Samuli I Saarni

..More detailed molecular information on the metabolic abnormalities may reveal clues about the pathophysiology of these changes, as well as about disease specificity...

..Health utility and quality of life (QoL) are increasingly important outcome measures in healthcare and health economics...

..Obesity should be treated like other diseases in health care, and obesity surgery rationed like other cost-effective treatments. Positive actions to ensure patient autonomy and just access to surgical treatments may be warranted...

..Integrating ethical considerations into HTA can improve the relevance of technology assessments for health care and health policy in both developed and developing countries...

..One reason for this is lack of knowledge about the properties and differences between the methods available. This study compares different methods for ethical analysis within HTA...

..We investigated how the frequency and types of ethically difficult treatment decisions vary by specialty...

..Whether all physicians actually experience ethical problems, what these problems are and how they vary according to physician age, gender and work sector are largely unknown...

..To examine the associations between alcohol consumption and utility-based health-related quality of life (HRQoL), subjective quality of life (QoL), self-rated health (SRH), and mental distress...

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..We investigated which domains of HRQoL are associated with work status...

..We investigated the impact of major chronic conditions on HRQoL using 15D and EQ-5D in a representative sample of Finns...

..Measurement of health-related quality of life (HRQoL) with generic preference-based instruments enables comparisons of severity across different conditions and treatments. This is necessary for rational public health policy...

..Here we chart some of these major philosophical issues and show why simple solutions cannot be found. The profession needs to pay more attention to different uses of EBM in order to preserve the good aspects of professionalism...

..The incidence of SUDs peaks by young adulthood making epidemiological studies of SUDs in young adults informative...

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..We examined the geographical variation in the lifetime prevalence of psychotic disorders in a comprehensive general population study...

..Mood symptoms may not explain the difference between the diagnostic groups in cognitive functions, but the difference may be related to differences in the severity of negative symptoms...

..Our results emphasize the importance of using control samples derived from the same population and studied similarly as those with disorders in evaluating cognitive functioning of subjects with severe mental disorders...

..The aim of the study is to investigate in a general population the prevalence of impaired habitual VA and self-reported difficulties in vision among persons with different psychotic disorders...

..Recent general population surveys of psychotic disorders have found low lifetime prevalences. However, this may be owing to methodological problems. Few studies have reported the prevalences of all specific psychotic disorders...

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..Mental disorders are associated with increased mortality, but population-based surveys with reliable diagnostic procedures controlling for somatic health status are scarce...

..To determine the prevalence of metabolic syndrome and investigate its components in individuals with psychotic disorders and individuals using antipsychotic medication in a general population study...

..There may be an association between cognitive functioning and burnout, but this has previously been investigated in only few studies, all using clinical samples...

..Schizophrenia seems to be associated with low bone mineral density through a still unclear mechanism, although information on other psychotic disorders is scarce...

..Our aim was to investigate mobility limitations among subjects with psychotic disorder in a general population-based sample...

..We investigated mortality and its determinants in people with psychotic disorder...

..We tested the validity of the SCOFF, a five-question screening instrument for eating disorders, in a general population sample...

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..Because the shortage of exposure to daylight or artificial bright light has been linked to the occurrence of the seasonal changes, we wanted to know whether illumination indoors contributes to the HRQoL...

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..This is important, as both SWB and health utility can be important aims of health policy and instruments in resource allocation...

..The aim of this study was to develop and test a generic framework to enable international collaboration for producing and sharing results of health technology assessments (HTAs)...

..We examined the detailed body composition of people with different psychotic disorders in a large population-based sample...

..The present study extends our previous work by examining the effects of psychiatric co-morbidity and other disorder characteristics on depression-related cognitive functioning...

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