Lessons learned during down referral of antiretroviral treatment in Tete, MozambiqueTom Decroo
South African Medical Unit, Medecins Sans Frontieres, Johannesburg, South Africa
J Int AIDS Soc 12:6. 2009
..Down referral can be avoided by initiating patients' antiretroviral treatment at clinic level from the outset...
Keeping health staff healthy: evaluation of a workplace initiative to reduce morbidity and mortality from HIV/AIDS in MalawiMarielle Bemelmans
Medecins Sans Frontieres, Belgium, Thyolo, Malawi
J Int AIDS Soc 14:1. 2011
....
Antiretroviral treatment outcomes from a nurse-driven, community-supported HIV/AIDS treatment programme in rural Lesotho: observational cohort assessment at two yearsRachel Cohen
Medecins Sans Frontieres, Morija, Lesotho
J Int AIDS Soc 12:23. 2009
..abstract:..
AIDS-associated Kaposi's sarcoma is linked to advanced disease and high mortality in a primary care HIV programme in South AfricaKathryn M Chu
Medecins Sans Frontieres, Braamfontein, Johannesburg, South Africa
J Int AIDS Soc 13:23. 2010
..In African cohorts, however, mortality remains high. In this study, we describe disease characteristics and risk factors for mortality in a public sector HIV programme in South Africa...
A systematic review of task- shifting for HIV treatment and care in AfricaMike Callaghan
Department of Anthropology, University of Toronto, Canada
Hum Resour Health 8:8. 2010
..Task shifting should be considered for careful implementation where HRH shortages threaten rollout programmes...
Surgical care for the direct and indirect victims of violence in the eastern Democratic Republic of CongoKathryn Chu
Medecins Sans Frontieres, 49 Jorrisen St, Braamfontein 2017, Johannesburg, South Africa
Confl Health 4:6. 2010
..In this paper we report on surgical interventions carried out by Médecins sans Frontières in Masisi, North Kivu, Democratic Republic of Congo to contribute to the scarce evidence base on surgical needs in conflict...
An integrated approach of community health worker support for HIV/AIDS and TB care in Angónia district, MozambiqueSandrine Simon
, Maputo, Mozambique
BMC Int Health Hum Rights 9:13. 2009
..CONCLUSION: The community health team has several advantages over 'disease-specific' community health worker approaches in terms of accountability, acceptability, and expanded access to care...
When to start antiretroviral therapy in resource-limited settings: a human rights analysisNathan Ford
Medecins Sans Frontieres, Cape Town, South Africa
BMC Int Health Hum Rights 10:6. 2010
....
Safety of efavirenz in first-trimester of pregnancy: a systematic review and meta-analysis of outcomes from observational cohortsNathan Ford
Medecins Sans Frontieres, University of Cape Town, Cape Town, South Africa
AIDS 24:1461-70. 2010
..Data on efavirenz safety in first trimester pregnancy are conflicting. We conducted a systematic review and meta-analysis of the available evidence from observational cohorts...
Early adherence to antiretroviral medication as a predictor of long-term HIV virological suppression: five-year follow up of an observational cohortNathan Ford
Medecins Sans Frontieres, Cape Town, South Africa
PLoS ONE 5:e10460. 2010
..Previous studies have demonstrated a cross-sectional relationship between antiretroviral adherence and HIV virological suppression. We assessed the predictive value of baseline adherence in determining long-term virological failure...
Ethics of conducting research in conflict settingsNathan Ford
, Johannesburg, South Africa
Confl Health 3:7. 2009
..Special attention needs to be placed on the feasibility and necessity of doing research in conflict-settings, and the harm-benefit ratio for potential research participants...
Directly observed antiretroviral therapy: a systematic review and meta-analysis of randomised clinical trialsNathan Ford
Medecins Sans Frontieres, Cape Town, Western Cape, South Africa
Lancet 374:2064-71. 2009
..We did a systematic review and meta-analysis of randomised trials of directly observed versus self-administered antiretroviral treatment...
Improving first-line antiretroviral therapy in resource-limited settingsNathan Ford
Medecins Sans Frontieres, Medical Unit, Cape Town, South Africa
Curr Opin HIV AIDS 5:38-47. 2010
..Newer medicines with greater potency and better safety profiles open the possibility for improving first-line antiretroviral therapy for developing countries...
Correcting for mortality among patients lost to follow up on antiretroviral therapy in South Africa: a cohort analysisGilles Van Cutsem
Medecins Sans Frontieres, Cape Town, South Africa
PLoS ONE 6:e14684. 2011
..We describe LTF before and after correction for mortality in a primary care ART programme with linkages to the national vital registration system...
Safety of efavirenz in the first trimester of pregnancy: an updated systematic review and meta-analysisNathan Ford
Centre for Infectious Disease Epidemiology and Research, University of Cape Town, Cape Town, South Africa
AIDS 25:2301-4. 2011
..85 (95% CI 0.61-1.20). One neural tube defect was observed (myelomeningocele), giving an incidence of 0.07% (95% CI 0.002-0.39)...
Treatment interruption in a primary care antiretroviral therapy program in South Africa: cohort analysis of trends and risk factorsKatharina Kranzer
The Desmond Tutu HIV Centre, Institute for Infectious Disease and Molecular Medicine, Faculty of Health Science, University of Cape Town, South Africa
J Acquir Immune Defic Syndr 55:e17-23. 2010
..To investigate antiretroviral treatment (ART) interruption in a long-term treatment cohort in South Africa...
Nevirapine-associated early hepatotoxicity: incidence, risk factors, and associated mortality in a primary care ART programme in South AfricaKathryn M Chu
South African Medical Unit, Medecins Sans Frontieres, Johannesburg, South Africa
PLoS ONE 5:e9183. 2010
..One of the primary concerns with the use of this regimen is nevirapine-associated hepatotoxicity...
Early initiation of antiretroviral therapy and associated reduction in mortality, morbidity and defaulting in a nurse-managed, community cohort in LesothoNathan Ford
Medecins Sans Frontieres, University of Cape Town, South Africa
AIDS 24:2645-50. 2010
..Lesotho has supported earlier initiation since 2008. We assessed outcomes comparing early (CD4 cell counts >200 cells/μl) and late (CD4 cell counts ≤200 cells/μl) initiation...
Seven-year experience of a primary care antiretroviral treatment programme in Khayelitsha, South AfricaAndrew Boulle
School of Public Health and Family Medicine, University of Cape Town, Anzio Road, Cape Town, South Africa
AIDS 24:563-72. 2010
..We report on outcomes after 7 years of a community-based antiretroviral therapy (ART) programme in Khayelitsha, South Africa, with death registry linkages to correct for mortality under-ascertainment...
Effectiveness of patient adherence groups as a model of care for stable patients on antiretroviral therapy in Khayelitsha, Cape Town, South AfricaMiguel Ángel Luque-Fernández
Centre for Infectious Disease Epidemiology and Research, School of Public Health and Family Medicine, University of Cape Town, Cape Town, South Africa
PLoS ONE 8:e56088. 2013
..This study, in Khayelitsha, South Africa, evaluates the effectiveness of a group-based model of care run predominantly by non-clinical staff in retaining patients in care and maintaining adherence...
Unstructured treatment interruption of antiretroviral therapy in clinical practice: a systematic reviewKatharina Kranzer
Department of Clinical Research, London School of Hygiene and Tropical Medicine, London, UK
Trop Med Int Health 16:1297-313. 2011
..To characterize the frequency, reasons, risk factors, and consequences of unstructured anti-retroviral treatment interruptions...
Implementing a tenofovir-based first-line regimen in rural Lesotho: clinical outcomes and toxicities after two yearsHelen Bygrave
Medecins Sans Frontieres, Morija, Lesotho
J Acquir Immune Defic Syndr 56:e75-8. 2011
..We report on outcomes and toxicities among patients on these different regimens in a routine treatment cohort in Lesotho...
Operative mortality in resource-limited settings: the experience of Medecins Sans Frontieres in 13 countriesKathryn M Chu
Department of Surgery, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
Arch Surg 145:721-5. 2010
..To determine operative mortality in surgical programs from resource-limited settings...
The first decade of antiretroviral therapy in AfricaNathan Ford
Medecins Sans Frontieres, Geneva, Switzerland
Global Health 7:33. 2011
....
Renal safety of a tenofovir-containing first line regimen: experience from an antiretroviral cohort in rural LesothoHelen Bygrave
Medecins Sans Frontieres, Morija, Lesotho
PLoS ONE 6:e17609. 2011
..We report prevalence of abnormal renal function at baseline and factors associated with abnormal renal function from a community cohort in Lesotho...
Registration problems for antiretrovirals in AfricaNathan Ford
, Khayelitsha, 7784 South Africa
Lancet 367:794-5. 2006
Slow response to Angola's food crisisNathan Ford
, 124-32 Clerkenwell Road, London EC1R 5DJ, UK
Lancet 360:334-6. 2002
Public health and company wealthNathan Ford
, London EC1N 8QX
BMJ 326:1296. 2003
Mortality, violence and lack of access to healthcare in the Democratic Republic of CongoMichel van Herp
Disasters 27:141-53. 2003
..Infectious-disease control and treatment are a priority, as is increasing access to health-care. Humanitarian assistance must be increased considerably, especially in rural areas and zones that have been affected directly by conflict...
The role of civil society in protecting public health over commercial interests: lessons from ThailandNathan Ford
, Ladphrao, Klongchan Bangkapi, Bangkok, Thailand
Lancet 363:560-3. 2004
Addressing psychosocial needs in the aftermath of the tsunamiKaz de Jong
PLoS Med 2:e179. 2005
Do aid agencies have an ethical duty to comply with researchers? A response to RennieRony Zachariah
Medecins Sans Frontieres, 68 Rue de Gasperich, L 1617, Gasperich, Luxembourg
Dev World Bioeth 6:78-80. 2006
....
WHO must defend patients' interests, not industryPaul Cawthorne
, Bangkok 10240, Thailand
Lancet 369:974-5. 2007
Mortality, violence and access to care in two districts of Port-au-Prince, HaitiFrederique Ponsar
Medecins Sans Frontieres, 94 Rue Dupre, Brussels, Belgium
Confl Health 3:4. 2009
..Towards the end of 2006 open conflict broke out between United Nations forces and armed militia in Port-au-Prince, Haiti. Fighting was most intense in the district of Cité Soleil...
Sustaining access to antiretroviral therapy in the less-developed world: lessons from Brazil and ThailandNathan Ford
Medecins Sans Frontieres, 522 Mooban Nakorn Thai 14, Ladphrao Soi 101 1, Bangkok 10240, Thailand
AIDS 21:S21-9. 2007
..An informed and engaged civil society is essential to support governments in putting health before trade...
Cesarean section rates and indications in sub-Saharan Africa: a multi-country study from Medecins sans FrontieresKathryn Chu
Medecins Sans Frontieres, Johannesburg, South Africa
PLoS ONE 7:e44484. 2012
..This study reports Cesarean sections rates and indications in Democratic Republic of Congo, Burundi, and Sierra Leone, and describe the main parameters associated with maternal and early neonatal mortality...
Distribution of antiretroviral treatment through self-forming groups of patients in tete province, mozambiqueTom Decroo
From the Médecins Sans Frontières, Tete, Mozambique Médecins Sans Frontières, Maputo, Mozambique Provincial Health Department, Tete, Mozambique Médecins Sans Frontières, Cape Town, South Africa Department of International Health, Johns Hopkins School of Public Health, Baltimore, MD and Centre for Infectious Disease Epidemiology and Research, University of Cape Town, Cape Town, South Africa
J Acquir Immune Defic Syndr 56:e39-44. 2011
..Group members visit the health centre on a rotational basis, such that each group member has contact with the health service every 6 months...
Quantifying and addressing losses along the continuum of care for people living with HIV infection in sub-Saharan Africa: a systematic reviewKatharina Kranzer
Department of Clinical Research, London School of Hygiene and Tropical Medicine, Faculty of Infectious and Tropical Diseases, London, United Kingdom
J Int AIDS Soc 15:17383. 2012
..This review aims to quantify patients along the continuum of care in sub-Saharan Africa and review possible interventions...
Antiretroviral therapy outcomes among adolescents and youth in rural ZimbabweHelen Bygrave
Southern Africa Medical Unit, Medecins Sans Frontieres, Cape Town, South Africa
PLoS ONE 7:e52856. 2012
..70, 95%CI 1.62-4.52). This study highlights the need for adapted adherence support and service delivery models for both adolescents and young adults...
Safety of task-shifting for male medical circumcision: a systematic review and meta-analysisNathan Ford
Centre for Infectious Disease Epidemiology and Research, University of Cape Town, Cape Town, South Africa
AIDS 26:559-66. 2012
..We undertook a systematic review and meta-analysis to review the safety of task-shifting for circumcision in Africa...
Treatment outcomes of patients on second-line antiretroviral therapy in resource-limited settings: a systematic review and meta-analysisOlawale Ajose
Clinton Health Access Initiative, Dar es Salaam, Tanzania
AIDS 26:929-38. 2012
..We carried out a systematic review in order to summarize reported rates and reasons for virological failure among people on second-line therapy in resource-limited settings...
Risk factors, barriers and facilitators for linkage to antiretroviral therapy care: a systematic reviewDarshini Govindasamy
Medecins Sans Frontieres, Cape Town, South Africa
AIDS 26:2059-67. 2012
..To characterize patient and programmatic factors associated with retention in care during the pre-antiretroviral therapy (ART) period and linkage to ART care...
Implementing antiretroviral therapy in rural communities: the Lusikisiki model of decentralized HIV/AIDS careMartha Bedelu
Medecins Sans Frontieres, Lusikisiki, South Africa
J Infect Dis 196:S464-8. 2007
..Maintaining quality and coverage will require increased resource input from the public sector and full acceptance of creative approaches to implementation, including task shifting and community involvement...