Avelin F Aghokeng

Summary

Country: France

Publications

  1. pmc Virological outcome and patterns of HIV-1 drug resistance in patients with 36 months' antiretroviral therapy experience in Cameroon
    Avelin F Aghokeng
    Virology Laboratory CREMER IMPM IRD, Yaounde, Cameroon
    J Int AIDS Soc 16:18004. 2013
  2. doi request reprint Scale-up of antiretroviral treatment in sub-Saharan Africa is accompanied by increasing HIV-1 drug resistance mutations in drug-naive patients
    Avelin F Aghokeng
    Virology Laboratory CREMER IMPM IRD, Yaounde, Cameroon
    AIDS 25:2183-8. 2011
  3. pmc High failure rate of the ViroSeq HIV-1 genotyping system for drug resistance testing in Cameroon, a country with broad HIV-1 genetic diversity
    Avelin F Aghokeng
    Virology Laboratory CREMER IMPM IRD, Rue Elig Essono, P O Box 1857, Yaounde, Cameroon
    J Clin Microbiol 49:1635-41. 2011
  4. pmc Declining trends in early warning indicators for HIV drug resistance in Cameroon from 2008-2010: lessons and challenges for low-resource settings
    Joseph Fokam
    Chantal BIYA International Reference Centre CIRCB for research on HIV AIDS prevention and management, Yaounde, Cameroon
    BMC Public Health 13:308. 2013
  5. pmc Inaccurate diagnosis of HIV-1 group M and O is a key challenge for ongoing universal access to antiretroviral treatment and HIV prevention in Cameroon
    Avelin F Aghokeng
    Virology Laboratory IMPM IRD, Yaounde, Cameroon
    PLoS ONE 4:e7702. 2009
  6. pmc Population-based monitoring of emerging HIV-1 drug resistance on antiretroviral therapy and associated factors in a sentinel site in Cameroon: low levels of resistance but poor programmatic performance
    Serge C Billong
    National HIV Drug Resistance Prevention and Surveillance Working Group, Yaounde, Cameroon
    PLoS ONE 8:e72680. 2013
  7. doi request reprint WHO clinical criteria-based initiation of antiretroviral therapy: lessons from rural district hospitals in Cameroon with regard to 2009 revised WHO recommendations
    Charles Kouanfack
    Central Hospital, Yaounde, Cameroon
    Trop Med Int Health 15:580-3. 2010
  8. doi request reprint Failure to detect simian immunodeficiency virus infection in a large Cameroonian cohort with high non-human primate exposure
    Cyrille F Djoko
    Global Viral Forecasting, Yaounde, Cameroon
    Ecohealth 9:17-23. 2012
  9. doi request reprint Lamivudine-resistant HBV infection in HIV-positive patients receiving antiretroviral therapy in a public routine clinic in Cameroon
    Charles Kouanfack
    Central Hospital, UMI 233, Yaounde, Cameroon
    Antivir Ther 17:321-6. 2012
  10. pmc Genetic diversity of simian lentivirus in wild De Brazza's monkeys (Cercopithecus neglectus) in Equatorial Africa
    Avelin F Aghokeng
    Laboratoire Retrovirus, IRD UMR 145 VIH et Maladies Associées and the Department of International Health, University of Montpellier I, Montpellier, France
    J Gen Virol 91:1810-6. 2010

Collaborators

Detail Information

Publications17

  1. pmc Virological outcome and patterns of HIV-1 drug resistance in patients with 36 months' antiretroviral therapy experience in Cameroon
    Avelin F Aghokeng
    Virology Laboratory CREMER IMPM IRD, Yaounde, Cameroon
    J Int AIDS Soc 16:18004. 2013
    ..We assessed the virological outcome and drug resistance mutations in patients with 36 months' ART experience, and monitored according to the WHO public health approach in Cameroon...
  2. doi request reprint Scale-up of antiretroviral treatment in sub-Saharan Africa is accompanied by increasing HIV-1 drug resistance mutations in drug-naive patients
    Avelin F Aghokeng
    Virology Laboratory CREMER IMPM IRD, Yaounde, Cameroon
    AIDS 25:2183-8. 2011
    ..To evaluate the frequency and progression over time of the WHO-defined transmitted HIV-1 drug resistance mutations (DRMs) among antiretroviral treatment (ART)-naive HIV-1-infected patients in Cameroon...
  3. pmc High failure rate of the ViroSeq HIV-1 genotyping system for drug resistance testing in Cameroon, a country with broad HIV-1 genetic diversity
    Avelin F Aghokeng
    Virology Laboratory CREMER IMPM IRD, Rue Elig Essono, P O Box 1857, Yaounde, Cameroon
    J Clin Microbiol 49:1635-41. 2011
    ..In this study, we used a panel of diverse HIV-1 group M isolates circulating in Cameroon to show that the performance of this assay can be altered by the sequence variation of non-B HIV-1 strains that predominate in African settings...
  4. pmc Declining trends in early warning indicators for HIV drug resistance in Cameroon from 2008-2010: lessons and challenges for low-resource settings
    Joseph Fokam
    Chantal BIYA International Reference Centre CIRCB for research on HIV AIDS prevention and management, Yaounde, Cameroon
    BMC Public Health 13:308. 2013
    ....
  5. pmc Inaccurate diagnosis of HIV-1 group M and O is a key challenge for ongoing universal access to antiretroviral treatment and HIV prevention in Cameroon
    Avelin F Aghokeng
    Virology Laboratory IMPM IRD, Yaounde, Cameroon
    PLoS ONE 4:e7702. 2009
    ..We here evaluated currently used HIV diagnostic tests and algorithms in Cameroon for their ability to correctly identify HIV infections...
  6. pmc Population-based monitoring of emerging HIV-1 drug resistance on antiretroviral therapy and associated factors in a sentinel site in Cameroon: low levels of resistance but poor programmatic performance
    Serge C Billong
    National HIV Drug Resistance Prevention and Surveillance Working Group, Yaounde, Cameroon
    PLoS ONE 8:e72680. 2013
    ..However, challenges in long-term ART, adherence and HIV drug resistance (HIVDR) itself, require monitoring to limit HIVDR emergence among ART-experienced populations, in order to ensure regimen efficacy...
  7. doi request reprint WHO clinical criteria-based initiation of antiretroviral therapy: lessons from rural district hospitals in Cameroon with regard to 2009 revised WHO recommendations
    Charles Kouanfack
    Central Hospital, Yaounde, Cameroon
    Trop Med Int Health 15:580-3. 2010
    ....
  8. doi request reprint Failure to detect simian immunodeficiency virus infection in a large Cameroonian cohort with high non-human primate exposure
    Cyrille F Djoko
    Global Viral Forecasting, Yaounde, Cameroon
    Ecohealth 9:17-23. 2012
    ....
  9. doi request reprint Lamivudine-resistant HBV infection in HIV-positive patients receiving antiretroviral therapy in a public routine clinic in Cameroon
    Charles Kouanfack
    Central Hospital, UMI 233, Yaounde, Cameroon
    Antivir Ther 17:321-6. 2012
    ..We assessed the HBV prevalence and the rate and pattern of lamivudine-resistant HBV mutations in Cameroonian HIV-infected, ART-treated patients...
  10. pmc Genetic diversity of simian lentivirus in wild De Brazza's monkeys (Cercopithecus neglectus) in Equatorial Africa
    Avelin F Aghokeng
    Laboratoire Retrovirus, IRD UMR 145 VIH et Maladies Associées and the Department of International Health, University of Montpellier I, Montpellier, France
    J Gen Virol 91:1810-6. 2010
    ..These observations suggest a longstanding virus-host co-evolution. SIVdeb prevalence is high in wild De Brazza's populations and thus represents a current risk for humans exposed to these primates in central Africa...
  11. pmc Full-length sequence analysis of SIVmus in wild populations of mustached monkeys (Cercopithecus cephus) from Cameroon provides evidence for two co-circulating SIVmus lineages
    Avelin F Aghokeng
    Laboratoire Retrovirus, UMR 145, IRD and the Department of International Health, University of Montpellier I, Montpellier, France
    Virology 360:407-18. 2007
    ..These results indicate that cross-species transmission and recombination play a major role in the evolution of primate lentiviruses among sympatric primate species...
  12. ncbi request reprint Widely varying SIV prevalence rates in naturally infected primate species from Cameroon
    Avelin F Aghokeng
    Laboratoire Retrovirus, UMR145, IRD, Institute for Research and Development, Montpellier, France
    Virology 345:174-89. 2006
    ..The newly developed assays should now permit to define with greater accuracy existing SIV reservoirs and associated human zoonotic risk...
  13. pmc Characterization of a new simian immunodeficiency virus strain in a naturally infected Pan troglodytes troglodytes chimpanzee with AIDS related symptoms
    Lucie Etienne
    UMR145, Institut de Recherche pour le Développement IRD and Université Montpellier 1, Montpellier, France
    Retrovirology 8:4. 2011
    ..Here, we report a case of naturally-acquired SIVcpz infection in a P.t.troglodytes chimpanzee with clinical and biological data and analysis of viral evolution over the course of infection...
  14. doi request reprint Extraordinary heterogeneity of virological outcomes in patients receiving highly antiretroviral therapy and monitored with the world health organization public health approach in sub-saharan Africa and southeast Asia
    Avelin F Aghokeng
    Virology Laboratory, CREMER IMPM IRD, Yaounde, Cameroon
    Clin Infect Dis 58:99-109. 2014
    ..Our findings show heterogeneous virological failure and illustrate that, in addition to routine access to viral load, good management of ART programs is even more critical to improve treatment outcomes in resource-limited countries. ..
  15. ncbi request reprint Evaluation of transmitted HIV drug resistance among recently-infected antenatal clinic attendees in four Central African countries
    Avelin F Aghokeng
    Virology Laboratory CRESAR IMPM Institut de Recherche pour le Développement, Yaounde, Cameroon
    Antivir Ther 14:401-11. 2009
    ..We evaluated the extent of transmission of drug-resistant HIV strains in four Central African countries: the Republic of Congo, Central African Republic, Chad and Cameroon...
  16. ncbi request reprint Drug resistance mutations of HIV type 1 non-B viruses to integrase inhibitors in treatment-naive patients from sub-saharan countries and discordant interpretations
    Marjorie Monleau
    UMI TransVIHMI, Institut de Recherche pour le Developpement, Montpellier, France
    AIDS Res Hum Retroviruses 28:1157-60. 2012
    ..These results illustrated the need of further in vitro and clinical studies involving non-B viruses to better understand the real significance of observed mutations and harmonize interpretations...
  17. pmc Early warning indicators for HIV drug resistance in Cameroon during the year 2010
    Serge C Billong
    National HIV Drug Resistance Surveillance and Prevention Working Group, HIVDR WG, National AIDS Control Committee, Yaounde, Cameroon
    PLoS ONE 7:e36777. 2012
    ..In order to sustain the effectiveness of ART in a resource-limited country like Cameroon, HIVDR early warning indicators (EWI) may provide relevant corrective measures to support the control and therapeutic management of AIDS...