Research Topics
| Markku PartinenSummaryAffiliation: University of Helsinki Country: Finland Publications
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Detail Information
Publications
Increased incidence and clinical picture of childhood narcolepsy following the 2009 H1N1 pandemic vaccination campaign in FinlandMarkku Partinen
Helsinki Sleep Clinic, Vitalmed Research Centre, Helsinki, Finland
PLoS ONE 7:e33723. 2012..Therefore, we carried out a systematic analysis of the incidence of narcolepsy in Finland between the years 2002-2010...
The impacts of nitrous oxide gas on sleep quality during alcohol withdrawalTuuli Lahti
Department of Mental Health and Substance Abuse Services, National Institute for Health and Welfare, Helsinki, Finland
BMC Res Notes 4:108. 2011..abstract:..
Challenging issues: sleep-wake, augmentation and quality of lifeMarkku Partinen
Skogby Sleep Clinic, Rinnekoti Research Centre, FIN 02980 Espoo Finland
Sleep Med 8:S19-24. 2007..However, augmentation can be controlled by using the lowest possible doses of nonergoline dopamine agonists or by using opioids, gabapentin or anti-epileptics...
Cognitive-behaviorally-oriented group rehabilitation of adults with ADHD: results of a 6-month follow-upAnita Salakari
Rinnekoti Research Centre, Finland
J Atten Disord 13:516-23. 2010..However, studies about long-term treatment effects are scanty. The authors study effects of cognitive-behaviorally-oriented group rehabilitation during a 6-month follow-up...
Attenuation of vagal recovery during sleep and reduction of cortisol/melatonin ratio in late afternoon associate with prolonged daytime sleepiness among media workers with irregular shift workHarri Lindholm
Finnish Institute of Occupational Health, Centre of Excellence of Health and Work Ability, Helsinki, Finland
Am J Ind Med 55:643-9. 2012..Media work is characterized by information flow, deadlines, and 24/7 alertness. Good recovery prevents stress-related disorders...
Longitudinal study on poor sleep and life dissatisfaction in a nationwide cohort of twinsTiina Paunio
Department of Molecular Medicine, National Public Health Institute, Helsinki, Finland
Am J Epidemiol 169:206-13. 2009..21 for men and 0.27 for women in a multivariate genetic model. This finding is consistent with the hypothesis that poor sleep may have direct effects on the brain, emotions, and mood...
A dose-ranging study of pramipexole for the symptomatic treatment of restless legs syndrome: polysomnographic evaluation of periodic leg movements and sleep disturbanceLeni Jama
Skogby Sleep Clinic, Rinnekoti Research Centre, Kumputie 1, FI 02980 Espoo, Finland
Sleep Med 10:630-6. 2009..To evaluate, both polysomnographically and by subjective scales, the efficacy and safety profile of pramipexole for restless legs syndrome (RLS) via a 3-week, double-blind, placebo-controlled, parallel-group, dose-ranging study...
Open-label study of the long-term efficacy and safety of pramipexole in patients with Restless Legs Syndrome (extension of the PRELUDE study)Markku Partinen
Skogby Sleep Clinic, Rinnekoti Research Centre, Kumputie 1, FI 02980 Espoo, Finland
Sleep Med 9:537-41. 2008..To demonstrate the long-term efficacy and safety of pramipexole for Restless Legs Syndrome (RLS) using physician and patient RLS ratings, along with subjective assays of sleep parameters, in a 26-week, open-label trial...
Associations of reported bruxism with insomnia and insufficient sleep symptoms among media personnel with or without irregular shift workKristiina Ahlberg
Institute of Dentistry, University of Helsinki, Helsinki, Finland
Head Face Med 4:4. 2008....
High job control enhances vagal recovery in media workHarri Lindholm
Centre of Expertise for Health and Work Ability, Finnish Institute of Occupational Health, Helsinki, Finland
Occup Med (Lond) 59:570-3. 2009..Heart rate variability (HRV) has been widely used to monitor sympathovagal balance. Autonomic imbalance may play an additive role in the development of cardiovascular diseases...
AS03 adjuvanted AH1N1 vaccine associated with an abrupt increase in the incidence of childhood narcolepsy in FinlandHanna Nohynek
Department of Vaccines and Immune Protection, National Institute for Health and Welfare, Helsinki, Finland
PLoS ONE 7:e33536. 2012..A sudden increase in childhood narcolepsy was observed in Finland soon after pandemic influenza epidemic and vaccination with ASO3-adjuvanted Pandemrix. No increase was observed in other age groups...
Heritability and mortality risk of insomnia-related symptoms: a genetic epidemiologic study in a population-based twin cohortChrister Hublin
Finnish Institute of Occupational Health, Helsinki, Finland
Sleep 34:957-64. 2011..Our aim was to estimate heritability in phenotypic insomnia and the association between insomnia and mortality...
Short cognitive behavioral therapy and cognitive training for adults with ADHD - a randomized controlled pilot studyMaarit Virta
Rinnekoti Research Centre, Espoo, Finland
Neuropsychiatr Dis Treat 6:443-53. 2010..These preliminary results warrant further studies with more participants and with more elaborate cognitive testing...
Shift-work and cardiovascular disease: a population-based 22-year follow-up studyChrister Hublin
Research Center, Finnish Institute of Occupational Health, Helsinki, Finland
Eur J Epidemiol 25:315-23. 2010..Within twin pairs, no association between shift work and outcome was observed. Our results do not support an association between shift-work and cardiovascular morbidity...
Sleep and mortality: a population-based 22-year follow-up studyChrister Hublin
Research Center, Finnish Institute of Occupational Health, Helsinki, Finland
Sleep 30:1245-53. 2007..Long and short sleep have been associated with increased mortality. We assessed mortality and 3 aspects of sleep behavior in a large cohort with 22-year follow-up...
Efficacy and safety of pramipexole in idiopathic restless legs syndrome: a polysomnographic dose-finding study--the PRELUDE studyMarkku Partinen
Skogby Sleep Clinic, Rinnekoti Research Centre, Kumputie 3, FI 02980 Espoo, Finland
Sleep Med 7:407-17. 2006..To evaluate the effects of pramipexole (0.125-0.75 mg/d) on polysomnographic (PSG) measures and patient and clinician ratings of restless legs syndrome (RLS)...
A systematic evaluation of factors associated with nocturia--the population-based FINNO studyKari A O Tikkinen
Clinical Research Institute HUCH Ltd Tutkijatilat H3011, Haartmaninkatu 4, Helsinki, Finland
Am J Epidemiol 170:361-8. 2009..Although several correlates were identified, none accounted for a substantial proportion of the population burden, highlighting the multifactorial etiology of nocturia...
Radiofrequency surgery of the soft palate in the treatment of mild obstructive sleep apnea is not effective as a single-stage procedure: A randomized single-blinded placebo-controlled trialLeif J J Bäck
Department of Otorhinolaryngology, Finland
Laryngoscope 119:1621-7. 2009..Due to its minimally invasive character, it has received attention in the management of mild obstructive sleep apnea syndrome (OSAS)...
Adults with ADHD benefit from cognitive-behaviorally oriented group rehabilitation: a study of 29 participantsMaarit Virta
Rinnekoti Research Centre, Finland
J Atten Disord 12:218-26. 2008..In clinical practice, a growing need exists for effective nonpharmacological treatments of adult ADHD. The authors present results from a cognitive-behaviorally oriented psychological group rehabilitation for adult ADHD...
Effects of 6/6 and 4/8 watch systems on sleepiness among bridge officersMikko Härmä
Centre of Expertise on Human Factors at Work, Finnish Institute of Occupational Health, Helsinki, Finland
Chronobiol Int 25:413-23. 2008..The results suggest the 6/6 watch system is related to a higher risk of severe sleepiness during the early morning hours compared to the 4/8 and the other watch systems assessed...
Hypertonic saline injections to enhance the radiofrequency thermal ablation effect in the treatment of base of tongue in obstructive sleep apnoea patients: a pilot studyLeif J J Bäck
Department of Otorhinolaryngology Head and Neck Surgery, Helsinki University Central Hospital, Helsinki, Finland
Acta Otolaryngol 129:302-10. 2009..No significant changes in the measured parameters were encountered, although, several of them showed a clear trend. New treatment modalities are needed to keep multilevel RFA treatment as a minimally invasive procedure...
Heritability of diurnal type: a nationwide study of 8753 adult twin pairsMarkku Koskenvuo
Department of Public Health, University of Helsinki, Helsinki, Finland
J Sleep Res 16:156-62. 2007..7% (95% CI 0-23.7) for additive genetic factors, 38.0% (24.7-51.3) for genetic factors due to dominance. Genetic effects thus account for about one-half of the interindividual variability in diurnal type in adults...
Reported bruxism and restless legs syndrome in media personnel with or without irregular shift workKristiina Ahlberg
Institute of Dentistry, University of Helsinki, Helsinki, Finland
Acta Odontol Scand 63:94-8. 2005..In conclusion, perceived bruxism may be a sign of a stressful situation or dissatisfaction, while RLS as a more stable trait may in itself negatively affect sleep quality and further enhance the problem...
Efficacy of rotigotine for treatment of moderate-to-severe restless legs syndrome: a randomised, double-blind, placebo-controlled trialClaudia Trenkwalder
Paracelsus Elena Hospital, Kassel, Germany
Lancet Neurol 7:595-604. 2008..Continuous administration of a dopamine agonist could be used to treat patients with restless legs syndrome. Our aim was to investigate the efficacy of transdermal rotigotine in the treatment of idiopathic restless legs syndrome...
The impact of somatic health problems on insomnia in middle ageKirsti Martikainen
Community Health Centre of the City of Tampere, Hatanpäänkatu 24, SF 33100 Tampere, Finland
Sleep Med 4:201-6. 2003..The objective of this study is to assess the impact on insomnia symptoms of somatic diseases, psychological factors, living habits and life events during the previous year...
Insomnia and global sleep dissatisfaction in FinlandMaurice M Ohayon
Stanford Sleep Epidemiology Research Center, School of Medicine, Stanford University, Stanford, CA, USA
J Sleep Res 11:339-46. 2002..Compared with other European countries studied with the same methodology (France, the UK, Germany, and Italy), the prevalence of DSM-IV insomnia diagnosis was 1.5 to two times higher in Finland...
Comorbidity in restless legs syndrome among a sample of Swedish adultsJan Ulfberg
Sleep Disorders Center, Avesta Hospital, SE 774 82 Avesta, Sweden
Sleep Med 8:768-72. 2007..However, the comorbidity of this disorder is not well known. This study aimed to document the prevalence of RLS in the general population of Sweden and to identify factors associated with this condition...
Trends in self-reported sleep duration and insomnia-related symptoms in Finland from 1972 to 2005: a comparative review and re-analysis of Finnish population samplesErkki Kronholm
The National Public Health Institute, Turku, Finland
J Sleep Res 17:54-62. 2008..In conclusion, the Finnish data during the past 33 years indicate a general decrease in self-reported sleep duration of about 18 min and an increase of sleep complaints, especially among the employed middle-aged population...
Associations of perceived pain and painless TMD-related symptoms with alexithymia and depressive mood in media personnel with or without irregular shift workJari Ahlberg
Finnish Broadcasting Company, Helsinki, Finland
Acta Odontol Scand 62:119-23. 2004..In the case of perhaps less disabling but common physical symptoms alexithymia as a possible underlying factor may be relevant in the diagnosis and management of such disorders...
Reported bruxism and stress experience in media personnel with or without irregular shift workKristiina Ahlberg
Institute of Dentistry, University of Helsinki, Helsinki, Finland
Acta Odontol Scand 61:315-8. 2003..001). It was concluded that dissatisfaction with one's workshift schedule and not merely irregular shift work may aggravate stress and bruxism...
Content comparison of health-related quality of life instruments for obstructive sleep apneaArmin Stucki
Department of Internal Medicine, University Hospital Bern, Bern, Switzerland
Sleep Med 9:199-206. 2008..The purpose of this study was to compare the content covered by OSA-specific instruments using the ICF...
A cognitive-behavioral weight reduction program in the treatment of obstructive sleep apnea syndrome with or without initial nasal CPAP: a randomized studySoili Kajaste
Haaga Neurological Research Centre, Mäkipellontie 15, 00320 Helsinki, Finland
Sleep Med 5:125-31. 2004....
Perceived orofacial pain and its associations with reported bruxism and insomnia symptoms in media personnel with or without irregular shift workKristiina Ahlberg
Institute of Dentistry, Department of Stomatognathic Physiology and Prosthetic Dentistry, University of Helsinki, Helsinki, Finland
Acta Odontol Scand 63:213-7. 2005..Based on the multivariate analyses, it can be concluded that disrupted sleep and bruxism may be concomitantly involved in the development of orofacial pain...
State of the art in restless legs syndrome therapy: practice recommendations for treating restless legs syndromeWolfgang H Oertel
Department of Neurology, Philipps University, Marburg, Germany
Mov Disord 22:S466-75. 2007..Opioids and anticonvulsants such as gabapentine are second-line options in individual patients. Iron substitution is justified in people with iron deficiency related RLS (ferritin concentration lower than 50 microg/L)...
Effect of controlled-release melatonin on sleep quality, mood, and quality of life in subjects with seasonal or weather-associated changes in mood and behaviourSami Leppämäki
Department of Mental Health and Alcohol Research, National Public Health Institute, Mannerheimintie 166, FIN 00300 Helsinki, Finland
Eur Neuropsychopharmacol 13:137-45. 2003..03) and vitality (P=0.02) in the subjects with s-SAD, but attenuated the improvement of atypical symptoms and physical parameters of quality of life compared to placebo in the subjects with WAS, positive type...
Sleep duration is associated with an increased risk for the prevalence of type 2 diabetes in middle-aged women - The FIN-D2D surveyHenri Tuomilehto
Department of Otorhinolaryngology, Kuopio University Hospital, and University of Kuopio, Finland
Sleep Med 9:221-7. 2008..To examine the association between sleep duration with type 2 diabetes and abnormal glucose tolerance among middle-aged men and women in Finland...
