A Abdelkefi

Summary

Country: France

Publications

  1. ncbi Bone marrow transplantation for patients with acquired severe aplastic anemia using cyclophosphamide and antithymocyte globulin: the experience from a single center
    Abderrahman Abdelkefi
    Centre National de Greffe de Moelle Osseuse CNGMO, Rue Jebel Lakhdar, 1006 Bab Saadoun, Tunis, Tunisia
    Hematol J 4:208-13. 2003
  2. ncbi Detection of catheter-related bloodstream infections by the Gram stain-acridine orange leukocyte cytospin test in hematopoietic stem cell transplant recipients
    A Abdelkefi
    Centre National de Greffe de Moelle Osseuse, Tunis, Tunisia
    Bone Marrow Transplant 37:595-9. 2006
  3. ncbi Use of heparin-coated central venous lines to prevent catheter-related bloodstream infection
    Abderrahman Abdelkefi
    Centre National de Greffe de Moelle Osseuse, Tu nis, Tunisia
    J Support Oncol 5:273-8. 2007
  4. ncbi Isolated extramedullary relapse in the breast of a patient with acute myeloid leukemia following allogeneic stem cell transplantation: case report and review of the literature
    Abderrahman Abdelkefi
    Centre National de Greffe de Moelle Osseuse, Tunis, Tunisia
    Int J Hematol 85:149-53. 2007
  5. ncbi Single autologous stem-cell transplantation followed by maintenance therapy with thalidomide is superior to double autologous transplantation in multiple myeloma: results of a multicenter randomized clinical trial
    Abderrahman Abdelkefi
    Centre National de Greffe de Moelle Osseuse, Tunis, Tunisia
    Blood 111:1805-10. 2008
  6. ncbi Prospective randomised comparison of the COBE spectra version 6 and haemonetics MCS(+) cell separators for hematopoietic progenitor cells leucapheresis in patients with multiple myeloma
    A Abdelkefi
    Centre National de Greffe de Moelle Osseuse, Tunis, Tunisia
    J Clin Apher 21:111-5. 2006
  7. ncbi Hemophagocytic syndrome after hematopoietic stem cell transplantation: a prospective observational study
    Abderrahman Abdelkefi
    Centre National de Greffe de Moelle Osseuse, Bab Saadoun, Tunis, Tunisia
    Int J Hematol 89:368-73. 2009
  8. ncbi Randomized trial of prevention of catheter-related bloodstream infection by continuous infusion of low-dose unfractionated heparin in patients with hematologic and oncologic disease
    Abderrahman Abdelkefi
    Centre National de Greffe de Moelle Osseuse, Bab Saadoun, Tunis, Tunisie
    J Clin Oncol 23:7864-70. 2005
  9. ncbi Prevalence of inherited prothrombotic abnormalities and central venous catheter-related thrombosis in haematopoietic stem cell transplants recipients
    A Abdelkefi
    Centre National de Greffe de Moelle Osseuse, Tunis, Tunisia
    Bone Marrow Transplant 36:885-9. 2005
  10. ncbi First-line thalidomide-dexamethasone therapy in preparation for autologous stem cell transplantation in young patients (<61 years) with symptomatic multiple myeloma
    A Abdelkefi
    Centre National de Greffe de Moelle Osseuse, Tunis, Tunisia
    Bone Marrow Transplant 36:193-8. 2005

Collaborators

Detail Information

Publications28

  1. ncbi Bone marrow transplantation for patients with acquired severe aplastic anemia using cyclophosphamide and antithymocyte globulin: the experience from a single center
    Abderrahman Abdelkefi
    Centre National de Greffe de Moelle Osseuse CNGMO, Rue Jebel Lakhdar, 1006 Bab Saadoun, Tunis, Tunisia
    Hematol J 4:208-13. 2003
    ..This study confirms the high success rate of the CY/ATG regimen in SAA allografted from an HLA-identical sibling. Early and late graft failure remains a problem and may require modification of this regimen...
  2. ncbi Detection of catheter-related bloodstream infections by the Gram stain-acridine orange leukocyte cytospin test in hematopoietic stem cell transplant recipients
    A Abdelkefi
    Centre National de Greffe de Moelle Osseuse, Tunis, Tunisia
    Bone Marrow Transplant 37:595-9. 2006
    ..The Gram stain-AOLC was positive in only two patients (7.6%) with a CRBI. Our results suggest that the Gram stain-AOLC test is not useful for the diagnosis of catheter-related bloodstream infection in HSCT recipients.2006...
  3. ncbi Use of heparin-coated central venous lines to prevent catheter-related bloodstream infection
    Abderrahman Abdelkefi
    Centre National de Greffe de Moelle Osseuse, Tu nis, Tunisia
    J Support Oncol 5:273-8. 2007
    ..00). We did not observe heparin-induced thrombocytopenia. The use of heparin-coated catheters can be a safe and effective approach to the prevention of catheter-related bloodstream infection in patients with hematooncologic disease...
  4. ncbi Isolated extramedullary relapse in the breast of a patient with acute myeloid leukemia following allogeneic stem cell transplantation: case report and review of the literature
    Abderrahman Abdelkefi
    Centre National de Greffe de Moelle Osseuse, Tunis, Tunisia
    Int J Hematol 85:149-53. 2007
    ..Combined treatment with radiation and high-dose chemotherapy may be effective...
  5. ncbi Single autologous stem-cell transplantation followed by maintenance therapy with thalidomide is superior to double autologous transplantation in multiple myeloma: results of a multicenter randomized clinical trial
    Abderrahman Abdelkefi
    Centre National de Greffe de Moelle Osseuse, Tunis, Tunisia
    Blood 111:1805-10. 2008
    ..This study was registered at www.ClinicalTrials.gov as (NCT 00207805)...
  6. ncbi Prospective randomised comparison of the COBE spectra version 6 and haemonetics MCS(+) cell separators for hematopoietic progenitor cells leucapheresis in patients with multiple myeloma
    A Abdelkefi
    Centre National de Greffe de Moelle Osseuse, Tunis, Tunisia
    J Clin Apher 21:111-5. 2006
    ..In conclusion, our study shows that COBE Spectra Version 6 is faster and has a better yield than the Haemonetics MCS(+), in patients with multiple myeloma...
  7. ncbi Hemophagocytic syndrome after hematopoietic stem cell transplantation: a prospective observational study
    Abderrahman Abdelkefi
    Centre National de Greffe de Moelle Osseuse, Bab Saadoun, Tunis, Tunisia
    Int J Hematol 89:368-73. 2009
    ..The rapid diagnosis of HPS and the early initiation of an appropriate treatment are essential for patient management...
  8. ncbi Randomized trial of prevention of catheter-related bloodstream infection by continuous infusion of low-dose unfractionated heparin in patients with hematologic and oncologic disease
    Abderrahman Abdelkefi
    Centre National de Greffe de Moelle Osseuse, Bab Saadoun, Tunis, Tunisie
    J Clin Oncol 23:7864-70. 2005
    ..The purpose of this study was to evaluate the role of low-dose unfractionated heparin in preventing catheter-related bloodstream infection in patients with hemato-oncological disease...
  9. ncbi Prevalence of inherited prothrombotic abnormalities and central venous catheter-related thrombosis in haematopoietic stem cell transplants recipients
    A Abdelkefi
    Centre National de Greffe de Moelle Osseuse, Tunis, Tunisia
    Bone Marrow Transplant 36:885-9. 2005
    ..In view of physicians' reluctance to prescribe prophylactic anticoagulant treatment in these patients, a priori determination of inherited prothrombotic abnormalities may form a basis to guide these treatment decisions...
  10. ncbi First-line thalidomide-dexamethasone therapy in preparation for autologous stem cell transplantation in young patients (<61 years) with symptomatic multiple myeloma
    A Abdelkefi
    Centre National de Greffe de Moelle Osseuse, Tunis, Tunisia
    Bone Marrow Transplant 36:193-8. 2005
    ..First-line thalidomide-dexamethasone therapy is effective and relatively well tolerated in young patients with symptomatic multiple myeloma. This combination does not affect PBSC mobilisation...
  11. ncbi Difference in time to positivity is useful for the diagnosis of catheter-related bloodstream infection in hematopoietic stem cell transplant recipients
    A Abdelkefi
    Centre National de Greffe de Moelle Osseuse, Tunis, Tunisia
    Bone Marrow Transplant 35:397-401. 2005
    ..In conclusion, differential time to positivity of 120 min or more is sensitive and specific for catheter-related bacteremia in hematopoietic stem cell transplant recipients who have nontunnelled short-term catheters...
  12. ncbi Plasmodium falciparum causing hemophagocytic syndrome after allogeneic blood stem cell transplantation
    Abderrahman Abdelkefi
    Centre National de Greffe de Moelle Osseuse, Rue Jebel Lakhdar, Bab Saadoun, 1006 Tunis, Tunisia
    Hematol J 5:449-50. 2004
    ..We report the first case of profound hemophagocytosis in immunosuppressed patient with malaria of high parasitemia after a bone marrow transplant...
  13. ncbi Treatment of a patient with chronic renal failure with rituximab for a follicular lymphoma: safe and successful option of rituximab therapy
    A Abdelkefi
    Centre National de Greffe de Moelle Osseuse, Tunis, Tunisia
    Eur J Haematol 71:128-9. 2003
    ..In January 2003, she received one maintenance course of rituximab. Six weeks after maintenance therapy, a complete response was achieved...
  14. ncbi [Infectious complications related to non-tunneled central venous catheters in immunocompromised patients: prospective study about 210 cases]
    A Abdelkefi
    Centre National de Greffe de Moelle Osseuse, Tunis, Tunisie
    Ann Fr Anesth Reanim 22:773-7. 2003
    ..To evaluate infectious complications related to non-tunneled central venous catheter in immunocompromised patients, in a bone marrow unit...
  15. ncbi Rejection of the second allogeneic graft in a child with Fanconi anemia reversed by antilymphocyte globulin and donor lymphocyte infusion
    Abderrahman Abdelkefi
    Centre National de Greffe de Moelle Osseuse, Tunis, Tunisia
    Hematol J 4:452-3. 2003
    ..Her molecular chimerism is of donor origin. Thus, donor lymphocyte infusion can be considered as a therapy option for rejection after allogeneic bone marrow transplantation for FA...
  16. ncbi Prevention of central venous line-related thrombosis by continuous infusion of low-dose unfractionated heparin, in patients with haemato-oncological disease. A randomized controlled trial
    Abderrahman Abdelkefi
    Centre National de Greffe de Moelle Osseuse, Rue Jebel Lakhdar, 1006 Bab Saadoun, Tunis, Tunisia
    Thromb Haemost 92:654-61. 2004
    ..This is the first prospective, randomized study, which shows that low-dose of unfractionated heparin is safe and effective to prevent catheter-related thrombosis in patients with haemato-oncological disease...
  17. ncbi Effectiveness of fixed 50% nitrous oxide oxygen mixture and EMLA cream for insertion of central venous catheters in children
    Abderrahman Abdelkefi
    Centre National de Greffe de Moelle Osseuse, Department of Pediatrics, Tunis, Tunisia
    Pediatr Blood Cancer 43:777-9. 2004
    ..To assess the safety and the effectiveness of this gas mixture for insertion of central venous catheters, we conducted a prospective observational study...
  18. ncbi Analysis of cytomegalovirus (CMV) viremia using the pp65 antigenemia assay, the amplicor CMV test, and a semi-quantitative polymerase chain reaction test after allogeneic marrow transplantation
    H Ksouri
    Service des Laboratoires, Centre National de Greffe de Moelle Osseuse, Tunis, Tunisia
    Transpl Infect Dis 9:16-21. 2007
    ..PMNLs-based assays are more efficient in monitoring CMV reactivation, but for high-risk patients with GVHD, more sensitive assays (real-time PCR) must be done...
  19. ncbi Allogeneic hematopoietic stem cell transplantation in Tunisia
    T Ben Othman
    Hematology Department, Centre National de Greffe de Moelle Osseuse de Tunis, Tunis, Tunisia
    Bone Marrow Transplant 42:S139-S141. 2008
    ..The overall TRM rate was 17%. Outcome depended on indication. According to our results, allogeneic HSCT is potentially curative for hematological diseases, but it is a toxic approach for malignant disorders...
  20. ncbi [Allogenic hematopoietic stem cell transplantation in acquired aplastic anemia: first experience of the National Center for Bone Marrow Grafting]
    A Abdelkefi
    Centre National de Greffe de Moelle Osseuse, Bab Saadoun, Tunis
    Tunis Med 79:498-502. 2001
    ..Another reason for improved survival is the decrease in the incidence and severity of acute graft-versus-host disease...
  21. ncbi Bone marrow transplantation from matched related donors for patients with Fanconi anemia using low-dose busulfan and cyclophosphamide as conditioning
    L Torjemane
    Centre National de Greffe de Moelle Osseuse de Tunis CNGMO, Tunis, Tunisia
    Pediatr Blood Cancer 46:496-500. 2006
    ..The low-dose BU/CY regimen, in FA patients allografted from an HLA-matched related donor, allowed engraftment with relative low toxicity. Early graft failure (GF) remains a problem and may require modification of this regimen...
  22. ncbi High-dose therapy and autologous stem cell transplantation for Hodgkin's lymphoma in relapse or failure after initial chemotherapy : results of the Centre National de Greffe de Moelle Osseuse de Tunis
    Lamia Torjman
    Centre National de Greffe de Moelle Osseuse, Tunis
    Tunis Med 85:35-8. 2007
    ..In the present study we report the clinical outcome of 27 patients with refractory or relapsed Hodgkin's lymphoma (HL) undergoing autologous peripheral stem-cell transplantation (ASCT)...
  23. ncbi [Prognosis value of the pp65 antigenemia and semi-quantitative PCR in the detection of the CMV reactivation in bone marrow grafted patients]
    H Ksouri
    Service des laboratoires du Centre national de greffe de moelle osseuse, Tunis, Tunisie
    Bull Soc Pathol Exot 99:155-9. 2006
    ..Clinical and biological signs presented by our patients in this cases report, seems to be associated more with the GVHD than with CMV reactivation...
  24. ncbi Effect of once-a-day fractionated total body irradiation on the risk of relapse after non-T-cell-depleted HLA-matched sibling transplantation
    Tarek Ben Othman
    Centre National de Greffe de Moelle Osseuse, Rue Jebel Lakhdar, 1006, Bab Saadoun, Tunis, Tunisia
    Radiat Med 25:407-10. 2007
    ....
  25. ncbi Heparin-like anticoagulant associated with multiple myeloma and neutralized with protamine sulfate
    Lamia Torjemane
    Centre National de Greffe de Moelle Osseuse de Tunis, Tunis, Tunisia
    Blood Coagul Fibrinolysis 18:279-81. 2007
    ..Such coagulopathy appears to be a rare mechanism of bleeding and it is an important entity to consider since it is potentially reversible with protamine sulfate...
  26. ncbi Transmission of type 1 diabetes by bone marrow transplantation: a case report
    Fethi Mellouli
    Service d Immuno Hématologie Pédiatrique, Centre National de Greffe de Moelle Osseuse, Tunis, Tunisia
    Pediatr Transplant 13:119-22. 2009
    ..With the predictive value and significance of T1D-associated autoantibodies, we tried to consolidate the T1D transfer possibility based on our patient characteristics and a literature review...
  27. ncbi Possible transfer of vitiligo by allogeneic bone marrow transplantation: a case report
    Fethi Mellouli
    Service d Immuno Hématologie Pédiatrique, Centre National de Greffe de Moelle Osseuse, Tunis, Tunisia
    Pediatr Transplant 13:1058-61. 2009
    ..We reviewed and searched for some particularities in the reported cases of post-BMT vitiligo...
  28. ncbi Switch from beta-thalassemia major to beta-thalassemia intermedia after secondary graft failure
    Fethi Mellouli
    Service d Immuno Hématologie Pédiatrique, Centre National de Greffe de Moelle Osseuse, Tunis, Tunisia
    Exp Clin Transplant 8:269-71. 2010
    ....