Silva Saarinen

Summary

Affiliation: University of Helsinki
Country: Finland

Publications

  1. doi request reprint Analysis of a Finnish family confirms RHBDF2 mutations as the underlying factor in tylosis with esophageal cancer
    Silva Saarinen
    Department of Medical Genetics, Genome Scale Biology Research Program, University of Helsinki, Helsinki, Finland
    Fam Cancer 11:525-8. 2012
  2. ncbi request reprint High familial risk in nodular lymphocyte-predominant Hodgkin lymphoma
    Silva Saarinen
    University of Helsinki, Helsinki, Finland
    J Clin Oncol 31:938-43. 2013
  3. pmc Nationwide registry-based analysis of cancer clustering detects strong familial occurrence of Kaposi sarcoma
    Eevi Kaasinen
    Genome Scale Biology Research Program, and Department of Medical Genetics, Faculty of Medicine, University of Helsinki, Helsinki, Finland
    PLoS ONE 8:e55209. 2013
  4. doi request reprint Primary mediastinal large B-cell lymphoma segregating in a family: exome sequencing identifies MLL as a candidate predisposition gene
    Silva Saarinen
    Department of Medical Genetics, University of Helsinki, Helsinki, Finland
    Blood 121:3428-30. 2013
  5. doi request reprint Exome sequencing reveals germline NPAT mutation as a candidate risk factor for Hodgkin lymphoma
    Silva Saarinen
    Department of Medical Genetics, University of Helsinki, Helsinki, Finland
    Blood 118:493-8. 2011
  6. pmc Rule-based induction method for haplotype comparison and identification of candidate disease loci
    Sirkku Karinen
    Research Programs Unit, Genome Scale Biology, and Institute of Biomedicine, Biochemistry and Developmental Biology, University of Helsinki, Haartmaninkatu 8, Helsinki, FIN 00014, Finland
    Genome Med 4:21. 2012
  7. pmc Loss of SUFU function in familial multiple meningioma
    Mervi Aavikko
    Genome Scale Biology Research Program, University of Helsinki, 00014 Helsinki, Finland
    Am J Hum Genet 91:520-6. 2012

Collaborators

Detail Information

Publications7

  1. doi request reprint Analysis of a Finnish family confirms RHBDF2 mutations as the underlying factor in tylosis with esophageal cancer
    Silva Saarinen
    Department of Medical Genetics, Genome Scale Biology Research Program, University of Helsinki, Helsinki, Finland
    Fam Cancer 11:525-8. 2012
    ..These results enable the genetic counseling and diagnostic mutation screening of the members of TOC families...
  2. ncbi request reprint High familial risk in nodular lymphocyte-predominant Hodgkin lymphoma
    Silva Saarinen
    University of Helsinki, Helsinki, Finland
    J Clin Oncol 31:938-43. 2013
    ..We conducted a population-based study by using the Finnish registries and evaluated the familial risk in NLPHL...
  3. pmc Nationwide registry-based analysis of cancer clustering detects strong familial occurrence of Kaposi sarcoma
    Eevi Kaasinen
    Genome Scale Biology Research Program, and Department of Medical Genetics, Faculty of Medicine, University of Helsinki, Helsinki, Finland
    PLoS ONE 8:e55209. 2013
    ..Further work with high-throughput methods should elucidate the molecular basis of the potentially novel predisposition conditions found in this study...
  4. doi request reprint Primary mediastinal large B-cell lymphoma segregating in a family: exome sequencing identifies MLL as a candidate predisposition gene
    Silva Saarinen
    Department of Medical Genetics, University of Helsinki, Helsinki, Finland
    Blood 121:3428-30. 2013
    ..To our knowledge, this is the first time when familial clustering of PMBCL is reported. Although we propose MLL as a candidate predisposition gene for this condition, this finding needs to be validated in additional cases...
  5. doi request reprint Exome sequencing reveals germline NPAT mutation as a candidate risk factor for Hodgkin lymphoma
    Silva Saarinen
    Department of Medical Genetics, University of Helsinki, Helsinki, Finland
    Blood 118:493-8. 2011
    ..11; P = .018). NPAT is thus far the first gene implicated in nodular lymphocyte predominant Hodgkin lymphoma predisposition...
  6. pmc Rule-based induction method for haplotype comparison and identification of candidate disease loci
    Sirkku Karinen
    Research Programs Unit, Genome Scale Biology, and Institute of Biomedicine, Biochemistry and Developmental Biology, University of Helsinki, Haartmaninkatu 8, Helsinki, FIN 00014, Finland
    Genome Med 4:21. 2012
    ..Our analysis of three families with multiple individuals affected by lymphoma identified several interesting haplotypes shared by distantly related patients...
  7. pmc Loss of SUFU function in familial multiple meningioma
    Mervi Aavikko
    Genome Scale Biology Research Program, University of Helsinki, 00014 Helsinki, Finland
    Am J Hum Genet 91:520-6. 2012
    ..It is possible that other genic mutations resulting in aberrant activation of the Hh pathway might underlie meningioma predisposition in families with an unknown etiology...