Research Topics
| R K SalokangasSummaryAffiliation: University of Turku Country: Finland Publications
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Publications
Women have later onset than men in schizophrenia--but only in its paranoid form. Results of the DSP projectRaimo K R Salokangas
Department of Psychiatry, Psychiatric Clinic, Turku University Central Hospital, Turku Mental Health Centre, 20520 Turku, Finland
Eur Psychiatry 18:274-81. 2003..It is suggested that there is no gender difference in AOI in early onset schizophrenia. In later onset, paranoid schizophrenia, the illness seems to manifest in women later than in men...
Psychosocial outcome in patients at clinical high risk of psychosis: a prospective follow-upRaimo K R Salokangas
Department of Psychiatry, University of Turku, 20520, Turku, Finland
Soc Psychiatry Psychiatr Epidemiol 48:303-11. 2013..In patients at clinical high risk (CHR) of psychosis, transition to psychosis has been the focus of recent studies. Their broader outcome has received less attention. We studied psychosocial state and outcome in CHR patients...- Axis I diagnoses and transition to psychosis in clinical high-risk patients EPOS project: prospective follow-up of 245 clinical high-risk outpatients in four countriesRaimo K R Salokangas
Department of Psychiatry, University of Turku, Turku, Finland
Schizophr Res 138:192-7. 2012..It is not known how clinical diagnoses correspond to or even predict transitions to psychosis (TTP). Our aim was to examine distributions of life-time and current Axis I diagnoses, and their association with TTP in CHR patients... - Perceived negative attitude of others predicts transition to psychosis in patients at risk of psychosisR K R Salokangas
Department of Psychiatry, University of Turku, 20520 Turku, Finland
Eur Psychiatry 27:264-6. 2012..2009) suggested that the subjective experience of negative attitude of others (NAO) towards oneself is an early indicator of psychotic development. The aim of this prospective follow-up study was to test this hypothesis... - Medical problems in schizophrenia patients living in the community (alternative facilities)Raimo K R Salokangas
Department of Psychiatry, University of Turku, Psychiatric Clinic, Turku University Central Hospital, Turku Psychiatric Clinic, Turku, Finland
Curr Opin Psychiatry 20:402-5. 2007..A great majority of schizophrenia patients live in the community and in alternative facilities. This review aims to report studies on medical problems in patients living in the community... - Negative symptoms and neuroleptics in catatonic schizophreniaRaimo K R Salokangas
Department of Psychiatry, University of Turku, FIN 20520 Turku, Finland
Schizophr Res 59:73-6. 2003..046) higher ND scores than other patients. Patients with catatonic schizophrenia are highly vulnerable to negative symptoms related to neuroleptic drugs, probably because of a defect in their dopaminergic neuronal pathways... - Vulnerability to psychosis in patients attending primary and psychiatric care. Results of the RADEP studyRaimo K R Salokangas
Department of Psychiatry, University of Turku, Finland
Nord J Psychiatry 59:239-45. 2005..In primary care, vulnerability to psychosis is associated with the patient's background more strongly than in psychiatric care. Concurrent occurrence of psychotic symptoms with manic and depressive symptoms is common... - Body mass index and functioning in long-term schizophrenia. Results of the DSP projectRaimo K R Salokangas
Department of Psychiatry, University of Turku Psychiatric Clinic, Turku University Central Hospital, Turku Psychiatric Clinic, Kiinamyllynkatu 4 8, FI 20520 Turku, Finland
Eur Psychiatry 22:313-8. 2007..The study evaluates the association of body mass index (BMI) with functioning in male and female patients with long-term schizophrenia... - Incidence of hospitalised schizophrenia in Finland since 1980: decreasing and increasing againRaimo K R Salokangas
Department of Psychiatry, University of Turku, Turku, Finland
Soc Psychiatry Psychiatr Epidemiol 46:343-50. 2011..We studied the annual first-admission rate (per 100,000) for schizophrenia (FARsch) during a rapid deinstitutionalisation period in Finland... - Psychotism and its dimensions in primary care. Associations with patient's background and manic and depressive symptoms. Results of the RADEP studyRaimo K R Salokangas
Department of Psychiatry, University of Turku, Turku, Finland
Nord J Psychiatry 60:492-500. 2006..Independently of patients' background, manic widely and depressive symptoms less widely associate with occurrence of psychotism... - Early detection and intervention of psychosis. A reviewRaimo K R Salokangas
Department of Psychiatry, University of Turku, Turku, Finland
Nord J Psychiatry 62:92-105. 2008..However, more large-scale studies and clinical case descriptions of treatment of patients with sub-threshold psychotic symptoms are needed... - Gender and the use of neuroleptics in schizophreniaRaimo K R Salokangas
Department of Psychiatry, University of Turku, Finland
Schizophr Res 66:41-9. 2004.... - Subjective life satisfaction and living situations of persons in Finland with long-term schizophreniaRaimo K R Salokangas
Department of Psychiatry, University of Turku and Turku Psychiatric Clinic, Finland
Psychiatr Serv 57:373-81. 2006..This study measured subjective life satisfaction among patients with long-term schizophrenia who were living in the community... - Structural magnetic resonance imaging in patients with first-episode schizophrenia, psychotic and severe non-psychotic depression and healthy controls. Results of the schizophrenia and affective psychoses (SAP) projectR K R Salokangas
Department of Psychiatry, University of Turku, Turku University Central Hospital and Turku Psychiatric Clinic, Finland
Br J Psychiatry Suppl 43:s58-65. 2002..Structural brain abnormalities are prevalent in patients with schizophrenia and affective disorders... - Gender differences in depressive symptoms. An artefact caused by measurement instruments?Raimo K R Salokangas
Department of Psychiatry, University of Turku Psychiatric Clinic, Turku University Central Hospital Turku Psychiatric Clinic, FIN 20520, Turku, Finland
J Affect Disord 68:215-20. 2002..According to studies depression and depressive symptoms are more prevalent in females than in males. It is possible, however, that instruments meant to measure depressiveness are gender-biased... - High levels of dopamine activity in the basal ganglia of cigarette smokersR K Salokangas
Department of Psychiatry, Turku University Central Hospital, Finland
Am J Psychiatry 157:632-4. 2000..The authors' goal was to study presynaptic dopamine activity in smoking and nonsmoking human subjects in vivo... - Vulnerability to psychosis increases the risk of depression. Results of the RADEP studyRaimo K R Salokangas
Department of Psychiatry, University of Turku, Turku, Finland
Nord J Psychiatry 61:393-402. 2007..Therefore, vulnerability to psychosis should be evaluated when treatment intervention for patients with depressive symptoms is planned... - Perceived negative attitude of others as an early sign of psychosisRaimo K R Salokangas
Department of Psychiatry, University of Turku, Turku, Finland
Eur Psychiatry 24:233-8. 2009..We studied the associations of psychiatric outpatients' self-reported functioning and interpersonal relationships with vulnerability to and risk of psychosis... - Mortality in chronic schizophrenia during decreasing number of psychiatric beds in FinlandRaimo K R Salokangas
Department of Psychiatry, University of Turku, Psychiatric Clinic, Turku University Central Hospital, Turku Mental Health Centre, FIN 20520, Turku, Finland
Schizophr Res 54:265-75. 2002..In outpatient treatment, it is important to remember that the risk of unnatural death increases during the first years after discharge from hospital... - Comparison of clinical and best-estimate research DSM-IV diagnoses in a Finnish sample of first-admission psychosis and severe affective disorderT Taiminen
Department of Psychiatry, University of Turku, Rakennus 9, III kerros, Kunnallissairaalantie 20, FI-20700 Turku, Finland
Nord J Psychiatry 55:107-11. 2001..In conclusion, hospital diagnoses were not reliable in first-episode patients. Inappropriate diagnoses may compromise both treatment and epidemiologic findings based on discharge diagnoses... - Depressive symptoms and presynaptic dopamine function in neuroleptic-naive schizophreniaJ Hietala
Department of Psychiatry, Turku University Central Hospital, Finland
Schizophr Res 35:41-50. 1999..g., in prediction of response to D2 receptor blocking antipsychotic drugs. A possible connection between paranoid symptomatology and subcortical hyperdopaminergia is suggested, but this remains to be further verified... - Habituation of the blink reflex in first-episode schizophrenia, psychotic depression and non-psychotic depressionT Taiminen
Department of Psychiatry, University of Turku, Kunnallissairaalantie 20, FIN 20700, Turku, Finland
Schizophr Res 44:69-79. 2000.... - First-contact rate for schizophrenia in community psychiatric care. Consideration of the oestrogen hypothesisR K Salokangas
Department of Psychiatry, University of Turku, Finland
Eur Arch Psychiatry Clin Neurosci 242:337-46. 1993.... - To be or not to be married--that is the question of quality of life in men with schizophreniaR K Salokangas
Department of Psychiatry, University of Turku Psychiatric Clinic, Turku University Central Hospital, Finland
Soc Psychiatry Psychiatr Epidemiol 36:381-90. 2001..The results of this study strongly emphasise that the associations between gender, marital status and QoL to a great extent depend on the study sample and may also vary by study area... - Substance abuse and related diagnoses in early psychosisJyrki A Korkeila
Department of Psychiatry, Turku City Hospital and Turku University Central Hospital, University of Turku, Finland
Compr Psychiatry 46:447-52. 2005..The odds ratio for having an SUD among those vulnerable to psychosis was 6.33 (95% confidence interval, 1.77-22.73). Early psychosis and substance abuse frequently occur together... - Symptom dimensions and their association with outcome and treatment setting in long-term schizophrenia. Results of the DSP projectRaimo K R Salokangas
Department of Psychiatry, University of Turku, Turku University Central Hospital, FI-20520 Turku, Finland
Nord J Psychiatry 56:319-27. 2002..A dimensional approach, instead of a categorical one, seems to be important in assessing symptomatology and its relation to outcome and interventions in schizophrenia... - Cognitive impairment and the 10-year survival probability of a normal 62-year-old populationR Portin
Department of Neurology, University of Turku and Turku University Central Hospital, Finland
Scand J Psychol 42:359-66. 2001..Thus, memory impairment may reflect very early signs of underlying disease, and so the findings provide predictive validity for the cognitive methods used... - The Depression Scale (DEPS) as a case finder for depression in various subgroups of primary care patientsOuti Poutanen
University of Tampere, Medical School Tampere University Hospital, Psychiatric Clinic, P O Box 607, Teiskontie 35, Tampere 33014, Finland
Eur Psychiatry 23:580-6. 2008..The quick and simple Depression Scale (DEPS) has been a popular self-rating depression scale in Finland for nearly 15 years. The purpose was to assess the validity of the DEPS in various subgroups of patients... - Weak sense of coherence predicts depression: 1-year and 9-year follow-ups of the Finnish Outcomes of Depression International Network (ODIN) sampleSinikka Luutonen
Department of Psychiatry, University of Turku, Turku, Finland
J Ment Health 20:43-51. 2011..Previous studies show conflicting results on the role of weak sense of coherence (SOC) as a risk factor for depression... - Physical ill health and risk of psychosisJyrki A Korkeila
Department of Psychiatry, University of Turku, 20700 Turku, Finland
Psychiatry Res 150:255-63. 2007..33) had significantly more commonly physician-diagnosed illnesses than those who had no diagnosis or any other diagnosis. Physical ill health seems to be common among those vulnerable to psychosis... - Gender differences in the symptoms of major depression and in the level of social functioning in public primary care patientsOuti Poutanen
University of Tampere, Medical School Tampere University Hospital, Psychiatric Clinic, Finland
Eur J Gen Pract 15:161-7. 2009..There are no great differences in the symptom profiles of depression between the genders in observer rating scales, but women self-report more symptoms... - The outcomes of interpersonal counselling on depressive symptoms and distress after myocardial infarctionOlli Oranta
Department of Nursing Science and Psychiatric Clinic, Turku University Central Hospital, Turku, Finland
Nord J Psychiatry 64:78-86. 2010..Depression is not treated adequately after myocardial infarction (MI). This study evaluates the interpersonal counselling (IPC) implemented by a registered nurse on outcomes for depressive symptoms and distress in MI patients... - Differentiating adolescents at clinical high risk for psychosis from psychotic and non-psychotic patients with the RorschachTuula Ilonen
University of Turku, Department of Psychiatry, FIN 20700 Turku, Finland
Psychiatry Res 179:151-6. 2010..Our results suggest perceptual and thought disturbance as an important indicator of vulnerability to psychosis... - Predicting lifetime mood elevation in primary care patients and psychiatric patientsOuti Poutanen
University of Tampere, Medical School Tampere University Hospital, Psychiatric Clinic, Tampere, Finland
Nord J Psychiatry 62:263-71. 2008..Quick and easy questions about smoking and difficulties in making contact with the opposite sex may improve the detection of mood elevation... - The Depression Scale as a screening instrument for a subsequent depressive episode in primary healthcare patientsOuti Poutanen
Department of Psychiatry, Medical School, University of Tampere and Psychiatric Clinic, Tampere University Hospital, Finland
Br J Psychiatry 191:50-4. 2007..There are numerous instruments for screening for depression. A feasible screen is good at both recognising and predicting depression... - Use of antidepressants and suicide rate in Finland: an ecological studyJyrki Korkeila
Department of Psychiatry, University of Turku, Finland
J Clin Psychiatry 68:505-11. 2007..The suicide rate has decreased in many countries, while the use of antidepressants has increased greatly. The aim of this study was to investigate the associations between use of antidepressants and suicide rate... - Quality of life and functioning ability in subjects vulnerable to psychosisTanja Svirskis
Department of Psychiatry, University of Turku, 20700 Turku, Finland
Compr Psychiatry 48:155-60. 2007..It is well established that quality of life (QOL) and functioning ability are impaired in psychosis, especially schizophrenia. Little is known about QOL and functioning in subjects vulnerable to psychosis (VTP)... - Striatal dopamine synthesis in first-degree relatives of patients with schizophreniaJukka Huttunen
Department of Psychiatry, University of Turku, Turku, Finland
Biol Psychiatry 63:114-7. 2008..We investigated whether this same phenomenon is shared by individuals with increased genetic risk for schizophrenia... - Personality traits and striatal dopamine synthesis capacity in healthy subjectsAki Laakso
Department of Pharmacology and Clinical Pharmacology, University of Turku, Kiinamyllynkatu 4-8, 20520 Turku, Finland
Am J Psychiatry 160:904-10. 2003..Together with previous studies, they also indicate differential involvement of various components of the dopaminergic system in normal and pathological personality traits... - Neuropsychological subtyping of schizophreniaTuula Ilonen
Department of Psychiatry, Turku University Central Hospital, University of Turku, Kunnallissairaalantie 20, FIN 20520 Turku, Finland
Psychiatry Res 129:191-9. 2004..Neuropsychological assessment, covering a range of functional domains of the major dimensions of behavior, has an important role in identifying preserved and impaired capacities, in predicting outcome, and in planning treatment... - Cognitive functioning and expressed emotion among patients with first-episode severe psychiatric disordersJyrki Heikkilä
City of Turku Municipal Health Care Department, Psychiatry, Kunnallissairaalantie 20, rak 4, FIN 20700, Turku, Finland
Compr Psychiatry 47:152-8. 2006..Our results favor the attribution hypothesis of EE instead of the hypothesis that patient psychopathology would explain EE. Good cognitive functioning may lead to higher EE scores because of the higher expectations by the relatives... - Sex differences in striatal presynaptic dopamine synthesis capacity in healthy subjectsAki Laakso
Department of Pharmacology and Clinical Pharmacology, University of Turku, Finland
Biol Psychiatry 52:759-63. 2002..This finding may be associated with sex differences in vulnerability and clinical course of neuropsychiatric disorders with dopaminergic dysregulation, e.g., schizophrenia, alcohol dependence, and Parkinson's disease... - Stability of affect associated with autobiographical memoriesOuti Poutanen
University of Tampere Medical School, Tampere University Hospital, Psychiatric Clinic, Finland
Nord J Psychiatry 63:223-30. 2009..Future long follow-up studies with more specific multi-item measures on family atmosphere are needed... - MRI findings and Axis I and II psychiatric disorders after traumatic brain injury: a 30-year retrospective follow-up studySalla Koponen
Department of Psychiatry, Turku University Hospital, PL 52, FI 20521 Turku, Finland
Psychiatry Res 146:263-70. 2006.... - Axis-I disorders and vulnerability to psychosisTanja Svirskis
University of Turku, Department of Psychiatry, Kunnallissairaalantie 20 rak, 9 20700 Turku, Finland
Schizophr Res 75:439-46. 2005..The psychopathology that manifests during the prodromal phase of first-episode psychosis is varied. Little is known about the clinical diagnoses of subjects with so-called prodromal or psychotic-like symptoms... - Violent victimization in schizophreniaTeija Honkonen
Section of Neurosciences, Finnish Institute of Occupational Health, Topeliuksenkatu 41aA, 00250 Helsinki, Finland
Soc Psychiatry Psychiatr Epidemiol 39:606-12. 2004..We investigated the 3-year prevalence, and the sociodemographic and clinical correlates of violent victimization in a large and unselected nationwide sample of deinstitutionalized patients with schizophrenia... - [Hallucination--a neurologic or psychiatric disorder?]Raimo K R Salokangas
TYKS n Psykiatrian Klinikka, Turku
Duodecim 120:2085-92. 2004 - Alexithymia and childhood abuse among patients attending primary and psychiatric care: results of the RADEP StudyMatti Joukamaa
Tampere School of Public Health, University of Tampere, Tampere, Finaland
Psychosomatics 49:317-25. 2008..Some authors have suggested that the background of alexithymia is related to affective development during early childhood... - Factors associated with being granted a pension among psychiatric outpatients with major depressionMarko Sorvaniemi
Psychiatric Policlinic of Rauma, Satakunta Hospital District, Steniuksenkatu 2, 26100 Rauma, Finland
J Affect Disord 75:43-8. 2003..We examined to what extent major depression leads to disability pension and whether there are any associated factors with being granted a pension... - Prevalence of bipolar disorder and major depression among patients seen in primary and secondary care in FinlandMarko P Sorvaniemi
Can J Psychiatry 50:186-7. 2005 - Alexithymia and life satisfaction in primary healthcare patientsAino K Mattila
Tampere School of Public Health, FIN 33014, Tampere, Finland
Psychosomatics 48:523-9. 2007..2% were depressed. Alexithymia was negatively associated with life satisfaction even when depression and other confounding factors were controlled for. Alexithymia is a risk factor for life dissatisfaction in primary-care patients... - Schizophrenic patients in different treatment settings during the era of deinstitutionalization: three-year follow-up of three discharge cohorts in FinlandTeija Honkonen
Section of Clinical Neurosciences, Finnish Institute of Occupational Health, Topeliuksenkatu 41aA, FIN 00250 Helsinki, Finland
Aust N Z J Psychiatry 37:160-8. 2003..Furthermore, we examined secular changes in these phenomena during the era of rapid deinstitutionalization in Finland... - [Older antipsychotic drugs have proven to be equally effective with the newer treatments]Raimo K R Salokangas
Turun yliopisto ja TYKS:n psykiatrian klinikka, Turku
Duodecim 121:2617-9. 2005 - Employment predictors for discharged schizophrenia patientsTeija Honkonen
Finnish Institute of Occupational Health, Topeliuksenkatu 41aA, Helsinki, Finland
Soc Psychiatry Psychiatr Epidemiol 42:372-80. 2007..To investigate predictors for competitive employment in a three-year follow-up study of discharged schizophrenia patients... 
Recruitment and treatment practices for help-seeking "prodromal" patientsThomas H McGlashan
Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA
Schizophr Bull 33:715-26. 2007..References for details are noted...- Regional brain morphology and duration of illness in never-medicated first-episode patients with schizophreniaJarmo Hietala
Schizophr Res 64:79-81. 2003 - Cancer mortality among elderly patients with brief psychotic disorderLiisi Bashmakov
Int J Geriatr Psychiatry 17:488-9. 2002 - Sick-leave certificates granted to psychiatric outpatients with major depressionMarko Sorvaniemi
Psychiatric Sector, Satakunta Hospital District, Rauma, Finland
Depress Anxiety 17:220-3. 2003..Eighty-seven percent of the total sum of sick-leave days was for depressive disorders. Living with someone else, being employed, and early recognition of the illness were associated with the granted sick-leaves... - The amygdala and schizophrenia: a volumetric magnetic resonance imaging study in first-episode, neuroleptic-naive patientsChristian C Joyal
, Montreal, Canada
Biol Psychiatry 54:1302-4. 2003..No significant correlations were found between the amygdaloid volumes and either the duration of the disease or the symptom severity. CONCLUSIONS:Amygdaloid volume anomalies are already present in the early phases of schizophrenia... - Dapoxetine for treatment of premature ejaculationRaimo K R Salokangas
Lancet 368:1649; author reply 1649-50. 2006 - The performance of diagnostic measures of depression in alexithymic and nonalexithymic subjectsAino K Mattila
Tampere School of Public Health, University of Tampere, FIN 33014 Tampere, Finland
Gen Hosp Psychiatry 30:77-9. 2008..The objective of this study was to examine how the outcomes of a structured diagnostic interview for depression are related to the results of a self-report scale in alexithymic and nonalexithymic groups... - A prospective, multicentre, open-label study of aripiprazole in the management of patients with schizophrenia in psychiatric practice in Europe: Broad Effectiveness Trial with Aripiprazole in Europe (EU-BETA)Jurgen Wolf
Department of Psychiatry, Charite University Medicine Berlin, Campus Benjamin Franklin, Berlin, Germany
Curr Med Res Opin 23:2313-23. 2007..To examine the effectiveness of aripiprazole in schizophrenia in a naturalistic setting in 14 European countries... - [Symptoms preceding psychosis]Tanja Suomela
TYKS:n psykiatrian klinikka, Turku
Duodecim 120:1827-30. 2004 - A volumetric MRI study of the entorhinal cortex in first episode neuroleptic-naive schizophreniaChristian C Joyal
, Montreal, Canada
Biol Psychiatry 51:1005-7. 2002..This volume loss did not correlate with items on the Positive and Negative Syndrome Scale. CONCLUSIONS: These data suggest early involvement of the entorhinal cortex in schizophrenia...