Osamu Shimmi


Affiliation: University of Helsinki
Country: Finland


  1. Shimmi O, Newfeld S. New insights into extracellular and post-translational regulation of TGF-β family signalling pathways. J Biochem. 2013;154:11-9 pubmed publisher
    ..Extension of the ubiquitylation data to the Hippo pathway is also discussed. ..
  2. Gui J, Huang Y, Montanari M, Toddie Moore D, Kikushima K, Nix S, et al. Coupling between dynamic 3D tissue architecture and BMP morphogen signaling during Drosophila wing morphogenesis. Proc Natl Acad Sci U S A. 2019;: pubmed publisher
  3. Huang Y, Hatakeyama M, Shimmi O. Wing vein development in the sawfly Athalia rosae is regulated by spatial transcription of Dpp/BMP signaling components. Arthropod Struct Dev. 2018;47:408-415 pubmed publisher
    ..Taken together, our data suggest that spatial transcription of core- and co-factors of the BMP pathway sustain localized BMP signaling during sawfly wing vein development. ..
  4. Künnapuu J, Tauscher P, Tiusanen N, Nguyen M, Löytynoja A, Arora K, et al. Cleavage of the Drosophila screw prodomain is critical for a dynamic BMP morphogen gradient in embryogenesis. Dev Biol. 2014;389:149-59 pubmed publisher
    ..These data reveal novel mechanisms by which post-translational regulation of Scw can modulate Dpp signaling activity. ..
  5. Shimmi O, Matsuda S, Hatakeyama M. Insights into the molecular mechanisms underlying diversified wing venation among insects. Proc Biol Sci. 2014;281:20140264 pubmed publisher
    ..Extension of these observations in some winged insects will provide further insights into the mechanisms underlying diversified wing venation among insects. ..
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    Tauscher P, Gui J, Shimmi O. Adaptive protein divergence of BMP ligands takes place under developmental and evolutionary constraints. Development. 2016;143:3742-3750 pubmed
    ..Furthermore, gain and loss of N-glycosylation motifs in conserved signaling molecules under evolutionary constraints appear to constitute flexible modules to adapt to developmental processes. ..