Research Topics
Species | Timo E StrandbergSummaryAffiliation: University of Oulu Country: Finland Publications
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Detail Information
Publications
Explaining the obesity paradox: cardiovascular risk, weight change, and mortality during long-term follow-up in menTimo E Strandberg
Institute of Health Sciences Geriatrics, University of Oulu and University Hospital, Unit of General Practice, FIN 90014 Oulu, Finland
Eur Heart J 30:1720-7. 2009..To examine life-long weight trajectories behind the 'obesity paradox', and whether cardiovascular disease (CVD) risk contributes...
Association between alcohol consumption in healthy midlife and telomere length in older men. The Helsinki Businessmen StudyTimo E Strandberg
Unit of General Practice, Institute of Health Sciences Geriatrics, University of Oulu Oulun Yliopisto and University Hospital, Oulu, Finland
Eur J Epidemiol 27:815-22. 2012..Even minor alcohol consumption in midlife was significantly associated with shorter telomere length in old age. The differences represent an up to 10 year gap in biological age between zero and highest consumption...
Association of midlife obesity and cardiovascular risk with old age frailty: a 26-year follow-up of initially healthy menT E Strandberg
Institute of Health Sciences Geriatrics, University of Oulu and Oulu University Hospital, Unit of General Practice, Oulu, Finland
Int J Obes (Lond) 36:1153-7. 2012..To investigate whether old age frailty is predicted by midlife overweight/obesity and cardiovascular disease (CVD) risk...
Cholesterol and glucose metabolism and recurrent cardiovascular events among the elderly: a prospective studyTimo E Strandberg
Department of Public Health Science and General Practice, University of Oulu, Oulu, Finland
J Am Coll Cardiol 48:708-14. 2006....
Comparative effect of atorvastatin (80 mg) versus simvastatin (20 to 40 mg) in preventing hospitalizations for heart failure in patients with previous myocardial infarctionTimo E Strandberg
Department of Health Sciences Geriatrics, University of Oulu, and Oulu University Hospital, Unit of General Practice, Oulu, Finland
Am J Cardiol 103:1381-5. 2009..73, 95% CI 0.54 to 0.97, p = 0.03). In conclusion, atorvastatin 80 mg was more efficient than simvastatin 20 to 40 mg in preventing development of HF in patients with previous MI...
Frailty in elderly peopleTimo E Strandberg
University of Oulu, Oulu, FIN-90014, Finland
Lancet 369:1328-9. 2007
Alcoholic beverage preference, 29-year mortality, and quality of life in men in old ageTimo E Strandberg
Department of Public Health Science and General Practice, University of Oulu, Finland
J Gerontol A Biol Sci Med Sci 62:213-8. 2007..We compared 29-year mortality and quality of life in old age by alcoholic beverage preference (beer, wine, or spirits) in a cohort of men whose socioeconomic status was similar in their adult life...
Chocolate, well-being and health among elderly menT E Strandberg
Unit of General Practice, Department of Public Health Science and General Practice, University of Oulu and Oulu University Hospital, Oulu, Finland
Eur J Clin Nutr 62:247-53. 2008..We hypothesized that chocolate preference would be related to health and psychological well-being in old men...
Cardiovascular risk in midlife and psychological well-being among older menTimo E Strandberg
Department of Public Health Science and General Practice, University of Oulu, Oulu, Finland
Arch Intern Med 166:2266-71. 2006..We investigated whether cardiovascular disease risk in midlife is related to psychological well-being in older men (aged 69-84 years old)...
Multifactorial intervention to prevent recurrent cardiovascular events in patients 75 years or older: the Drugs and Evidence-Based Medicine in the Elderly (DEBATE) study: a randomized, controlled trialTimo E Strandberg
Department of Public Health Science and General Practice, University of Oulu, University Hospital, Oulu, Finland
Am Heart J 152:585-92. 2006..We aimed to examine whether better use of preventive methods and treatments of cardiovascular disease would reduce recurrent events in home-dwelling patients 75 years or older...
Biogerontology in FinlandTimo E Strandberg
Institute of Health Sciences Geriatrics, Oulu University Hospital, University of Oulu, Oulu, Finland
Biogerontology 12:71-5. 2011..The research activity of each institute and their international collaboration is briefly described with examples focused on recent publications in the field of biogerontology...
Serum plant and other noncholesterol sterols, cholesterol metabolism and 22-year mortality among middle-aged menTimo E Strandberg
Institute of Health Sciences Geriatrics, University of Oulu, and Oulu University Hospital, Unit of General Practice, PO Box 5000, FIN 90014, Oulu, Finland
Atherosclerosis 210:282-7. 2010..To evaluate long-term prognostic effect of serum noncholesterol sterols, including plant sterols, in middle-aged men with high cardiovascular disease (CVD) risk, without statins at baseline...
Lipid-lowering drugs and heart failure: where do we go after the statin trials?Timo E Strandberg
Institute of Health Sciences Geriatrics, University of Oulu, Oulu University Hospital, Oulu, Finland
Curr Opin Cardiol 25:385-93. 2010..The role of other types of dyslipidemia [low high-density lipoprotein (HDL), high triglycerides] and their modification has received less attention in heart failure thus far...
Definition of frailty in older men according to questionnaire data (RAND-36/SF-36): The Helsinki Businessmen StudyJ Sirola
Helsinki University Hospital, Unit of General Practice, Helsinki, Finland
J Nutr Health Aging 15:783-7. 2011..To explore the association of frailty according to questionnaire data (modified Fried criteria) with important endpoints in older men...
Predictors of mortality in home-dwelling patients with cardiovascular disease aged 75 and olderTimo E Strandberg
Department of Health Sciences Geriatrics, University of Oulu, Oulu University Hospital, Finland
J Am Geriatr Soc 57:279-84. 2009..To compare the predictive value of biomarkers commonly measured in older patients with cardiovascular disease (CVD) with an indicator of cognitive function...
Association of telomere length in older men with mortality and midlife body mass index and smokingTimo E Strandberg
Unit of General Practice, Institute of Health Sciences Geriatrics, University of Oulu and University Hospital, Finland
J Gerontol A Biol Sci Med Sci 66:815-20. 2011..Leukocyte telomere length has been taken as a measure of biological age but several inconsistencies exist...
Exercise rehabilitation on home-dwelling patients with Alzheimer's disease--a randomized, controlled trial. Study protocolKaisu H Pitkala
Unit of General Practice, Helsinki University Central Hospital, University of Helsinki, PO Box 20, 00014 University of Helsinki, Finland
Trials 11:92. 2010..The aim of this study is to investigate the effectiveness of intensive exercise rehabilitation lasting for one year on mobility and physical functioning of home-dwelling patients with AD...
Will-to-live and survival in a 10-year follow-up among older peopleHelena Karppinen
Unit of General Practice, Helsinki University Central Hospital, Helsinki, Finland
Age Ageing 41:789-94. 2012..there is little research how older people's will-to-live predicts their survival...
Association between anticholinergic drugs and apolipoprotein E epsilon4 allele and poorer cognitive function in older cardiovascular patients: a cross-sectional studyJuho Uusvaara
Unit of General Practice, Helsinki University Hospital, Helsinki, Finland
J Am Geriatr Soc 57:427-31. 2009..To clarify the association between anticholinergic drugs and apolipoprotein E epsilon4 allele carrier status (APOE4) and cognitive dysfunction...
The overlap of delirium with neuropsychiatric symptoms among patients with dementiaEeva Hölttä
Unit of General Practice, Helsinki University Central Hospital and University of Helsinki, Finland
Am J Geriatr Psychiatry 19:1034-41. 2011..To study the frequency of overlapping of delirium with neuropsychiatric symptoms (NPS) among patients with dementia, and to investigate the prognostic value of delirium, multiple NPS without delirium, or neither during a 2-year follow-up...
Inflammation markers and malnutrition as risk factors for infections and impaired health-related quality of life among older nursing home residentsLiisa K Kuikka
University of Helsinki, Department of General Practice and Helsinki University Hospital, Unit of General Practice, Mannerheimintie 172 PL 41, Helsinki, Finland
J Am Med Dir Assoc 10:348-53. 2009..To explore malnutrition and inflammation markers as risk factors for poor outcome such as infections and impaired health-related quality-of-life (HRQoL) among nursing home residents...
Multicomponent geriatric intervention for elderly inpatients with delirium: effects on costs and health-related quality of lifeKaisu H Pitkala
Unit of General Practice, University of Helsinki, Finland
J Gerontol A Biol Sci Med Sci 63:56-61. 2008..We studied the effects of multicomponent geriatric treatment on costs of care and HRQoL in delirious inpatients...
Interest in healthy lifestyle and adherence to medications: Impact on mortality among elderly cardiovascular patients in the DEBATE StudyKaisu H Pitkala
University of Helsinki, Department of Primary Care and General Practice, Helsinki, Finland
Patient Educ Couns 67:44-9. 2007..We examined how a patient-centered consultation can help the physician to evaluate older patients' adherence to medical care and a healthy lifestyle. We hypothesised that an accurate estimate of adherence should be shown in their prognosis...
The effect of smoking in midlife on health-related quality of life in old age: a 26-year prospective studyArto Y Strandberg
Department of Medicine, Geriatric Clinic, University of Helsinki, PL 340, 00029 Helsinki, Finland
Arch Intern Med 168:1968-74. 2008..This study evaluates the long-term effect of smoking in midlife on health-related quality of life (HRQoL) in old age...
Psychotropic medication and stroke outcomeMinna M Raivio
Am J Psychiatry 162:1027; author reply 1027-8. 2005
A follow-up study found that cardiovascular risk in middle age predicted mortality and quality of life in old ageArto Strandberg
Department of Medicine, Geriatric Clinic, University of Helsinki, Haartmaninkatu 4, FIN-00029 Helsinki, Finland
J Clin Epidemiol 57:415-21. 2004..CONCLUSION: Low cardiovascular risk in middle age was associated with lower mortality, morbidity, and better quality of life in old age 26 years later. The results may support the theory of compression of morbidity...
Impact of viral and bacterial burden on cognitive impairment in elderly persons with cardiovascular diseasesTimo E Strandberg
Department of Medicine, Geriatric Clinic, University of Helsinki, PO Box 340, FIN 00029 HUS Helsinki, Finland
Stroke 34:2126-31. 2003..Inflammation and infectious etiology have been implicated in the pathogenesis of dementia. We sought to investigate whether the seropositivity of common infections was associated with cognitive function...
Low cholesterol, mortality, and quality of life in old age during a 39-year follow-upTimo E Strandberg
Department of Medicine, Geriatric Clinic, University of Helsinki, Finland
J Am Coll Cardiol 44:1002-8. 2004..We assessed the impact of serum cholesterol level in early midlife on total mortality during up to 39 years of follow-up and on the quality of life (QoL) in old age...
Alcohol consumption, 29-y total mortality, and quality of life in men in old ageArto Y Strandberg
Department of Medicine, Geriatric Clinic, University of Helsinki, Helsinki, Finland
Am J Clin Nutr 80:1366-71. 2004..The negative effects of excessive alcohol consumption are well known, but moderate alcohol consumption is advocated for health reasons...
Prognostic significance of delirium in frail older peopleKaisu H Pitkala
Department of Medicine, Geriatric Clinic, Helsinki University Hospital, Helsinki, Finland
Dement Geriatr Cogn Disord 19:158-63. 2005..86, 95% CI 1.1-3.1), at 2 years (OR 1.76, 95% CI 1.1-2.8), and for permanent institutionalization (OR 2.45, 95% CI 1.2-4.9). Delirious patients with prior dementia tended to have a better prognosis than those without...
Physical and cognitive functioning and resuscitation preferences of aged patientsMarja-Lilsa Laakkonen
J Am Geriatr Soc 53:168-70. 2005
The impact of different diagnostic criteria on prevalence rates for deliriumJouko V Laurila
Geriatric Clinic, Department of Medicine, Helsinki University Hospital, HUS, Finland
Dement Geriatr Cogn Disord 16:156-62. 2003..The DSM-IV and ICD-10 had the largest number of patients not overlapping with any other diagnostic group. The newest DSM-IV classification found more cases of delirium especially among acutely ill, hospitalized patients...
Sweet babies: chocolate consumption during pregnancy and infant temperament at six monthsKatri Raikkonen
Department of Psychology, P O Box 9, 00014 University of Helsinki, Helsinki, Finland
Early Hum Dev 76:139-45. 2004..Chocolate contains several biologically active components potentially having behavioral and psychological consequences...
Clinical findings, outcome and treatment in patients > or = 75 years with acute myocardial infarctionMervi Kotamäki
Department of Medicine, Division of Cardiology, University of Helsinki, Finland
Eur J Epidemiol 18:781-6. 2003..Our aim was to characterize current clinical course, medication and invasive treatment in elderly patients with AMI, compare treatment between sexes and also with data from 1994...
Inappropriate drug prescribing in home-dwelling, elderly patients: a population-based surveyKaisu H Pitkala
Department of Medicine, Geriatric Clinic, Helsinki University Hospital, Finland
Arch Intern Med 162:1707-12. 2002..In 1997, a US expert panel developed explicit criteria on potentially inappropriate drugs for the general elderly population...
Preterm birth and licorice consumption during pregnancyTimo E Strandberg
Department of Medicine, University of Helsinki, Finland
Am J Epidemiol 156:803-5. 2002..07, 95% confidence interval: 1.17, 8.05 for the fully adjusted model). In conclusion, heavy glycyrrhizin exposure was associated with preterm delivery and may be a novel marker of this condition...
Differing effects of oral and transdermal hormone replacement therapy on cardiovascular risk factors in healthy postmenopausal womenTimo E Strandberg
Department of Medicine, Geriatric Clinic, University of Helsinki, PO Box 340, FIN-00029 HUS, Finland
Am J Cardiol 92:212-4. 2003
Possibilities of multifactorial cardiovascular disease prevention in patients aged 75 and older: a randomized controlled trial: Drugs and Evidence Based Medicine in the Elderly (DEBATE) StudyTimo E Strandberg
Department of Medicine, Geriatric Clinic and Division of Cardiology, University of Helsinki, Helsinki, Finland
Eur Heart J 24:1216-22. 2003..The aim of this pre-planned, first-year analysis of the Drugs and Evidence-Based Medicine in the Elderly (DEBATE) Study was to determine the feasibility of prevention efforts in elderly cardiovascular patients...
Management of nonmalignant pain in home-dwelling older people: a population-based surveyKaisu H Pitkala
Helsinki University Hospital, Department of Medicine, Geriatric Clinic, Helsinki, Finland
J Am Geriatr Soc 50:1861-5. 2002....
Risk factors for preterm deliveryTimo E Strandberg
Lancet 361:436; author reply 436-7. 2003
What is the most important component of blood pressure: systolic, diastolic or pulse pressure?Timo E Strandberg
Department of Medicine, Geriatric Clinic, University of Helsinki, Helsinki, Finland
Curr Opin Nephrol Hypertens 12:293-7. 2003..In this review we compare the relative importance of various blood pressure components...
Delirium among patients with and without dementia: does the diagnosis according to the DSM-IV differ from the previous classifications?Jouko V Laurila
Department of Medicine, Helsinki University Hospital, Geriatric Clinic, Helsinki, Finland
Int J Geriatr Psychiatry 19:271-7. 2004..It is not known how DSM-IV classification, compared with the DSM-III, DSM-III-R, and ICD-10, identifies delirium among individuals with and without dementia and whether the symptom profiles differ between these two subgroups...
Predictors of cognitive decline and mortality of aged people over a 10-year periodReijo S Tilvis
Geriatric Clinic, Department of Medicine, Helsinki University Central Hospital, Finland
J Gerontol A Biol Sci Med Sci 59:268-74. 2004..According to the hypothesis of our 10-year prospective study, the predictive values of different risk indicators change over time in a general 75+ population...
Isolated diastolic hypertension, pulse pressure, and mean arterial pressure as predictors of mortality during a follow-up of up to 32 yearsTimo E Strandberg
Department of Medicine, Geriatric Clinic, University of Helsinki
J Hypertens 20:399-404. 2002..To compare mortality associated with various blood pressure components in middle-aged men during up to 32 years of follow-up...
Social contacts and their relationship to loneliness among aged people - a population-based studyPirkko E Routasalo
Department of Nursing Science, University of Turku, Finland
Gerontology 52:181-7. 2006..This has implications for practice. Interventions aiming at relieving loneliness should be focused on enabling an individual to reflect her own expectations and inner feelings of loneliness...
Do gestational age and weight for gestational age predict concordance in parental perceptions of infant temperament?Anu Katriina Pesonen
Department of Psychology, University of Helsinki, PO Box 9, FI 00014 Helsinki, Finland
J Pediatr Psychol 31:331-6. 2006..To study whether infant weight for gestational age, and gestational age predict mother- and father-rated infant temperament (IBQ) at 6 months...
Older people's reasoning for resuscitation preferences and their role in the decision-making processMarja Liisa Laakkonen
Helsinki City Hospital Koskela, P O Box 6410, FIN 00099 Helsinki, Finland
Resuscitation 65:165-71. 2005..To investigate older patients' reasoning for their cardiopulmonary resuscitation (CPR) preferences and the related decision-making process (DMP)...
The MEGA studyTimo E Strandberg
Lancet 368:2051-2; author reply 2052. 2006
Depressive vulnerability in parents and their 5-year-old child's temperament: a family system perspectiveAnu-Katriina Pesonen
Department of Psychology, University of Helsinki, Helsinki, Finland
J Fam Psychol 20:648-55. 2006..The influence of personality-based depressive traits on child temperamental outcomes and effective parenting is discussed with reference to between-dyad family dynamics...
Interaction of herpesviridae, APOE gene, and education in cognitive impairmentTimo E Strandberg
Department of Medicine, Geriatric Clinic, University of Helsinki, P O Box 340, FIN 00029 HUS, Finland
Neurobiol Aging 26:1001-4. 2005....
Diagnosis and treatment of dyslipidemia are neglected in patients with peripheral artery diseaseHeikki Poussa
Department of Surgery, University of Helsinki, Finland
Scand Cardiovasc J 41:138-41. 2007..Our aim was to investigate how dyslipidemia was diagnosed and treated in patients with peripheral artery disease (PAD) in a university vascular clinic...
The association between weight gain up to midlife, 30-year mortality, and quality of life in older menTimo E Strandberg
Arch Intern Med 167:2260-1. 2007
Statin treatment is associated with clearly reduced mortality risk of cardiovascular patients aged 75 years and olderTimo E Strandberg
J Gerontol A Biol Sci Med Sci 63:213-4; author reply 214. 2008
Health-related quality of life in elderly patients with familial hypercholesterolemiaLaura Hyttinen
North Karelia Central Hospital, Joensuu, Finland
Int J Technol Assess Health Care 24:228-34. 2008..The aim of this study was to analyze the health-related quality of life (HRQoL) of elderly patients with FH...
Living will, resuscitation preferences, and attitudes towards life in an aged populationMarja Liisa Laakkonen
Helsinki City Hospital Koskela, Helsinki, Finland
Gerontology 50:247-54. 2004..The growth of life-sustaining medical technology and greater attention to medical care at the end of life have provoked interest in issues related to advance care planning...
Use of inappropriate medications and their prognostic significance among in-hospital and nursing home patients with and without dementia in FinlandMinna M Raivio
Department of General Internal Medicine and Geriatrics, University of Helsinki, Finland
Drugs Aging 23:333-43. 2006..This study examines the use of inappropriate drugs and their impact on mortality and use of health services among Finnish elderly nursing home and hospital patients. Patients with dementia were studied as a special subgroup...
