A M Remes

Summary

Affiliation: University of Oulu
Country: Finland

Publications

  1. pmc Role of MAPT mutations and haplotype in frontotemporal lobar degeneration in Northern Finland
    Anna Lotta Kaivorinne
    Department of Neurology, University of Oulu, Oulu, Finland
    BMC Neurol 8:48. 2008
  2. doi request reprint Parkinsonism associated with the homozygous W748S mutation in the POLG1 gene
    A M Remes
    Department of Neurology, University of Oulu, Box 5000, FIN 90014, Oulu, Finland
    Parkinsonism Relat Disord 14:652-4. 2008
  3. doi request reprint Carbon 11-labeled pittsburgh compound B positron emission tomographic amyloid imaging in patients with APP locus duplication
    Anne M Remes
    Clinical Research Centre, Oulu University Hospital, University of Oulu, Oulu, Finland
    Arch Neurol 65:540-4. 2008
  4. ncbi request reprint A novel mutation of the fumarase gene in a family with autosomal recessive fumarase deficiency
    Anne M Remes
    Department of Neurology, University of Oulu, Oulu, Finland
    J Mol Med (Berl) 82:550-4. 2004
  5. pmc Mitochondrial DNA haplogroups in early-onset Alzheimer's disease and frontotemporal lobar degeneration
    Johanna Krüger
    Institute of Clinical Medicine, Neurology, University of Oulu, Oulu, Finland
    Mol Neurodegener 5:8. 2010
  6. pmc Epidemiology of A3243G, the mutation for mitochondrial encephalomyopathy, lactic acidosis, and strokelike episodes: prevalence of the mutation in an adult population
    K Majamaa
    Department of Neurology, University of Oulu, Oulu, Finland
    Am J Hum Genet 63:447-54. 1998
  7. doi request reprint Low prevalence of progranulin mutations in Finnish patients with frontotemporal lobar degeneration
    J Kruger
    Department of Neurology, University of Oulu, Oulu, Finland
    Eur J Neurol 16:27-30. 2009
  8. ncbi request reprint A 3-year clinical follow-up of adult patients with 3243A>G in mitochondrial DNA
    K A M Majamaa-Voltti
    Department of Internal Medicine, University of Oulu, Oulu, Finland
    Neurology 66:1470-5. 2006
  9. ncbi request reprint Hereditary dementia with intracerebral hemorrhages and cerebral amyloid angiopathy
    A M Remes
    Department of Neurology, University of Oulu, PO Box 5000, FIN 90014 Oulu, Finland
    Neurology 63:234-40. 2004
  10. ncbi request reprint Comprehension of before and after in frontotemporal degeneration
    Merja Karjalainen
    Department of Finnish, Information Studies and Logopedics, University of Oulu, Finland
    Logoped Phoniatr Vocol 30:28-33. 2005

Collaborators

Detail Information

Publications23

  1. pmc Role of MAPT mutations and haplotype in frontotemporal lobar degeneration in Northern Finland
    Anna Lotta Kaivorinne
    Department of Neurology, University of Oulu, Oulu, Finland
    BMC Neurol 8:48. 2008
    ..The H1 haplotype of MAPT has been found to be closely associated with tauopathies and with sporadic FTLD. Our aim was to investigate MAPT mutations and haplotype frequencies in a clinical series of patients with FTLD in Northern Finland...
  2. doi request reprint Parkinsonism associated with the homozygous W748S mutation in the POLG1 gene
    A M Remes
    Department of Neurology, University of Oulu, Box 5000, FIN 90014, Oulu, Finland
    Parkinsonism Relat Disord 14:652-4. 2008
    ..Parkinsonism is one of the phenotypic features associated also with the W748S mutation...
  3. doi request reprint Carbon 11-labeled pittsburgh compound B positron emission tomographic amyloid imaging in patients with APP locus duplication
    Anne M Remes
    Clinical Research Centre, Oulu University Hospital, University of Oulu, Oulu, Finland
    Arch Neurol 65:540-4. 2008
    ..To investigate amyloid accumulation by carbon 11-labeled Pittsburgh Compound B (11C-PiB) in hereditary cerebral amyloid angiopathy and APP locus duplication...
  4. ncbi request reprint A novel mutation of the fumarase gene in a family with autosomal recessive fumarase deficiency
    Anne M Remes
    Department of Neurology, University of Oulu, Oulu, Finland
    J Mol Med (Berl) 82:550-4. 2004
    ..Analysis of the FH mutation and the mutant enzyme variant described here provides an explanation for the mechanism of FH deficiency at the molecular level and paves the way for the analysis of other dysfunctional FH variants...
  5. pmc Mitochondrial DNA haplogroups in early-onset Alzheimer's disease and frontotemporal lobar degeneration
    Johanna Krüger
    Institute of Clinical Medicine, Neurology, University of Oulu, Oulu, Finland
    Mol Neurodegener 5:8. 2010
    ....
  6. pmc Epidemiology of A3243G, the mutation for mitochondrial encephalomyopathy, lactic acidosis, and strokelike episodes: prevalence of the mutation in an adult population
    K Majamaa
    Department of Neurology, University of Oulu, Oulu, Finland
    Am J Hum Genet 63:447-54. 1998
    ..The high prevalence of the common MELAS mutation in the adult population suggests that mitochondrial disorders constitute one of the largest diagnostic categories of neurogenetic diseases...
  7. doi request reprint Low prevalence of progranulin mutations in Finnish patients with frontotemporal lobar degeneration
    J Kruger
    Department of Neurology, University of Oulu, Oulu, Finland
    Eur J Neurol 16:27-30. 2009
    ..The frequency of these mutations varies between populations. The aim of this study was to determine mutations and genetic variations of the PGRN gene in Finnish patients with FTLD and FTLD with associated motor neuron disease (FTLD-MND)...
  8. ncbi request reprint A 3-year clinical follow-up of adult patients with 3243A>G in mitochondrial DNA
    K A M Majamaa-Voltti
    Department of Internal Medicine, University of Oulu, Oulu, Finland
    Neurology 66:1470-5. 2006
    ..To follow the clinical course of patients with the mitochondrial DNA mutation 3243A>G for 3 years...
  9. ncbi request reprint Hereditary dementia with intracerebral hemorrhages and cerebral amyloid angiopathy
    A M Remes
    Department of Neurology, University of Oulu, PO Box 5000, FIN 90014 Oulu, Finland
    Neurology 63:234-40. 2004
    ..Intracerebral hemorrhage occasionally affects patients with AD...
  10. ncbi request reprint Comprehension of before and after in frontotemporal degeneration
    Merja Karjalainen
    Department of Finnish, Information Studies and Logopedics, University of Oulu, Finland
    Logoped Phoniatr Vocol 30:28-33. 2005
    ..The results showed that the patients generally found after constructions more difficult. The difficulty was not, however, related to normal ageing, as was shown by the performance of the control group...
  11. doi request reprint Analysis of functional consequences of haplogroup J polymorphisms m.4216T>C and m.3866T>C in human MT-ND1: mutagenesis of homologous positions in Escherichia coli
    Reetta Hinttala
    Department of Clinical Medicine, Neurology, University of Oulu, 90014 Oulu, Finland
    Mitochondrion 10:358-61. 2010
    ..NADH dehydrogenase domain activity of NDH-1 with either one or both mutations was markedly decreased suggesting that m.4216T>C and m.3866T>C may have an effect on the structural integrity of complex I...
  12. ncbi request reprint Prevalence of large-scale mitochondrial DNA deletions in an adult Finnish population
    A M Remes
    Department of Neurology, University of Oulu, Finland
    Neurology 64:976-81. 2005
    ..Reported case series have suggested that deletions are not uncommon in the population, but their prevalence has not been documented...
  13. doi request reprint Mutations in CHMP2B are not a cause of frontotemporal lobar degeneration in Finnish patients
    A L Kaivorinne
    Department of Clinical Medicine, Neurology, University of Oulu, Oulu, Finland
    Eur J Neurol 17:1393-5. 2010
    ..However, CHMP2B has been showed to be a rare cause of FTLD. Our aim was to determine the frequency of CHMP2B mutations in a clinical series of patients with FTLD in Northern Finland...
  14. doi request reprint Increasing incidence of multiple sclerosis in women in Northern Finland
    O Krökki
    Institute of Clinical Medicine, Neurology, University of Oulu, Oulu, Finland
    Mult Scler 17:133-8. 2011
    ..The geographical distribution of multiple sclerosis (MS) means that prevalence rates increase with latitude north or south of the equator. Temporally, a tendency for increased incidences of MS has been observed over the past two decades...
  15. ncbi request reprint Ubiquinone and nicotinamide treatment of patients with the 3243A-->G mtDNA mutation
    A M Remes
    Department of Neurology, University of Oulu, Oulu, Finland
    Neurology 59:1275-7. 2002
    ..These deaths may have been unrelated to treatment. The unpredictable course of the disease makes evaluation of the clinical response difficult...
  16. doi request reprint Homozygous W748S mutation in the POLG1 gene in patients with juvenile-onset Alpers syndrome and status epilepticus
    Johanna Uusimaa
    Department of Pediatrics, University of Oulu, Oulu, Finland
    Epilepsia 49:1038-45. 2008
    ..Here we studied the molecular etiology of juvenile-onset AHS manifesting with status epilepticus and liver disease in three teenagers...
  17. doi request reprint Cerebrospinal fluid antibodies to oxidized LDL are increased in Alzheimer's disease
    Jari Kankaanpää
    Department of Neurology, University of Oulu, Oulu, Finland
    Neurobiol Dis 33:467-72. 2009
    ..CSF IgG antibodies to OxLDL were significantly increased in AD patients compared to controls and to patients with frontotemporal lobar degeneration. The role of these antibodies in CSF is unknown and further investigations are needed...
  18. ncbi request reprint Sequence analysis of nuclear genes encoding functionally important complex I subunits in children with encephalomyopathy
    Reetta Hinttala
    Department of Neurology, University of Oulu, Finland
    J Mol Med (Berl) 83:786-94. 2005
    ..We suggest that Arg18Cys in the leading peptide of the TYKY subunit is not solely pathogenic, and that other genetic factors contribute to the disease-causing potential of this mutation...
  19. ncbi request reprint Inhibition of hypoxia-inducible factor (HIF) hydroxylases by citric acid cycle intermediates: possible links between cell metabolism and stabilization of HIF
    Peppi Koivunen
    Collagen Research Unit, Biocenter Oulu, Departments of Medical Biochemistry and Molecular Biology and Neurology, University of Oulu, FIN 90014 Oulu, Finland
    J Biol Chem 282:4524-32. 2007
    ....
  20. ncbi request reprint Molecular epidemiology of childhood mitochondrial encephalomyopathies in a Finnish population: sequence analysis of entire mtDNA of 17 children reveals heteroplasmic mutations in tRNAArg, tRNAGlu, and tRNALeu(UUR) genes
    Johanna Uusimaa
    Department of Departments of Pediatrics, University of Oulu, Oulu, Finland
    Pediatrics 114:443-50. 2004
    ..Seventeen of them were found to have both a defect in the mitochondrial respiratory chain and abnormal ultrastructure of muscle mitochondria, suggesting a clinically probable mitochondrial encephalopathy...
  21. ncbi request reprint Dance/Movement Therapeutic methods in management of dementia
    Laura Hokkanen
    J Am Geriatr Soc 51:576-7. 2003
  22. doi request reprint Dance and movement therapeutic methods in management of dementia: a randomized, controlled study
    Laura Hokkanen
    J Am Geriatr Soc 56:771-2. 2008
  23. doi request reprint Differential metabolic consequences of fumarate hydratase and respiratory chain defects
    Nuno Raimundo
    Program of Molecular Neurology Biomedicum Helsinki, Finland
    Biochim Biophys Acta 1782:287-94. 2008
    ..The lack of cytoplasmic form of FH and the reduced redox environment were typical for all FH-mutant lines, and their role in FH-related tumorigenesis requires further attention...