Research Topics
| E PekkonenSummaryAffiliation: University of Helsinki Country: Finland Publications
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Detail Information
Publications
Impaired preconscious auditory processing and cognitive functions in Alzheimer's diseaseE Pekkonen
Department of Neurology, Helsinki University Central Hospital, Finland
Clin Neurophysiol 110:1942-7. 1999..To investigate whether auditory processing correlates with the impairment of the higher cortical functions...
Mismatch negativity in aging and in Alzheimer's and Parkinson's diseasesE Pekkonen
Department of Neurology, Helsinki University Central Hospital, Finland
Audiol Neurootol 5:216-24. 2000..The MMN appears to offer an objective tool for studying auditory processing and memory trace decay in different neurological disorders...
Effects of haloperidol on selective attention: a combined whole-head MEG and high-resolution EEG studyS Kahkonen
BioMag Laboratory, Medical Engineering Centre, Helsinki University Central Hospital, Helsinki, Finland
Neuropsychopharmacology 25:498-504. 2001..Taken together, haloperidol seemed to induce functional changes in neural networks accounting for both selective and involuntary attention, suggesting modulation of these functions by dopamine D2 receptors...
Replicability of MEG and EEG measures of the auditory N1/N1m-responseJ Virtanen
Department of Psychology, University of Helsinki, Helsinki University Central Hospital, Finland
Electroencephalogr Clin Neurophysiol 108:291-8. 1998..The results suggest that both MEG and EEG can be used for investigating the simultaneous activity of the left and right auditory cortices independently, MEG being superior in certain experimental setups...
Preserved stimulus deviance detection in Alzheimer's diseaseE Pekkonen
Department of Neurology, University of Helsinki, and Medical Engineering Centre, Helsinki University Central Hospital, Finland
Neuroreport 12:1649-52. 2001..This suggests that although MMNm is delayed in the left hemisphere, the automatic discrimination to duration change in the auditory cortex is not attenuated in the early stages of AD...
Scopolamine reduces the P35m and P60m deflections of the human somatosensory evoked magnetic fieldsJ Huttunen
BioMag Laboratory, Medical Engineering Centre, Helsinki University Central Hospital, Finland
Neuroreport 12:619-23. 2001..Relative membrane hyperpolarization of pyramidal neurons due to scopolamine (caused by blocking an ACh-induced tonic depolarization) is discussed as a possible mechanism underlying the observed effects...
No evidence for dependence of early cortical auditory processing on dopamine D(2)-receptor modulation: a whole-head magnetoencephalographic studyS Kahkonen
BioMag Laboratory, Medical Engineering Centre, Helsinki University Central Hospital, P O Box 340, FIN 00029 Helsinki, Finland
Psychiatry Res 107:117-23. 2001..The dipole moments and source locations of the responses were not significantly influenced by haloperidol. These results suggest that dopamine D(2) receptors are not involved in the early phases of auditory cortical processing...
Auditory sensory memory and the cholinergic system: implications for Alzheimer's diseaseE Pekkonen
Department of Neurology, Helsinki University Central Hospital, Finland
Neuroimage 14:376-82. 2001..Auditory evoked potentials might be suitable to monitor cholinergic activity in AD...
