Y Allanore

Summary

Country: France

Publications

  1. pmc Erectile dysfunction is frequent in systemic sclerosis and associated with severe disease: a study of the EULAR Scleroderma Trial and Research group
    Chingching Foocharoen
    Department of Rheumatology, Basel University, Burgfelderstrasse 101, Basel 4012, Switzerland
    Arthritis Res Ther 14:R37. 2012
  2. ncbi request reprint Multiple spontaneous visceral hematomas revealing polyarteritis nodosa
    Yannick Allanore
    Paris V University, Departments of Rheumatology and Radiology Assistance Publique Hopitaux de Paris, Cochin Hospital, Paris, France
    J Rheumatol 31:1858-60. 2004
  3. pmc Effects of corticosteroids and immunosuppressors on idiopathic inflammatory myopathy related myocarditis evaluated by magnetic resonance imaging
    Y Allanore
    Service de Rhumatologie A, Hopital Cochin, 27 rue du Faubourg Saint Jacques, 75014 Paris, France
    Ann Rheum Dis 65:249-52. 2006
  4. pmc Nifedipine protects against overproduction of superoxide anion by monocytes from patients with systemic sclerosis
    Yannick Allanore
    Rheumatology A Department, Paris V University, Assistance Publique Hopitaux de Paris, Cochin Hospital, Paris, France
    Arthritis Res Ther 7:R93-100. 2005
  5. ncbi request reprint Induction of autoantibodies in refractory rheumatoid arthritis treated by infliximab
    Y Allanore
    Rheumatology A Department, Paris V University, Cochin Hospital, AP HP Paris, France
    Clin Exp Rheumatol 22:756-8. 2004
  6. ncbi request reprint Lack of association of eNOS (G894T) and p22phox NADPH oxidase subunit (C242T) polymorphisms with systemic sclerosis in a cohort of French Caucasian patients
    Yannick Allanore
    Department of Rheumatology A, Assistance Publique Hopitaux de Paris, Cochin Hospital, Paris V University, 75679 Paris Cedex 14, France
    Clin Chim Acta 350:51-5. 2004
  7. pmc Increased prevalence of ocular glaucomatous abnormalities in systemic sclerosis
    Y Allanore
    Hopital Cochin, Service de Rhumatologie A, 27 rue du Faubourg Saint Jacques, 75014 Paris, France
    Ann Rheum Dis 63:1276-8. 2004
  8. pmc Nifedipine decreases sVCAM-1 concentrations and oxidative stress in systemic sclerosis but does not affect the concentrations of vascular endothelial growth factor or its soluble receptor 1
    Yannick Allanore
    Paris V University, Department of Rheumatology A, Assistance Publique Hopitaux de Paris, Cochin Hospital, Paris, France
    Arthritis Res Ther 6:R309-14. 2004
  9. ncbi request reprint N-terminal pro-brain natriuretic peptide as a diagnostic marker of early pulmonary artery hypertension in patients with systemic sclerosis and effects of calcium-channel blockers
    Y Allanore
    Paris V University, Assistance Publique Hopitaux de Paris, Hopital Cochin, Paris, France
    Arthritis Rheum 48:3503-8. 2003
  10. ncbi request reprint Sacral inflammatory pseudotumor revealed by paraneoplastic syndrome
    Y Allanore
    Department of Rheumatology, Assistance Publique Hopitaux de Paris, Rene Descartes University, Paris, France
    Rheumatol Int 24:166-8. 2004

Detail Information

Publications111 found, 100 shown here

  1. pmc Erectile dysfunction is frequent in systemic sclerosis and associated with severe disease: a study of the EULAR Scleroderma Trial and Research group
    Chingching Foocharoen
    Department of Rheumatology, Basel University, Burgfelderstrasse 101, Basel 4012, Switzerland
    Arthritis Res Ther 14:R37. 2012
    ..Erectile dysfunction (ED) is common in men with systemic sclerosis (SSc) but the demographics, risk factors and treatment coverage for ED are not well known...
  2. ncbi request reprint Multiple spontaneous visceral hematomas revealing polyarteritis nodosa
    Yannick Allanore
    Paris V University, Departments of Rheumatology and Radiology Assistance Publique Hopitaux de Paris, Cochin Hospital, Paris, France
    J Rheumatol 31:1858-60. 2004
    ..Arteriography was performed for a recent spontaneous hepatic hematoma and a microaneurysm was detected, allowing the diagnosis of polyarteritis nodosa and prescription of appropriate treatment...
  3. pmc Effects of corticosteroids and immunosuppressors on idiopathic inflammatory myopathy related myocarditis evaluated by magnetic resonance imaging
    Y Allanore
    Service de Rhumatologie A, Hopital Cochin, 27 rue du Faubourg Saint Jacques, 75014 Paris, France
    Ann Rheum Dis 65:249-52. 2006
    ..Cardiac involvement in idiopathic inflammatory myopathy has been recognised as an important prognostic factor, but treatment remains empirical...
  4. pmc Nifedipine protects against overproduction of superoxide anion by monocytes from patients with systemic sclerosis
    Yannick Allanore
    Rheumatology A Department, Paris V University, Assistance Publique Hopitaux de Paris, Cochin Hospital, Paris, France
    Arthritis Res Ther 7:R93-100. 2005
    ..This supports the hypothesis that this drug could be useful for the treatment of diseases associated with oxidative stress...
  5. ncbi request reprint Induction of autoantibodies in refractory rheumatoid arthritis treated by infliximab
    Y Allanore
    Rheumatology A Department, Paris V University, Cochin Hospital, AP HP Paris, France
    Clin Exp Rheumatol 22:756-8. 2004
    ..To investigate autoantibody induction in rheumatoid arthritis (RA) patients treated with infliximab...
  6. ncbi request reprint Lack of association of eNOS (G894T) and p22phox NADPH oxidase subunit (C242T) polymorphisms with systemic sclerosis in a cohort of French Caucasian patients
    Yannick Allanore
    Department of Rheumatology A, Assistance Publique Hopitaux de Paris, Cochin Hospital, Paris V University, 75679 Paris Cedex 14, France
    Clin Chim Acta 350:51-5. 2004
    ..To assess the influence of endothelial nitric oxide synthase (eNOS) and nicotinamide adenine dinucleotide phosphate (NADPH) oxidase polymorphisms on the susceptibility of patients to and clinical expression of systemic sclerosis (SSc)...
  7. pmc Increased prevalence of ocular glaucomatous abnormalities in systemic sclerosis
    Y Allanore
    Hopital Cochin, Service de Rhumatologie A, 27 rue du Faubourg Saint Jacques, 75014 Paris, France
    Ann Rheum Dis 63:1276-8. 2004
    ..Cardiovascular diseases, vasospasm, and dysimmunity have been implicated in normal tension glaucoma (NTG)...
  8. pmc Nifedipine decreases sVCAM-1 concentrations and oxidative stress in systemic sclerosis but does not affect the concentrations of vascular endothelial growth factor or its soluble receptor 1
    Yannick Allanore
    Paris V University, Department of Rheumatology A, Assistance Publique Hopitaux de Paris, Cochin Hospital, Paris, France
    Arthritis Res Ther 6:R309-14. 2004
    ..However, more experimental evidence is needed to determine whether the VEGF pathway is intrinsically defective in SSc...
  9. ncbi request reprint N-terminal pro-brain natriuretic peptide as a diagnostic marker of early pulmonary artery hypertension in patients with systemic sclerosis and effects of calcium-channel blockers
    Y Allanore
    Paris V University, Assistance Publique Hopitaux de Paris, Hopital Cochin, Paris, France
    Arthritis Rheum 48:3503-8. 2003
    ....
  10. ncbi request reprint Sacral inflammatory pseudotumor revealed by paraneoplastic syndrome
    Y Allanore
    Department of Rheumatology, Assistance Publique Hopitaux de Paris, Rene Descartes University, Paris, France
    Rheumatol Int 24:166-8. 2004
    ..All clinical symptoms disappeared within a few days after surgery, which is suggestive of a paraneoplastic syndrome. No relapse has occurred after 4 years...
  11. ncbi request reprint Brachial plexopathy associated with systemic sclerosis
    Y Allanore
    Cochin Hospital, Assistance Publique Hopitaux de Paris, Rene Descartes University, France
    Clin Rheumatol 21:401-2. 2002
    ..We report a third case of brachial plexopathy, presumably related to vasculitis, in a patient with systemic sclerosis, which improved after cyclophosphamide therapy...
  12. ncbi request reprint [Psoriatic arthritis]
    Y Allanore
    Service de Rhumatologie A, Pr Kahan, Hopital Cochin, AP HP, Universite Paris V, 27, rue du Faubourg Saint Jacques 75014 Paris
    Ann Dermatol Venereol 129:1401-4. 2002
  13. doi request reprint Association between the IRF5 rs2004640 functional polymorphism and systemic sclerosis: a new perspective for pulmonary fibrosis
    P Dieude
    Universite Paris 7, and Hôpital Bichat Claude Bernard, Assistance Publique Hopitaux de Paris, Paris, France
    Arthritis Rheum 60:225-33. 2009
    ..The aim of this study was to determine whether the IRF5 rs2004640 single-nucleotide polymorphism is associated with SSc...
  14. doi request reprint BANK1 is a genetic risk factor for diffuse cutaneous systemic sclerosis and has additive effects with IRF5 and STAT4
    P Dieude
    Universite Paris 7 Denis Diderot, Hopital Bichat Claude Bernard, Assistance Publique Hopitaux de Paris AP HP, Paris, France
    Arthritis Rheum 60:3447-54. 2009
    ....
  15. doi request reprint High N-terminal pro-brain natriuretic peptide levels and low diffusing capacity for carbon monoxide as independent predictors of the occurrence of precapillary pulmonary arterial hypertension in patients with systemic sclerosis
    Y Allanore
    Rene Descartes University, Cochin Hospital, Assistance Publique Hopitaux de Paris, Paris, France
    Arthritis Rheum 58:284-91. 2008
    ..To evaluate predictors of pulmonary arterial hypertension (PAH) in a prospective cohort of patients with systemic sclerosis (SSc)...
  16. ncbi request reprint Disturbed angiogenesis in systemic sclerosis: high levels of soluble endoglin
    J Wipff
    Department of Rheumatology A, Paris Descartes University, Medical Faculty, Cochin Hospital, Paris, France
    Rheumatology (Oxford) 47:972-5. 2008
    ..The aim of this study was to investigate, in a cross-sectional study, sENG levels together with other serum vascular markers...
  17. doi request reprint STAT4 is a genetic risk factor for systemic sclerosis having additive effects with IRF5 on disease susceptibility and related pulmonary fibrosis
    P Dieude
    Université Paris 7 and Service de Rhumatologie, Hopital Bichat Claude Bernard, Assistance Publique Hopitaux de Paris, Paris, France
    Arthritis Rheum 60:2472-9. 2009
    ..The aim of this study was to determine whether the STAT4 rs7574865 single-nucleotide polymorphism is associated with SSc, and whether it interacts with IRF5...
  18. doi request reprint Association of hypoxia-inducible factor 1A (HIF1A) gene polymorphisms with systemic sclerosis in a French European Caucasian population
    J Wipff
    Rene Descartes University, Department of Rheumatology A, Cochin Hospital, Paris
    Scand J Rheumatol 38:291-4. 2009
    ..The aim of this study was to determine whether polymorphisms of the hypoxia-inducible factor 1A gene (HIF1A) affects susceptibility to SSc in a large French European Caucasian population...
  19. doi request reprint Angiogenesis in systemic sclerosis: impaired expression of vascular endothelial growth factor receptor 1 in endothelial progenitor-derived cells under hypoxic conditions
    J Avouac
    Université Paris Descartes and Hôpital Cochin, Assistance Publique Hopitaux de Paris, Paris, and INSERM U781, Hopital Necker, Paris, France
    Arthritis Rheum 58:3550-61. 2008
    ..To assess angiogenesis and explore the expression and regulation of vascular endothelial growth factor (VEGF), VEGF receptor 1 (VEGFR-1), and VEGFR-2, the leading mediators of angiogenesis, in SSc patients and controls...
  20. doi request reprint Myopathies related to systemic sclerosis: a case-control study of associated clinical and immunological features
    B Ranque
    Department of Internal Medicine, French National Reference Center for Systemic Sclerosis and Necrotizing Vasculitides, Cochin Hospital, Faculty of Medicine, Paris Descartes University, the Public Assistance Hospitals of Paris AH HP, France
    Scand J Rheumatol 39:498-505. 2010
    ..Little is known about systemic sclerosis (SSc)-related myopathy. We aimed to compare the clinical and immunological features of SSc patients with or without associated myopathy...
  21. ncbi request reprint [Inducible nitric oxide synthase expression and nitric oxide production by monocytes in systemic sclerosis]
    C J Menkes
    Service de Rhumatologie A, Hopital Cochin, 27 rue du Faubourg Saint Jacques 75679 Paris
    Bull Acad Natl Med 185:509-22; discussion 522-3. 2001
    ..Low levels of NO, a vasodilator, may be involved in vasospasm, which is critical in SSc. This may suggest therapeutic implications...
  22. doi request reprint The PTPN22 620W allele confers susceptibility to systemic sclerosis: findings of a large case-control study of European Caucasians and a meta-analysis
    P Dieude
    Universite Paris 7, Paris, France
    Arthritis Rheum 58:2183-8. 2008
    ..We then conducted a meta-analysis of the most recent studies of SSc in order to verify the association or lack of association between the PTPN22 1858C>T variant and SSc...
  23. ncbi request reprint Levels of circulating endothelial progenitor cells in systemic sclerosis
    Y Allanore
    Rheumatology A and Immunology departments, Rene Descartes University, Medical School, Cochin Hospital, Assistance Publique Hopitaux de Paris, France
    Clin Exp Rheumatol 25:60-6. 2007
    ..Our aim was to investigate bone marrow-derived circulating endothelial precursors (EPCs) and activated circulating endothelial cells (CECs) in SSc patients...
  24. doi request reprint Association of a KCNA5 gene polymorphism with systemic sclerosis-associated pulmonary arterial hypertension in the European Caucasian population
    J Wipff
    Universite Paris Descartes, INSERM U781, Hopital Necker, and Hôpital Cochin, Paris, France
    Arthritis Rheum 62:3093-100. 2010
    ..We undertook this study to determine whether KCNA5 polymorphisms confer susceptibility to SSc and its vascular phenotype, including PAH...
  25. doi request reprint N-terminal pro-brain natriuretic peptide in systemic sclerosis: a new cornerstone of cardiovascular assessment?
    Y Allanore
    Department of Rheumatology A, Paris Descartes University, Cochin Hospital, APHP, 75014 Paris, France
    Ann Rheum Dis 68:1885-9. 2009
    ..Cardiac involvement, a common and often fatal complication of systemic sclerosis (SSc), is currently detected by standard echocardiography enhanced by tissue Doppler echocardiography (TDE)...
  26. doi request reprint Prevalence and factors associated with left ventricular dysfunction in the EULAR Scleroderma Trial and Research group (EUSTAR) database of patients with systemic sclerosis
    Y Allanore
    Service de Rhumatologie A, Hopital Cochin, Universite Paris Descartes, 27 rue du Faubourg Saint Jacques, 75014 Paris, France
    Ann Rheum Dis 69:218-21. 2010
    ..To measure the prevalence of, and factors associated with, left ventricular (LV) dysfunction in systemic sclerosis (SSc)...
  27. ncbi request reprint Serum protein oxidation in patients with rheumatoid arthritis and effects of infliximab therapy
    H Lemarechal
    Department of Biochemistry A, Assistance Publique Hopitaux de Paris, Cochin Hospital, 75014 Paris, France
    Clin Chim Acta 372:147-53. 2006
    ..To examine protein oxidation in rheumatoid arthritis (RA) and evaluate its evolution after infliximab therapy in a subgroup of patients...
  28. doi request reprint Association of the CD226 Ser(307) variant with systemic sclerosis: evidence of a contribution of costimulation pathways in systemic sclerosis pathogenesis
    P Dieude
    Universite Paris Diderot, Hopital Bichat Claude Bernard, Paris, France
    Arthritis Rheum 63:1097-105. 2011
    ..The purpose of this study was to test for association of the CD226 rs763361 polymorphism with systemic sclerosis (SSc) in European Caucasian populations...
  29. ncbi request reprint Association between an endoglin gene polymorphism and systemic sclerosis-related pulmonary arterial hypertension
    J Wipff
    Rene Descartes University, Medical Faculty, Rheumatology A Department, Cochin Hospital, AP HP, Paris, France
    Rheumatology (Oxford) 46:622-5. 2007
    ..A 6-base insertion in intron 7 (6bINS) of ENG has been reported to be associated with microvascular disturbance...
  30. pmc Radiological hand involvement in systemic sclerosis
    J Avouac
    Service de Rhumatologie A, Hopital Cochin, 27 rue du Faubourg Saint Jacques, 75014 Paris, France
    Ann Rheum Dis 65:1088-92. 2006
    ..The osteoarticular and soft tissue structures of the hand may be involved in systemic sclerosis (SSc), causing functional disability...
  31. doi request reprint Circulating endothelial progenitor cells in systemic sclerosis: association with disease severity
    J Avouac
    Paris Descartes University, Rheumatology A Department, Cochin Hospital, APHP, Paris, France
    Ann Rheum Dis 67:1455-60. 2008
    ..Heterogeneous data have been reported regarding the detection and number of circulating endothelial progenitor cells (EPCs) in systemic sclerosis (SSc)...
  32. ncbi request reprint Low levels of nitric oxide (NO) in systemic sclerosis: inducible NO synthase production is decreased in cultured peripheral blood monocyte/macrophage cells
    Y Allanore
    Department of Rheumatology A, Cochin Hospital, , Paris 75014, France
    Rheumatology (Oxford) 40:1089-96. 2001
    ..Low levels of NO, a vasodilator, may be involved in vasospasm, which is critical in SSc. This may have therapeutic implications...
  33. doi request reprint Evidence of the contribution of the X chromosome to systemic sclerosis susceptibility: association with the functional IRAK1 196Phe/532Ser haplotype
    P Dieude
    Paris Diderot University, AP HP, INSERM U699, Paris, France
    Arthritis Rheum 63:3979-87. 2011
    ..This study was undertaken to test for an association between SSc and the IRAK1 SLE risk haplotype...
  34. pmc Lack of association between three vascular endothelial growth factor gene polymorphisms and systemic sclerosis: results from a multicenter EUSTAR study of European Caucasian patients
    Y Allanore
    Hopital Cochin, Service de Rhumatologie A, 27 rue du Faubourg Saint Jacques, 75014 Paris, France
    Ann Rheum Dis 66:257-9. 2007
    ..Systemic sclerosis (SSc) is characterised by disturbed vessel morphology and an overproduction of vascular endothelial growth factor (VEGF). The VEGF gene located on chromosome 6p21.3 has several polymorphisms...
  35. pmc Increased plasma soluble CD40 ligand concentrations in systemic sclerosis and association with pulmonary arterial hypertension and digital ulcers
    Y Allanore
    Rheumatology A, Paris V University, Assistance Publique Hopitaux de Paris, France
    Ann Rheum Dis 64:481-3. 2005
    ..Increased expression of CD40L has been reported on activated CD4+ T lymphocytes in systemic sclerosis. CD40L can be expressed in soluble form (sCD40L)...
  36. doi request reprint Predictive factors of hand radiographic lesions in systemic sclerosis: a prospective study
    J Avouac
    Hopital Cochin, Service de Rhumatologie A, 27 rue du Faubourg Saint Jacques, 75014 Paris, France
    Ann Rheum Dis 70:630-3. 2011
    ..To examine the outcomes of hand radiographic x-rays in patients with systemic sclerosis (SSc) and to identify risk factors for the progression of hand radiographic lesions in a prospective cohort...
  37. doi request reprint Prognostic factors for lung function in systemic sclerosis: prospective study of 105 cases
    M Gilson
    Dept of Rheumatology A, Paris Descartes University, Cochin Hospital, Paris, France
    Eur Respir J 35:112-7. 2010
    ..Only diffuse SSc was predictive of a decrease in pulmonary function in this early-SSc cohort. This does not support preliminary data suggestive of a causative role of oesophageal involvement...
  38. ncbi request reprint Hand vascular involvement assessed by magnetic resonance angiography in systemic sclerosis
    Y Allanore
    Rene Descartes University, and Service de Rheumatologie A, Hopital Cochin, 27 rue du Faubourg St Jacques, 75014 Paris, France
    Arthritis Rheum 56:2747-54. 2007
    ..Magnetic resonance angiography (MRA) has improved the assessment of vascular lesions of the hand. The aim of this study was to evaluate vascular abnormalities in the hands of patients with SSc, using MRA...
  39. ncbi request reprint N-terminal pro brain natriuretic peptide: the new cornerstone of cardiovascular assessment in systemic sclerosis
    Y Allanore
    Department of Rheumatology A, Cochin Hospital, Paris Descartes University, Paris, France
    Clin Exp Rheumatol 27:59-63. 2009
    ....
  40. pmc Risk of tuberculosis is higher with anti-tumor necrosis factor monoclonal antibody therapy than with soluble tumor necrosis factor receptor therapy: The three-year prospective French Research Axed on Tolerance of Biotherapies registry
    F Tubach
    Universite Paris 7 Denis Diderot, INSERM U738, Assistance Publique Hopitaux de Paris AP HP, Hopital Bichat, Biostatistique et Recherche Clinique, Paris, France
    Arthritis Rheum 60:1884-94. 2009
    ..Our objective was to describe cases of TB associated with anti-TNF mAb therapy, identify risk factors, and estimate the incidence...
  41. pmc Evaluation of the effect of nifedipine upon myocardial perfusion and contractility using cardiac magnetic resonance imaging and tissue Doppler echocardiography in systemic sclerosis
    O Vignaux
    Services de Radiologie A, Hopital Cochin, AP HP, Universite Paris V, 75014 Paris, France
    Ann Rheum Dis 64:1268-73. 2005
    ..Previous studies have suggested that dihydropyridine-type calcium channel blockers mitigate both myocardial perfusion and function abnormalities...
  42. ncbi request reprint Prevalence of antiphospholipid antibodies in systemic sclerosis and association with primitive pulmonary arterial hypertension and endothelial injury
    N Assous
    Department of Rheumatology A, Paris 5 University, Assistance Publique Hopitaux de Paris, Cochin Hospital, Paris, France
    Clin Exp Rheumatol 23:199-204. 2005
    ..To investigate the prevalence and clinical significance of antiphospholipid antibodies in patients with systemic sclerosis (SSc)...
  43. pmc Lack of association between the protein tyrosine phosphatase non-receptor 22 (PTPN22)*620W allele and systemic sclerosis in the French Caucasian population
    J Wipff
    Rheumatology A Department, Cochin Hospital, Paris, France
    Ann Rheum Dis 65:1230-2. 2006
    ..38). The PTPN22*620W allele was also not associated with autoantibody patterns. Thus, the PTPN22*R620W polymorphism cannot be regarded as a genetic susceptibility factor for SSc in the French Caucasian population...
  44. ncbi request reprint [Spondylarthropathies and anti-TNFalpha drugs]
    S Pavy
    Service de Rhumatologie A, Universite Paris 5, Hopital Cochin, 27, rue du Faubourg Saint Jacques, AP HP, 75014 Paris, France
    Rev Med Interne 26:717-24. 2005
    ..TNFalpha appears as an important actor in the pathogenesis of spondylarthropathies...
  45. ncbi request reprint Primary myocardial involvement in systemic sclerosis: evidence for a microvascular origin
    Y Allanore
    Paris Descartes University, Department of Rheumatology, Cochin Hospital, Paris, France
    Clin Exp Rheumatol 28:S48-53. 2010
    ..Recent quantitative methods such as tissue Doppler echocardiography and magnetic resonance imaging have underlined these results...
  46. doi request reprint Cardiovascular risk in rheumatoid arthritis: effects of anti-TNF drugs
    J Avouac
    Paris Descartes University, Medical Faculty, Department of Rheumatology A, Cochin Hospital, AP HP, Paris, France
    Expert Opin Pharmacother 9:1121-8. 2008
    ....
  47. doi request reprint Outcome measures for heart involvement in systemic sclerosis
    Y Allanore
    Department of Rheumatology A, Paris Descartes University, Cochin Hospital, AP HP, Paris, France
    Rheumatology (Oxford) 47:v51-3. 2008
    ..Their predictive value should also be investigated when there is primary heart involvement...
  48. ncbi request reprint Systemic sclerosis-associated Sjögren's syndrome and relationship to the limited cutaneous subtype: results of a prospective study of sicca syndrome in 133 consecutive patients
    J Avouac
    Rene Descartes University, Medical Faculty, Hopital Cochin, France
    Arthritis Rheum 54:2243-9. 2006
    ..To determine the prevalence of sicca symptoms and Sjögren's syndrome (SS) in a 2-center prospective series of patients with systemic sclerosis (SSc), using the American-European Consensus Group criteria for SS...
  49. doi request reprint A descriptive and prognostic study of systemic sclerosis-associated myopathies
    B Ranque
    Universite Paris Descartes, UPRES EA 4058, Department of Internal Medicine, French National Reference Center for Systemic Sclerosis and Necrotizing Vasculitides, Hopital Cochin, Assistance Publique des Hopitaux de Paris, Paris, France
    Ann Rheum Dis 68:1474-7. 2009
    ..To describe the clinical characteristics and muscle pathological features of patients with systemic sclerosis (SSc) and myopathy and analyse their impact on muscle outcome...
  50. ncbi request reprint Effects of oral treatments on exercise capacity in systemic sclerosis related pulmonary arterial hypertension: a meta-analysis of randomised controlled trials
    J Avouac
    Paris Descartes University, Rheumatology A Department, Cochin Hospital, APHP, Paris, France
    Ann Rheum Dis 67:808-14. 2008
    ....
  51. ncbi request reprint [Heart involvement in systemic sclerosis]
    Yannick Allanore
    Universite Rene Descartes, Faculte de Medicine, Service de Rhumatologie A, Hopital Cochin, AP HP, Paris
    Presse Med 35:1938-42. 2006
    ..Treatment for myocardial involvement includes long-term systematic administration of calcium channel blockers and possibly angiotensin-converting enzyme inhibitors, frequently given at high dosage...
  52. ncbi request reprint Management of a patient with sarcoid calcaneitis and dactylitis
    Y Allanore
    , Service de Rhumatologie A, H pital Cochin, France
    Joint Bone Spine 68:175-7. 2001
    ..Involvement of the calcaneus is exceedingly rare, and its treatment is not standardized. In our patient, glucocorticoid therapy combined with methotrexate and hydroxychloroquine were effective in controlling the disease...
  53. doi request reprint [Watermelon stomach in systemic sclerosis]
    K Laoubi
    Service de Rhumatologie A, Hopital Cochin, Universite Paris Descartes, 27, rue du Faubourg Saint Jacques, 75014 Paris, France
    J Mal Vasc 35:250-3. 2010
    ..Indeed, specific local treatment must be delivered and is usually efficient despite frequent recurrent events...
  54. ncbi request reprint Primary myocardial involvement in systemic sclerosis
    A Kahan
    Paris 5 René Descartes University, Department of Rheumatology A, Cochin Hospital, AP HP, Paris, France
    Rheumatology (Oxford) 45:iv14-7. 2006
    ..Vasodilators, such as calcium channel blockers and angiotensin converting enzyme inhibitors, improve both myocardial perfusion and function abnormalities...
  55. doi request reprint Immunogenetics of systemic sclerosis
    P Dieude
    Universite Paris Diderot, Service de Rhumatologie, Hopital Bichat Claude Bernard, APHP, Paris, France
    Autoimmun Rev 10:282-90. 2011
    ....
  56. doi request reprint Heart involvement in systemic sclerosis: evolving concept and diagnostic methodologies
    Christophe Meune
    Service de cardiologie, Hopital Cochin, AP HP, Universite Paris Descartes, 27, rue du Faubourg Saint Jacques, 75014 Paris, France
    Arch Cardiovasc Dis 103:46-52. 2010
    ..Biological variables, such as B-type natriuretic peptides, are highly relevant, valuable markers of global heart involvement in systemic sclerosis and should be considered for screening of patients and/or research purposes...
  57. ncbi request reprint Myocardial contractility is early affected in systemic sclerosis: a tissue Doppler echocardiography study
    Christophe Meune
    Department of Cardiology, Cochin Hospital, AP HP, Rene Descartes University, 27 rue du Fg St Jacques, 75014 Paris, France
    Eur J Echocardiogr 6:351-7. 2005
    ..Our aim was to prospectively investigate LV function in SSc patients, using Tissue Doppler echocardiography (TDE), a modern and accurate method of assessing myocardial function...
  58. ncbi request reprint High ischemia-modified albumin concentration reflects oxidative stress but not myocardial involvement in systemic sclerosis
    Didier Borderie
    Departments of Biochemistry A, Paris V University, Assistance Publique Hopitaux de Paris, Cochin Hospital, Paris, France
    Clin Chem 50:2190-3. 2004
  59. ncbi request reprint Correlation of serum collagen I carboxyterminal telopeptide concentrations with cutaneous and pulmonary involvement in systemic sclerosis
    Yannick Allanore
    Department of Rheumatology A, Paris V University, France
    J Rheumatol 30:68-73. 2003
    ..Type I collagen (Col I) is the most abundant extracellular matrix protein deposited in cutaneous involvement. We investigated Col I biochemical markers in patients with SSc...
  60. doi request reprint Association of Fcγ receptor IIIA variant with a subset of anti-topoisomerase I-positive patients in systemic sclerosis: a descriptive pilot study
    J Magnant
    Service de Médecine Interne et Vasculaire B, CHRU de Tours, France, Tours, France
    Rheumatol Int 32:2203-7. 2012
    ..SSc patients with anti-topo I appear to be more frequently homozygous for the high-affinity FcγRIIIA-coding allele, suggesting that some autoantibodies may be pathogenic through ADCC...
  61. ncbi request reprint [Treatment of systemic scleroderma: update]
    Y Allanore
    Service de Rhumatologie A, Universite Paris 5, Faculte de Medecine, Hopital Cochin, Assistance Publique Hopitaux de Paris, 75014 Paris
    Ann Dermatol Venereol 133:286-91. 2006
  62. ncbi request reprint Prevalence of Barrett's esophagus in systemic sclerosis
    J Wipff
    Cochin Hospital, AP HP Paris 5 University, Paris, France
    Arthritis Rheum 52:2882-8. 2005
    ..This study sought to determine the prevalence of BE and esophageal adenocarcinoma in a cohort of SSc patients...
  63. ncbi request reprint Acute and sustained effects of dihydropyridine-type calcium channel antagonists on oxidative stress in systemic sclerosis
    Yannick Allanore
    Rheumatology A Departments, Paris V University, Assistance Publique Hopitaux de Paris, Cochin Hospital, Paris, France
    Am J Med 116:595-600. 2004
    ..To evaluate the potential antioxidant properties of dihydropyridine calcium channel antagonists in systemic sclerosis...
  64. ncbi request reprint Cardiac involvement in systemic sclerosis assessed by tissue-doppler echocardiography during routine care: A controlled study of 100 consecutive patients
    Christophe Meune
    Hopital Cochin, Universite Paris Descartes, Assistance Publique Hopitaux de Paris, Paris, France
    Arthritis Rheum 58:1803-9. 2008
    ..To assess the prevalence of primary cardiac complications in a large population of patients with systemic sclerosis (SSc), using recently developed echocardiographic techniques...
  65. doi request reprint Associated autoimmune diseases in systemic sclerosis define a subset of patients with milder disease: results from 2 large cohorts of European Caucasian patients
    Jerome Avouac
    Rheumatology A Department, Paris Descartes University, Cochin Hospital, Paris, France
    J Rheumatol 37:608-14. 2010
    ..To assess the prevalence and potential associations with the systemic sclerosis (SSc) phenotype of additional autoimmune diseases (AID)...
  66. ncbi request reprint Bosentan increases myocardial perfusion and function in systemic sclerosis: a magnetic resonance imaging and Tissue-Doppler echography study
    Yannick Allanore
    Services de Rhumatologie A, Cardiologie, and Radiologie A, Universite Paris Descartes, Faculte de Medecine, Hopital Cochin, Paris, France
    J Rheumatol 33:2464-9. 2006
    ..To evaluate the short-term effects of bosentan on myocardial perfusion and function assessed by cardiac magnetic resonance imaging (MRI) and Tissue-Doppler echography (TDE) respectively in patients with systemic sclerosis (SSc)...
  67. ncbi request reprint High prevalence of right ventricular systolic dysfunction in early systemic sclerosis
    Christophe Meune
    Department of Cardiology, Cochin Hospital, APHP, Paris V University, Paris, France
    J Rheumatol 31:1941-5. 2004
    ..To assess right ventricular (RV) function in patients with early systemic sclerosis (SSc) and the acute effects of calcium channel blockers on RV ejection fraction (RVEF)...
  68. ncbi request reprint Cardiovascular disease in rheumatoid arthritis: single-center hospital-based cohort study in France
    Noémie Assous
    Rheumatology A Department, School of Medicine, Rene Descartes University, Cochin Teaching Hospital, Paris, France
    Joint Bone Spine 74:66-72. 2007
    ..Rheumatoid arthritis (RA) was independently associated with cardiovascular events in several studies, most of which were conducted in the US...
  69. doi request reprint Preliminary criteria for the very early diagnosis of systemic sclerosis: results of a Delphi Consensus Study from EULAR Scleroderma Trials and Research Group
    J Avouac
    Rheumatology A Department, Cochin Hospital, 27 rue du Faubourg Saint Jacques, 75014 Paris, France
    Ann Rheum Dis 70:476-81. 2011
    ..To identify a core set of preliminary items considered as important for the very early diagnosis of systemic sclerosis (SSc)...
  70. doi request reprint Phenotype-haplotype correlation of IRF5 in systemic sclerosis: role of 2 haplotypes in disease severity
    Philippe Dieude
    Service de Rhumatologie, Hopital Bichat Claude Bernard, APHP, Université Diderot Paris 7, Paris, France
    J Rheumatol 37:987-92. 2010
    ..Our aim was to investigate whether IRF5 haplotypes confer susceptibility to SSc, and to perform genotype haplotype-phenotype correlation analyses...
  71. doi request reprint Angiotensin-converting enzyme gene does not contribute to genetic susceptibility to systemic sclerosis in European Caucasians
    Julien Wipff
    Paris Descartes Université, Rhumatologie A, Hopital Cochin, AP HP, Paris, France
    J Rheumatol 36:337-40. 2009
    ..To determine whether angiotensin-converting enzyme (ACE) polymorphisms including I/D and 2 single-nucleotide polymorphisms (SNP) affect susceptibility to systemic sclerosis (SSc) in a large French Caucasian population...
  72. ncbi request reprint Systemic sclerosis and gastric MALT lymphoma
    Laurent Arnaud
    Service de Rhumatologie A, Hopital Cochin, AP HP, Universite Paris V, France
    Joint Bone Spine 73:105-8. 2006
    ..Moderate mucosal infiltration by endoscopic ultrasonography was the only finding from staging investigations. Six months after treatment to eradicate H. pylori, a repeat endoscopy showed no evidence of the lesion...
  73. ncbi request reprint Lack of specificity of the 6-minute walk test as an outcome measure for patients with systemic sclerosis
    Yoland Schoindre
    Universite Paris Descartes, Service de Rhumatologie A, Departement de Cardiologie, and Service Physiologie et Explorations Fonctionnelles, Hopital Cochin, AP HP, 75014 Paris, France
    J Rheumatol 36:1481-5. 2009
    ..However, conflicting results have been reported in systemic sclerosis (SSc). Our objective was to evaluate the relationships of the 6-min walking distance (6MWD) and organ damage in SSc...
  74. ncbi request reprint Association study of serotonin transporter gene (SLC6A4) in systemic sclerosis in European Caucasian populations
    Julien Wipff
    Service de Rhumatologie A, Hopital Cochin, 27 rue du Faubourg St Jacques, 75014 Paris, France
    J Rheumatol 37:1164-7. 2010
    ..Our objective was to determine whether polymorphisms of SLC6A4 confer susceptibility to SSc and its vascular phenotype...
  75. doi request reprint Systemic sclerosis and cardiac dysfunction: evolving concepts and diagnostic methodologies
    Yannick Allanore
    Departments of Rheumatology A, France bCardiology, Paris Descartes University, Cochin Hospital, AP HP, Paris, France
    Curr Opin Rheumatol 20:697-702. 2008
    ..Clinically evident cardiac involvement is recognized to be a poor prognostic factor; thus preclinical identification is highly encouraged...
  76. ncbi request reprint Systemic sclerosis: an update in 2008
    Yannick Allanore
    Paris Descartes University, Medical Faculty, Department of Rheumatology A, Cochin Hospital, AP HP and INSERM U781, Necker Hospital, Paris, France
    Joint Bone Spine 75:650-5. 2008
    ..This article deals with current and possible future therapeutic options...
  77. ncbi request reprint Evaluation of depression and anxiety in patients with systemic sclerosis
    Cécile Legendre
    Rheumatology Department A, Cochin Teaching Hospital, Paris V University, AP HP, 27 rue du Faubourg St Jacques, 75014 Paris, France
    Joint Bone Spine 72:408-11. 2005
    ..To determine the prevalence of depression and anxiety in patients receiving follow-up in France for systemic sclerosis...
  78. ncbi request reprint Arterial stiffness predicts severe progression in systemic sclerosis: the ERAMS study
    Joel Constans
    Vascular and Internal Medicine Unit, CHU Bordeaux, Paris, France
    J Hypertens 25:1900-6. 2007
    ..The ERAMS study addressed the value of arterial stiffness in predicting the severity of systemic sclerosis...
  79. ncbi request reprint Polymorphic markers of the fibrillin-1 gene and systemic sclerosis in European Caucasian patients
    Julien Wipff
    Department of Rheumatology A, Paris Descartes University, Medical Faculty, Cochin Hospital, AP HP, Paris, France
    J Rheumatol 35:643-9. 2008
    ..Significant associations have been found with the fibrillin-1 gene (FBN1) in Choctaw and Japanese populations. We investigated FBN1 polymorphisms in cohorts of European Caucasian patients...
  80. ncbi request reprint Myocardial dysfunction in rheumatoid arthritis: a controlled tissue-Doppler echocardiography study
    Christophe Meune
    Department of Cardiology, Paris Descartes University, Medical School, Cochin Hospital, Paris, France
    J Rheumatol 34:2005-9. 2007
    ..To determine the sensitivity and accuracy of tissue-Doppler echocardiography (TDE) to assess myocardial contractility. Heart failure is one of the determinants of the excess in mortality in patients with rheumatoid arthritis (RA)...
  81. ncbi request reprint Treatment of systemic sclerosis
    Yannick Allanore
    Rheumatology A Department, Cochin Teaching Hospital, Assistance Publique Hopitaux de Paris, Paris 5 University, 27, rue du Faubourg Saint Jacques, 75014 Paris, France
    Joint Bone Spine 73:363-8. 2006
    ..Available results indicate that emphasis should be put on cardiovascular drugs. The development of criteria for disease activity and severity would facilitate future research on the treatment of systemic sclerosis...
  82. ncbi request reprint Osteoarticular involvement in a series of 100 patients with sarcoidosis referred to rheumatology departments
    Natacha Thelier
    Department of Rheumatology A, Paris Descartes University, Paris, France
    J Rheumatol 35:1622-8. 2008
    ..To analyze the pattern of osteoarticular lesions in patients with sarcoidosis hospitalized in 4 rheumatology departments...
  83. ncbi request reprint Genetic basis for systemic sclerosis
    Yannick Allanore
    Paris Descartes University, School of Medicine, Rheumatology A Department, Cochin Teaching Hospital, AP HP, Paris, France
    Joint Bone Spine 74:577-83. 2007
    ..Investigations into the genetics of systemic sclerosis may shed light on the complex pathophysiology of this disease, help to identify factors that predict organ involvement, and suggest new treatment strategies...
  84. doi request reprint Association of metalloproteinase gene polymorphisms with systemic sclerosis in the European Caucasian population
    Julien Wipff
    Universite Paris Descartes, AP HP, Hopital Cochin, France
    J Rheumatol 37:599-602. 2010
    ..Our aim was to determine whether polymorphisms of the MMP2, MMP9, and MMP14 genes confer susceptibility to SSc in a large population...
  85. ncbi request reprint High redox thioredoxin but low thioredoxin reductase activities in the serum of patients with rheumatoid arthritis
    Herve Lemarechal
    Department of Biochemistry A, Paris 5 University, Assistance Publique Hopitaux de Paris, Cochin Hospital, Paris, France
    Clin Chim Acta 367:156-61. 2006
    ..Thioredoxin (Trx)/thioredoxin reductase (TrxR) is a redox-active system induced by oxidative stress. We investigated its status as a function of RA disease activity...
  86. doi request reprint Usefulness of routine electrocardiography for heart disease screening in patients with spondyloarthropathy or rheumatoid arthritis
    Tiphaine Miquel Goulenok
    Services de Rhumatologie A, Hopital Cochin, AP HP, Universite Paris Descartes, 27, rue du faubourg 75679 Paris cedex 14, France
    Joint Bone Spine 77:146-50. 2010
    ..To assess the usefulness of routine electrocardiography for heart disease screening in patients with spondyloarthropathy (SpA) or rheumatoid arthritis (RA)...
  87. ncbi request reprint New therapeutic strategies in the management of systemic sclerosis
    Yannick Allanore
    Rene Descartes University, Medical Faculty, Department of Rheumatology A, Cochin Hospital, Paris, France
    Expert Opin Pharmacother 8:607-15. 2007
    ..However, recent epidemiological data have revealed a decrease in excess mortality, which may be mostly due to the use of cardiovascular drugs. This article deals with present and possible future therapeutic options...
  88. ncbi request reprint Association between rheumatoid arthritis and primary biliary cirrhosis
    Caroline Caramella
    Service de Rhumatologie A, Universite Rene Descartes, Faculte de Medecine, Hopital Cochin, Assistance Publique Hopitaux de Paris, 75014 Paris, France
    Joint Bone Spine 74:279-81. 2007
    ..We report two cases of such an association. Both of these patients presented severe erosive RA. We discuss the therapeutic management of these patients, taking into account hepatic involvement and drug toxicity...
  89. doi request reprint Safety and efficacy of rituximab in systemic lupus erythematosus: results from 136 patients from the French AutoImmunity and Rituximab registry
    Benjamin Terrier
    Bicetre Hospital, Assistance Publique Hopitaux de Paris, and Paris 11 University, Le Kremlin Bicetre, France
    Arthritis Rheum 62:2458-66. 2010
    ..However, in 2 recent randomized controlled trials (RCTs) of RTX, the primary end points were not met. We undertook this study to evaluate the safety and efficacy of RTX in off-trial patients with SLE seen in regular clinical practice...
  90. doi request reprint Characteristics of joint involvement and relationships with systemic inflammation in systemic sclerosis: results from the EULAR Scleroderma Trial and Research Group (EUSTAR) database
    Jerome Avouac
    Service de Rhumatologie A, Hopital Cochin, Universite Paris Descartes, 75014 Paris, France
    J Rheumatol 37:1488-501. 2010
    ..To determine the prevalence of and independent factors associated with joint involvement in a large population of patients with systemic sclerosis (SSc)...
  91. doi request reprint Genetic background of systemic sclerosis: autoimmune genes take centre stage
    Yannick Allanore
    Universite Paris Descartes, Service de Rhumatologie A, Hopital Cochin, 27 rue du Faubourg St Jacques, 75014 Paris, France
    Rheumatology (Oxford) 49:203-10. 2010
    ..Most likely, these immune-modifying genes could interact and influence both disease phenotype and severity. Less evidence is available yet with regard to genetic markers relating to the vascular and fibrotic aspects of the disease...
  92. doi request reprint Anti-RNA polymerase III antibody prevalence and associated clinical manifestations in a large series of French patients with systemic sclerosis: a cross-sectional study
    Olivier Meyer
    Universite Paris 7 Denis Diderot, UFR de Medecine, APHP Hôpital Bichat, Service de Rhumatologie, Paris, France
    J Rheumatol 37:125-30. 2010
    ..To determine the prevalence of anti-RNA polymerase III autoantibodies in French patients with systemic sclerosis (SSc) and to identify the associated clinical manifestations...
  93. doi request reprint Endothelial progenitor cells and rheumatic disorders
    Jerome Avouac
    Rheumatology A Department, Rene Descartes University, Cochin Hospital, APHP, 27 rue du Faubourg Saint Jacques, 75014 Paris, France
    Joint Bone Spine 75:131-7. 2008
    ..EPCs are important in vasculogenesis, and may be involved in other systemic features of inflammatory rheumatic disorders...
  94. doi request reprint TNF receptor-associated periodic syndrome (TRAPS): a new cause of joint destruction?
    Yoland Schoindre
    Service de Rhumatologie A, Hopital Cochin, AP HP, Universite Paris Descartes, 75014 Paris, France
    Joint Bone Spine 76:567-9. 2009
    ..To our knowledge, this is the first reported case of joint destruction related to TRAPS. In patients with refractory inflammatory joint disease, the presence of extraarticular manifestations, however mundane, should suggest TRAPS...
  95. ncbi request reprint Osteosarcoma presenting as a solitary focus of osteolysis in the calvarium
    Caroline Caramella
    Rhumatology A Department, Paris V University, Cochin Teaching Hospital, APHP, 27, rue du Faubourg Saint Jacques, 75014 Paris, France
    Joint Bone Spine 73:459-61. 2006
    ..However, the heterogeneous and aggressive appearance of the skull lesion prompted a surgical biopsy, which showed osteoblastic osteosarcoma. Chemotherapy and radiation therapy were given after complete excision of the tumor...
  96. doi request reprint Trends in cardiovascular mortality in patients with rheumatoid arthritis over 50 years: a systematic review and meta-analysis of cohort studies
    Christophe Meune
    Department of Cardiology, Cochin Hospital, 27 rue du Fg St Jacques, 75014 Paris, France
    Rheumatology (Oxford) 48:1309-13. 2009
    ..Thus, we set out to estimate the magnitude of the overall increase in CV mortality associated with RA and to determine whether it has decreased over the past 50 years...
  97. ncbi request reprint Autoantibody induction in patients with refractory spondyloarthropathy treated with infliximab and methotrexate
    Jeremie Sellam
    Rheumatology Department A, Paris V University, Cochin Teaching Hospital, AP HP, 27, rue du Faubourg Saint Jacques, 75014 Paris, France
    Joint Bone Spine 72:48-52. 2005
    ..We investigated antibody induction in patients with spondyloarthropathy treated with both infliximab and methotrexate...
  98. ncbi request reprint Rituximab therapy in rheumatoid arthritis in daily practice
    Noémie Assous
    Department of Rheumatology A and Rheumatology B, Paris Descartes University, Medical Faculty, Cochin Hospital, AP HP, Paris, France
    J Rheumatol 35:31-4. 2008
    ..Our aim was to assess in routine care the effects of rituximab in patients with RA who had experienced an inadequate response to anti-tumor necrosis factor-alpha (TNF-alpha) agents or had a contraindication to these drugs...
  99. ncbi request reprint Early detection of pulmonary arterial hypertension in systemic sclerosis: a French nationwide prospective multicenter study
    Eric Hachulla
    Hopital Claude Huriez, Lille, France
    Arthritis Rheum 52:3792-800. 2005
    ....
  100. ncbi request reprint Cardiovascular mortality in patients with inflammatory rheumatic disorders
    Yannick Allanore
    Joint Bone Spine 74:120-2. 2007
  101. ncbi request reprint Anti-endothelial cell antibodies from patients with limited cutaneous systemic sclerosis bind to centromeric protein B (CENP-B)
    Amélie Servettaz
    Universite Paris Descartes, Faculte de Medecine, UPRES EA 1833, Laboratoire d Immunologie, Paris, France
    Clin Immunol 120:212-9. 2006
    ..The main target of anti-endothelial cell antibodies in patients with limited cutaneous SSc is the nuclear and ubiquitous protein CENP-B...