French national research project to the creation of an auscultation's school: the ASAP project
    Emmanuel Andres
    Department of Internal Medicine, clinique médicale B, CHRU Strasbourg, Strasbourg, France
    Eur J Intern Med 20:323-7. 2009
    ..This auscultation's school will be destined to the initial and continuous formation of the medical attendants...
  82. ncbi request reprint [Chronic fever revealing an urachal cyst]
    Thierry Weitten
    Service de Medecine Interne, diabète et maladies métaboliques, clinique médicale B, Hopital de Hautepierre, Strasbourg
    Ann Med Interne (Paris) 154:541-3. 2003
    ..This later may also be asymptomatic or lead to local inflammation or inflammatory pseudo-tumor. We report an original observation of chronic fever revealing an urachal cyst in a 21-Year-old male...