Mounira Amor-Gueret

Summary

Country: France

Publications

  1. ncbi Bloom syndrome, genomic instability and cancer: the SOS-like hypothesis
    Mounira Amor-Gueret
    UMR 2027 CNRS, Institut Curie, Group Instabilité Génétique et Cancérogenèse, Batiment 110, Centre Universitaire, 91405 Orsay Cedex, France
    Cancer Lett 236:1-12. 2006
  2. pmc Bloom's syndrome and PICH helicases cooperate with topoisomerase IIα in centromere disjunction before anaphase
    Sébastien Rouzeau
    Institut Curie, Centre de Recherche, Centre Universitaire, Bat, Orsay, France
    PLoS ONE 7:e33905. 2012
  3. doi Pyrimidine pool imbalance induced by BLM helicase deficiency contributes to genetic instability in Bloom syndrome
    Pauline Chabosseau
    Institut Curie, Centre de Recherche, Orsay, France
    Nat Commun 2:368. 2011
  4. doi The Bloom syndrome protein limits the lethality associated with RAD51 deficiency
    Kenza Lahkim Bennani-Belhaj
    Institut Curie, Centre de Recherche, Centre Universitaire, Orsay, France
    Mol Cancer Res 8:385-94. 2010
  5. ncbi The Bloom syndrome helicase is a substrate of the mitotic Cdc2 kinase
    Emilie Bayart
    CNRS, UMR 2027, Institut Curie, Section de Recherche, Centre Universitaire, Orsay, France
    Cell Cycle 5:1681-6. 2006
  6. pmc Structural and functional analyses of disease-causing missense mutations in Bloom syndrome protein
    Rong Bing Guo
    CNRS, UMR 2027, Institut Curie Section de Recherche, Centre Universitaire, Batiment 110, F 91405 Orsay, France
    Nucleic Acids Res 35:6297-310. 2007
  7. ncbi DNA damage: RNA-binding proteins protect from near and far
    Martin Dutertre
    Institut Curie, Centre de Recherche, Orsay, France CNRS UMR3348, Genotoxic Stress and Cancer, Centre Universitaire, Orsay, France
    Trends Biochem Sci 39:141-9. 2014
  8. doi Three new BLM gene mutations associated with Bloom syndrome
    Mounira Amor-Gueret
    Institut Curie, Centre de Recherche, Orsay, France
    Genet Test 12:257-61. 2008

Collaborators

Detail Information

Publications8

  1. ncbi Bloom syndrome, genomic instability and cancer: the SOS-like hypothesis
    Mounira Amor-Gueret
    UMR 2027 CNRS, Institut Curie, Group Instabilité Génétique et Cancérogenèse, Batiment 110, Centre Universitaire, 91405 Orsay Cedex, France
    Cancer Lett 236:1-12. 2006
    ..This mechanism may be dependent on the RAD51 gene family, and involved in carcinogenesis in the general population...
  2. pmc Bloom's syndrome and PICH helicases cooperate with topoisomerase IIα in centromere disjunction before anaphase
    Sébastien Rouzeau
    Institut Curie, Centre de Recherche, Centre Universitaire, Bat, Orsay, France
    PLoS ONE 7:e33905. 2012
    ....
  3. doi Pyrimidine pool imbalance induced by BLM helicase deficiency contributes to genetic instability in Bloom syndrome
    Pauline Chabosseau
    Institut Curie, Centre de Recherche, Orsay, France
    Nat Commun 2:368. 2011
    ..Nucleotide pool disequilibrium could be a general phenomenon in a large spectrum of precancerous and cancer cells...
  4. doi The Bloom syndrome protein limits the lethality associated with RAD51 deficiency
    Kenza Lahkim Bennani-Belhaj
    Institut Curie, Centre de Recherche, Centre Universitaire, Orsay, France
    Mol Cancer Res 8:385-94. 2010
    ..These findings provide insight into the molecular basis of some cancers possibly associated with variants of the RAD51 gene family...
  5. ncbi The Bloom syndrome helicase is a substrate of the mitotic Cdc2 kinase
    Emilie Bayart
    CNRS, UMR 2027, Institut Curie, Section de Recherche, Centre Universitaire, Orsay, France
    Cell Cycle 5:1681-6. 2006
    ..Our results identify BLM helicase as a new substrate for cdc2, which may have potential physiological implications for the role of BLM in mitosis...
  6. pmc Structural and functional analyses of disease-causing missense mutations in Bloom syndrome protein
    Rong Bing Guo
    CNRS, UMR 2027, Institut Curie Section de Recherche, Centre Universitaire, Batiment 110, F 91405 Orsay, France
    Nucleic Acids Res 35:6297-310. 2007
    ..Our findings will help to explain the mechanism underlying BLM catalysis and interpreting new BLM causing mutations identified in the future...
  7. ncbi DNA damage: RNA-binding proteins protect from near and far
    Martin Dutertre
    Institut Curie, Centre de Recherche, Orsay, France CNRS UMR3348, Genotoxic Stress and Cancer, Centre Universitaire, Orsay, France
    Trends Biochem Sci 39:141-9. 2014
    ..Finally, because DNA damage modifies RBP localization and binding to different RNA/DNA molecules, we propose that upon DNA damage, RBPs coordinately regulate various aspects of both RNA and DNA metabolism. ..
  8. doi Three new BLM gene mutations associated with Bloom syndrome
    Mounira Amor-Gueret
    Institut Curie, Centre de Recherche, Orsay, France
    Genet Test 12:257-61. 2008
    ..All these mutations introduce a stop codon, and may therefore be considered to have deleterious biological effect. This approach should make it possible to identify new mutations and to correlate them with clinical information...