Kristiina Rajala

Summary

Affiliation: University of Tampere
Country: Finland

Publications

  1. ncbi request reprint Testing of nine different xeno-free culture media for human embryonic stem cell cultures
    Kristiina Rajala
    REGEA, Institute for Regenerative Medicine, University of Tampere, Tampere University Hospital, Tampere, Finland
    Hum Reprod 22:1231-8. 2007
  2. pmc A defined and xeno-free culture method enabling the establishment of clinical-grade human embryonic, induced pluripotent and adipose stem cells
    Kristiina Rajala
    Regea Institute for Regenerative Medicine, University of Tampere, Tampere University Hospital, Tampere, Finland
    PLoS ONE 5:e10246. 2010
  3. pmc Culture conditions affect cardiac differentiation potential of human pluripotent stem cells
    Marisa Ojala
    Institute of Biomedical Technology, University of Tampere, Tampere, Finland
    PLoS ONE 7:e48659. 2012
  4. pmc Monitoring and analysis of dynamic growth of human embryonic stem cells: comparison of automated instrumentation and conventional culturing methods
    Susanna Narkilahti
    REGEA, Institute for Regenerative Medicine, University of Tampere and Tampere University Hospital, 33520 Tampere, Finland
    Biomed Eng Online 6:11. 2007
  5. pmc Toward the defined and xeno-free differentiation of functional human pluripotent stem cell-derived retinal pigment epithelial cells
    Hanna Vaajasaari
    Regea Institute for Regenerative Medicine, University of Tampere, Tampere, Finland
    Mol Vis 17:558-75. 2011
  6. pmc The effect of human and mouse fibroblast feeder cells on cardiac differentiation of human pluripotent stem cells
    Mari Pekkanen-Mattila
    Institute of Biomedical Technology, University of Tampere, Biokatu 12, 33520 Tampere, Finland
    Stem Cells Int 2012:875059. 2012
  7. doi request reprint Comparison of biomaterials and extracellular matrices as a culture platform for multiple, independently derived human embryonic stem cell lines
    Heidi Hakala
    REGEA, Institute for Regenerative Medicine, University of Tampere, Tampere, Finland
    Tissue Eng Part A 15:1775-85. 2009
  8. pmc Cardiac differentiation of pluripotent stem cells
    Kristiina Rajala
    Regea Institute for Regenerative Medicine, University of Tampere, Tampere University Hospital, 33520 Tampere, Finland
    Stem Cells Int 2011:383709. 2011

Collaborators

Detail Information

Publications8

  1. ncbi request reprint Testing of nine different xeno-free culture media for human embryonic stem cell cultures
    Kristiina Rajala
    REGEA, Institute for Regenerative Medicine, University of Tampere, Tampere University Hospital, Tampere, Finland
    Hum Reprod 22:1231-8. 2007
    ..However, currently used culture conditions contain animal-derived components that bear a risk of transmitting animal pathogens and incorporation of non-human immunogenic molecules to hESC...
  2. pmc A defined and xeno-free culture method enabling the establishment of clinical-grade human embryonic, induced pluripotent and adipose stem cells
    Kristiina Rajala
    Regea Institute for Regenerative Medicine, University of Tampere, Tampere University Hospital, Tampere, Finland
    PLoS ONE 5:e10246. 2010
    ..For clinical application of stem cells, the use of completely defined conditions and elimination of all animal-derived materials from the establishment, culture, and differentiation processes is desirable...
  3. pmc Culture conditions affect cardiac differentiation potential of human pluripotent stem cells
    Marisa Ojala
    Institute of Biomedical Technology, University of Tampere, Tampere, Finland
    PLoS ONE 7:e48659. 2012
    ..In conclusion, culture conditions have a major impact on the propensity of the hPSCs to differentiate into a cardiac lineage...
  4. pmc Monitoring and analysis of dynamic growth of human embryonic stem cells: comparison of automated instrumentation and conventional culturing methods
    Susanna Narkilahti
    REGEA, Institute for Regenerative Medicine, University of Tampere and Tampere University Hospital, 33520 Tampere, Finland
    Biomed Eng Online 6:11. 2007
    ..Continuous monitoring of living cell cultures can reveal more information and is faster than using laborious traditional methods such as microscopic evaluation, immunohistochemistry and flow cytometry...
  5. pmc Toward the defined and xeno-free differentiation of functional human pluripotent stem cell-derived retinal pigment epithelial cells
    Hanna Vaajasaari
    Regea Institute for Regenerative Medicine, University of Tampere, Tampere, Finland
    Mol Vis 17:558-75. 2011
    ....
  6. pmc The effect of human and mouse fibroblast feeder cells on cardiac differentiation of human pluripotent stem cells
    Mari Pekkanen-Mattila
    Institute of Biomedical Technology, University of Tampere, Biokatu 12, 33520 Tampere, Finland
    Stem Cells Int 2012:875059. 2012
    ..In conclusion, the cells behaved differently whether cultured on hFF or MEF feeders. However, the influence of the feeder cells on differentiation was less than the difference observed between the cell lines...
  7. doi request reprint Comparison of biomaterials and extracellular matrices as a culture platform for multiple, independently derived human embryonic stem cell lines
    Heidi Hakala
    REGEA, Institute for Regenerative Medicine, University of Tampere, Tampere, Finland
    Tissue Eng Part A 15:1775-85. 2009
    ..A long-term, feeder cell-free culture system was successful on Matrigel in combination with mTeSR1 culture medium, but a xeno-free, fully defined, and reproducible feeder cell-free hESC culture method still remains to be developed...
  8. pmc Cardiac differentiation of pluripotent stem cells
    Kristiina Rajala
    Regea Institute for Regenerative Medicine, University of Tampere, Tampere University Hospital, 33520 Tampere, Finland
    Stem Cells Int 2011:383709. 2011
    ..In this paper, we will discuss the strategies for the generation of cardiomyocytes from pluripotent stem cells and their characteristics, as well as highlight some applications for the cells...