P Amarenco

Summary

Country: France

Publications

  1. ncbi request reprint Stroke prevention, blood cholesterol and statins
    Pierre Amarenco
    Department of Neurology and Stroke Centre, Bichat University Hospital and Medical School, Denis Diderot University Paris VII, 46 rue Henri Huchard, 75018 Paris, France
    Acta Neurol Taiwan 14:96-112. 2005
  2. ncbi request reprint Hypercholesterolemia, lipid-lowering agents, and the risk for brain infarction
    P Amarenco
    Department of Neurology Bichat Hospital, Rene Descartes University and Stroke Unit, Paris, France
    Neurology 57:S35-44. 2001
  3. ncbi request reprint Statins for stroke prevention: disappointment and hope
    Pierre Amarenco
    Department of Neurology and Stroke Center, Bichat University Hospital and Medical School, Denis Diderot University Paris VII, 46 rue Henri Huchard, 75018 Paris, France
    Circulation 109:III44-9. 2004
  4. ncbi request reprint Should the MATCH results be extrapolated to all stroke patients and affect ongoing trials evaluating clopidogrel plus aspirin?
    Pierre Amarenco
    Department of Neurology and Stroke Centre, Bichat Hospital and Medical School, 46 rue Henri Huchard, Paris, France 75018
    Stroke 35:2606-8. 2004
  5. ncbi request reprint Statins in stroke prevention and carotid atherosclerosis: systematic review and up-to-date meta-analysis
    Pierre Amarenco
    Department of Neurology and Stroke Centre, Bichat University Hospital and Medical School, Denis Diderot University Paris VII, 46 rue Henri Huchard, 75018 Paris, France
    Stroke 35:2902-9. 2004
  6. ncbi request reprint Effects of intense low-density lipoprotein cholesterol reduction in patients with stroke or transient ischemic attack: the Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL) trial
    Pierre Amarenco
    Department of Neurology and Stroke Centre, Bichat University Hospital, Denis Diderot University and Medical School, 46, rue Henri Huchard, 75018, Paris, France
    Stroke 38:3198-204. 2007
  7. ncbi request reprint Effect of statins in stroke prevention
    Pierre Amarenco
    Department of Neurology and Stroke Centre, Bichat University Hospital, Denis Diderot University and Medical School, Paris, France
    Curr Opin Lipidol 16:614-8. 2005
  8. ncbi request reprint Statins and stroke prevention
    Pierre Amarenco
    Department of Neurology and Stroke Center, Bichat Claude Bernard University Hospital and Medical School, Denis Diderot University Paris VII, Paris, France
    Cerebrovasc Dis 17:81-8. 2004
  9. doi request reprint Rationale and design of a randomized, double-blind, parallel-group study of terutroban 30 mg/day versus aspirin 100 mg/day in stroke patients: the prevention of cerebrovascular and cardiovascular events of ischemic origin with terutroban in patients with
    M G Bousser
    Hôpital Lariboisière AP HP, INSERM U 740, Paris, France
    Cerebrovasc Dis 27:509-18. 2009
  10. ncbi request reprint Mitral valve strands and the risk of ischemic stroke in elderly patients. The French Study of Aortic Plaques in Stroke (FAPS) Investigators
    A Cohen
    Service de cardiologie, Hopital Saint Antoine, Universite Pierre et Marie Curie, Paris, France
    Stroke 28:1574-8. 1997

Detail Information

Publications87

  1. ncbi request reprint Stroke prevention, blood cholesterol and statins
    Pierre Amarenco
    Department of Neurology and Stroke Centre, Bichat University Hospital and Medical School, Denis Diderot University Paris VII, 46 rue Henri Huchard, 75018 Paris, France
    Acta Neurol Taiwan 14:96-112. 2005
    ....
  2. ncbi request reprint Hypercholesterolemia, lipid-lowering agents, and the risk for brain infarction
    P Amarenco
    Department of Neurology Bichat Hospital, Rene Descartes University and Stroke Unit, Paris, France
    Neurology 57:S35-44. 2001
    ..However, for the remaining patients with ischemic stroke, there is no proven therapeutic approach, and several large randomized, placebo-controlled trials are under way or planned for this indication...
  3. ncbi request reprint Statins for stroke prevention: disappointment and hope
    Pierre Amarenco
    Department of Neurology and Stroke Center, Bichat University Hospital and Medical School, Denis Diderot University Paris VII, 46 rue Henri Huchard, 75018 Paris, France
    Circulation 109:III44-9. 2004
    ..Treatment strategies based on global cardiovascular risk may be most effective. Additional studies in patients representative of the typical stroke population are needed...
  4. ncbi request reprint Should the MATCH results be extrapolated to all stroke patients and affect ongoing trials evaluating clopidogrel plus aspirin?
    Pierre Amarenco
    Department of Neurology and Stroke Centre, Bichat Hospital and Medical School, 46 rue Henri Huchard, Paris, France 75018
    Stroke 35:2606-8. 2004
  5. ncbi request reprint Statins in stroke prevention and carotid atherosclerosis: systematic review and up-to-date meta-analysis
    Pierre Amarenco
    Department of Neurology and Stroke Centre, Bichat University Hospital and Medical School, Denis Diderot University Paris VII, 46 rue Henri Huchard, 75018 Paris, France
    Stroke 35:2902-9. 2004
    ..Statin trials have now included >90,000 patients. We have determined the effect of statins and LDL-C reduction on stroke prevention...
  6. ncbi request reprint Effects of intense low-density lipoprotein cholesterol reduction in patients with stroke or transient ischemic attack: the Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL) trial
    Pierre Amarenco
    Department of Neurology and Stroke Centre, Bichat University Hospital, Denis Diderot University and Medical School, 46, rue Henri Huchard, 75018, Paris, France
    Stroke 38:3198-204. 2007
    ..In this exploratory analysis, our aim was to evaluate the benefit and risks associated with achieving a >or=50% low-density lipoprotein cholesterol (LDL-C) reduction from baseline...
  7. ncbi request reprint Effect of statins in stroke prevention
    Pierre Amarenco
    Department of Neurology and Stroke Centre, Bichat University Hospital, Denis Diderot University and Medical School, Paris, France
    Curr Opin Lipidol 16:614-8. 2005
    ..This paper reviews recent studies into the outcomes of clinical trials in which statin therapy has been used in the prevention and treatment of strokes...
  8. ncbi request reprint Statins and stroke prevention
    Pierre Amarenco
    Department of Neurology and Stroke Center, Bichat Claude Bernard University Hospital and Medical School, Denis Diderot University Paris VII, Paris, France
    Cerebrovasc Dis 17:81-8. 2004
    ..This would be one of the most significant advances in stroke and vascular dementia prevention since the era of aspirin therapy...
  9. doi request reprint Rationale and design of a randomized, double-blind, parallel-group study of terutroban 30 mg/day versus aspirin 100 mg/day in stroke patients: the prevention of cerebrovascular and cardiovascular events of ischemic origin with terutroban in patients with
    M G Bousser
    Hôpital Lariboisière AP HP, INSERM U 740, Paris, France
    Cerebrovasc Dis 27:509-18. 2009
    ....
  10. ncbi request reprint Mitral valve strands and the risk of ischemic stroke in elderly patients. The French Study of Aortic Plaques in Stroke (FAPS) Investigators
    A Cohen
    Service de cardiologie, Hopital Saint Antoine, Universite Pierre et Marie Curie, Paris, France
    Stroke 28:1574-8. 1997
    ..Their nature and their potential for embolization are largely unknown. The objective was to estimate the risk of brain infarction in patients with mitral valve strands...
  11. ncbi request reprint Aortic plaque morphology and vascular events: a follow-up study in patients with ischemic stroke. FAPS Investigators. French Study of Aortic Plaques in Stroke
    A Cohen
    Service de cardiologie, Saint Antoine University and Medical School, Paris, France
    Circulation 96:3838-41. 1997
    ..The purpose of this study was to evaluate the impact, if any, of plaque morphology (ulceration, hypoechoic plaques or calcification) on the risk of subsequent vascular events...
  12. ncbi request reprint Genetic susceptibility and ischaemic stroke
    A Elbaz
    INSERM Unité 360, Hopital de la Salpetriere, Paris, France
    Curr Opin Neurol 12:47-55. 1999
    ..This may have therapeutic and preventive implications...
  13. doi request reprint Prevalence of subdiaphragmatic visceral infarction in cardioembolic stroke
    T Slaoui
    Department of Neurology and Stroke Center, Bichat University Hospital, Paris, France
    Neurology 74:1030-2. 2010
    ..Coexistence of subdiaphragmatic visceral infarction (SDVI; e.g., renal, splenic, hepatic, bowel infarction) may be a suggestion of a common source of embolism. One large autopsy study found SDVI in 21.5% of patients with fatal stroke...
  14. doi request reprint Relative and cumulative effects of lipid and blood pressure control in the Stroke Prevention by Aggressive Reduction in Cholesterol Levels trial
    Pierre Amarenco
    INSERM U 698, Denis Diderot University Paris VII, Department of Neurology, Bichat University Hospital, Paris, France
    Stroke 40:2486-92. 2009
    ....
  15. ncbi request reprint Common carotid artery intima-media thickness and brain infarction : the Etude du Profil Génétique de l'Infarctus Cérébral (GENIC) case-control study. The GENIC Investigators
    P J Touboul
    Department of Neurology, Lariboisiere Hospital, Paris, France
    Circulation 102:313-8. 2000
    ..73; 95% confidence interval, 1.45 to 2.07). CONCLUSIONS-An increased CCA-IMT was associated with BI, both overall and in the main subtypes. An increased IMT may help select patients at high risk for BI...
  16. doi request reprint The Prevention of cerebrovascular and cardiovascular Events of ischemic origin with teRutroban in patients with a history oF ischemic strOke or tRansient ischeMic attack (PERFORM) study: baseline characteristics of the population
    M G Bousser
    Department of Neurology, Hôpital Lariboisière AP HP, INSERM U 740, Paris, France
    Cerebrovasc Dis 27:608-13. 2009
    ..Here we describe the baseline characteristics of the population...
  17. doi request reprint Baseline blood pressure, low- and high-density lipoproteins, and triglycerides and the risk of vascular events in the Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL) trial
    Pierre Amarenco
    INSERM U 698 and Denis Diderot University, Paris, France
    Atherosclerosis 204:515-20. 2009
    ....
  18. pmc Mannheim carotid intima-media thickness and plaque consensus (2004-2006-2011). An update on behalf of the advisory board of the 3rd, 4th and 5th watching the risk symposia, at the 13th, 15th and 20th European Stroke Conferences, Mannheim, Germany, 2004, B
    P J Touboul
    Stroke Center Bichat Hospital 46, rue Henri Huchard, FR 75018 Paris, France
    Cerebrovasc Dis 34:290-6. 2012
    ..IMT results are applied to individual patients as an integrated assessment of cardiovascular risk factors. However, this document recommends against serial monitoring in individual patients...
  19. doi request reprint Endarterectomy Versus Angioplasty in Patients with Symptomatic Severe Carotid Stenosis (EVA-3S) trial: results up to 4 years from a randomised, multicentre trial
    Jean Louis Mas
    Hôpitaux Sainte Anne, Universite Paris Descartes, Paris, France
    Lancet Neurol 7:885-92. 2008
    ..We now report the results up to 4 years...
  20. doi request reprint Prevalence of nephroangiosclerosis in patients with fatal stroke
    H Abboud
    Assistance Publique Hopitaux de Paris, Department of Neurology and Stroke Centre, Bichat University Hospital, Paris, France
    Neurology 72:899-904. 2009
    ..Glomerular filtration rate and decline in renal function can be improved by global cardiovascular prevention. However, the prevalence of nephroangiosclerosis in patients with stroke is unknown...
  21. ncbi request reprint Stroke prevention, blood cholesterol, and statins
    Pierre Amarenco
    Department of Neurology and Stroke Centre, Bichat Claude Bernard University Hospital and Medical School, Denis Diderot University Paris VII, France
    Lancet Neurol 3:271-8. 2004
    ..Treatment strategies on the basis of global cardiovascular risk may be most effective. Additional studies in patients representative of the typical stroke population are needed...
  22. doi request reprint Coronary heart disease risk in patients with stroke or transient ischemic attack and no known coronary heart disease: findings from the Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL) trial
    Pierre Amarenco
    Department of Neurology and Stroke Centre, INSERM U 698 and Denis Diderot University Paris VII, Bichat Claude Bernard University Hospital, 46 rue Henri Huchard, 75018 Paris, France
    Stroke 41:426-30. 2010
    ..We evaluated the risk of developing clinically recognized CHD in SPARCL patients...
  23. doi request reprint Results of the Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL) trial by stroke subtypes
    Pierre Amarenco
    INSERM U 698 and Denis Diderot University, Paris, France
    Stroke 40:1405-9. 2009
    ..We tested the hypothesis that the benefit of treatment varies according to index event stroke subtype...
  24. ncbi request reprint Recurrent stroke and vascular events in elderly patients with anticardiolipin antibodies: a prospective study
    O Heinzlef
    Department of Neurology, Vasculaire Saint Antoine Hospital, Paris, France
    J Neurol 248:373-9. 2001
    ..In contrast to young patients, elderly patients with 10 or more GPL units aCL and negative for anti-beta2 glycoprotein I do not seem to have a higher risk of vascular events...
  25. doi request reprint Cerebral microbleeds are frequent in infective endocarditis: a case-control study
    Isabelle Klein
    Department of Radiology, Bichat University Hospital, 75018 Paris, France
    Stroke 40:3461-5. 2009
    ..CMBs have been reported in isolated cases of infective endocarditis (IE), but their frequency and the association of CMBs with IE have not yet been studied...
  26. ncbi request reprint Chlamydia pneumoniae seropositivity in aetiological subtypes of brain infarction and carotid atherosclerosis: a case control study
    S Alamowitch
    Stroke Unit, Department of Neurology, Tenon University Hospital, AP HP, 4 rue de la Chine, Paris, France
    J Neurol Neurosurg Psychiatry 79:147-51. 2008
    ..We investigated Chlamydia pneumoniae infection in a large cohort of patients with BI according to aetiological subtypes and carotid atherosclerosis...
  27. ncbi request reprint Atorvastatin in prevention of stroke and transient ischaemic attack
    Pierre Amarenco
    Bichat University Hospital, Department of Neurology and Stroke Centre, 46 rue Henri Huchard, 75018 Paris, France
    Expert Opin Pharmacother 8:2789-97. 2007
    ..Statins are effective in reducing both first-ever and recurrent stroke, and this effect seems driven by the extent of LDL-C lowering...
  28. doi request reprint Placebo-controlled trial of high-dose atorvastatin in patients with severe cerebral small vessel disease
    Philippa C Lavallee
    Department of Neurology, Stroke Centre, Bichat University Hospital, Denis Diderot University and Medical School, Paris, France
    Stroke 40:1721-8. 2009
    ..We sought to determine whether high-dose atorvastatin increases CVR compared with placebo in patients with severe small vessel disease...
  29. ncbi request reprint Polypill strategy vs. prevention clinics for stroke prevention
    Pierre Amarenco
    Department of Neurology and Stroke Center, Bichat Hospital, Denis Diderot University and Medical School, Paris, France
    Cerebrovasc Dis 21:35-40. 2006
    ....
  30. doi request reprint Yield of systematic transcranial Doppler in patients with transient ischemic attack
    Elena Meseguer
    INSERM U698 and Denis Diderot University and Medical School, Paris, France
    Ann Neurol 68:9-17. 2010
    ..Our aim was to determine whether the use of transcranial Doppler (TCD) examination on arrival at the TIA clinic yields additional information that facilitates the identification of patients at high risk of stroke recurrence...
  31. ncbi request reprint Statin therapy and stroke prevention: what was known, what is new and what is next?
    Mikael Mazighi
    Department of Neurology and Stroke Centre, Bichat Hospital, Denis Diderot University and Medical School, Paris, France
    Curr Opin Lipidol 18:622-5. 2007
    ..Randomized trials have shown that statins may reduce the risk of primary stroke. There is no evidence however that statins can reduce recurrent stroke incidence...
  32. ncbi request reprint Cost of a recurrent vs. cost of first-ever stroke over an 18-month period
    J F Spieler
    Centre of Health Economic and Administration Research CHEAR, Institut National de la Santé et de la Recherche Médicale INSERM U 537, Paris, France
    Eur J Neurol 10:621-4. 2003
    ..This study suggests that the costs of recurrent BI are roughly similar to the costs of first-ever BI, which may be helpful when studying the cost-effectiveness of secondary stroke prevention trials...
  33. ncbi request reprint Lipid lowering and recurrent stroke: a definitive answer?
    Pierre Amarenco
    Department of Neurology and Stroke Centre, Bichat University Hospital, Denis Diderot University and Medical School, Paris, France
    Int J Stroke 2:111-3. 2007
  34. ncbi request reprint Aortic arch atheroma and the risk of stroke
    Pierre Amarenco
    Department of Neurology and Stroke Centre, Bichat Hospital, 46 rue Henri Huchard, 75018 Paris, France
    Curr Atheroscler Rep 8:343-6. 2006
    ..In this category of patients new potential causes, such as aortic arch atheroma in the elderly, have been investigated in the past two decades...
  35. ncbi request reprint The paradox of cholesterol and stroke
    Pierre Amarenco
    INSERM U 698, and Université Paris 7 Denis Diderot, Paris, France
    Lancet 370:1803-4. 2007
  36. ncbi request reprint Carotid intima-media thickness, plaques, and Framingham risk score as independent determinants of stroke risk
    Pierre Jean Touboul
    Department of Neurology and Stroke Center, Bichat University Hospital and Medical School, Paris, France
    Stroke 36:1741-5. 2005
    ..The purpose of this study was to correlate Framingham risk score (FRS) with CCA-IMT and CPs and evaluate their respective contribution to stroke risk...
  37. ncbi request reprint A transient ischaemic attack clinic with round-the-clock access (SOS-TIA): feasibility and effects
    Philippa C Lavallee
    Department of Neurology and Stroke Centre, Bichat Claude Bernard University Hospital, Denis Diderot University and Medical School Paris VII, Assistance Publique Hopitaux de Paris, Paris, France
    Lancet Neurol 6:953-60. 2007
    ..We evaluated the effects of rapid assessment of patients with TIA on clinical decision making, length of hospital stay, and subsequent stroke rates...
  38. ncbi request reprint Cryptogenic stroke, aortic arch atheroma, patent foramen ovale, and the risk of stroke
    Pierre Amarenco
    Department of Neurology and Stroke Centre, Bichat University Hospital and Medical School, Paris, France
    Cerebrovasc Dis 20:68-74. 2005
  39. pmc Multiple microembolic borderzone brain infarctions and endomyocardial fibrosis in idiopathic hypereosinophilic syndrome and in Schistosoma mansoni infestation
    M Sarazin
    Department of Psychogeriatrics, Bretonneau Hospital, Paris, France
    J Neurol Neurosurg Psychiatry 75:305-7. 2004
    ....
  40. ncbi request reprint Frequency of migraine attacks following stroke starts to decrease before PFO closure
    B Lapergue
    Department of Neurology and Stroke Center, Bichat University Hospital, Denis Diderot University and Medical School, 46 rue Henri Huchard, 75018 Paris, France
    Neurology 67:1099-100. 2006
  41. pmc Patent foramen ovale and the risk of stroke: smoking gun guilty by association?
    P Amarenco
    Department of Neurology and Stroke Centre, Bichat University Hospital and Medical School, Bichat Hospital, 46 rue Henri Huchard, 75018, Paris, France
    Heart 91:441-3. 2005
  42. doi request reprint New approach to stroke subtyping: the A-S-C-O (phenotypic) classification of stroke
    P Amarenco
    Department of Neurology and Stroke Center, INSERM U 698 and Paris Diderot University, Bichat University Hospital, Paris, France
    Cerebrovasc Dis 27:502-8. 2009
    ..g. for genetic analysis purpose), while clinical trials can focus on 1 or several of these 4 phenotypes (e.g. focus on patients A1-A2-A3)...
  43. doi request reprint Implications of the ACCORD lipid study: perspective from the Residual Risk Reduction Initiative (R(3)i)
    J C Fruchart
    R3i Foundation, Paris, France
    Curr Med Res Opin 26:1793-7. 2010
    ..This commentary from the Residual Risk Reduction Initiative (R(3)i), discusses the ACCORD Lipid study results and the next steps to establish the clinical relevance of these findings...
  44. doi request reprint Atherothrombosis and the role of antiplatelet therapy
    Ph G Steg
    INSERM U 698, Universite Paris Diderot, Assistance Publique Hopitaux de Paris, Paris, France
    J Thromb Haemost 9:325-32. 2011
    ....
  45. ncbi request reprint Association studies between haemochromatosis gene mutations and the risk of cardiovascular diseases
    G Hetet
    INSERM U409 and Association Claude Bernard, Paris, France, Salpetriere Hospital, Paris, France
    Eur J Clin Invest 31:382-8. 2001
    ..Positive association studies have been recently published between cardiovascular diseases and heterozygosity for the major mutation C282Y in the haemochromatosis gene HFE...
  46. ncbi request reprint Determinants of outcome and safety of intravenous rt-PA therapy in the very old: a clinical registry study and systematic review
    Elena Meseguer
    Department of Neurology and Stroke Centre, Bichat University Hospital, 46, rue Henri Huchard, 75018 Paris, France
    Age Ageing 37:107-11. 2008
  47. ncbi request reprint [Thrombolysis and acute cerebral infarction]
    Halim Abboud
    Service de Neurologie et Centre d Accueil et de Traitement de l Attaque Cérébrale, Groupe Hospitalier Bichat Claude Bernard, 46, rue Henri Huchard 75877 Paris Cedex 18, France
    Med Sci (Paris) 20:1104-8. 2004
    ..Increasing stroke awareness in the community, creating stroke unit and physicians education are necessary to extend the effective use of acute treatment in cerebral infarct to a larger group of patients...
  48. ncbi request reprint The dynamics of statins: from event prevention to neuroprotection
    Pierre Amarenco
    Department of Neurology, Stroke Centre, Denis Diderot University and Medical School, Bichat Hospital, Paris, France
    Stroke 37:294-6. 2006
  49. doi request reprint Meta-analysis of the effect of nicotinic acid alone or in combination on cardiovascular events and atherosclerosis
    Eric Bruckert
    Department of Endocrinology, Pitie Salpetriere University Hospital, Pierre and Marie Curie University, 83 bd de l hopital, 75651, Paris, France
    Atherosclerosis 210:353-61. 2010
    ....
  50. ncbi request reprint Blood lipids in brain infarction subtypes
    Pierre Amarenco
    Department of Neurology and Stroke Centre, Bichat Hospital, Denis Diderot University, INSERM U 360, Paris, France
    Cerebrovasc Dis 22:101-8. 2006
    ..Little is known about the relationship between hypercholesterolaemia and specific aetiological subtypes of brain infarction (BI)...
  51. doi request reprint Lipid management in the prevention of stroke: review and updated meta-analysis of statins for stroke prevention
    Pierre Amarenco
    INSERM U 698 clinical research in atherothrombosis and Paris Diderot University, Paris, France
    Lancet Neurol 8:453-63. 2009
    ..8 mmol/L (70 mg/dL), the effects of triglyceride-lowering therapy alone or in combination with statins, and the effects of treatments to raise HDL cholesterol concentrations...
  52. ncbi request reprint High-density lipoprotein-cholesterol and risk of stroke and carotid atherosclerosis: a systematic review
    Pierre Amarenco
    Department of Neurology and Stroke Centre, Denis Diderot University and Medical School, Bichat University Hospital, 46 rue Henri Huchard, 75018 Paris, France
    Atherosclerosis 196:489-96. 2008
    ..Epidemiological studies have found no relationship between total cholesterol and stroke risk, but little attention has been paid to high-density lipoprotein-cholesterol (HDL-C)...
  53. ncbi request reprint Ischemia-modified albumin in acute stroke
    Halim Abboud
    Department of Neurology and Stroke Center, Bichat University Hospital, Denis Diderot University and Medical School, Paris, France
    Cerebrovasc Dis 23:216-20. 2007
    ..Ischemia-modified albumin (IMA)is a new biological marker of ischemia. Previous studies have found increased serum IMA levels after myocardial ischemia, but no study has investigated the possibility that stroke modifies IMA blood levels...
  54. doi request reprint Classification of stroke subtypes
    P Amarenco
    Department of Neurology and Stroke Center, INSERM U 698 and Paris Diderot University, Bichat University Hospital, Paris, France
    Cerebrovasc Dis 27:493-501. 2009
    ..Parallel classifications (i.e. surrogate markers) may serve as within-study abnormalities to support research findings...
  55. ncbi request reprint Predictors for malignant middle cerebral artery infarctions: a postmortem analysis
    A Jaramillo
    APHP, Department of Neuropathology Raymond Escourolle, Salpetriere Hospital, Pierre and Marie Curie University, Paris, France
    Neurology 66:815-20. 2006
    ..Early detection of malignant infarction of the middle cerebral artery (MI-MCA) is important because of possible treatment by hemicraniectomy...
  56. ncbi request reprint Costs of stroke care according to handicap levels and stroke subtypes
    Jean François Spieler
    Institut National de la Santé et de la Recherche Médicale U 537 Economy of health, Paris, France
    Cerebrovasc Dis 17:134-42. 2004
    ..Our aim was to perform an in-depth evaluation of the direct medical cost of stroke care in a large cohort...
  57. doi request reprint Prevalence of embolic signals in acute coronary syndromes
    Elena Meseguer
    INSERM U 698 and Paris Diderot University, Bichat Hospital, Assistance Publique Hopitaux de Paris, Paris, France
    Stroke 41:261-6. 2010
    ..The purpose of this study was to assess the prevalence of embolic signals (ES) in acute coronary syndromes (ACS) and their association with stroke...
  58. ncbi request reprint Predictive values of lacunar transient ischemic attacks
    Dominique Herve
    Department of Neurology and Stroke Center, Bichat University Hospital and Medical School, Denis Diderot University, Paris, France
    Stroke 35:1430-5. 2004
    ....
  59. ncbi request reprint Blood pressure and lipid lowering in the prevention of stroke: a note to neurologists
    Pierre Amarenco
    Department of Neurology and Stroke Center, Bichat University Hospital and Medical School, 46 rue Henri Huchard, F 75018 Paris, France
    Cerebrovasc Dis 16:33-8. 2003
    ..It follows that rigorous identification and targeting of high- risk or stroke-prone individuals for blood pressure and lipid-lowering interventions should be of practical importance to all physicians involved in the management of stroke...
  60. doi request reprint Country-based reference values and impact of cardiovascular risk factors on carotid intima-media thickness in a French population: the 'Paroi Artérielle et Risque Cardio-Vasculaire' (PARC) Study
    Pierre Jean Touboul
    INSERM U 698, Paris, France
    Cerebrovasc Dis 27:361-7. 2009
    ..To define reference values for mean common carotid artery intima-media thickness (CCAIMT(mean)) from subjects without conventional cardiovascular risk factors...
  61. doi request reprint Underlying pathology of stroke of unknown cause (cryptogenic stroke)
    Pierre Amarenco
    INSERM U 698 and Paris Diderot University, Paris, France
    Cerebrovasc Dis 27:97-103. 2009
    ..g. arterial dissection, mobile intracardiac/luminal thrombus disappeared at the time of examination). In the next years, new diagnostic tools may hopefully determine which of these pathologies are or are not causally related to stroke...
  62. ncbi request reprint High blood pressure in early acute stroke: a sign of a poor outcome?
    Halim Abboud
    Department of Neurology and Stroke Centre, Bichat University Hospital and Medical School, Paris, France
    J Hypertens 24:381-6. 2006
    ..To evaluate the prognostic value of admission blood pressure in patients with acute ischemic stroke by determining whether it contributes to clinical outcome and vascular death...
  63. ncbi request reprint Prevalence and determinants of subdiaphragmatic visceral infarction in patients with fatal stroke
    Halim Abboud
    Assistance Publique Hopitaux de Paris, Paris, France
    Stroke 38:1442-6. 2007
    ..We therefore investigated the prevalence of SDVI in subjects who died from stroke. We also evaluated the yield of SDVI diagnosis for stroke subtyping...
  64. ncbi request reprint Association of small-vessel disease with dilatative arteriopathy of the brain: neuropathologic evidence
    Fernando Pico
    Department of Neuropathology Raymond Escourolle, AP HP Pitié Salpêtrière Hospital, Pierre et Marie Curie University, Paris, France
    Stroke 38:1197-202. 2007
    ..We used a large brain-autopsy collection to investigate the relation between IADE and pathologically assessed cerebral SVD...
  65. ncbi request reprint Flow-mediated vasodilatation of carotid and brachial arteries in healthy subjects and in lacunar stroke patients
    Philippa C Lavallee
    Department of Neurology and Stroke Centre, Bichat University Hospital and Medical School, Paris, France
    Ultrasound Med Biol 32:1165-9. 2006
    ..CCA vasodilatation induced by CO(2) inhalation and NTG administration can be measured. The strong negative correlation between CCA- and BA-FMVD suggests that there could be different mechanisms of vasodilatation...
  66. ncbi request reprint Adverse associations between CX3CR1 polymorphisms and risk of cardiovascular or cerebrovascular disease
    Elise Lavergne
    Laboratoire d Immunologie Cellulaire, INSERM U543, Hopital Pitie Salpetriere, Paris, France
    Arterioscler Thromb Vasc Biol 25:847-53. 2005
    ..We investigated the role of monocyte-recruiting chemokines in cerebrovascular diseases among the subjects of the GENIC case-control study of brain infarction (BI)...
  67. ncbi request reprint Correlation between the Framingham risk score and intima media thickness: the Paroi Artérielle et Risque Cardio-vasculaire (PARC) study
    Pierre Jean Touboul
    Department of Neurology and Stroke Center, Bichat Claude Bernard University Hospital and Medical School, Denis Diderot University Paris VII, Paris, France
    Atherosclerosis 192:363-9. 2007
    ....
  68. ncbi request reprint Cytokine polymorphisms associated with carotid intima-media thickness in stroke patients
    David Brenner
    Department of Neurology and Stroke Centre, Bichat University Hospital, Denis Diderot University and Medical School, Paris, France
    Stroke 37:1691-6. 2006
    ..Evidence exists that carotid IMT is heritable, and genetic studies can provide clues in the pathogenesis of atherosclerosis...
  69. ncbi request reprint Lipid lowering and recurrent stroke: another stroke paradox?
    Pierre Amarenco
    Eur Heart J 26:1818-9. 2005
  70. ncbi request reprint Randomized, double-blind, placebo-controlled, international trial of the oral IIb/IIIa antagonist lotrafiban in coronary and cerebrovascular disease
    Eric J Topol
    Department of Cardiovascular Medicine, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Circulation 108:399-406. 2003
    ....
  71. doi request reprint Antithrombotic and thrombolytic therapy for ischemic stroke: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition)
    Gregory W Albers
    Stanford University Medical Center, Stanford Stroke Center, 701 Welch Road, Palo Alto, CA 94304 1705, USA
    Chest 133:630S-669S. 2008
    ..5; range, 2.0 to 3.0) [Grade 1A]. In patients with venous sinus thrombosis, we recommend unfractionated heparin (Grade 1B) or low-molecular-weight heparin (Grade 1B) over no anticoagulant therapy during the acute phase...
  72. ncbi request reprint High-dose atorvastatin after stroke or transient ischemic attack
    Pierre Amarenco
    Denis Diderot University, Paris
    N Engl J Med 355:549-59. 2006
    ..Statins reduce the incidence of strokes among patients at increased risk for cardiovascular disease; whether they reduce the risk of stroke after a recent stroke or transient ischemic attack (TIA) remains to be established...
  73. doi request reprint Relative effects of statin therapy on stroke and cardiovascular events in men and women: secondary analysis of the Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL) Study
    Larry B Goldstein
    Duke University Medical Center, Durham, NC 27710, USA
    Stroke 39:2444-8. 2008
    ..9 years of follow-up. The purpose of this secondary analysis was to determine whether men and women similarly benefited from randomization to statin treatment...
  74. ncbi request reprint Prevention and health services delivery
    Larry B Goldstein
    Department of Medicine Neurology, Duke Center for Cerebrovascular Disease, Stroke Policy Program, Center for Clinical Health Policy Research, Duke University and Veterans Affairs Medical Center, Durham, NC 27710, USA
    Stroke 36:222-4. 2005
  75. doi request reprint EXPRESS transient ischemic attack study: speed the process!
    Pierre Amarenco
    INSERM U 698 and Denis Diderot University Paris VII, France
    Stroke 39:2400-1. 2008
  76. ncbi request reprint Stroke research priorities for the next decade--A representative view of the European scientific community
    Stephen Meairs
    Neurologische Klinik, Ruprecht Karls Universitat Heidelberg, Theodor Kutzer Ufer, DE 68135 Mannheim Germany
    Cerebrovasc Dis 22:75-82. 2006
  77. ncbi request reprint Myeloperoxidase polymorphisms in brain infarction. Association with infarct size and functional outcome
    Aline Hoy
    INSERM Unite 525 equipe 4, Centre de Medecine Preventive, 2 Avenue du Doyen Jacques Parisot, 54501 Vandoeuvre Les Nancy, Nancy, France
    Atherosclerosis 167:223-30. 2003
    ..02). In conclusion, MPO polymorphisms were associated with the extent of brain damage and the functional outcome rather than with the risk of developing a BI...
  78. doi request reprint Stroke is a coronary heart disease risk equivalent: implications for future clinical trials in secondary stroke prevention
    Pierre Amarenco
    INSERM U 698 and Denis Diderot University Paris VII, France
    Eur Heart J 29:1605-7. 2008
  79. ncbi request reprint New England Medical Center Posterior Circulation registry
    Louis R Caplan
    Cerebrovascular Disease Sections of the New England Medical Center, Boston, MA, USA
    Ann Neurol 56:389-98. 2004
    ..The best outcome was in patients who had multiple arterial occlusive sites; they had position-sensitive TIAs during months to years...
  80. ncbi request reprint Basilar artery diameter and 5-year mortality in patients with stroke
    Fernando Pico
    Department of Neurology, Mignot Versailles Hospital, Versailles
    Stroke 37:2342-7. 2006
    ..We analyzed basilar artery characteristics (diameter, height of bifurcation, transverse position) and 5-year mortality (all-cause, nonstroke vascular, and stroke) in patients with brain infarction...
  81. ncbi request reprint Intracranial arterial dolichoectasia and its relation with atherosclerosis and stroke subtype
    Fernando Pico
    Department of Neurology, Versailles Hospital, France
    Neurology 61:1736-42. 2003
    ..To investigate the relationship between intracranial arterial dolichoectasia (IADE) and vascular risk factors, atherosclerosis of the carotid arteries as measured by ultrasound scan, and stroke subtypes...
  82. ncbi request reprint Atheroma of the aortic arch: an important and poorly recognised factor in the aetiology of stroke
    Malcolm R Macleod
    Division of Clinical Neurosciences, University of Edinburgh, UK
    Lancet Neurol 3:408-14. 2004
    ..Here we review the evidence for aortic-arch atheroma as an important independent risk factor for stroke, and show that studies of the risk of stroke indicate a four times greater odds of stroke in patients with severe arch atheroma...
  83. ncbi request reprint [Transient ischemic attacks]
    Philippa Lavallée
    Service de Neurologie et Centre d Accueil et de Traitement de l Attaque Cérébrale, Hopital Bichat, Paris
    Presse Med 36:134-41. 2007
    ..Treatment by platelet aggregation inhibitors (aspirin 160-300 mg) should begin immediately and be adjusted according to test results...
  84. ncbi request reprint Statins for secondary stroke prevention in patients without known coronary heart disease: the jury is still out
    Larry B Goldstein
    Cerebrovasc Dis 18:1-2. 2004
  85. ncbi request reprint Antithrombotic and thrombolytic therapy for ischemic stroke: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy
    Gregory W Albers
    Stanford University Medical Center, Stanford Stroke Center, 701 Welch Rd, Building B, Suite 325, Palo Alto, CA 94304 1705, USA
    Chest 126:483S-512S. 2004
    ..5; range, 2.0 to 3.0) [Grade 1A]. In patients with venous sinus thrombosis, we recommend unfractionated heparin (Grade 1B) or low molecular weight heparin (Grade 1B) over no anticoagulant therapy during the acute phase...
  86. ncbi request reprint Prevention and health services delivery
    Larry B Goldstein
    Department of Medicine, Duke Center for Cerebrovascular Disease, Durham, NC 27710, USA
    Stroke 35:401-3. 2004
  87. ncbi request reprint Autopsy prevalence of coronary atherosclerosis in patients with fatal stroke
    Fernando Gongora-Rivera
    Department of Neuropathology Raymond Escourolle, La Salpetriere Hospital, France
    Stroke 38:1203-10. 2007
    ..The objective of the study was to establish the prevalence of coronary atherosclerosis and MI after fatal stroke...