Erkki Vuori

Summary

Affiliation: University of Helsinki
Country: Finland

Publications

  1. ncbi request reprint Abuse liability of buprenorphine-naloxone tablets in untreated IV drug users
    Hannu Alho
    National Public Health Institute, Department of Mental Health and Alcohol Research, Helsinki, Finland
    Drug Alcohol Depend 88:75-8. 2007
  2. ncbi request reprint Wastewater analysis reveals regional variability in exposure to abused drugs and opioids in Finland
    Erkki Vuori
    Hjelt Institute, Department of Forensic Medicine, University of Helsinki, P O Box 40, 00014 University of Helsinki, Helsinki, Finland Electronic address
    Sci Total Environ 487:688-95. 2014
  3. ncbi request reprint Death following ingestion of MDMA (ecstasy) and moclobemide
    Erkki Vuori
    Department of Forensic Medicine, University of Helsinki, Finland
    Addiction 98:365-8. 2003
  4. ncbi request reprint Comparison of fatal poisonings by prescription opioids
    Margareeta Häkkinen
    University of Helsinki, Hjelt Institute, Department of Forensic Medicine, PO Box 40 Kytösuontie 11, FI 00014 Helsinki, Finland
    Forensic Sci Int 222:327-31. 2012
  5. ncbi request reprint Adverse interaction of warfarin and paracetamol: evidence from a post-mortem study
    Terhi Launiainen
    Department of Forensic Medicine, University of Helsinki, Helsinki, Finland
    Eur J Clin Pharmacol 66:97-103. 2010
  6. ncbi request reprint Quantification of drugs in plasma without primary reference standards by liquid chromatography-chemiluminescence nitrogen detection: application to tramadol metabolite ratios
    Suvi Ojanperä
    Department of Forensic Medicine, University of Helsinki, Helsinki, Finland
    Ther Drug Monit 29:423-8. 2007
  7. ncbi request reprint CYP2D6 and CYP2C19 genotypes and amitriptyline metabolite ratios in a series of medicolegal autopsies
    Anna Koski
    Laboratory of Toxicology, Department of Forensic Medicine, P O Box 40, FI 00014 University of Helsinki, Finland
    Forensic Sci Int 158:177-83. 2006
  8. doi request reprint Benzodiazepines and alcohol are associated with cases of fatal buprenorphine poisoning
    Margareeta Häkkinen
    Department of Forensic Medicine, University of Helsinki, Hjelt Institute, PO Box 40, Kytosuontie 11, Helsinki, 00014, Finland
    Eur J Clin Pharmacol 68:301-9. 2012
  9. doi request reprint Fatal venlafaxine poisonings are associated with a high prevalence of drug interactions
    Terhi Launiainen
    Department of Forensic Medicine, University of Helsinki, P O Box 40, FI 00014, Helsinki, Finland
    Int J Legal Med 125:349-58. 2011
  10. ncbi request reprint An epidemic of fatal 3-methylfentanyl poisoning in Estonia
    Ilkka Ojanpera
    Department of Forensic Medicine, University of Helsinki, P O Box 40, 00014, Helsinki, Finland
    Int J Legal Med 122:395-400. 2008

Collaborators

Detail Information

Publications30

  1. ncbi request reprint Abuse liability of buprenorphine-naloxone tablets in untreated IV drug users
    Hannu Alho
    National Public Health Institute, Department of Mental Health and Alcohol Research, Helsinki, Finland
    Drug Alcohol Depend 88:75-8. 2007
    ..Its street price was less than half that of buprenorphine alone. The buprenorphine+naloxone combination appears to be a feasible tool, along with easier access to addiction treatment, for decreasing IV abuse of buprenorphine...
  2. ncbi request reprint Wastewater analysis reveals regional variability in exposure to abused drugs and opioids in Finland
    Erkki Vuori
    Hjelt Institute, Department of Forensic Medicine, University of Helsinki, P O Box 40, 00014 University of Helsinki, Helsinki, Finland Electronic address
    Sci Total Environ 487:688-95. 2014
    ..Although the method has limitations, wastewater analysis gives additional information for assessing the degree of drug abuse and range of drugs abused in a society...
  3. ncbi request reprint Death following ingestion of MDMA (ecstasy) and moclobemide
    Erkki Vuori
    Department of Forensic Medicine, University of Helsinki, Finland
    Addiction 98:365-8. 2003
    ..Warnings are needed against misinformed attempts to potentiate the pharmacological effects of illicit drugs...
  4. ncbi request reprint Comparison of fatal poisonings by prescription opioids
    Margareeta Häkkinen
    University of Helsinki, Hjelt Institute, Department of Forensic Medicine, PO Box 40 Kytösuontie 11, FI 00014 Helsinki, Finland
    Forensic Sci Int 222:327-31. 2012
    ..35 mg/l) was not different from that in other causes of death (0.30 mg/l). Sedative drugs and/or alcohol were very frequently found in fatal poisonings involving these prescription opioids...
  5. ncbi request reprint Adverse interaction of warfarin and paracetamol: evidence from a post-mortem study
    Terhi Launiainen
    Department of Forensic Medicine, University of Helsinki, Helsinki, Finland
    Eur J Clin Pharmacol 66:97-103. 2010
    ..Another purpose was to obtain facts related to the questioned safety of warfarin-paracetamol and warfarin-tramadol combinations...
  6. ncbi request reprint Quantification of drugs in plasma without primary reference standards by liquid chromatography-chemiluminescence nitrogen detection: application to tramadol metabolite ratios
    Suvi Ojanperä
    Department of Forensic Medicine, University of Helsinki, Helsinki, Finland
    Ther Drug Monit 29:423-8. 2007
    ..This experiment suggests that a recovery-corrected LC-CLND analysis produces sufficiently accurate results to be useful in a clinical context, particularly in instances in which reference standards are not readily accessible...
  7. ncbi request reprint CYP2D6 and CYP2C19 genotypes and amitriptyline metabolite ratios in a series of medicolegal autopsies
    Anna Koski
    Laboratory of Toxicology, Department of Forensic Medicine, P O Box 40, FI 00014 University of Helsinki, Finland
    Forensic Sci Int 158:177-83. 2006
    ..This result demonstrates the feasibility of postmortem pharmacogenetic analysis and supports the dominant role of genes in drug metabolism...
  8. doi request reprint Benzodiazepines and alcohol are associated with cases of fatal buprenorphine poisoning
    Margareeta Häkkinen
    Department of Forensic Medicine, University of Helsinki, Hjelt Institute, PO Box 40, Kytosuontie 11, Helsinki, 00014, Finland
    Eur J Clin Pharmacol 68:301-9. 2012
    ..In Finland, buprenorphine is the most important abused opioid causing fatal poisonings...
  9. doi request reprint Fatal venlafaxine poisonings are associated with a high prevalence of drug interactions
    Terhi Launiainen
    Department of Forensic Medicine, University of Helsinki, P O Box 40, FI 00014, Helsinki, Finland
    Int J Legal Med 125:349-58. 2011
    ..In conclusion, the high suicide potential of VEN in combination with the high prevalence of drugs causing adverse interactions could be the reason for the observed high FTI...
  10. ncbi request reprint An epidemic of fatal 3-methylfentanyl poisoning in Estonia
    Ilkka Ojanpera
    Department of Forensic Medicine, University of Helsinki, P O Box 40, 00014, Helsinki, Finland
    Int J Legal Med 122:395-400. 2008
    ..9 microg/l) was more than ten times lower than the mean fentanyl concentration in fentanyl-related fatalities. Concomitant use of other drugs involved alcohol, amphetamines, benzodiazepines, and cannabis, but very rarely other opioids...
  11. ncbi request reprint A fatal doxepin poisoning associated with a defective CYP2D6 genotype
    Anna Koski
    Department of Forensic Medicine, University of Helsinki, Helsinki, Finland
    Am J Forensic Med Pathol 28:259-61. 2007
    ..Our case strongly emphasizes that a pharmacogenetic analysis in postmortem forensic setting may reveal new insight to the cause or manner of death...
  12. ncbi request reprint Application of accurate mass measurement to urine drug screening
    Lkka Ojanperä
    Department of Forensic Medicine, University of Helsinki, P O Box 40, FIN 00014, Helsinki, Finland
    J Anal Toxicol 29:34-40. 2005
    ..In contrast to ordinary techniques requiring primary reference standards, the formula-based databases can be updated instantly with fresh numeric data from scientific literature and authority sources...
  13. ncbi request reprint A rare case of serial killing by poisoning
    Erkki Vuori
    Hjelt Institute, Department of Forensic Medicine, University of Helsinki, Finland
    Drug Test Anal 5:725-9. 2013
    ..The nurse was eventually found guilty of five murders by poisoning, five attempted murders, and three aggravated assaults. The nurse was sentenced to life imprisonment...
  14. doi request reprint Elevated formic acid concentrations in putrefied post-mortem blood and urine samples
    Jenni Viinamäki
    Hjelt Institute, Department of Forensic Medicine, University of Helsinki, Helsinki, Finland
    Forensic Sci Int 208:42-6. 2011
    ..Poor correlation was shown between blood and urine concentrations of FA. Poor correlations were also shown, in both blood and urine, between methanol and FA concentrations...
  15. ncbi request reprint Blood levels of 3-methylfentanyl in 3 fatal poisoning cases
    Ilkka Ojanpera
    Department of Forensic Medicine, University of Helsinki, Helsinki, Finland
    Am J Forensic Med Pathol 27:328-31. 2006
    ..5 microg/L). These values are significantly lower than the levels reported for alpha-methylfentanyl and fentanyl in fatal poisonings. Repeated seizures of fentanyl and its analogs have been reported in Europe close to the Russian border...
  16. ncbi request reprint Newer antidepressants: evaluation of fatal toxicity index and interaction with alcohol based on Finnish postmortem data
    Anna Koski
    Laboratory of Toxicology, Department of Forensic Medicine, P O Box 40, 00014 University of Helsinki, Finland
    Int J Legal Med 119:344-8. 2005
    ..The SSRIs appear to present a low risk of fatal poisoning when taken alone or in combination with alcohol, whereas venlafaxine is associated with an elevated risk...
  17. ncbi request reprint Screening for basic drugs in hair of drug addicts by liquid chromatography/time-of-flight mass spectrometry
    Anna Pelander
    Department of Forensic Medicine, University of Helsinki, Helsinki, Finland
    Ther Drug Monit 30:717-24. 2008
    ..5 and 0.4 mDa, respectively. Cutoff values for tramadol and methamphetamine in hair were 100 and 200 pg/mg, respectively. The method proved to be a simple and straightforward tool for comprehensive screening of basic drugs in hair...
  18. doi request reprint Under-recording of ethanol intoxication and poisoning in cause-of-death data: causes and consequences
    Raimo A Lahti
    Hjelt Institute, Department of Forensic Medicine, 00014 University of Helsinki, Finland
    Forensic Sci Int 212:121-5. 2011
    ....
  19. doi request reprint Prevalence of adverse drug combinations in a large post-mortem toxicology database
    Terhi Launiainen
    Department of Forensic Medicine, University of Helsinki, P O Box 40, 00014, Helsinki, Finland
    Int J Legal Med 123:109-15. 2009
    ..In one third of the possible ADI cases, a forensic pathologist had noted the studied compounds as an underlying or contributing cause of death, although the agents' specific role in ADIs was rarely recognised...
  20. ncbi request reprint Isotopic pattern and accurate mass determination in urine drug screening by liquid chromatography/time-of-flight mass spectrometry
    Suvi Ojanperä
    Department of Forensic Medicine, University of Helsinki, Helsinki, Finland
    Rapid Commun Mass Spectrom 20:1161-7. 2006
    ..The results show that isotopic pattern matching by SigmaFit is a powerful means of identification in addition to accurate mass measurement...
  21. pmc Infant botulism acquired from household dust presenting as sudden infant death syndrome
    Mari Nevas
    Department of Food and Environmental Hygiene, Faculty of Veterinary Medicine, University of Helsinki, P O Box 66, 00014 Helsinki University, Finland
    J Clin Microbiol 43:511-3. 2005
    ....
  22. ncbi request reprint Profiles of pregabalin and gabapentin abuse by postmortem toxicology
    Margareeta Häkkinen
    Hjelt Institute, Department of Forensic Medicine, University of Helsinki, Kytosuontie 11, P O Box 40, Helsinki FI 00014, Finland Electronic address
    Forensic Sci Int 241:1-6. 2014
    ..In the GBP abuser group, 87.5% of cases showed concomitant opioid use. PRG abuse with high doses is increasingly common and can be fatal when combined with opioids. ..
  23. ncbi request reprint Analysis of street drugs in seized material without primary reference standards
    Suvi Laks
    Department of Forensic Medicine, University of Helsinki, P O Box 40, FIN 00014 Helsinki, Finland
    Anal Chem 76:7375-9. 2004
    ..Results suggest that the present combination of LC/TOFMS and LC/CLND offers a simple solution for the analysis of scheduled and designer drugs in seized material, independent of the availability of primary reference standards...
  24. ncbi request reprint Headspace in-tube extraction gas chromatography-mass spectrometry for the analysis of hydroxylic methyl-derivatized and volatile organic compounds in blood and urine
    Ilpo Rasanen
    Department of Forensic Medicine, Kytosuontie 11, University of Helsinki, Finland
    J Anal Toxicol 34:113-21. 2010
    ..The ITEX method described here was more sensitive for analysis of volatile organic compounds than the corresponding static headspace analysis as demonstrated for 11 representative compounds...
  25. ncbi request reprint Post-mortem SNP analysis of CYP2D6 gene reveals correlation between genotype and opioid drug (tramadol) metabolite ratios in blood
    Antti Levo
    Laboratory of Forensic Biology, Department of Forensic Medicine, P O Box 40, 00014, University of Helsinki, Finland
    Forensic Sci Int 135:9-15. 2003
    ..The results also suggest that genetic factors play, in general, a dominant role over other factors in the metabolism of individual drugs...
  26. ncbi request reprint Alcohol tax cuts and increase in alcohol-positive sudden deaths: a time-series intervention analysis
    Anna Koski
    Department of Forensic Medicine, University of Helsinki, Finland
    Addiction 102:362-8. 2007
    ....
  27. ncbi request reprint Interaction of alcohol and drugs in fatal poisonings
    Anna Koski
    Laboratory of Toxicology, Department of Forensic Medicine, FIN 00014, University of Helsinki, Finland
    Hum Exp Toxicol 22:281-7. 2003
    ..The other drugs had relatively low FTIs. The results reflect not only the acute toxicity of a given drug-alcohol combination but also the manners of use and abuse of these drugs...
  28. ncbi request reprint Performance of immunoassays in screening for opiates, cannabinoids and amphetamines in post-mortem blood
    Yukiko Hino
    Department of Forensic Medicine, University of Helsinki, PO Box 40, FIN 00014, Helsinki, Finland
    Forensic Sci Int 131:148-55. 2003
    ..The modified EMIT immunoassay system presented here seems to be useful for screening of drugs of abuse in post-mortem blood samples, especially when urine is not available...
  29. ncbi request reprint Second-generation antihistamines exhibit a protective effect on drivers in traffic-a preliminary population-based case-control study
    Antti Perttula
    a Division of Forensic Toxicology, Hjelt Institute, University of Helsinki, University of Helsinki, Helsinki, Finland
    Traffic Inj Prev 15:551-5. 2014
    ..This is the first population-based epidemiological study concerning the association of sedating/nonsedating antihistamines and fatal traffic accidents...
  30. ncbi request reprint Screening for basic drugs in 2-mL urine samples by dual-plate overpressured layer chromatography and comparison with gas chromatography-mass spectrometry
    Anna Pelander
    Department of Forensic Medicine, PO Box 40, FIN 00014 University of Helsinki, Finland
    J Anal Toxicol 27:226-32. 2003
    ..The OPLC method thus provides an alternative for current planar and column liquid chromatographic drug screening methods with the possibility of lowering detection limits by using a larger sample size...