R Trokovic

Summary

Affiliation: University of Helsinki
Country: Finland

Publications

  1. doi request reprint Generation of iPSC line HEL24.3 from human neonatal foreskin fibroblasts
    Ras Trokovic
    Research Programs Unit, Molecular Neurology, Biomedicum Stem Cell Centre, University of Helsinki, Helsinki, Finland Electronic address
    Stem Cell Res 15:266-8. 2015
  2. doi request reprint Generation of iPSC line HEL47.2 from healthy human adult fibroblasts
    Ras Trokovic
    Research Programs Unit, Molecular Neurology, Biomedicum Stem Cell Centre, University of Helsinki, Helsinki, Finland Electronic address
    Stem Cell Res 15:263-5. 2015
  3. doi request reprint Combined negative effect of donor age and time in culture on the reprogramming efficiency into induced pluripotent stem cells
    Ras Trokovic
    Research Programs Unit, Molecular Neurology, Biomedicum Stem Cell Center, University of Helsinki, Helsinki, Finland Electronic address
    Stem Cell Res 15:254-62. 2015
  4. doi request reprint Small molecule inhibitors promote efficient generation of induced pluripotent stem cells from human skeletal myoblasts
    Ras Trokovic
    Research Programs Unit, Molecular Neurology, Biomedicum Stem Cell Center, University of Helsinki, Helsinki, Finland
    Stem Cells Dev 22:114-23. 2013
  5. pmc Induced pluripotent stem cell clones reprogrammed via recombinant adeno-associated virus-mediated transduction contain integrated vector sequences
    J Weltner
    Research Programs Unit, Molecular Neurology, Biomedicum Stem Cell Centre, University of Helsinki, Helsinki, Finland
    J Virol 86:4463-7. 2012

Collaborators

Detail Information

Publications5

  1. doi request reprint Generation of iPSC line HEL24.3 from human neonatal foreskin fibroblasts
    Ras Trokovic
    Research Programs Unit, Molecular Neurology, Biomedicum Stem Cell Centre, University of Helsinki, Helsinki, Finland Electronic address
    Stem Cell Res 15:266-8. 2015
    ..Human iPSC line HEL24.3 was generated from healthy human foreskin fibroblasts using non-integrative reprogramming method. Reprogramming factors Oct3/4, Sox2, Klf4, and cMyc were delivered using Sendai viruses. ..
  2. doi request reprint Generation of iPSC line HEL47.2 from healthy human adult fibroblasts
    Ras Trokovic
    Research Programs Unit, Molecular Neurology, Biomedicum Stem Cell Centre, University of Helsinki, Helsinki, Finland Electronic address
    Stem Cell Res 15:263-5. 2015
    ..Human iPSC line HEL47.2 was generated from healthy 83-year old male dermal fibroblasts using non-integrative reprogramming method. Reprogramming factors Oct3/4, Sox2, Klf4, and cMyc were delivered using Sendai viruses. ..
  3. doi request reprint Combined negative effect of donor age and time in culture on the reprogramming efficiency into induced pluripotent stem cells
    Ras Trokovic
    Research Programs Unit, Molecular Neurology, Biomedicum Stem Cell Center, University of Helsinki, Helsinki, Finland Electronic address
    Stem Cell Res 15:254-62. 2015
    ..Knockdown of p21 restored iPSC generation even in long-term passaged fibroblasts of an old donor, highlighting the central role of the p53/p21 pathway in cellular senescence induced by both donor age and culture time. ..
  4. doi request reprint Small molecule inhibitors promote efficient generation of induced pluripotent stem cells from human skeletal myoblasts
    Ras Trokovic
    Research Programs Unit, Molecular Neurology, Biomedicum Stem Cell Center, University of Helsinki, Helsinki, Finland
    Stem Cells Dev 22:114-23. 2013
    ....
  5. pmc Induced pluripotent stem cell clones reprogrammed via recombinant adeno-associated virus-mediated transduction contain integrated vector sequences
    J Weltner
    Research Programs Unit, Molecular Neurology, Biomedicum Stem Cell Centre, University of Helsinki, Helsinki, Finland
    J Virol 86:4463-7. 2012
    ..It thus appears that rAAV vectors are not compatible with the derivation of integration-free iPSC...