Ghada Alsaleh

Summary

Country: France

Publications

  1. pmc Innate immunity triggers IL-32 expression by fibroblast-like synoviocytes in rheumatoid arthritis
    Ghada Alsaleh
    Université de Strasbourg, UFR Sciences Pharmaceutiques, 67401 Illkirch, France
    Arthritis Res Ther 12:R135. 2010
  2. doi request reprint MiR-20a regulates ASK1 expression and TLR4-dependent cytokine release in rheumatoid fibroblast-like synoviocytes
    Lucas Philippe
    ImmunoRhumatologie Moléculaire, INSERM UMR_S 1109, Universite de Strasbourg, Strasbourg, Cedex, France
    Ann Rheum Dis 72:1071-9. 2013
  3. doi request reprint TLR2 expression is regulated by microRNA miR-19 in rheumatoid fibroblast-like synoviocytes
    Lucas Philippe
    Unité de Formation et Recherche de Sciences Pharmaceutiques, Universite de Strasbourg, Illkirch Cedex, France
    J Immunol 188:454-61. 2012
  4. pmc miR-346 controls release of TNF-α protein and stability of its mRNA in rheumatoid arthritis via tristetraprolin stabilization
    Noha Semaan
    Laboratoire Physiopathologie des Arthrites, EA4438, Universite de Strasbourg, UFR Sciences Pharmaceutiques, Illkirch, France
    PLoS ONE 6:e19827. 2011
  5. doi request reprint Synovial fibroblasts promote immunoglobulin class switching by a mechanism involving BAFF
    Ghada Alsaleh
    Laboratoire Physiopathologie des Arthrites, Universite de Strasbourg, UFR Sciences Pharmaceutiques, Illkirch, France
    Eur J Immunol 41:2113-22. 2011
  6. pmc Microparticle-induced release of B-lymphocyte regulators by rheumatoid synoviocytes
    Laurent Messer
    Laboratoire Physiopathologie des Arthrites, Universite de Strasbourg, UFR Sciences Pharmaceutiques, Illkirch, France
    Arthritis Res Ther 11:R40. 2009
  7. pmc Deregulation of type I IFN-dependent genes correlates with increased susceptibility to cytomegalovirus acute infection of dicer mutant mice
    Eleonore Ostermann
    Universite de Strasbourg, EA 4438 Laboratoire d Immunogénétique Moléculaire Humaine, Strasbourg, France
    PLoS ONE 7:e43744. 2012

Collaborators

Detail Information

Publications7

  1. pmc Innate immunity triggers IL-32 expression by fibroblast-like synoviocytes in rheumatoid arthritis
    Ghada Alsaleh
    Université de Strasbourg, UFR Sciences Pharmaceutiques, 67401 Illkirch, France
    Arthritis Res Ther 12:R135. 2010
    ..We therefore investigated the effect of innate immune stimulation by ligands of Toll-like receptor (TLR)2, TLR3, and TLR4, and cytokines such as TNF-α and interferon (IFN)-γ, on IL-32 expression by FLSs...
  2. doi request reprint MiR-20a regulates ASK1 expression and TLR4-dependent cytokine release in rheumatoid fibroblast-like synoviocytes
    Lucas Philippe
    ImmunoRhumatologie Moléculaire, INSERM UMR_S 1109, Universite de Strasbourg, Strasbourg, Cedex, France
    Ann Rheum Dis 72:1071-9. 2013
    ....
  3. doi request reprint TLR2 expression is regulated by microRNA miR-19 in rheumatoid fibroblast-like synoviocytes
    Lucas Philippe
    Unité de Formation et Recherche de Sciences Pharmaceutiques, Universite de Strasbourg, Illkirch Cedex, France
    J Immunol 188:454-61. 2012
    ....
  4. pmc miR-346 controls release of TNF-α protein and stability of its mRNA in rheumatoid arthritis via tristetraprolin stabilization
    Noha Semaan
    Laboratoire Physiopathologie des Arthrites, EA4438, Universite de Strasbourg, UFR Sciences Pharmaceutiques, Illkirch, France
    PLoS ONE 6:e19827. 2011
    ..Conversely, transfection of miR-346 in LPS-activated THP-1 cells increased TTP mRNA expression and inhibited TNF-α release. These results indicate that miR-346 controls TNF-α synthesis by regulating TTP expression...
  5. doi request reprint Synovial fibroblasts promote immunoglobulin class switching by a mechanism involving BAFF
    Ghada Alsaleh
    Laboratoire Physiopathologie des Arthrites, Universite de Strasbourg, UFR Sciences Pharmaceutiques, Illkirch, France
    Eur J Immunol 41:2113-22. 2011
    ..Finally, we showed that the mechanism by which RA FLSs induce CSR is mostly BAFF-dependent. Our results support the hypothesis that CSR can be induced outside the ectopic lymphoid structures in RA...
  6. pmc Microparticle-induced release of B-lymphocyte regulators by rheumatoid synoviocytes
    Laurent Messer
    Laboratoire Physiopathologie des Arthrites, Universite de Strasbourg, UFR Sciences Pharmaceutiques, Illkirch, France
    Arthritis Res Ther 11:R40. 2009
    ....
  7. pmc Deregulation of type I IFN-dependent genes correlates with increased susceptibility to cytomegalovirus acute infection of dicer mutant mice
    Eleonore Ostermann
    Universite de Strasbourg, EA 4438 Laboratoire d Immunogénétique Moléculaire Humaine, Strasbourg, France
    PLoS ONE 7:e43744. 2012
    ..In addition, our in vivo efforts identified several miRNA targets, thus providing a conceptual framework for future analyzes on the regulation of specific actors involved in the Type I interferon pathway...