Research Topics
| K WahlbeckSummaryAffiliation: University of Helsinki Country: Finland Publications
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Detail Information
Publications
Risperidone versus clozapine in treatment-resistant schizophrenia: a randomized pilot studyK Wahlbeck
Department of Psychiatry, University of Helsinki, Finland
Prog Neuropsychopharmacol Biol Psychiatry 24:911-22. 2000....
Evidence of clozapine's effectiveness in schizophrenia: a systematic review and meta-analysis of randomized trialsK Wahlbeck
Department of Psychiatry, University of Helsinki, Finland
Am J Psychiatry 156:990-9. 1999..The purpose of this study was to evaluate all available trial-based evidence on the effectiveness of clozapine in schizophrenia as compared with conventional neuroleptics...
Current antipsychotic dose correlates to mononuclear cell counts in the cerebrospinal fluid of psychotic patientsK Wahlbeck
Department of Psychiatry, University of Helsinki, PB 320, FIN 00029, HUCH, Finland
Psychiatry Res 93:13-9. 2000..This finding needs replication and further corroboration in well-designed studies...
Association of schizophrenia with low maternal body mass index, small size at birth, and thinness during childhoodK Wahlbeck
Department of Psychiatry, University of Helsinki, Lappviksvägen, PO Box 320, FIN 00029, Helsinki, Finland
Arch Gen Psychiatry 58:48-52. 2001..Nutritional factors in early life may contribute to the neurodevelopmental deficit in schizophrenia. This study explores the influence of maternal body size, size at birth, and childhood growth on future risk for schizophrenia...
Efficacy of beta-blocker supplementation for schizophrenia: a systematic review of randomized trialsK Wahlbeck
Department of Psychiatry, University of Helsinki, Lappviksvägen, Finland
Schizophr Res 41:341-7. 2000..At present beta-blockers cannot be recommended in the treatment of schizophrenia, and schizophrenia treatment guidelines advocating use of beta-blockers should be revised...
Influence of methodology on outcomes of randomised clozapine trialsK Wahlbeck
Department of Psychiatry, University of Helsinki, Finland
Pharmacopsychiatry 33:54-9. 2000..No other quality items correlated to the primary outcomes. Inadequate randomisation techniques may be a source of bias in clozapine studies, but much more research is needed on the connections between trial quality and trial outcome...
A longitudinal study of cerebrospinal fluid angiotensin-converting enzyme in neuroleptic-treated schizophreniaK Wahlbeck
Department of Psychiatry, University of Helsinki, Finland
Prog Neuropsychopharmacol Biol Psychiatry 21:591-9. 1997....
Cerebrospinal fluid angiotensin-converting enzyme (ACE) correlates with length of illness in schizophreniaK Wahlbeck
Department of Psychiatry, University of Helsinki, Lappviksvägen, Finland
Schizophr Res 41:335-40. 2000..This may be a function of treatment or a result of the deteriorating schizophrenic process...
Associations between childhood living circumstances and schizophrenia: a population-based cohort studyK Wahlbeck
Department of Psychiatry, University of Helsinki, , PO Box 320, FIN-00029 HUCH Helsinki, Finland
Acta Psychiatr Scand 104:356-60. 2001..Other possible underlying mechanisms of the associations found include infectious and psychological factors...
Dropout rates in randomised antipsychotic drug trialsK Wahlbeck
Department of Psychiatry, University of Helsinki, HUS, Finland
Psychopharmacology (Berl) 155:230-3. 2001..It has been assumed that new atypical drugs improve treatment compliance due to fewer adverse effects. Data supporting this assumption are scarce...
Estrogen deficiency in severe postpartum depression: successful treatment with sublingual physiologic 17beta-estradiol: a preliminary studyA Ahokas
Psychiatric Research Unit, Mehilainen Clinic, University of Helsinki, Finland
J Clin Psychiatry 62:332-6. 2001..To evaluate the association between estradiol and postpartum depression, we measured serum estradiol concentration and performed an open-label study of physiologic 17beta-estradiol...
Decrease of energy expenditure causes weight increase in olanzapine treatment - a case studyM Virkkunen
Department of Psychiatry, University of Helsinki, Finland
Pharmacopsychiatry 35:124-6. 2002..Insulin sensitivity did not change. We conclude that decreased basal energy expenditure may contribute to weight gain in olanzapine treatment...
Actometry in measuring the symptom severity of restless legs syndromeK Tuisku
Department of Psychiatry, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland
Eur J Neurol 12:385-7. 2005..Both our standardized actometric parameters (nocturnal lower limb activity and controlled rest activity) decreased significantly during the intervention in parallel with the subjectively reported relief of RLS symptoms...
