Nathan Ford

Summary

Publications

  1. pmc Review of the safety, efficacy, and pharmacokinetics of elvitegravir with an emphasis on resource-limited settings
    Janice Soo Fern Lee
    Medecins Sans Frontieres, Geneva University Hospital, Geneva, Switzerland
    HIV AIDS (Auckl) 4:5-15. 2012
  2. pmc Preferred antiretroviral drugs for the next decade of scale up
    Isabelle Andrieux-Meyer
    Medecins Sans Frontieres, Geneva, Switzerland
    J Int AIDS Soc 15:17986. 2012
  3. pmc Safety, efficacy, and pharmacokinetics of rilpivirine: systematic review with an emphasis on resource-limited settings
    Nathan Ford
    Medecins Sans Frontieres, Geneva, Switzerland
    HIV AIDS (Auckl) 3:35-44. 2011
  4. pmc Treatment outcomes of treatment-naïve Hepatitis C patients co-infected with HIV: a systematic review and meta-analysis of observational cohorts
    Anna Davies
    Department of Infectious Diseases, Faculty of Medicine, Imperial College, London, United Kingdom
    PLoS ONE 8:e55373. 2013
  5. doi request reprint Adverse events associated with nevirapine use in pregnancy: a systematic review and meta-analysis
    Nathan Ford
    Medecins Sans Frontieres, Geneva, Switzerland
    AIDS 27:1135-43. 2013
  6. pmc Mortality after fluid bolus in children with shock due to sepsis or severe infection: a systematic review and meta-analysis
    Nathan Ford
    Medecins Sans Frontieres, Geneva, Switzerland
    PLoS ONE 7:e43953. 2012
  7. doi request reprint Safety of efavirenz in the first trimester of pregnancy: an updated systematic review and meta-analysis
    Nathan Ford
    Centre for Infectious Disease Epidemiology and Research, University of Cape Town, Cape Town, South Africa
    AIDS 25:2301-4. 2011
  8. pmc Chronic hepatitis C treatment outcomes in low- and middle-income countries: a systematic review and meta-analysis
    Nathan Ford
    Medecins Sans Frontieres, 78 rue de Lausanne, 1211 Geneva, Switzerland
    Bull World Health Organ 90:540-50. 2012
  9. pmc Priorities for developing countries in the global response to non-communicable diseases
    Dermot Maher
    London School of Hygiene and Tropical Medicine, London, England, UK
    Global Health 8:14. 2012
  10. doi request reprint Expanding access to treatment for hepatitis C in resource-limited settings: lessons from HIV/AIDS
    Nathan Ford
    Medecins Sans Frontieres, Geneva, Switzerland
    Clin Infect Dis 54:1465-72. 2012

Collaborators

Detail Information

Publications85

  1. pmc Review of the safety, efficacy, and pharmacokinetics of elvitegravir with an emphasis on resource-limited settings
    Janice Soo Fern Lee
    Medecins Sans Frontieres, Geneva University Hospital, Geneva, Switzerland
    HIV AIDS (Auckl) 4:5-15. 2012
    ..Clinical trials addressing specific challenges encountered in resources-limited settings should be encouraged...
  2. pmc Preferred antiretroviral drugs for the next decade of scale up
    Isabelle Andrieux-Meyer
    Medecins Sans Frontieres, Geneva, Switzerland
    J Int AIDS Soc 15:17986. 2012
    ..This commentary reviews recommendations made in an expert consultation on treatment scale up in resource-limited settings...
  3. pmc Safety, efficacy, and pharmacokinetics of rilpivirine: systematic review with an emphasis on resource-limited settings
    Nathan Ford
    Medecins Sans Frontieres, Geneva, Switzerland
    HIV AIDS (Auckl) 3:35-44. 2011
    ..These characteristics make rilpivirine an attractive drug for resource-limited settings. Future research should assess the potential to improve robustness and assess the clinical significance of interaction with antituberculosis drugs...
  4. pmc Treatment outcomes of treatment-naïve Hepatitis C patients co-infected with HIV: a systematic review and meta-analysis of observational cohorts
    Anna Davies
    Department of Infectious Diseases, Faculty of Medicine, Imperial College, London, United Kingdom
    PLoS ONE 8:e55373. 2013
    ..Co-infection with Hepatitis C (HCV) and HIV is common and HIV accelerates hepatic disease progression due to HCV. However, access to HCV treatment is limited and success rates are generally poor...
  5. doi request reprint Adverse events associated with nevirapine use in pregnancy: a systematic review and meta-analysis
    Nathan Ford
    Medecins Sans Frontieres, Geneva, Switzerland
    AIDS 27:1135-43. 2013
    ..We conducted a systematic review and meta-analysis of severe adverse events in HIV-positive women who initiated NVP while pregnant...
  6. pmc Mortality after fluid bolus in children with shock due to sepsis or severe infection: a systematic review and meta-analysis
    Nathan Ford
    Medecins Sans Frontieres, Geneva, Switzerland
    PLoS ONE 7:e43953. 2012
    ..We conducted a systematic review to assess the evidence base for fluid resuscitation in the treatment of children with shock due to sepsis or severe infection...
  7. doi request reprint Safety of efavirenz in the first trimester of pregnancy: an updated systematic review and meta-analysis
    Nathan Ford
    Centre for Infectious Disease Epidemiology and Research, University of Cape Town, Cape Town, South Africa
    AIDS 25:2301-4. 2011
    ..85 (95% CI 0.61-1.20). One neural tube defect was observed (myelomeningocele), giving an incidence of 0.07% (95% CI 0.002-0.39)...
  8. pmc Chronic hepatitis C treatment outcomes in low- and middle-income countries: a systematic review and meta-analysis
    Nathan Ford
    Medecins Sans Frontieres, 78 rue de Lausanne, 1211 Geneva, Switzerland
    Bull World Health Organ 90:540-50. 2012
    ..To assess the effectiveness of treatment for hepatitis C virus (HCV) infection in low- and middle-income countries and identify factors associated with successful outcomes...
  9. pmc Priorities for developing countries in the global response to non-communicable diseases
    Dermot Maher
    London School of Hygiene and Tropical Medicine, London, England, UK
    Global Health 8:14. 2012
    ....
  10. doi request reprint Expanding access to treatment for hepatitis C in resource-limited settings: lessons from HIV/AIDS
    Nathan Ford
    Medecins Sans Frontieres, Geneva, Switzerland
    Clin Infect Dis 54:1465-72. 2012
    ..Many of these obstacles have been addressed in rolling out treatment for human immunodeficiency virus during the last decade, and a number of lessons can be drawn to help improve access to HCV care...
  11. doi request reprint Safety of task-shifting for male medical circumcision: a systematic review and meta-analysis
    Nathan Ford
    Centre for Infectious Disease Epidemiology and Research, University of Cape Town, Cape Town, South Africa
    AIDS 26:559-66. 2012
    ..We undertook a systematic review and meta-analysis to review the safety of task-shifting for circumcision in Africa...
  12. pmc Male gender predicts mortality in a large cohort of patients receiving antiretroviral therapy in Uganda
    Edward J Mills
    Faculty of Health Sciences, University of Ottawa, Ottawa, Canada
    J Int AIDS Soc 14:52. 2011
    ....
  13. pmc CMV retinitis screening and treatment in a resource-poor setting: three-year experience from a primary care HIV/AIDS programme in Myanmar
    Nini Tun
    California Pacific Medical Center, San Francisco, USA
    J Int AIDS Soc 14:41. 2011
    ..Prior to this programme, CMV retinitis was not routinely examined for, or treated, in Myanmar...
  14. pmc Providing surgical care in Somalia: A model of task shifting
    Kathryn M Chu
    Medecins Sans Frontieres, 49 Jorrisen St, Braamfontein 2017, Johannesburg, South Africa
    Confl Health 5:12. 2011
    ..abstract:..
  15. doi request reprint Early initiation of antiretroviral therapy and associated reduction in mortality, morbidity and defaulting in a nurse-managed, community cohort in Lesotho
    Nathan Ford
    Medecins Sans Frontieres, University of Cape Town, South Africa
    AIDS 24:2645-50. 2010
    ..Lesotho has supported earlier initiation since 2008. We assessed outcomes comparing early (CD4 cell counts >200 cells/μl) and late (CD4 cell counts ≤200 cells/μl) initiation...
  16. pmc The first decade of antiretroviral therapy in Africa
    Nathan Ford
    Medecins Sans Frontieres, Geneva, Switzerland
    Global Health 7:33. 2011
    ....
  17. doi request reprint Adverse events associated with nevirapine and efavirenz-based first-line antiretroviral therapy: a systematic review and meta-analysis
    Zara Shubber
    Department of Infectious Disease Epidemiology, Faculty of Medicine, Imperial College, London, UK
    AIDS 27:1403-12. 2013
    ..These two drugs are known to have differing toxicity profiles, but the risk of these toxicities overall is not well established...
  18. pmc Effectiveness of patient adherence groups as a model of care for stable patients on antiretroviral therapy in Khayelitsha, Cape Town, South Africa
    Miguel Ángel Luque-Fernández
    Centre for Infectious Disease Epidemiology and Research, School of Public Health and Family Medicine, University of Cape Town, Cape Town, South Africa
    PLoS ONE 8:e56088. 2013
    ..This study, in Khayelitsha, South Africa, evaluates the effectiveness of a group-based model of care run predominantly by non-clinical staff in retaining patients in care and maintaining adherence...
  19. pmc Systematic review of the use of dried blood spots for monitoring HIV viral load and for early infant diagnosis
    Pieter W Smit
    Department of Clinical Research, London School of Hygiene and Tropical Medicine, London, United Kingdom
    PLoS ONE 9:e86461. 2014
    ..We systematically reviewed evidence on the performance of DBS compared to plasma for VL monitoring and EID...
  20. pmc Nevirapine-associated early hepatotoxicity: incidence, risk factors, and associated mortality in a primary care ART programme in South Africa
    Kathryn M Chu
    South African Medical Unit, Medecins Sans Frontieres, Johannesburg, South Africa
    PLoS ONE 5:e9183. 2010
    ..One of the primary concerns with the use of this regimen is nevirapine-associated hepatotoxicity...
  21. doi request reprint Improving first-line antiretroviral therapy in resource-limited settings
    Nathan Ford
    Medecins Sans Frontieres, Medical Unit, Cape Town, South Africa
    Curr Opin HIV AIDS 5:38-47. 2010
    ..Newer medicines with greater potency and better safety profiles open the possibility for improving first-line antiretroviral therapy for developing countries...
  22. ncbi request reprint Distribution of antiretroviral treatment through self-forming groups of patients in Tete Province, Mozambique
    Tom Decroo
    Medecins Sans Frontieres, Tete, Mozambique
    J Acquir Immune Defic Syndr 56:e39-44. 2011
    ..Group members visit the health centre on a rotational basis, such that each group member has contact with the health service every 6 months...
  23. pmc Correcting for mortality among patients lost to follow up on antiretroviral therapy in South Africa: a cohort analysis
    Gilles Van Cutsem
    Medecins Sans Frontieres, Cape Town, South Africa
    PLoS ONE 6:e14684. 2011
    ..We describe LTF before and after correction for mortality in a primary care ART programme with linkages to the national vital registration system...
  24. ncbi request reprint Systematic review and meta-analysis: Patient and programme impact of fixed-dose combination antiretroviral therapy
    Rubeena Ramjan
    Department of Infectious Diseases, Faculty of Medicine, Imperial College, London, UK
    Trop Med Int Health 19:501-13. 2014
    ..To compare the advantages to patients and to programmes between fixed-dose combination (FDC) antiretroviral therapy and separate tablet regimens...
  25. doi request reprint Risk factors, barriers and facilitators for linkage to antiretroviral therapy care: a systematic review
    Darshini Govindasamy
    Medecins Sans Frontieres, Cape Town, South Africa
    AIDS 26:2059-67. 2012
    ..To characterize patient and programmatic factors associated with retention in care during the pre-antiretroviral therapy (ART) period and linkage to ART care...
  26. ncbi request reprint Safety of efavirenz in first-trimester of pregnancy: a systematic review and meta-analysis of outcomes from observational cohorts
    Nathan Ford
    Medecins Sans Frontieres, University of Cape Town, Cape Town, South Africa
    AIDS 24:1461-70. 2010
    ..Data on efavirenz safety in first trimester pregnancy are conflicting. We conducted a systematic review and meta-analysis of the available evidence from observational cohorts...
  27. pmc Early adherence to antiretroviral medication as a predictor of long-term HIV virological suppression: five-year follow up of an observational cohort
    Nathan Ford
    Medecins Sans Frontieres, Cape Town, South Africa
    PLoS ONE 5:e10460. 2010
    ..Previous studies have demonstrated a cross-sectional relationship between antiretroviral adherence and HIV virological suppression. We assessed the predictive value of baseline adherence in determining long-term virological failure...
  28. ncbi request reprint Safety of efavirenz in the first trimester of pregnancy: an updated systematic review and meta-analysis
    Nathan Ford
    aHIV Department, World Health Organization, Geneva, Switzerland bEunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Rockville, Maryland, USA cDepartment of Infectious Disease Epidemiology, Imperial College London, London, UK dHIV AIDS Unit, Infectious Disease Service, Geneva University Hospital eMédecins Sans Frontières, Geneva, Switzerland
    AIDS 28:S123-31. 2014
    ..The objective of this review is to update evidence on efavirenz safety in HIV-infected pregnant women to inform revision of the 2013 WHO guidelines for antiretroviral therapy in low and middle-income countries...
  29. ncbi request reprint Burden of HIV-related cytomegalovirus retinitis in resource-limited settings: a systematic review
    Nathan Ford
    Department of HIV AIDS, World Health Organization, Geneva, Switzerland
    Clin Infect Dis 57:1351-61. 2013
    ....
  30. doi request reprint Earlier initialization of highly active antiretroviral therapy is associated with long-term survival and is cost-effective: findings from a deterministic model of a 10-year Ugandan cohort
    Fergal P Mills
    Faculty of Health Sciences, University of Ottawa, Ottawa, Canada Médecins Sans Frontiers, Geneva, Switzerland
    J Acquir Immune Defic Syndr 61:364-9. 2012
    ..We examined costs of this shift using data from Uganda for almost 10 years...
  31. ncbi request reprint HIV viral load monitoring in resource-limited regions: optional or necessary?
    Alexandra Calmy
    Medecins Sans Frontieres, Access to Medicines Campaign, Geneva, 1211, Switzerland
    Clin Infect Dis 44:128-34. 2007
    ..Rather than considering viral load data to be an unaffordable luxury, efforts should be made to ensure that viral load testing becomes affordable, simple, and easy to use in resource-limited settings...
  32. pmc Treatment interruption in a primary care antiretroviral therapy program in South Africa: cohort analysis of trends and risk factors
    Katharina Kranzer
    The Desmond Tutu HIV Centre, Institute for Infectious Disease and Molecular Medicine, Faculty of Health Science, University of Cape Town, South Africa
    J Acquir Immune Defic Syndr 55:e17-23. 2010
    ..To investigate antiretroviral treatment (ART) interruption in a long-term treatment cohort in South Africa...
  33. ncbi request reprint Generic fixed-dose combination antiretroviral treatment in resource-poor settings: multicentric observational cohort
    Alexandra Calmy
    MSF, Campaign for Access to Essential Medicines, 78 rue de Lausanne, 1205 Geneva, Switzerland
    AIDS 20:1163-9. 2006
    ..The use fixed-dose combination (FDC) is a critical tool in improving HAART. Studies on the effectiveness of combined lamivudine, stavudine and nevirapine (3TC/d4T/NVP) are scarce...
  34. doi request reprint Drug-resistant tuberculosis: time for visionary political leadership
    Ibrahim Abubakar
    Centre for Infectious Disease Epidemiology, Department of Infection and Population Health, University College London, London, UK
    Lancet Infect Dis 13:529-39. 2013
    ..Visionary political leadership is needed to curb the rise of MDR and XDR tuberculosis worldwide, through sustained funding and the implementation of global and regional action plans...
  35. ncbi request reprint Association between older age and adverse outcomes on antiretroviral therapy: a cohort analysis of programme data from nine countries
    Jane Greig
    Medecins Sans Frontieres, London, UK
    AIDS 26:S31-7. 2012
    ..We report on the associations between older age and adverse outcomes in HIV/AIDS antiretroviral programmes across 17 programmes in sub-Saharan Africa...
  36. ncbi request reprint Unstructured treatment interruption of antiretroviral therapy in clinical practice: a systematic review
    Katharina Kranzer
    Department of Clinical Research, London School of Hygiene and Tropical Medicine, London, UK
    Trop Med Int Health 16:1297-313. 2011
    ..To characterize the frequency, reasons, risk factors, and consequences of unstructured anti-retroviral treatment interruptions...
  37. pmc Quantifying and addressing losses along the continuum of care for people living with HIV infection in sub-Saharan Africa: a systematic review
    Katharina Kranzer
    Department of Clinical Research, London School of Hygiene and Tropical Medicine, Faculty of Infectious and Tropical Diseases, London, United Kingdom
    J Int AIDS Soc 15:17383. 2012
    ..This review aims to quantify patients along the continuum of care in sub-Saharan Africa and review possible interventions...
  38. pmc Cesarean section rates and indications in sub-Saharan Africa: a multi-country study from Medecins sans Frontieres
    Kathryn Chu
    Medecins Sans Frontieres, Johannesburg, South Africa
    PLoS ONE 7:e44484. 2012
    ..This study reports Cesarean sections rates and indications in Democratic Republic of Congo, Burundi, and Sierra Leone, and describe the main parameters associated with maternal and early neonatal mortality...
  39. pmc A three-tier framework for monitoring antiretroviral therapy in high HIV burden settings
    Meg Osler
    Centre for Infectious Diseases, Epidemiology and Research, School of Public Health and Family Medicine, University of Cape Town, Cape Town, South Africa
    J Int AIDS Soc 17:18908. 2014
    ....
  40. pmc Comparative efficacy of Lamivudine and emtricitabine: a systematic review and meta-analysis of randomized trials
    Nathan Ford
    Department of HIV AIDS, World Health Organization, Geneva, Switzerland
    PLoS ONE 8:e79981. 2013
    ..Lamivudine and emtricitabine are considered equivalent by several guidelines, but evidence of comparable efficacy is conflicting...
  41. pmc Antiretroviral therapy outcomes among adolescents and youth in rural Zimbabwe
    Helen Bygrave
    Southern Africa Medical Unit, Medecins Sans Frontieres, Cape Town, South Africa
    PLoS ONE 7:e52856. 2012
    ..70, 95%CI 1.62-4.52). This study highlights the need for adapted adherence support and service delivery models for both adolescents and young adults...
  42. doi request reprint Similar mortality and reduced loss to follow-up in integrated compared with vertical programs providing antiretroviral treatment in sub-saharan Africa
    Jane Greig
    Manson Unit, Medecins Sans Frontieres, Saffron Hill, London, UK
    J Acquir Immune Defic Syndr 59:e92-8. 2012
    ..We analyzed the survival probability among patients receiving antiretroviral therapy (ART) from 2003 to 2010 in integrated versus vertical programs in 9 countries in sub-Saharan Africa...
  43. pmc Challenges and opportunities for the implementation of virological testing in resource-limited settings
    Teri Roberts
    Medecins Sans Frontieres Access Campaign, Geneva, Switzerland
    J Int AIDS Soc 15:17324. 2012
    ....
  44. doi request reprint How developing world concerns need to be part of drug development plans: a case study of four emerging antiretrovirals
    Jens Van Roey
    Medecins Sans Frontieres, Campaign for Access to Essential Medecins, Rue de Lausanne 78, 1211 Geneva, Switzerland
    Drug Discov Today 13:601-5. 2008
    ..Key research questions relevant for developing countries need to be answered early in the drug development process to ensure maximum benefit for the majority...
  45. doi request reprint Seven-year experience of a primary care antiretroviral treatment programme in Khayelitsha, South Africa
    Andrew Boulle
    School of Public Health and Family Medicine, University of Cape Town, Anzio Road, Cape Town, South Africa
    AIDS 24:563-72. 2010
    ..We report on outcomes after 7 years of a community-based antiretroviral therapy (ART) programme in Khayelitsha, South Africa, with death registry linkages to correct for mortality under-ascertainment...
  46. pmc An integrated approach of community health worker support for HIV/AIDS and TB care in Angónia district, Mozambique
    Sandrine Simon
    , Maputo, Mozambique
    BMC Int Health Hum Rights 9:13. 2009
    ..CONCLUSION: The community health team has several advantages over 'disease-specific' community health worker approaches in terms of accountability, acceptability, and expanded access to care...
  47. pmc Ethics of conducting research in conflict settings
    Nathan Ford
    , Johannesburg, South Africa
    Confl Health 3:7. 2009
    ..Special attention needs to be placed on the feasibility and necessity of doing research in conflict-settings, and the harm-benefit ratio for potential research participants...
  48. pmc Mortality, violence and access to care in two districts of Port-au-Prince, Haiti
    Frederique Ponsar
    Medecins Sans Frontieres, 94 Rue Dupre, Brussels, Belgium
    Confl Health 3:4. 2009
    ..Towards the end of 2006 open conflict broke out between United Nations forces and armed militia in Port-au-Prince, Haiti. Fighting was most intense in the district of Cité Soleil...
  49. ncbi request reprint Slow response to Angola's food crisis
    Nathan Ford
    Medecins Sans Frontieres, 124 32 Clerkenwell Road, London EC1R 5DJ, UK
    Lancet 360:334-6. 2002
  50. ncbi request reprint WHO must defend patients' interests, not industry
    Paul Cawthorne
    Medecins Sans Frontieres, Bangkok 10240, Thailand
    Lancet 369:974-5. 2007
  51. ncbi request reprint Do aid agencies have an ethical duty to comply with researchers? A response to Rennie
    Rony Zachariah
    Medecins Sans Frontieres, 68 Rue de Gasperich, L 1617, Gasperich, Luxembourg
    Dev World Bioeth 6:78-80. 2006
    ....
  52. doi request reprint Operative mortality in resource-limited settings: the experience of Medecins Sans Frontieres in 13 countries
    Kathryn M Chu
    Department of Surgery, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    Arch Surg 145:721-5. 2010
    ..To determine operative mortality in surgical programs from resource-limited settings...
  53. doi request reprint Implementing a tenofovir-based first-line regimen in rural Lesotho: clinical outcomes and toxicities after two years
    Helen Bygrave
    Medecins Sans Frontieres, Morija, Lesotho
    J Acquir Immune Defic Syndr 56:e75-8. 2011
    ..We report on outcomes and toxicities among patients on these different regimens in a routine treatment cohort in Lesotho...
  54. pmc Renal safety of a tenofovir-containing first line regimen: experience from an antiretroviral cohort in rural Lesotho
    Helen Bygrave
    Medecins Sans Frontieres, Morija, Lesotho
    PLoS ONE 6:e17609. 2011
    ..We report prevalence of abnormal renal function at baseline and factors associated with abnormal renal function from a community cohort in Lesotho...
  55. pmc Public health and company wealth
    Nathan Ford
    Medecins Sans Frontieres, London EC1N 8QX
    BMJ 326:1296. 2003
  56. ncbi request reprint Mortality, violence and lack of access to healthcare in the Democratic Republic of Congo
    Michel van Herp
    Disasters 27:141-53. 2003
    ..Infectious-disease control and treatment are a priority, as is increasing access to health-care. Humanitarian assistance must be increased considerably, especially in rural areas and zones that have been affected directly by conflict...
  57. ncbi request reprint The role of civil society in protecting public health over commercial interests: lessons from Thailand
    Nathan Ford
    Medecins Sans Frontieres, Ladphrao, Klongchan Bangkapi, Bangkok, Thailand
    Lancet 363:560-3. 2004
  58. ncbi request reprint Sustaining access to antiretroviral therapy in the less-developed world: lessons from Brazil and Thailand
    Nathan Ford
    Medecins Sans Frontieres, 522 Mooban Nakorn Thai 14, Ladphrao Soi 101 1, Bangkok 10240, Thailand
    AIDS 21:S21-9. 2007
    ..LOCAL PRODUCTION OF AFFORDABLE, NON-PATENTED DRUGS: Many older antiretroviral drugs are not patented in either country and affordable generic versions are manufactured by local pharmaceutical institutes...
  59. pmc Addressing psychosocial needs in the aftermath of the tsunami
    Kaz de Jong
    PLoS Med 2:e179. 2005
  60. ncbi request reprint Registration problems for antiretrovirals in Africa
    Nathan Ford
    Medecins Sans Frontieres, Khayelitsha, 7784 South Africa
    Lancet 367:794-5. 2006
  61. ncbi request reprint Safety of cotrimoxazole in pregnancy: a systematic review and meta-analysis
    Nathan Ford
    Department of HIV AIDS, World Health Organization, Geneva, Switzerland Department of Infectious Disease Epidemiology, Faculty of Medicine, Imperial College, London, United Kingdom Department of Medicine, Divisions of Infectious Diseases and General Internal Medicine, Icahn School of Medicine at Mount Sinai, New York, NY ICAP, Mailman School of Public Health, and College of Physicians and Surgeons, Columbia University, New York, NY Department of Paediatrics and Child Health, Tygerberg Hospital, University of Stellenbosch, Cape Town South Africa and Maternal and Pediatric Infectious Disease Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Rockville, MD
    J Acquir Immune Defic Syndr 66:512-21. 2014
    ..Some reports suggest that fetuses exposed to cotrimoxazole during early pregnancy may have an increased risk of congenital anomalies. We carried out this systematic review to update the evidence of cotrimoxazole safety in pregnancy...
  62. ncbi request reprint The 2013 WHO guidelines for antiretroviral therapy: evidence-based recommendations to face new epidemic realities
    Meg Doherty
    HIV Department, World Health Organization, Geneva, Switzerland
    Curr Opin HIV AIDS 8:528-34. 2013
    ..The review summarizes the key new recommendations of the WHO 2013 guidelines for antiretroviral therapy and describes the potential impact of these recommendations on the HIV epidemic...
  63. doi request reprint Treatment outcomes from the largest antiretroviral treatment program in Myanmar (Burma): a cohort analysis of retention after scale-up
    Kalpana Sabapathy
    Imperial College London, London, United Kingdom
    J Acquir Immune Defic Syndr 60:e53-62. 2012
    ..Antiretroviral treatment (ART) coverage in Myanmar is well below average. This study describes retention and baseline predictors of prognosis from the largest ART program in the country...
  64. doi request reprint Viral load monitoring as a tool to reinforce adherence: a systematic review
    Kimberly Bonner
    Access Campaign, Medecins Sans Frontieres, Geneva, Switzerland
    J Acquir Immune Defic Syndr 64:74-8. 2013
    ..Viral load monitoring has been proposed as a tool to reinforce adherence, but outcomes have never been systematically assessed...
  65. pmc Uptake of home-based voluntary HIV testing in sub-Saharan Africa: a systematic review and meta-analysis
    Kalpana Sabapathy
    London School of Hygiene and Tropical Medicine, London, UK
    PLoS Med 9:e1001351. 2012
    ..Improving access to HIV testing is a key priority in scaling up HIV treatment and prevention services. Home-based voluntary counselling and testing (HBT) as an approach to delivering wide-scale HIV testing is explored here...
  66. doi request reprint Scaling up antiretroviral therapy in resource-limited settings: adapting guidance to meet the challenges
    Marco Vitoria
    Department of HIV AIDS, World Health Organization, Geneva, Switzerland
    Curr Opin HIV AIDS 8:12-8. 2013
    ....
  67. doi request reprint Task shifting for the delivery of pediatric antiretroviral treatment: a systematic review
    Martina Penazzato
    HIV AIDS Department, World Health Organization, Geneva, Switzerland Centre for Infectious Disease Epidemiology and Research, University of Cape Town, Cape Town, South Africa and HIV and AIDS Department, Ministry of Health and Social Welfare, Harare, Zimbabwe
    J Acquir Immune Defic Syndr 65:414-22. 2014
    ..Task shifting is an effective approach broadly used for adults, which some countries have also adopted for children, but implementation is limited by lack of confidence and skills among nonspecialist staff...
  68. doi request reprint Outcomes of clofazimine for the treatment of drug-resistant tuberculosis: a systematic review and meta-analysis
    Teesta Dey
    Faculty of Medicine, Imperial College, London, UK
    J Antimicrob Chemother 68:284-93. 2013
    ..It has been proposed that repurposing clofazimine for DR-TB treatment might be one way to increase therapeutic options...
  69. pmc Modelling the strategic use of antiretroviral therapy for the treatment and prevention of HIV
    Nathan Ford
    HIV AIDS Department, World Health Organization, Geneva, Switzerland
    PLoS Med 10:e1001535. 2013
    b>Nathan Ford and Gottfried Hirnschall reflect on recent research by Jan Hontelez and colleagues published in this week's PLOS Medicine...
  70. pmc Improving effective surgical delivery in humanitarian disasters: lessons from Haiti
    Kathryn Chu
    Medecins Sans Frontieres, Cape Town, South Africa
    PLoS Med 8:e1001025. 2011
    ..Kathryn Chu and colleagues describe the experiences of Médecins sans Frontières after the 2010 Haiti earthquake, and discuss how to improve delivery of surgery in humanitarian disasters...
  71. doi request reprint Risk factors for mortality in AIDS-associated Kaposi sarcoma in a primary care antiretroviral treatment program in Malawi
    Kathryn Chu
    Medecins Sans Frontieres, 49 Jorissen St, Braamfontein 2017, Johannesburg, South Africa
    Int Health 2:99-102. 2010
    ..A CD4 count ≤150 cells/μl, advanced stage AIDS-KS, and absence of bleomycin chemotherapy were associated with increased mortality. Earlier diagnosis and improved treatment of AIDS-KS are urgently needed in order to reduce mortality. ..
  72. doi request reprint Feasibility and benefits of scaling up antiretroviral treatment provision with the 2010 WHO antiretroviral therapy guidelines in rural Lesotho
    Helen Bygrave
    South African Medical Unit, Medecins Sans Frontieres, PO Box 27401, Rhine Road, Sea Point 8050, Cape Town, South Africa
    Int Health 4:170-5. 2012
    ..This experience demonstrates that, despite limited resources, it was feasible to provide a standard of care similar to that of western guidelines and that these changes were supportive of simplified patient management. ..
  73. doi request reprint Treatment outcomes of patients on second-line antiretroviral therapy in resource-limited settings: a systematic review and meta-analysis
    Olawale Ajose
    Clinton Health Access Initiative, Dar es Salaam, Tanzania
    AIDS 26:929-38. 2012
    ..We carried out a systematic review in order to summarize reported rates and reasons for virological failure among people on second-line therapy in resource-limited settings...
  74. ncbi request reprint Implementing antiretroviral therapy in rural communities: the Lusikisiki model of decentralized HIV/AIDS care
    Martha Bedelu
    Medecins Sans Frontieres, Lusikisiki, South Africa
    J Infect Dis 196:S464-8. 2007
    ..Maintaining quality and coverage will require increased resource input from the public sector and full acceptance of creative approaches to implementation, including task shifting and community involvement...
  75. doi request reprint Directly observed antiretroviral therapy: a systematic review and meta-analysis of randomised clinical trials
    Nathan Ford
    Medecins Sans Frontieres, Cape Town, Western Cape, South Africa
    Lancet 374:2064-71. 2009
    ..We did a systematic review and meta-analysis of randomised trials of directly observed versus self-administered antiretroviral treatment...
  76. pmc Towards universal voluntary HIV testing and counselling: a systematic review and meta-analysis of community-based approaches
    Amitabh B Suthar
    Department of HIV AIDS, World Health Organization, Geneva, Switzerland
    PLoS Med 10:e1001496. 2013
    ..Facility-based HTC, while essential, is unlikely to meet national and global targets on its own. This article systematically reviews the evidence for community-based HTC...
  77. pmc Impact of point-of-care CD4 testing on linkage to HIV care: a systematic review
    Elke Wynberg
    Department of Infectious Diseases, Faculty of Medicine, Imperial College London, South Kensington, London, UK
    J Int AIDS Soc 17:18809. 2014
    ..In this review, we assess the available evidence on the patient and programme impact of point-of-care CD4 testing...
  78. pmc Systematic review of the performance of HIV viral load technologies on plasma samples
    Kimberly A Sollis
    Department of Clinical Research, London School of Hygiene and Tropical Medicine, London, United Kingdom
    PLoS ONE 9:e85869. 2014
    ..Since 2010 the World Health Organization has recommended a phase-in approach to VL monitoring in resource-limited settings. We conducted a systematic review of the accuracy and precision of HIV VL technologies for treatment monitoring...
  79. doi request reprint Adherence to HIV post-exposure prophylaxis in victims of sexual assault: a systematic review and meta-analysis
    Liza Chacko
    Imperial College London, St Mary s Hospital, London, UK
    Sex Transm Infect 88:335-41. 2012
    ..To assess adherence to post-exposure prophylaxis (PEP) for the prevention of HIV infection in victims of sexual assault...
  80. doi request reprint Drug-resistant tuberculosis--current dilemmas, unanswered questions, challenges, and priority needs
    Alimuddin Zumla
    University College London, Centre for Clinical Microbiology, Division of Infection and Immunity, London, UK
    J Infect Dis 205:S228-40. 2012
    ....
  81. pmc Surgical care for the direct and indirect victims of violence in the eastern Democratic Republic of Congo
    Kathryn Chu
    Medecins Sans Frontieres, 49 Jorrisen St, Braamfontein 2017, Johannesburg, South Africa
    Confl Health 4:6. 2010
    ..In this paper we report on surgical interventions carried out by Médecins sans Frontières in Masisi, North Kivu, Democratic Republic of Congo to contribute to the scarce evidence base on surgical needs in conflict...
  82. pmc Lessons learned during down referral of antiretroviral treatment in Tete, Mozambique
    Tom Decroo
    South African Medical Unit, Medecins Sans Frontieres, Johannesburg, South Africa
    J Int AIDS Soc 12:6. 2009
    ..Down referral can be avoided by initiating patients' antiretroviral treatment at clinic level from the outset...
  83. pmc Simplified ART Delivery Models Are Needed for the Next Phase of Scale Up
    Nathan Ford
    Medecins Sans Frontieres, Geneva, Switzerland
    PLoS Med 8:e1001060. 2011
    b>Nathan Ford and Edward Mills discuss broader issues in HIV care delivery raised by research carried out by Lawrence Long and colleagues into down-shifting HIV care to primary health facilities.
  84. pmc When to start antiretroviral therapy in resource-limited settings: a human rights analysis
    Nathan Ford
    Medecins Sans Frontieres, Cape Town, South Africa
    BMC Int Health Hum Rights 10:6. 2010
    ....