Marilyn G Wiebe

Summary

Affiliation: VTT Biotechnology
Country: Finland

Publications

  1. pmc Bioconversion of D-galacturonate to keto-deoxy-L-galactonate (3-deoxy-L-threo-hex-2-ulosonate) using filamentous fungi
    Marilyn G Wiebe
    VTT Technical Research Centre of Finland, P, O, Box 1000, FI 02044 VTT, Finland
    BMC Biotechnol 10:63. 2010
  2. pmc Lipid production in batch and fed-batch cultures of Rhodosporidium toruloides from 5 and 6 carbon carbohydrates
    Marilyn G Wiebe
    VTT Technical Research Centre of Finland, PO Box 1000, Espoo, FI 02044 VTT, Finland
    BMC Biotechnol 12:26. 2012
  3. pmc Correlation of gene expression and protein production rate - a system wide study
    Mikko Arvas
    VTT Technical Research Centre of Finland, Tietotie 2, P, O, Box FI 1000, 02044 VTT, Espoo, Finland
    BMC Genomics 12:616. 2011
  4. pmc Oxygen dependence of metabolic fluxes and energy generation of Saccharomyces cerevisiae CEN.PK113-1A
    Paula Jouhten
    VTT Technical Research Centre of Finland, Espoo, Finland
    BMC Syst Biol 2:60. 2008
  5. pmc Transcriptional monitoring of steady state and effects of anaerobic phases in chemostat cultures of the filamentous fungus Trichoderma reesei
    Jari J Rautio
    VTT Technical Research Centre of Finland, Tietotie 2, Espoo, P, O, Box 1000, 02044 VTT Espoo, Finland
    BMC Genomics 7:247. 2006
  6. ncbi request reprint Central carbon metabolism of Saccharomyces cerevisiae in anaerobic, oxygen-limited and fully aerobic steady-state conditions and following a shift to anaerobic conditions
    Marilyn G Wiebe
    VTT Technical Research Centre of Finland, Finland
    FEMS Yeast Res 8:140-54. 2008
  7. pmc Low oxygen levels as a trigger for enhancement of respiratory metabolism in Saccharomyces cerevisiae
    Eija Rintala
    VTT Technical Research Centre of Finland, P, O, Box 1000, FI 02044 VTT, Finland
    BMC Genomics 10:461. 2009
  8. pmc Engineering filamentous fungi for conversion of D-galacturonic acid to L-galactonic acid
    Joosu Kuivanen
    VTT Technical Research Centre of Finland, Espoo, Finland
    Appl Environ Microbiol 78:8676-83. 2012
  9. pmc Transcription of hexose transporters of Saccharomyces cerevisiae is affected by change in oxygen provision
    Eija Rintala
    VTT, Technical Research Centre of Finland, PO Box 1000, FI 02044 VTT, Finland
    BMC Microbiol 8:53. 2008
  10. pmc Transcriptional responses of Saccharomyces cerevisiae to shift from respiratory and respirofermentative to fully fermentative metabolism
    Eija Rintala
    VTT Technical Research Centre of Finland, Finland
    OMICS 15:461-76. 2011

Collaborators

Detail Information

Publications19

  1. pmc Bioconversion of D-galacturonate to keto-deoxy-L-galactonate (3-deoxy-L-threo-hex-2-ulosonate) using filamentous fungi
    Marilyn G Wiebe
    VTT Technical Research Centre of Finland, P, O, Box 1000, FI 02044 VTT, Finland
    BMC Biotechnol 10:63. 2010
    ..Keto-deoxy-L-galactonate is a natural intermediate in the fungal D-galacturonate metabolic pathway, and thus keto-deoxy-L-galactonate can be produced in a simple biological conversion...
  2. pmc Lipid production in batch and fed-batch cultures of Rhodosporidium toruloides from 5 and 6 carbon carbohydrates
    Marilyn G Wiebe
    VTT Technical Research Centre of Finland, PO Box 1000, Espoo, FI 02044 VTT, Finland
    BMC Biotechnol 12:26. 2012
    ....
  3. pmc Correlation of gene expression and protein production rate - a system wide study
    Mikko Arvas
    VTT Technical Research Centre of Finland, Tietotie 2, P, O, Box FI 1000, 02044 VTT, Espoo, Finland
    BMC Genomics 12:616. 2011
    ..Interestingly, it exhibits a low growth rate protein production phenotype...
  4. pmc Oxygen dependence of metabolic fluxes and energy generation of Saccharomyces cerevisiae CEN.PK113-1A
    Paula Jouhten
    VTT Technical Research Centre of Finland, Espoo, Finland
    BMC Syst Biol 2:60. 2008
    ..Oxygen is a major determinant of the physiology of S. cerevisiae but understanding of the oxygen dependence of intracellular flux distributions is still scarce...
  5. pmc Transcriptional monitoring of steady state and effects of anaerobic phases in chemostat cultures of the filamentous fungus Trichoderma reesei
    Jari J Rautio
    VTT Technical Research Centre of Finland, Tietotie 2, Espoo, P, O, Box 1000, 02044 VTT Espoo, Finland
    BMC Genomics 7:247. 2006
    ..Transcriptional responses caused by transient oxygen deprivations and production of foreign protein were also studied in T. reesei by TRAC...
  6. ncbi request reprint Central carbon metabolism of Saccharomyces cerevisiae in anaerobic, oxygen-limited and fully aerobic steady-state conditions and following a shift to anaerobic conditions
    Marilyn G Wiebe
    VTT Technical Research Centre of Finland, Finland
    FEMS Yeast Res 8:140-54. 2008
    ..Gene regulation was more complex, with some genes showing transient upregulation or downregulation during the adaptation to anaerobic conditions...
  7. pmc Low oxygen levels as a trigger for enhancement of respiratory metabolism in Saccharomyces cerevisiae
    Eija Rintala
    VTT Technical Research Centre of Finland, P, O, Box 1000, FI 02044 VTT, Finland
    BMC Genomics 10:461. 2009
    ..cerevisiae in glucose-limited chemostat cultivations in anaerobic and aerobic conditions, and with three intermediate (0.5, 1.0 and 2.8% oxygen) levels of oxygen in the feed gas...
  8. pmc Engineering filamentous fungi for conversion of D-galacturonic acid to L-galactonic acid
    Joosu Kuivanen
    VTT Technical Research Centre of Finland, Espoo, Finland
    Appl Environ Microbiol 78:8676-83. 2012
    ..niger also delayed or prevented induction of the putative d-galacturonate transporter An14g04280. In addition, A. niger ΔgaaB produced l-galactonate from polygalacturonate as efficiently as from the monomer...
  9. pmc Transcription of hexose transporters of Saccharomyces cerevisiae is affected by change in oxygen provision
    Eija Rintala
    VTT, Technical Research Centre of Finland, PO Box 1000, FI 02044 VTT, Finland
    BMC Microbiol 8:53. 2008
    ..5, 1, 2.8 and 20.9% O2), and from cells under conditions in which oxygen was introduced to anaerobic cultures or removed from cultures receiving oxygen...
  10. pmc Transcriptional responses of Saccharomyces cerevisiae to shift from respiratory and respirofermentative to fully fermentative metabolism
    Eija Rintala
    VTT Technical Research Centre of Finland, Finland
    OMICS 15:461-76. 2011
    ....
  11. doi request reprint Metabolic engineering of Saccharomyces cerevisiae for bioconversion of D-xylose to D-xylonate
    Mervi Toivari
    VTT, Technical Research Centre of Finland, PO Box 1000, FI 02044 VTT, Espoo, Finland
    Metab Eng 14:427-36. 2012
    ..Cell vitality and viability decreased during D-xylonate production at pH 3.0. An industrial S. cerevisiae strain expressing xylB efficiently produced 43 g D-xylonate l(-1) from 49 g D-xylose l(-1)...
  12. doi request reprint Low pH D-xylonate production with Pichia kudriavzevii
    Mervi Toivari
    VTT, Technical Research Centre of Finland, VTT, Espoo, Finland
    Bioresour Technol 133:555-62. 2013
    ..2 g L(-1) h(-1) at pH 3.0. This is the best low pH production reported for D-xylonate. These results encourage further development towards industrial scale production...
  13. doi request reprint Saccharomyces cerevisiae engineered to produce D-xylonate
    Mervi H Toivari
    VTT, Technical Research Centre of Finland, P O Box 1000, FI 02044 VTT Espoo, Finland
    Appl Microbiol Biotechnol 88:751-60. 2010
    ..Although each of these enzymes enhanced NADPH consumption on D-glucose, they did not enhance D-xylonate production, suggesting that NADP+ was not the main limitation in the current D-xylonate producing strains...
  14. pmc Microbial D-xylonate production
    Mervi H Toivari
    VTT, Technical Research Centre of Finland, P O Box 1000, 02044 VTT Espoo, Finland
    Appl Microbiol Biotechnol 96:1-8. 2012
    ..oxydans, at a volumetric rate approximately 30% of that observed with G. oxydans. With further development, genetically modified microbes may soon provide an alternative for production of D-xylonate at industrial scale...
  15. doi request reprint Mixotrophic continuous flow cultivation of Chlorella protothecoides for lipids
    Yanming Wang
    VTT Technical Research Centre of Finland, P O Box 1000, FI 02044 VTT, Espoo, Finland
    Bioresour Technol 144:608-14. 2013
    ....
  16. ncbi request reprint Production of Fusarium solani f. sp. pisi cutinase in Fusarium venenatum A3/5
    Jacob Dam Sørensen
    Department of Biotechnology, Chemistry and Environmental Engineering, Aalborg University, Sohngaardsholmsvej 49, Aalborg, 9000, Denmark
    Biotechnol Lett 29:1227-32. 2007
    ..Glucoamylase (165 U l(-1) or 8 mg l(-1)) was also produced. Both the transformant and the parent strain produced cutinase in medium containing cutin...
  17. ncbi request reprint Acid phosphatase production by Aspergillus niger N402A in continuous flow culture
    Budi J Hidayat
    Department of Life Sciences, Aalborg University, Aalborg, Denmark
    FEMS Microbiol Lett 254:324-31. 2006
    ..Four different ACPs, including two phytases, were produced by A. niger N402A. The ACP and the phytase with maximal activities at pH 5.5 were differentially expressed at different culture pH values, with greater production at low pH...
  18. ncbi request reprint Rhodotorulic acid production by Rhodotorula mucilaginosa
    Ditte Andersen
    Department of Life Sciences, Sohngaardsholmsvej 49, Aalborg University, DK 9000 Aalborg, Denmark
    Mycol Res 107:949-56. 2003
    ..Citric acid was an effective suppresser of RA production. RA was produced in a growth rate dependent manner and was optimally produced at pH 6.5...
  19. pmc Development and application of an assay for uranyl complexation by fungal metabolites, including siderophores
    Joanna C Renshaw
    Centre for Radiochemistry Research, Department of Chemistry, The University of Manchester, Manchester M13 9PT, United Kingdom
    Appl Environ Microbiol 69:3600-6. 2003
    ..Our results show that the new assay can be effectively used to screen fungi for the production of UO(2)(2+) chelating ligands. We suggest that hydroxamate siderophores can be produced by mucoraceous fungi...