Antti Perheentupa

Summary

Affiliation: University of Turku
Country: Finland

Publications

  1. pmc Serum HE4 concentration differentiates malignant ovarian tumours from ovarian endometriotic cysts
    K Huhtinen
    Department of Physiology, Institute of Biomedicine, University of Turku, Turku, Finland
    Br J Cancer 100:1315-9. 2009
  2. doi A cohort effect on serum testosterone levels in Finnish men
    A Perheentupa
    Department of Physiology, Institute of Biomedicine, University of Turku, Kiinamyllynkatu 10, FI 20520 Turku, Finland
    Eur J Endocrinol 168:227-33. 2013
  3. ncbi Does the andropause exist?
    Antti Perheentupa
    Department of Physiology, University of Turku, Finland
    Nat Clin Pract Endocrinol Metab 3:670-1. 2007
  4. doi Endogenous testosterone and brachial artery endothelial function in middle-aged men with symptoms of late-onset hypogonadism
    Juuso I Mäkinen
    Department of Clinical Physiology, University of Turku, Turku, Finland
    Aging Male 14:237-42. 2011
  5. ncbi Late-onset hypogonadism in men. Experience from the Turku Male Ageing Study (TuMAS)
    Ilpo Huhtaniemi
    Department of Physiology, University of Turku, Turku, Finland
    Hormones (Athens) 7:36-45. 2008
  6. ncbi Endogenous testosterone and serum lipids in middle-aged men
    Juuso I Mäkinen
    Department of Clinical Physiology, University of Turku, FIN 20520 Turku, Finland
    Atherosclerosis 197:688-93. 2008
  7. doi Smoking and low serum testosterone associates with high concentration of oxidized LDL
    Meri S Linna
    Department of Health and Exercise, Paavo Nurmi Center, University of Turku, Turku, Finland
    Ann Med 40:634-40. 2008
  8. ncbi Sexual symptoms in aging men indicate poor life satisfaction and increased health service consumption
    Juuso I Mäkinen
    Department of Clinical Physiology, University of Turku, Turku, Finland
    Urology 70:1194-9. 2007
  9. pmc Endometrial and endometriotic concentrations of estrone and estradiol are determined by local metabolism rather than circulating levels
    Kaisa Huhtinen
    University of Turku, 20014 Turku, Finland
    J Clin Endocrinol Metab 97:4228-35. 2012
  10. ncbi Increased carotid atherosclerosis in andropausal middle-aged men
    Juuso Mäkinen
    Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland
    J Am Coll Cardiol 45:1603-8. 2005

Collaborators

Detail Information

Publications26

  1. pmc Serum HE4 concentration differentiates malignant ovarian tumours from ovarian endometriotic cysts
    K Huhtinen
    Department of Physiology, Institute of Biomedicine, University of Turku, Turku, Finland
    Br J Cancer 100:1315-9. 2009
    ..Taken together, measuring both HE4 and CA125 serum concentrations increases the accuracy of ovarian cancer diagnosis and provides valuable information to discriminate ovarian tumours from ovarian endometriotic cysts...
  2. doi A cohort effect on serum testosterone levels in Finnish men
    A Perheentupa
    Department of Physiology, Institute of Biomedicine, University of Turku, Kiinamyllynkatu 10, FI 20520 Turku, Finland
    Eur J Endocrinol 168:227-33. 2013
    ..e. semen quality, incidence of cryptorchidism and testicular cancer); thus, we expected no significant cohort-dependent decrease in serum testosterone...
  3. ncbi Does the andropause exist?
    Antti Perheentupa
    Department of Physiology, University of Turku, Finland
    Nat Clin Pract Endocrinol Metab 3:670-1. 2007
  4. doi Endogenous testosterone and brachial artery endothelial function in middle-aged men with symptoms of late-onset hypogonadism
    Juuso I Mäkinen
    Department of Clinical Physiology, University of Turku, Turku, Finland
    Aging Male 14:237-42. 2011
    ..In middle-aged to elderly men, there is an inverse correlation between serum testosterone and brachial FMD. These data suggest that testosterone may have an adverse effect on systemic endothelial function...
  5. ncbi Late-onset hypogonadism in men. Experience from the Turku Male Ageing Study (TuMAS)
    Ilpo Huhtaniemi
    Department of Physiology, University of Turku, Turku, Finland
    Hormones (Athens) 7:36-45. 2008
    ..This review summarises the recent key findings in this study, with special reference to the correlation of androgen levels with sexual symptoms and cardiovascular risk factors...
  6. ncbi Endogenous testosterone and serum lipids in middle-aged men
    Juuso I Mäkinen
    Department of Clinical Physiology, University of Turku, FIN 20520 Turku, Finland
    Atherosclerosis 197:688-93. 2008
    ..The role of decreasing testosterone levels influencing lipid metabolism in aging men is not well established...
  7. doi Smoking and low serum testosterone associates with high concentration of oxidized LDL
    Meri S Linna
    Department of Health and Exercise, Paavo Nurmi Center, University of Turku, Turku, Finland
    Ann Med 40:634-40. 2008
    ..The interplay between smoking, oxidized low-density lipoprotein cholesterol (ox-LDL) and gonadal hormones has been scarcely investigated...
  8. ncbi Sexual symptoms in aging men indicate poor life satisfaction and increased health service consumption
    Juuso I Mäkinen
    Department of Clinical Physiology, University of Turku, Turku, Finland
    Urology 70:1194-9. 2007
    ..The deterioration of sexual, physical, and mental performance in aging men has been used to measure the clinical manifestations of androgen decrement. However, their prevalence and relation to coexisting morbidities are unknown...
  9. pmc Endometrial and endometriotic concentrations of estrone and estradiol are determined by local metabolism rather than circulating levels
    Kaisa Huhtinen
    University of Turku, 20014 Turku, Finland
    J Clin Endocrinol Metab 97:4228-35. 2012
    ..However, tissue estrogen concentrations within the endometrium and different types of endometriosis lesions have not been described...
  10. ncbi Increased carotid atherosclerosis in andropausal middle-aged men
    Juuso Mäkinen
    Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland
    J Am Coll Cardiol 45:1603-8. 2005
    ..This study examined the association between carotid artery intima-media thickness (IMT), serum sex hormone levels, and andropausal symptoms in middle-aged men...
  11. ncbi [Primary dysmenorrhea painful menstruation]
    Antti Perheentupa
    TYKS n naistenklinikka, ja Turun yliopisto biolääketieteen laitos, fysiologia, Turku
    Duodecim 121:1411-8. 2005
  12. ncbi [Birth control during lactation and breast feeding]
    Antti Perheentupa
    TYKS n naistenklinikka, Turku
    Duodecim 120:1467-73, 1499. 2004
  13. doi Estrogen biosynthesis and signaling in endometriosis
    Kaisa Huhtinen
    Department of Physiology, Institute of Biomedicine, University of Turku, 20014 Turku, Finland
    Mol Cell Endocrinol 358:146-54. 2012
    ..Further studies are still needed to define the possible differences in steroid metabolism in different types of endometriotic lesions...
  14. doi Intra-tissue steroid profiling indicates differential progesterone and testosterone metabolism in the endometrium and endometriosis lesions
    Kaisa Huhtinen
    Department of Physiology K H, T S H, D L, M S, M A, A P, M P, Institute of Biomedicine, University of Turku, 20014 Turku, Finland Department of Obstetrics and Gynecology K H, P S, A P, University of Turku, 20014 Turku, Finland School of Pharmacy, University of Eastern Finland P K R, M R H, S A, 70211 Kuopio, Finland ANZAC Research Institute R D, D J H, Concord Hospital, University of Sydney, 2139, Australia Institute for Molecular Medicine Finland D L, T A, University of Helsinki, 00014 Helsinki, Finland Department of Pathology H K, Institute of Biomedicine, University of Turku, 20014 Turku, Finland Turku Center for Disease Modeling M P, University of Turku, 20014 Turku, Finland and Institute of Medicine M P, The Sahlgrenska Academy
    J Clin Endocrinol Metab 99:E2188-97. 2014
    ..However, their concentrations are only superficially known in the endometrium and endometriosis lesions...
  15. ncbi Transdermal estradiol treatment suppresses serum gonadotropins during lactation without transfer into breast milk
    Antti Perheentupa
    Department of Obstetrics and Gynecology and Department of Physiology, University of Turku, Turku, Finland
    Fertil Steril 82:903-7. 2004
    ..To determine which dose of transdermal E(2) could be administered to breastfeeding women without significant transfer into breast milk...
  16. doi Aging of the human ovary and testis
    Antti Perheentupa
    Department of Obstetrics and Gynaecology, University of Turku, Kiinamyllynkatu 10, 20520 Turku, Finland
    Mol Cell Endocrinol 299:2-13. 2009
    ..The clinically important aspect of testicular aging entails the decline of androgen production in aging men...
  17. doi Ovarian endometriosis signatures established through discovery and directed mass spectrometry analysis
    Anni P Vehmas
    Turku Centre for Biotechnology, Department of Physiology, Institute of Biomedicine, Department of Mathematics and Statistics, and Turku Center for Disease Modeling, University of Turku, Turku, Finland
    J Proteome Res 13:4983-94. 2014
    ..This study provides the most comprehensive molecular description of ovarian endometriosis to date and researchers with new molecular methods and tools for high throughput patient screening using the SRM assays. ..
  18. doi Resampling reveals sample-level differential expression in clinical genome-wide studies
    Jukka Hiissa
    Biomathematics Research Group, Department of Mathematics, University of Turku, Turku, Finland
    OMICS 13:381-96. 2009
    ..The generic procedure should benefit also other global profiling experiments such as those based on mass spectrometry-based proteomic assays...
  19. doi Serum HE4 Profile During Primary Chemotherapy of Epithelial Ovarian Cancer
    Johanna Hynninen
    Department of Obstetrics and Gynaecology, Turku University Hospital, University of Turku, Turku, Finland
    Int J Gynecol Cancer 21:1573-8. 2011
    ..The objective of the present study was to determine the value of HE4 for monitoring the response to primary therapy in patients with advanced disease...
  20. doi Serum concentrations of HE4 change little during in vitro fertilization
    Marianne Hallamaa
    Department of Obstetrics and Gynecology, Turku University Hospital and University of Turku, Turku, Finland
    Acta Obstet Gynecol Scand 93:640-6. 2014
    ..Findings were compared with serum concentrations of cancer antigen 125 (CA125), currently the most commonly used marker for ovarian cancer...
  21. pmc Novel hydroxysteroid (17beta) dehydrogenase 1 inhibitors reverse estrogen-induced endometrial hyperplasia in transgenic mice
    Taija Saloniemi
    Department of Physiology, University of Turku, and the Department of Obstetrics and Gynecology, Turku University Central Hospital, Kiinamyllynkatu 10, FIN 20014 Turku, Finland
    Am J Pathol 176:1443-51. 2010
    ..Therefore, HSD17B1 is a promising new therapeutic target in the management of estrogen-dependent endometrial diseases...
  22. ncbi Male contraception--quo vadis?
    Antti Perheentupa
    Departments of Physiology and Obstetrics and Gynecology, University of Turku, Finland
    Acta Obstet Gynecol Scand 83:131-7. 2004
    ....
  23. ncbi Ovarian age-related responsiveness to human chorionic gonadotropin in women with polycystic ovary syndrome
    Terhi Piltonen
    Department of Obstetrics and Gynecology, Oulu University Hospital, Finland
    J Clin Endocrinol Metab 89:3769-75. 2004
    ....
  24. doi Male hormonal contraception: a double-blind, placebo-controlled study
    Ellen Mommers
    Global Clinical Development Department, Organon, part of Schering Plough, Oss, The Netherlands
    J Clin Endocrinol Metab 93:2572-80. 2008
    ..This is the first large placebo-controlled study for male hormonal contraception...
  25. ncbi Serum anti-Müllerian hormone levels remain high until late reproductive age and decrease during metformin therapy in women with polycystic ovary syndrome
    Terhi Piltonen
    Department of Obstetrics and Gynecology, Oulu University Hospital, Oulu, Finland
    Hum Reprod 20:1820-6. 2005
    ..Moreover, the possible effect of metformin on serum AMH levels and the relationship to follicle count and volume were studied...
  26. ncbi Effect of progestin-only pill on pituitary-ovarian axis activity during lactation
    Antti Perheentupa
    Medical Research Council Human Reproductive Sciences Unit, Centre for Reproductive Biology, The University of Edinburgh Chancellor s Building, 49 Little France Crescent, Old Dalkeith Road, Edinburgh EH16 4SB, UK
    Contraception 67:467-71. 2003
    ..Thus, the contraceptive effect of POP is likely mediated through local actions at the endometrium and cervix in a manner similar to that in menstruating women...