Oscar Puig

Summary

Affiliation: University of Helsinki
Country: Finland

Publications

  1. pmc The U1 snRNP-associated factor Luc7p affects 5' splice site selection in yeast and human
    Oscar Puig
    European Molecular Biology Laboratory, Meyerhofstrasse, 1, 69117 Heidelberg, Germany
    Nucleic Acids Res 35:5874-85. 2007
  2. pmc The splicing regulator TIA-1 interacts with U1-C to promote U1 snRNP recruitment to 5' splice sites
    Patrik Förch
    Gene Expression Programme, European Molecular Biology Laboratory, Meyerhofstrasse 1, D 69117 Heidelberg, Germany
    EMBO J 21:6882-92. 2002
  3. ncbi request reprint Nutrient availability and growth: regulation of insulin signaling by dFOXO/FOXO1
    Oscar Puig
    Institute of Biotechnology, University of Helsinki, Helsinki, Finland
    Cell Cycle 5:503-5. 2006
  4. pmc Control of cell number by Drosophila FOXO: downstream and feedback regulation of the insulin receptor pathway
    Oscar Puig
    Howard Hughes Medical Institute and Department of Molecular and Cell Biology, University of California, Berkeley, California 94720, USA
    Genes Dev 17:2006-20. 2003
  5. doi request reprint dFOXO regulates transcription of a Drosophila acid lipase
    Terhi Vihervaara
    Institute of Biotechnology, University of Helsinki, Viikinkaari 9, 00014 Helsinki, Finland
    J Mol Biol 376:1215-23. 2008
  6. ncbi request reprint High-resolution dynamics of the transcriptional response to nutrition in Drosophila: a key role for dFOXO
    Boris Gershman
    Division of Biology and Medicine, Brown University, Providence, Rhode Island 02912, USA
    Physiol Genomics 29:24-34. 2007
  7. pmc IRES-mediated functional coupling of transcription and translation amplifies insulin receptor feedback
    Michael T Marr
    Howard Hughes Medical Institute, Department of Molecular and Cell Biology, University of California at Berkeley, Berkeley, California 94720, USA
    Genes Dev 21:175-83. 2007
  8. ncbi request reprint Characterization of the Drosophila insulin receptor promoter
    Sergio Casas-Tinto
    Institute of Biotechnology, University of Helsinki, Viikinkaari 9, FIN 00014, Finland
    Biochim Biophys Acta 1769:236-43. 2007
  9. pmc Foxo and Fos regulate the decision between cell death and survival in response to UV irradiation
    Xi Luo
    Department of Biology, University of Rochester, Rochester, NY 14627, USA
    EMBO J 26:380-90. 2007
  10. pmc Transcriptional feedback control of insulin receptor by dFOXO/FOXO1
    Oscar Puig
    Howard Hughes Medical Institute and Department of Molecular and Cell Biology, University of California, Berkeley, California 94720, USA
    Genes Dev 19:2435-46. 2005

Collaborators

Detail Information

Publications11

  1. pmc The U1 snRNP-associated factor Luc7p affects 5' splice site selection in yeast and human
    Oscar Puig
    European Molecular Biology Laboratory, Meyerhofstrasse, 1, 69117 Heidelberg, Germany
    Nucleic Acids Res 35:5874-85. 2007
    ..Taken together, our data suggest that the formation of a wide network of protein-RNA interactions around the 5' splice site by U1 snRNP-associated factors contributes to alternative splicing regulation...
  2. pmc The splicing regulator TIA-1 interacts with U1-C to promote U1 snRNP recruitment to 5' splice sites
    Patrik Förch
    Gene Expression Programme, European Molecular Biology Laboratory, Meyerhofstrasse 1, D 69117 Heidelberg, Germany
    EMBO J 21:6882-92. 2002
    ....
  3. ncbi request reprint Nutrient availability and growth: regulation of insulin signaling by dFOXO/FOXO1
    Oscar Puig
    Institute of Biotechnology, University of Helsinki, Helsinki, Finland
    Cell Cycle 5:503-5. 2006
    ..Recent studies with the fruit fly Drosophila melanogaster have provided new insights into the regulatory circuitry that controls both growth and gene expression in response to nutrient availability...
  4. pmc Control of cell number by Drosophila FOXO: downstream and feedback regulation of the insulin receptor pathway
    Oscar Puig
    Howard Hughes Medical Institute and Department of Molecular and Cell Biology, University of California, Berkeley, California 94720, USA
    Genes Dev 17:2006-20. 2003
    ..Our results establish dFOXO as a key transcriptional regulator of the insulin pathway that modulates growth and proliferation...
  5. doi request reprint dFOXO regulates transcription of a Drosophila acid lipase
    Terhi Vihervaara
    Institute of Biotechnology, University of Helsinki, Viikinkaari 9, 00014 Helsinki, Finland
    J Mol Biol 376:1215-23. 2008
    ..Our results support a model where dFOXO acts as a key modulator of lipid metabolism by insulin signaling and integrates insulin responses to glucose and lipid homeostasis...
  6. ncbi request reprint High-resolution dynamics of the transcriptional response to nutrition in Drosophila: a key role for dFOXO
    Boris Gershman
    Division of Biology and Medicine, Brown University, Providence, Rhode Island 02912, USA
    Physiol Genomics 29:24-34. 2007
    ....
  7. pmc IRES-mediated functional coupling of transcription and translation amplifies insulin receptor feedback
    Michael T Marr
    Howard Hughes Medical Institute, Department of Molecular and Cell Biology, University of California at Berkeley, Berkeley, California 94720, USA
    Genes Dev 21:175-83. 2007
    ....
  8. ncbi request reprint Characterization of the Drosophila insulin receptor promoter
    Sergio Casas-Tinto
    Institute of Biotechnology, University of Helsinki, Viikinkaari 9, FIN 00014, Finland
    Biochim Biophys Acta 1769:236-43. 2007
    ..Our results indicate that dInR expression in Drosophila displays an intricate pattern of regulation that assures an adequate control of growth, development and metabolism...
  9. pmc Foxo and Fos regulate the decision between cell death and survival in response to UV irradiation
    Xi Luo
    Department of Biology, University of Rochester, Rochester, NY 14627, USA
    EMBO J 26:380-90. 2007
    ..These data suggest that integrating stress and survival signals through Foxo drives the decision between cell death and repair of damaged cells in vivo...
  10. pmc Transcriptional feedback control of insulin receptor by dFOXO/FOXO1
    Oscar Puig
    Howard Hughes Medical Institute and Department of Molecular and Cell Biology, University of California, Berkeley, California 94720, USA
    Genes Dev 19:2435-46. 2005
    ..Our results reveal a key feedback control mechanism for dFOXO/FOXO1 in regulating metabolism and insulin signaling...
  11. pmc FOXO-regulated transcription restricts overgrowth of Tsc mutant organs
    Kieran F Harvey
    Cell Growth and Proliferation Laboratory, Peter MacCallum Cancer Centre, East Melbourne, Victoria 3002, Australia
    J Cell Biol 180:691-6. 2008
    ..Analogous transcriptional changes are observed in mammalian cells, which implies that FOXO attenuates TOR-driven growth in diverse species...