Markku Partinen

Summary

Affiliation: University of Helsinki
Country: Finland

Publications

  1. ncbi request reprint Narcolepsy as an autoimmune disease: the role of H1N1 infection and vaccination
    Markku Partinen
    Helsinki Sleep Clinic, Vitalmed Research Centre, Helsinki, Finland Department of Clinical Neurosciences, University of Helsinki, Helsinki, Finland Electronic address
    Lancet Neurol 13:600-13. 2014
  2. pmc Effects of exercise and diet interventions on obesity-related sleep disorders in men: study protocol for a randomized controlled trial
    Xiao Tan
    Department of Health Sciences, University of Jyvaskyla, Rautpohjankatu 8, PO Box 35, 40700 Jyväskylä, Finland
    Trials 14:235. 2013
  3. pmc Increased incidence and clinical picture of childhood narcolepsy following the 2009 H1N1 pandemic vaccination campaign in Finland
    Markku Partinen
    Helsinki Sleep Clinic, Vitalmed Research Centre, Helsinki, Finland
    PLoS ONE 7:e33723. 2012
  4. pmc The impacts of nitrous oxide gas on sleep quality during alcohol withdrawal
    Tuuli Lahti
    Department of Mental Health and Substance Abuse Services, National Institute for Health and Welfare, Helsinki, Finland
    BMC Res Notes 4:108. 2011
  5. ncbi request reprint Challenging issues: sleep-wake, augmentation and quality of life
    Markku Partinen
    Skogby Sleep Clinic, Rinnekoti Research Centre, FIN 02980 Espoo Finland
    Sleep Med 8:S19-24. 2007
  6. doi request reprint Cognitive-behaviorally-oriented group rehabilitation of adults with ADHD: results of a 6-month follow-up
    Anita Salakari
    Rinnekoti Research Centre, Finland
    J Atten Disord 13:516-23. 2010
  7. doi request reprint Attenuation of vagal recovery during sleep and reduction of cortisol/melatonin ratio in late afternoon associate with prolonged daytime sleepiness among media workers with irregular shift work
    Harri Lindholm
    Finnish Institute of Occupational Health, Centre of Excellence of Health and Work Ability, Helsinki, Finland
    Am J Ind Med 55:643-9. 2012
  8. doi request reprint Longitudinal study on poor sleep and life dissatisfaction in a nationwide cohort of twins
    Tiina Paunio
    Department of Molecular Medicine, National Public Health Institute, Helsinki, Finland
    Am J Epidemiol 169:206-13. 2009
  9. doi request reprint A dose-ranging study of pramipexole for the symptomatic treatment of restless legs syndrome: polysomnographic evaluation of periodic leg movements and sleep disturbance
    Leni Jama
    Skogby Sleep Clinic, Rinnekoti Research Centre, Kumputie 1, FI 02980 Espoo, Finland
    Sleep Med 10:630-6. 2009
  10. ncbi request reprint Open-label study of the long-term efficacy and safety of pramipexole in patients with Restless Legs Syndrome (extension of the PRELUDE study)
    Markku Partinen
    Skogby Sleep Clinic, Rinnekoti Research Centre, Kumputie 1, FI 02980 Espoo, Finland
    Sleep Med 9:537-41. 2008

Detail Information

Publications42

  1. ncbi request reprint Narcolepsy as an autoimmune disease: the role of H1N1 infection and vaccination
    Markku Partinen
    Helsinki Sleep Clinic, Vitalmed Research Centre, Helsinki, Finland Department of Clinical Neurosciences, University of Helsinki, Helsinki, Finland Electronic address
    Lancet Neurol 13:600-13. 2014
    ..Epidemiological observations from studies in China also suggest a role for H1N1 virus infections as a trigger for narcolepsy. Although the pathological mechanisms are unknown, an H1N1 virus-derived antigen might be the trigger. ..
  2. pmc Effects of exercise and diet interventions on obesity-related sleep disorders in men: study protocol for a randomized controlled trial
    Xiao Tan
    Department of Health Sciences, University of Jyvaskyla, Rautpohjankatu 8, PO Box 35, 40700 Jyväskylä, Finland
    Trials 14:235. 2013
    ....
  3. pmc Increased incidence and clinical picture of childhood narcolepsy following the 2009 H1N1 pandemic vaccination campaign in Finland
    Markku Partinen
    Helsinki Sleep Clinic, Vitalmed Research Centre, Helsinki, Finland
    PLoS ONE 7:e33723. 2012
    ..Therefore, we carried out a systematic analysis of the incidence of narcolepsy in Finland between the years 2002-2010...
  4. pmc The impacts of nitrous oxide gas on sleep quality during alcohol withdrawal
    Tuuli Lahti
    Department of Mental Health and Substance Abuse Services, National Institute for Health and Welfare, Helsinki, Finland
    BMC Res Notes 4:108. 2011
    ..abstract:..
  5. ncbi request reprint Challenging issues: sleep-wake, augmentation and quality of life
    Markku Partinen
    Skogby Sleep Clinic, Rinnekoti Research Centre, FIN 02980 Espoo Finland
    Sleep Med 8:S19-24. 2007
    ..However, augmentation can be controlled by using the lowest possible doses of nonergoline dopamine agonists or by using opioids, gabapentin or anti-epileptics...
  6. doi request reprint Cognitive-behaviorally-oriented group rehabilitation of adults with ADHD: results of a 6-month follow-up
    Anita Salakari
    Rinnekoti Research Centre, Finland
    J Atten Disord 13:516-23. 2010
    ..However, studies about long-term treatment effects are scanty. The authors study effects of cognitive-behaviorally-oriented group rehabilitation during a 6-month follow-up...
  7. doi request reprint Attenuation of vagal recovery during sleep and reduction of cortisol/melatonin ratio in late afternoon associate with prolonged daytime sleepiness among media workers with irregular shift work
    Harri Lindholm
    Finnish Institute of Occupational Health, Centre of Excellence of Health and Work Ability, Helsinki, Finland
    Am J Ind Med 55:643-9. 2012
    ..Media work is characterized by information flow, deadlines, and 24/7 alertness. Good recovery prevents stress-related disorders...
  8. doi request reprint Longitudinal study on poor sleep and life dissatisfaction in a nationwide cohort of twins
    Tiina Paunio
    Department of Molecular Medicine, National Public Health Institute, Helsinki, Finland
    Am J Epidemiol 169:206-13. 2009
    ..21 for men and 0.27 for women in a multivariate genetic model. This finding is consistent with the hypothesis that poor sleep may have direct effects on the brain, emotions, and mood...
  9. doi request reprint A dose-ranging study of pramipexole for the symptomatic treatment of restless legs syndrome: polysomnographic evaluation of periodic leg movements and sleep disturbance
    Leni Jama
    Skogby Sleep Clinic, Rinnekoti Research Centre, Kumputie 1, FI 02980 Espoo, Finland
    Sleep Med 10:630-6. 2009
    ..To evaluate, both polysomnographically and by subjective scales, the efficacy and safety profile of pramipexole for restless legs syndrome (RLS) via a 3-week, double-blind, placebo-controlled, parallel-group, dose-ranging study...
  10. ncbi request reprint Open-label study of the long-term efficacy and safety of pramipexole in patients with Restless Legs Syndrome (extension of the PRELUDE study)
    Markku Partinen
    Skogby Sleep Clinic, Rinnekoti Research Centre, Kumputie 1, FI 02980 Espoo, Finland
    Sleep Med 9:537-41. 2008
    ..To demonstrate the long-term efficacy and safety of pramipexole for Restless Legs Syndrome (RLS) using physician and patient RLS ratings, along with subjective assays of sleep parameters, in a 26-week, open-label trial...
  11. doi request reprint Childhood adversities and quality of sleep in adulthood: A population-based study of 26,000 Finns
    Karoliina Koskenvuo
    Department of Public Health, University of Helsinki, P O Box 41, 00014 Helsinki, Finland
    Sleep Med 11:17-22. 2010
    ..To find out if childhood adversities predict poor sleep quality in working age...
  12. pmc Associations of reported bruxism with insomnia and insufficient sleep symptoms among media personnel with or without irregular shift work
    Kristiina Ahlberg
    Institute of Dentistry, University of Helsinki, Helsinki, Finland
    Head Face Med 4:4. 2008
    ....
  13. pmc AS03 adjuvanted AH1N1 vaccine associated with an abrupt increase in the incidence of childhood narcolepsy in Finland
    Hanna Nohynek
    Department of Vaccines and Immune Protection, National Institute for Health and Welfare, Helsinki, Finland
    PLoS ONE 7:e33536. 2012
    ..A sudden increase in childhood narcolepsy was observed in Finland soon after pandemic influenza epidemic and vaccination with ASO3-adjuvanted Pandemrix. No increase was observed in other age groups...
  14. doi request reprint High job control enhances vagal recovery in media work
    Harri Lindholm
    Centre of Expertise for Health and Work Ability, Finnish Institute of Occupational Health, Helsinki, Finland
    Occup Med (Lond) 59:570-3. 2009
    ..Heart rate variability (HRV) has been widely used to monitor sympathovagal balance. Autonomic imbalance may play an additive role in the development of cardiovascular diseases...
  15. pmc No serological evidence of influenza A H1N1pdm09 virus infection as a contributing factor in childhood narcolepsy after Pandemrix vaccination campaign in Finland
    Krister Melen
    Department of Infectious Disease Surveillance and Control, National Institute for Health and Welfare, Helsinki, Finland
    PLoS ONE 8:e68402. 2013
    ..The analysis was based on the presence or absence of antibody response against non-structural protein 1 (NS1) from H1N1pdm09 virus, which was not a component of Pandemrix vaccine...
  16. doi request reprint Shift-work and cardiovascular disease: a population-based 22-year follow-up study
    Christer Hublin
    Research Center, Finnish Institute of Occupational Health, Helsinki, Finland
    Eur J Epidemiol 25:315-23. 2010
    ..Within twin pairs, no association between shift work and outcome was observed. Our results do not support an association between shift-work and cardiovascular morbidity...
  17. pmc Heritability and mortality risk of insomnia-related symptoms: a genetic epidemiologic study in a population-based twin cohort
    Christer Hublin
    Finnish Institute of Occupational Health, Helsinki, Finland
    Sleep 34:957-64. 2011
    ..Our aim was to estimate heritability in phenotypic insomnia and the association between insomnia and mortality...
  18. pmc Short cognitive behavioral therapy and cognitive training for adults with ADHD - a randomized controlled pilot study
    Maarit Virta
    Rinnekoti Research Centre, Espoo, Finland
    Neuropsychiatr Dis Treat 6:443-53. 2010
    ..These preliminary results warrant further studies with more participants and with more elaborate cognitive testing...
  19. pmc Sleep and mortality: a population-based 22-year follow-up study
    Christer Hublin
    Research Center, Finnish Institute of Occupational Health, Helsinki, Finland
    Sleep 30:1245-53. 2007
    ..Long and short sleep have been associated with increased mortality. We assessed mortality and 3 aspects of sleep behavior in a large cohort with 22-year follow-up...
  20. doi request reprint Genetic factors in evolution of sleep length--a longitudinal twin study in Finnish adults
    Christer Hublin
    Finnish Institute of Occupational Health, Helsinki, Finland Department of Public Health, University of Helsinki, Helsinki, Finland
    J Sleep Res 22:513-8. 2013
    ..In conclusion, genetic factors have a modest but stable effect on the evolution of sleep length over a long time span in adults. Multiple measures are a more robust basis for genetic analyses than a single cross-sectional measure...
  21. ncbi request reprint Efficacy and safety of pramipexole in idiopathic restless legs syndrome: a polysomnographic dose-finding study--the PRELUDE study
    Markku Partinen
    Skogby Sleep Clinic, Rinnekoti Research Centre, Kumputie 3, FI 02980 Espoo, Finland
    Sleep Med 7:407-17. 2006
    ..To evaluate the effects of pramipexole (0.125-0.75 mg/d) on polysomnographic (PSG) measures and patient and clinician ratings of restless legs syndrome (RLS)...
  22. pmc A systematic evaluation of factors associated with nocturia--the population-based FINNO study
    Kari A O Tikkinen
    Clinical Research Institute HUCH Ltd Tutkijatilat H3011, Haartmaninkatu 4, Helsinki, Finland
    Am J Epidemiol 170:361-8. 2009
    ..Although several correlates were identified, none accounted for a substantial proportion of the population burden, highlighting the multifactorial etiology of nocturia...
  23. ncbi request reprint Radiofrequency surgery of the soft palate in the treatment of mild obstructive sleep apnea is not effective as a single-stage procedure: A randomized single-blinded placebo-controlled trial
    Leif J J Bäck
    Department of Otorhinolaryngology, Finland
    Laryngoscope 119:1621-7. 2009
    ..Due to its minimally invasive character, it has received attention in the management of mild obstructive sleep apnea syndrome (OSAS)...
  24. doi request reprint Adults with ADHD benefit from cognitive-behaviorally oriented group rehabilitation: a study of 29 participants
    Maarit Virta
    Rinnekoti Research Centre, Finland
    J Atten Disord 12:218-26. 2008
    ..In clinical practice, a growing need exists for effective nonpharmacological treatments of adult ADHD. The authors present results from a cognitive-behaviorally oriented psychological group rehabilitation for adult ADHD...
  25. doi request reprint Effects of 6/6 and 4/8 watch systems on sleepiness among bridge officers
    Mikko Härmä
    Centre of Expertise on Human Factors at Work, Finnish Institute of Occupational Health, Helsinki, Finland
    Chronobiol Int 25:413-23. 2008
    ..The results suggest the 6/6 watch system is related to a higher risk of severe sleepiness during the early morning hours compared to the 4/8 and the other watch systems assessed...
  26. doi request reprint Unobtrusive online monitoring of sleep at home
    Joonas Paalasmaa
    Department of Computer Science, University of Helsinki, Helsinki, Finland
    Conf Proc IEEE Eng Med Biol Soc 2012:3784-8. 2012
    ..The service has also a medical use, as sleep disorder patients can be measured for long periods before and after interventions...
  27. doi request reprint Hypertonic saline injections to enhance the radiofrequency thermal ablation effect in the treatment of base of tongue in obstructive sleep apnoea patients: a pilot study
    Leif J J Bäck
    Department of Otorhinolaryngology Head and Neck Surgery, Helsinki University Central Hospital, Helsinki, Finland
    Acta Otolaryngol 129:302-10. 2009
    ..No significant changes in the measured parameters were encountered, although, several of them showed a clear trend. New treatment modalities are needed to keep multilevel RFA treatment as a minimally invasive procedure...
  28. ncbi request reprint Reported bruxism and restless legs syndrome in media personnel with or without irregular shift work
    Kristiina Ahlberg
    Institute of Dentistry, University of Helsinki, Helsinki, Finland
    Acta Odontol Scand 63:94-8. 2005
    ..In conclusion, perceived bruxism may be a sign of a stressful situation or dissatisfaction, while RLS as a more stable trait may in itself negatively affect sleep quality and further enhance the problem...
  29. ncbi request reprint Heritability of diurnal type: a nationwide study of 8753 adult twin pairs
    Markku Koskenvuo
    Department of Public Health, University of Helsinki, Helsinki, Finland
    J Sleep Res 16:156-62. 2007
    ..7% (95% CI 0-23.7) for additive genetic factors, 38.0% (24.7-51.3) for genetic factors due to dominance. Genetic effects thus account for about one-half of the interindividual variability in diurnal type in adults...
  30. ncbi request reprint Insomnia and global sleep dissatisfaction in Finland
    Maurice M Ohayon
    Stanford Sleep Epidemiology Research Center, School of Medicine, Stanford University, Stanford, CA, USA
    J Sleep Res 11:339-46. 2002
    ..Compared with other European countries studied with the same methodology (France, the UK, Germany, and Italy), the prevalence of DSM-IV insomnia diagnosis was 1.5 to two times higher in Finland...
  31. ncbi request reprint Comorbidity in restless legs syndrome among a sample of Swedish adults
    Jan Ulfberg
    Sleep Disorders Center, Avesta Hospital, SE 774 82 Avesta, Sweden
    Sleep Med 8:768-72. 2007
    ..However, the comorbidity of this disorder is not well known. This study aimed to document the prevalence of RLS in the general population of Sweden and to identify factors associated with this condition...
  32. doi request reprint Trends in self-reported sleep duration and insomnia-related symptoms in Finland from 1972 to 2005: a comparative review and re-analysis of Finnish population samples
    Erkki Kronholm
    The National Public Health Institute, Turku, Finland
    J Sleep Res 17:54-62. 2008
    ..In conclusion, the Finnish data during the past 33 years indicate a general decrease in self-reported sleep duration of about 18 min and an increase of sleep complaints, especially among the employed middle-aged population...
  33. ncbi request reprint The impact of somatic health problems on insomnia in middle age
    Kirsti Martikainen
    Community Health Centre of the City of Tampere, Hatanpäänkatu 24, SF 33100 Tampere, Finland
    Sleep Med 4:201-6. 2003
    ..The objective of this study is to assess the impact on insomnia symptoms of somatic diseases, psychological factors, living habits and life events during the previous year...
  34. ncbi request reprint Associations of perceived pain and painless TMD-related symptoms with alexithymia and depressive mood in media personnel with or without irregular shift work
    Jari Ahlberg
    Finnish Broadcasting Company, Helsinki, Finland
    Acta Odontol Scand 62:119-23. 2004
    ..In the case of perhaps less disabling but common physical symptoms alexithymia as a possible underlying factor may be relevant in the diagnosis and management of such disorders...
  35. ncbi request reprint Efficacy of rotigotine for treatment of moderate-to-severe restless legs syndrome: a randomised, double-blind, placebo-controlled trial
    Claudia Trenkwalder
    Paracelsus Elena Hospital, Kassel, Germany
    Lancet Neurol 7:595-604. 2008
    ..Continuous administration of a dopamine agonist could be used to treat patients with restless legs syndrome. Our aim was to investigate the efficacy of transdermal rotigotine in the treatment of idiopathic restless legs syndrome...
  36. ncbi request reprint Sleep duration is associated with an increased risk for the prevalence of type 2 diabetes in middle-aged women - The FIN-D2D survey
    Henri Tuomilehto
    Department of Otorhinolaryngology, Kuopio University Hospital, and University of Kuopio, Finland
    Sleep Med 9:221-7. 2008
    ..To examine the association between sleep duration with type 2 diabetes and abnormal glucose tolerance among middle-aged men and women in Finland...
  37. ncbi request reprint Effect of controlled-release melatonin on sleep quality, mood, and quality of life in subjects with seasonal or weather-associated changes in mood and behaviour
    Sami Leppämäki
    Department of Mental Health and Alcohol Research, National Public Health Institute, Mannerheimintie 166, FIN 00300 Helsinki, Finland
    Eur Neuropsychopharmacol 13:137-45. 2003
    ..03) and vitality (P=0.02) in the subjects with s-SAD, but attenuated the improvement of atypical symptoms and physical parameters of quality of life compared to placebo in the subjects with WAS, positive type...
  38. ncbi request reprint Reported bruxism and stress experience in media personnel with or without irregular shift work
    Kristiina Ahlberg
    Institute of Dentistry, University of Helsinki, Helsinki, Finland
    Acta Odontol Scand 61:315-8. 2003
    ..001). It was concluded that dissatisfaction with one's workshift schedule and not merely irregular shift work may aggravate stress and bruxism...
  39. ncbi request reprint A cognitive-behavioral weight reduction program in the treatment of obstructive sleep apnea syndrome with or without initial nasal CPAP: a randomized study
    Soili Kajaste
    Haaga Neurological Research Centre, Mäkipellontie 15, 00320 Helsinki, Finland
    Sleep Med 5:125-31. 2004
    ....
  40. ncbi request reprint Perceived orofacial pain and its associations with reported bruxism and insomnia symptoms in media personnel with or without irregular shift work
    Kristiina Ahlberg
    Institute of Dentistry, Department of Stomatognathic Physiology and Prosthetic Dentistry, University of Helsinki, Helsinki, Finland
    Acta Odontol Scand 63:213-7. 2005
    ..Based on the multivariate analyses, it can be concluded that disrupted sleep and bruxism may be concomitantly involved in the development of orofacial pain...
  41. ncbi request reprint Content comparison of health-related quality of life instruments for obstructive sleep apnea
    Armin Stucki
    Department of Internal Medicine, University Hospital Bern, Bern, Switzerland
    Sleep Med 9:199-206. 2008
    ..The purpose of this study was to compare the content covered by OSA-specific instruments using the ICF...
  42. ncbi request reprint State of the art in restless legs syndrome therapy: practice recommendations for treating restless legs syndrome
    Wolfgang H Oertel
    Department of Neurology, Philipps University, Marburg, Germany
    Mov Disord 22:S466-75. 2007
    ..Opioids and anticonvulsants such as gabapentine are second-line options in individual patients. Iron substitution is justified in people with iron deficiency related RLS (ferritin concentration lower than 50 microg/L)...