U Pirvola

Summary

Affiliation: University of Helsinki
Country: Finland

Publications

  1. ncbi Rescue of hearing, auditory hair cells, and neurons by CEP-1347/KT7515, an inhibitor of c-Jun N-terminal kinase activation
    U Pirvola
    Institute of Biotechnology, University of Helsinki, Helsinki 00014, Finland
    J Neurosci 20:43-50. 2000
  2. ncbi Guinea pig auditory neurons are protected by glial cell line-derived growth factor from degeneration after noise trauma
    J Ylikoski
    Department of ORL, University of Helsinki, Finland
    Hear Res 124:17-26. 1998
  3. ncbi Apoptosis in auditory brainstem neurons after a severe noise trauma of the organ of Corti: intracochlear GDNF treatment reduces the number of apoptotic cells
    A A Aarnisalo
    Department of Otolaryngology, University of Helsinki, Finland
    ORL J Otorhinolaryngol Relat Spec 62:330-4. 2000
  4. ncbi Hyperbaric oxygen therapy seems to enhance recovery from acute acoustic trauma
    J Ylikoski
    Helsinki Ear Institute and Department of Otolaryngology, University of Helsinki, Helsinki, Finland
    Acta Otolaryngol 128:1110-5. 2008
  5. ncbi FGF/FGFR-2(IIIb) signaling is essential for inner ear morphogenesis
    U Pirvola
    Institute of Biotechnology and Department of Otorhinolaryngology, University of Helsinki, 00014 Helsinki, Finland
    J Neurosci 20:6125-34. 2000

Detail Information

Publications5

  1. ncbi Rescue of hearing, auditory hair cells, and neurons by CEP-1347/KT7515, an inhibitor of c-Jun N-terminal kinase activation
    U Pirvola
    Institute of Biotechnology, University of Helsinki, Helsinki 00014, Finland
    J Neurosci 20:43-50. 2000
    ..These results suggest that therapeutic intervention in the JNK signaling cascade, possibly by using CEP-1347, may offer opportunities to treat inner ear injuries...
  2. ncbi Guinea pig auditory neurons are protected by glial cell line-derived growth factor from degeneration after noise trauma
    J Ylikoski
    Department of ORL, University of Helsinki, Finland
    Hear Res 124:17-26. 1998
    ....
  3. ncbi Apoptosis in auditory brainstem neurons after a severe noise trauma of the organ of Corti: intracochlear GDNF treatment reduces the number of apoptotic cells
    A A Aarnisalo
    Department of Otolaryngology, University of Helsinki, Finland
    ORL J Otorhinolaryngol Relat Spec 62:330-4. 2000
    ..This can be prevented partially by rescuing primary cochlear neurons from degeneration with local GDNF treatment...
  4. ncbi Hyperbaric oxygen therapy seems to enhance recovery from acute acoustic trauma
    J Ylikoski
    Helsinki Ear Institute and Department of Otolaryngology, University of Helsinki, Helsinki, Finland
    Acta Otolaryngol 128:1110-5. 2008
    ..HBOT can be valuable adjuvant therapy for patients with acute acoustic trauma (AAT)...
  5. ncbi FGF/FGFR-2(IIIb) signaling is essential for inner ear morphogenesis
    U Pirvola
    Institute of Biotechnology and Department of Otorhinolaryngology, University of Helsinki, 00014 Helsinki, Finland
    J Neurosci 20:6125-34. 2000
    ..Our findings provide genetic evidence that signaling by FGFR-2(IIIb) is critical for the morphological development of the inner ear...