U Pirvola

Summary

Affiliation: University of Helsinki
Country: Finland

Publications

  1. ncbi request reprint Rescue of hearing, auditory hair cells, and neurons by CEP-1347/KT7515, an inhibitor of c-Jun N-terminal kinase activation
    U Pirvola
    Institute of Biotechnology, University of Helsinki, Helsinki 00014, Finland
    J Neurosci 20:43-50. 2000
  2. ncbi request reprint Guinea pig auditory neurons are protected by glial cell line-derived growth factor from degeneration after noise trauma
    J Ylikoski
    Department of ORL, University of Helsinki, Finland
    Hear Res 124:17-26. 1998
  3. ncbi request reprint Apoptosis in auditory brainstem neurons after a severe noise trauma of the organ of Corti: intracochlear GDNF treatment reduces the number of apoptotic cells
    A A Aarnisalo
    Department of Otolaryngology, University of Helsinki, Finland
    ORL J Otorhinolaryngol Relat Spec 62:330-4. 2000
  4. doi request reprint Hyperbaric oxygen therapy seems to enhance recovery from acute acoustic trauma
    J Ylikoski
    Helsinki Ear Institute and Department of Otolaryngology, University of Helsinki, Helsinki, Finland
    Acta Otolaryngol 128:1110-5. 2008
  5. ncbi request reprint FGF/FGFR-2(IIIb) signaling is essential for inner ear morphogenesis
    U Pirvola
    Institute of Biotechnology and Department of Otorhinolaryngology, University of Helsinki, 00014 Helsinki, Finland
    J Neurosci 20:6125-34. 2000

Detail Information

Publications5

  1. ncbi request reprint Rescue of hearing, auditory hair cells, and neurons by CEP-1347/KT7515, an inhibitor of c-Jun N-terminal kinase activation
    U Pirvola
    Institute of Biotechnology, University of Helsinki, Helsinki 00014, Finland
    J Neurosci 20:43-50. 2000
    ..These results suggest that therapeutic intervention in the JNK signaling cascade, possibly by using CEP-1347, may offer opportunities to treat inner ear injuries...
  2. ncbi request reprint Guinea pig auditory neurons are protected by glial cell line-derived growth factor from degeneration after noise trauma
    J Ylikoski
    Department of ORL, University of Helsinki, Finland
    Hear Res 124:17-26. 1998
    ....
  3. ncbi request reprint Apoptosis in auditory brainstem neurons after a severe noise trauma of the organ of Corti: intracochlear GDNF treatment reduces the number of apoptotic cells
    A A Aarnisalo
    Department of Otolaryngology, University of Helsinki, Finland
    ORL J Otorhinolaryngol Relat Spec 62:330-4. 2000
    ..This can be prevented partially by rescuing primary cochlear neurons from degeneration with local GDNF treatment...
  4. doi request reprint Hyperbaric oxygen therapy seems to enhance recovery from acute acoustic trauma
    J Ylikoski
    Helsinki Ear Institute and Department of Otolaryngology, University of Helsinki, Helsinki, Finland
    Acta Otolaryngol 128:1110-5. 2008
    ..HBOT can be valuable adjuvant therapy for patients with acute acoustic trauma (AAT)...
  5. ncbi request reprint FGF/FGFR-2(IIIb) signaling is essential for inner ear morphogenesis
    U Pirvola
    Institute of Biotechnology and Department of Otorhinolaryngology, University of Helsinki, 00014 Helsinki, Finland
    J Neurosci 20:6125-34. 2000
    ..Our findings provide genetic evidence that signaling by FGFR-2(IIIb) is critical for the morphological development of the inner ear...