Michele Fornaro

Summary

Publications

  1. pmc Tinnitus psychopharmacology: A comprehensive review of its pathomechanisms and management
    Michele Fornaro
    Department of Neuroscience, Section of Psychiatry, University of Genova, Genova, Italy
    Neuropsychiatr Dis Treat 6:209-18. 2010
  2. pmc A Case of Treatment Resistant Depression and Alcohol Abuse in a Person with Mental Retardation: Response to Aripiprazole and Fluvoxamine Therapy upon Consideration of a Bipolar Diathesis after Repetitive Failure to Respond to Multiple Antidepressant Trial
    Michele Fornaro
    Section of Psychiatry, Department of Neuroscience, University of Genova, 16100 Genova, Italy
    Case Report Med 2010:801514. 2010
  3. pmc Adjunctive agomelatine therapy in the treatment of acute bipolar II depression: a preliminary open label study
    Michele Fornaro
    Department of Formative Sciences, University of Catania, Catania, Italy
    Neuropsychiatr Dis Treat 9:243-51. 2013
  4. pmc Prevalence and diagnostic distribution of medically unexplained painful somatic symptoms across 571 major depressed outpatients
    Michele Fornaro
    Department of Neurosciences, Section of Psychiatry, University of Genova, Genoa, Italy
    Neuropsychiatr Dis Treat 7:217-21. 2011
  5. pmc Increase in IL-6 levels among major depressive disorder patients after a 6-week treatment with duloxetine 60 mg/day: a preliminary observation
    Michele Fornaro
    Department of Neuroscience, Section of Psychiatry, University of Genova, Genoa, Italy
    Neuropsychiatr Dis Treat 7:51-6. 2011
  6. pmc Obsessive-compulsive disorder with bipolar diathesis following isotretinoin therapy remitting upon treatment with olanzapine and fluvoxamine
    Michele Fornaro
    Department of Neuroscience, Section of Psychiatry, University of Genoa, Genoa, Italy
    Neuropsychiatr Dis Treat 6:719-22. 2010
  7. pmc Current nosology of treatment resistant depression: a controversy resistant to revision
    Michele Fornaro
    Department of Neuroscience, Section of Psychiatry, University of Genova, Genoa, Italy
    Clin Pract Epidemiol Ment Health 6:20-4. 2010
  8. ncbi VEGF plasma level variations in duloxetine-treated patients with major depression
    Michele Fornaro
    Department of Neuroscience, Section of Psychiatry, IRCCS AOU San Martino IST, Genoa 16100, Italy Scienze della Formazione, University of Catania, Catania, Italy Electronic address
    J Affect Disord 151:590-5. 2013
  9. ncbi Treatment adherence towards prescribed medications in bipolar-II acute depressed patients: relationship with cyclothymic temperament and "therapeutic sensation seeking" in response towards subjective intolerance to pain
    Michele Fornaro
    Department of Educational Sciences, University of Catania, via Ofelia n 1, ZIP 95125, Catania, Italy Electronic address
    J Affect Disord 151:596-604. 2013
  10. doi Sensation seeking in major depressive patients: relationship to sub-threshold bipolarity and cyclothymic temperament
    Michele Fornaro
    Department of Educational Sciences, University of Catania, Catania, Italy
    J Affect Disord 148:375-83. 2013

Collaborators

Detail Information

Publications40

  1. pmc Tinnitus psychopharmacology: A comprehensive review of its pathomechanisms and management
    Michele Fornaro
    Department of Neuroscience, Section of Psychiatry, University of Genova, Genova, Italy
    Neuropsychiatr Dis Treat 6:209-18. 2010
    ..Psychopharmacologic agents, although not being the first-line treatment for tinnitus, may modulate cochlear neurotransmission, thereby influencing the subjective tinnitus experience...
  2. pmc A Case of Treatment Resistant Depression and Alcohol Abuse in a Person with Mental Retardation: Response to Aripiprazole and Fluvoxamine Therapy upon Consideration of a Bipolar Diathesis after Repetitive Failure to Respond to Multiple Antidepressant Trial
    Michele Fornaro
    Section of Psychiatry, Department of Neuroscience, University of Genova, 16100 Genova, Italy
    Case Report Med 2010:801514. 2010
    ..Although further controlled investigations are needed to assess a putative bipolar diathesis in some cases of MR associated to TRD, prudence is advised in the long-term prescription of antidepressant monotherapies in such conditions...
  3. pmc Adjunctive agomelatine therapy in the treatment of acute bipolar II depression: a preliminary open label study
    Michele Fornaro
    Department of Formative Sciences, University of Catania, Catania, Italy
    Neuropsychiatr Dis Treat 9:243-51. 2013
    ....
  4. pmc Prevalence and diagnostic distribution of medically unexplained painful somatic symptoms across 571 major depressed outpatients
    Michele Fornaro
    Department of Neurosciences, Section of Psychiatry, University of Genova, Genoa, Italy
    Neuropsychiatr Dis Treat 7:217-21. 2011
    ..To assess the prevalence and distribution of medically unexplained painful somatic symptoms (PSSs) versus nonpainful somatic symptoms (NPSSs) in patients diagnosed with major depressive episode (MDE)...
  5. pmc Increase in IL-6 levels among major depressive disorder patients after a 6-week treatment with duloxetine 60 mg/day: a preliminary observation
    Michele Fornaro
    Department of Neuroscience, Section of Psychiatry, University of Genova, Genoa, Italy
    Neuropsychiatr Dis Treat 7:51-6. 2011
    ..Nevertheless, no equivalent observation for the SNRI duloxetine has been made to date...
  6. pmc Obsessive-compulsive disorder with bipolar diathesis following isotretinoin therapy remitting upon treatment with olanzapine and fluvoxamine
    Michele Fornaro
    Department of Neuroscience, Section of Psychiatry, University of Genoa, Genoa, Italy
    Neuropsychiatr Dis Treat 6:719-22. 2010
    ..Although rare, severe adulthood psychiatric complications may occur following isotretinoin treatment, requiring management which is individually tailored to the patient...
  7. pmc Current nosology of treatment resistant depression: a controversy resistant to revision
    Michele Fornaro
    Department of Neuroscience, Section of Psychiatry, University of Genova, Genoa, Italy
    Clin Pract Epidemiol Ment Health 6:20-4. 2010
    ....
  8. ncbi VEGF plasma level variations in duloxetine-treated patients with major depression
    Michele Fornaro
    Department of Neuroscience, Section of Psychiatry, IRCCS AOU San Martino IST, Genoa 16100, Italy Scienze della Formazione, University of Catania, Catania, Italy Electronic address
    J Affect Disord 151:590-5. 2013
    ..The objective of the study was to investigate the VEGF level variations in MDD patients during antidepressant treatment with duloxetine, a relatively new SNRI...
  9. ncbi Treatment adherence towards prescribed medications in bipolar-II acute depressed patients: relationship with cyclothymic temperament and "therapeutic sensation seeking" in response towards subjective intolerance to pain
    Michele Fornaro
    Department of Educational Sciences, University of Catania, via Ofelia n 1, ZIP 95125, Catania, Italy Electronic address
    J Affect Disord 151:596-604. 2013
    ....
  10. doi Sensation seeking in major depressive patients: relationship to sub-threshold bipolarity and cyclothymic temperament
    Michele Fornaro
    Department of Educational Sciences, University of Catania, Catania, Italy
    J Affect Disord 148:375-83. 2013
    ....
  11. doi The argument of antidepressant drugs in the treatment of bipolar depression: mixed evidence or mixed states?
    Michele Fornaro
    University of Catania, Department of Formative Sciences, via Teatro Greco n 78, Catania, ZIP 95124, Italy
    Expert Opin Pharmacother 13:2037-51. 2012
    ..The role of antidepressant drugs in acute and maintenance treatment of bipolar depression is a matter of debate that cannot be decided from the evidence available in the current literature...
  12. doi A case of severe oral self-injurious Tourette's syndrome alleviated by pregabalin
    Michele Fornaro
    Scienze della Formazione, University of Catania, Catania, Italy
    Gen Hosp Psychiatry 34:321.e1-4. 2012
    ..Although rigorous controlled studies are required, based on our case study, pregabalin may be a potential treatment option in some cases of SIB with TS...
  13. doi Electroretinographic assessment in major depressed patients receiving duloxetine: might differences between responders and non-responders indicate a differential biological background?
    Michele Fornaro
    Department of Neurosciences, Ophthalmology and Genetics Section of Psychiatry, University of Genova, Italy
    J Affect Disord 135:154-9. 2011
    ..Nonetheless, current evidences are merely preliminary, essentially considering just older classes of antidepressants, thus requiring confirmation studies even with newer agents as duloxetine...
  14. doi Could the underestimation of bipolarity obstruct the search for novel antidepressant drugs?
    Michele Fornaro
    University of Catania, Scienze della Formazione, via Teatro Greco 78, Catania, ZIP 94125, Italy
    Expert Opin Pharmacother 12:2817-31. 2011
    ..Despite the clinical and social relevance of depression, and the availability of numerous antidepressants and non-pharmacological interventions, response rates remain unsatisfactory and novel therapeutic targets are being explored...
  15. ncbi Medicine and psychiatry in Western culture: among Ancient Greek myths and modern prejudices
    Michele Fornaro
    Dipartimento di Neuroscienze, Oftalmologia e Genetica, Universita di Genova, Italy
    Med Secoli 21:1105-22. 2009
    ..The paper explores many human aspects and feelings toward doctors and their cures, referring to ancient myths, focusing on the perception of mental illness...
  16. pmc Switching from serotonin reuptake inhibitors to agomelatine in patients with refractory obsessive-compulsive disorder: a 3 month follow-up case series
    Michele Fornaro
    University of Genova, Department of Psychiatry, Genoa, Italy
    Ann Gen Psychiatry 10:5. 2011
    ..abstract:..
  17. doi Diagnosis of co-morbid axis-I psychiatric disorders among women with newly diagnosed, untreated endocrine disorders
    Michele Fornaro
    Department of Neuroscience, Section of Psychiatry, University of Genova, Genoa, Italy
    World J Biol Psychiatry 11:991-6. 2010
    ..To determine the prevalence of major depressive disorder (MDD) and other selected axis-I disorders among women with newly diagnosed, untreated endocrine disorders...
  18. pmc Obsessive-compulsive disorder and related disorders: a comprehensive survey
    Michele Fornaro
    Dipartimento di Neuroscienze, Oftalmologia e Genetica DINOG, Sezione di Psichiatria, Universita di Genova, Genova, Italy
    Ann Gen Psychiatry 8:13. 2009
    ..Clinicians should become familiar with the broad spectrum of OCD disorders, since it is a pivotal issue in current clinical psychiatry...
  19. ncbi Catatonia: a narrative review
    Michele Fornaro
    Department of Neurosciences, Section of Psychiatry, University of Genova, Ospedale San Martino, Largo R Benzi n 16, Genoa, Italy
    Cent Nerv Syst Agents Med Chem 11:73-9. 2011
    ..The aim of this narrative review is to provide both clinicians and pharmacologists with a narrative, panoramic review on catatonia and associated clinical pictures, focusing on its general pharmacological management...
  20. doi Lifetime co-morbidity with different subtypes of eating disorders in 148 females with bipolar disorders
    M Fornaro
    Dipartimento di Psichiatria, Universita di Genova, Genova, Italy
    J Affect Disord 121:147-51. 2010
    ..To evaluate the impact of Eating Disorders (EDs) lifetime co-morbidity among female with Bipolar Disorders (BDs) and to compare clinical and cognitive features among EDs subgroups...
  21. pmc Adding 5-hydroxytryptamine receptor type 3 antagonists may reduce drug-induced nausea in poor insight obsessive-compulsive patients taking off-label doses of selective serotonin reuptake inhibitors: a 52-week follow-up case report
    Michele Fornaro
    Department of Psychiatry, University of Genova, Genoa, Italy
    Ann Gen Psychiatry 9:39. 2010
    ..Both mirtazapine and olanzapine also act as 5-hydroxytryptamine receptor type 3 (5-HT3) blockers, making them preferred choices especially in cases of drug-induced nausea...
  22. pmc Medicine and psychiatry in Western culture: Ancient Greek myths and modern prejudices
    Michele Fornaro
    Dipartimento di Psichiatria, Universita di Genova, Genoa, Italy
    Ann Gen Psychiatry 8:21. 2009
    ..This paper explores many human aspects and feelings towards doctors and their cures, referring to ancient myths and focusing on the perception of mental illness...
  23. doi Different measures of impulsivity in patients with anxiety disorders: a case control study
    Alessandra Del Carlo
    Department of Psychiatry, University of Pisa, Italy
    Psychiatry Res 197:231-6. 2012
    ..Further investigations are needed to assess the extent to which impulsivity might or might not be directly related to the anxiety disorder...
  24. ncbi NGF serum levels variations in major depressed patients receiving duloxetine
    Matteo Martino
    Department of Neuroscience, Section of Psychiatry, IRCCS AOU San Martino IST, Genoa, Italy Electronic address
    Psychoneuroendocrinology 38:1824-8. 2013
    ..Objective of the study was to investigate NGF levels variations in MDD patients during antidepressant treatment with duloxetine, a relatively newer SNRI...
  25. doi Discriminative hypomania checklist-32 factors in unipolar and bipolar major depressive patients
    Giulio Perugi
    Department of Psychiatry, University of Pisa, Pisa, Italy
    Psychopathology 45:390-8. 2012
    ..The Hypomania Checklist-32 (HCL-32) has therefore been developed and tested internationally to facilitate BD recognition...
  26. doi Unexplained somatic symptoms during major depression: prevalence and clinical impact in a national sample of Italian psychiatric outpatients
    Giulio Perugi
    Dipartimento di Psichiatria, Universita di Pisa, Institute of Behavioural Sciences G De Lisio, Pisa, Italy
    Psychopathology 44:116-24. 2011
    ..The aim of this study was to explore the prevalence and impact of unexplained somatic symptoms during major depression...
  27. doi β-amyloid 1-42 induces physiological transcriptional regulation of BACE1
    Alessandra Piccini
    Department of Internal Medicine and Medical Specialities, University of Genova, Genova, Italy
    J Neurochem 122:1023-31. 2012
    ..Taken together these data imply that monomeric Aβ 1-42, at non-toxic concentrations and time frames, are able to induce a signaling pathway that leads to transcriptional activation of β-secretase...
  28. ncbi Affective temperaments are associated with specific clusters of symptoms and psychopathology: a cross-sectional study on bipolar disorder inpatients in acute manic, mixed, or depressive relapse
    Felice Iasevoli
    Department of Neuroscience, Reproductive Sciences and Odontostomatology University Federico II of Naples, Italy Electronic address
    J Affect Disord 151:540-50. 2013
    ....
  29. doi Might different cytokine trends in depressed patients receiving duloxetine indicate differential biological backgrounds
    Michele Fornaro
    Department of Formative Sciences, University of Catania, via Teatro Greco n 84, ZIP 95125, Catania, Italy
    J Affect Disord 145:300-7. 2013
    ..Objective of the study was to investigate cytokines modulation by duloxetine, a relatively newer SNRI with "clean" dual serotonin/norepinephrine mechanism...
  30. doi Impulsivity in anxiety disorder patients: is it related to comorbid cyclothymia?
    Giulio Perugi
    Department of Psychiatry, University of Pisa, Pisa, Italy
    J Affect Disord 133:600-6. 2011
    ..healthy controls. In the same sample we now explore the influence of comorbid soft bipolar spectrum disorders on the relationship between anxiety disorders and impulsivity...
  31. pmc An open pilot study of zonisamide augmentation in major depressive patients not responding to a low dose trial with duloxetine: preliminary results on tolerability and clinical effects
    Michele Fornaro
    Department of Neuroscience, Section of Psychiatry, University of Genova, Genoa, Italy
    Ann Gen Psychiatry 10:23. 2011
    ..abstract:..
  32. doi Successful use of agomelatine in the treatment of major depression in a woman taking tamoxifen: a case report
    Domenico De Berardis
    National Health Service, Department of Mental Health, Psychiatric Service of Diagnosis and Treatment, Hospital G Mazzini, Teramo Department of Neuroscience and Imaging, University G D Annunzio, Chieti National Health Service, U O S D Senology, Hospital G Mazzini, Teramo Hermanas Hospitalarias, FoRiPsi, Villa S Giuseppe Hospital, Ascoli Piceno Department of Scienze della Formazione, University of Catania, Catania and Department of Health Science, University of L Aquila, L Aquila, Italy
    Clin Neuropharmacol 37:31-3. 2014
    ..We herein report a case of a patient with major depression and concurrent tamoxifen therapy successfully treated with agomelatine monotherapy. ..
  33. doi Application of two different hemostatic procedures during microsurgical median nerve reconstruction in the rat does not hinder axonal regeneration
    Nektarios Sinis
    Department of Plastic Surgery, Martin Luther Hospital, Berlin, Germany
    Neurosurgery 68:1399-403; discussion 1403-4. 2011
    ..It is speculated, however, that extensive hemostasis could provoke significant nerve damage...
  34. pmc Immunomodulation Mechanism of Antidepressants: Interactions between Serotonin/Norepinephrine Balance and Th1/Th2 Balance
    Matteo Martino
    Department of Neuroscience, Section of Psychiatry, University of Genova, Genoa, Italy
    Curr Neuropharmacol 10:97-123. 2012
    ..Furthermore limited data, reviewed here, have shown the effectiveness of some antidepressants as pure immunomodulators. However, these considerations are tentative and require experimental confirmation or refutation by future studies...
  35. doi Epileptic seizures but not pseudoseizures are associated with decreased density of the serotonin transporter in blood platelet membranes
    Aroldo Cupello
    IBFM, CNR, Sezione di Genova, Via De Toni 5, 16132, Genova, Italy
    Neurochem Res 33:2263-8. 2008
    ..These data lend further support to the idea that down regulation of serotonin transporter may play a homeostatic role in the cessation of epileptic seizures...
  36. doi A case of deep venous thrombosis following protracted catatonic immobility recovered with electroconvulsive therapy: the relevance for an early intervention
    Pierpaolo Medda
    Department of Psychiatry, Neurobiology, Pharmacology and Biotechnologies, University of Pisa, Italy
    Gen Hosp Psychiatry 34:209.e5-7. 2012
    ....
  37. pmc A systematic, updated review on the antidepressant agomelatine focusing on its melatonergic modulation
    Michele Fornaro
    Department of Psychiatry, University of Genova, Genoa, Italy
    Curr Neuropharmacol 8:287-304. 2010
    ..To present an updated, comprehensive review on clinical and pre-clinical studies on agomelatine...
  38. doi Upregulation of presenilin 1 in brains of sporadic, late-onset Alzheimer's disease
    Roberta Borghi
    Department of Internal Medicine, University of Genova, Genova, Italy
    J Alzheimers Dis 22:771-5. 2010
    ..We found a significant increase in PS1 mRNA, protein levels and γ-secretase activity in AD cases. These findings suggest that upregulation of PS1 leads to Aβ overproduction and accumulation in sporadic AD...
  39. doi Amyloid-beta42 plasma levels are elevated in amnestic mild cognitive impairment
    Sergio Cammarata
    Department of Neurology, Galliera Hospital, Genova, Italy
    J Alzheimers Dis 18:267-71. 2009
    ..However the large variability of measured values indicates that plasma Abeta is not a suitable marker of incipient AD...