S Paju

Summary

Affiliation: University of Helsinki
Country: Finland

Publications

  1. pmc Oral biofilms, periodontitis, and pulmonary infections
    S Paju
    Institute of Dentistry, University of Helsinki, Helsinki, Finland
    Oral Dis 13:508-12. 2007
  2. pmc Heterogeneity of Actinobacillus actinomycetemcomitans strains in various human infections and relationships between serotype, genotype, and antimicrobial susceptibility
    S Paju
    Institute of Dentistry, University of Helsinki, Helsinki, Finland
    J Clin Microbiol 38:79-84. 2000
  3. pmc Detection of multiple pathogenic species in saliva is associated with periodontal infection in adults
    Susanna Paju
    Institute of Dentistry, PL 41, FI 00014 University of Helsinki, Helsinki, Finland
    J Clin Microbiol 47:235-8. 2009
  4. ncbi request reprint Is periodontal infection behind the failure of antibiotics to prevent coronary events?
    Susanna Paju
    Institute of Dentistry, University of Helsinki and Department of Oral and Maxillofacial Diseases, Helsinki University Central Hospital, PO Box 63, 00014 Helsinki, Finland
    Atherosclerosis 193:193-5. 2007
  5. ncbi request reprint Localization of heat shock proteins in clinical Actinobacillus actinomycetemcomitans strains and their effects on epithelial cell proliferation
    S Paju
    Institute of Dentistry, University of Helsinki, P O Box 41, FIN 00014, Helsinki, Finland
    FEMS Microbiol Lett 182:231-5. 2000
  6. ncbi request reprint Altered antigenicity is seen in the lipopolysaccharide profile of non-serotypeable Actinobacillus actinomycetemcomitans strains
    S Paju
    Institute of Dentistry, P O Box 41, University of Helsinki, FIN 00014, Helsinki, Finland
    FEMS Immunol Med Microbiol 27:171-7. 2000
  7. doi request reprint Periodontopathogen- and host-derived immune response in acute coronary syndrome
    H Alfakry
    Institute of Dentistry, University of Helsinki, Helsinki, Finland
    Scand J Immunol 74:383-9. 2011
  8. doi request reprint Lymphotoxin alpha LTA+496C allele is a risk factor for periodontitis in patients with coronary artery disease
    A Palikhe
    Department of Medicine, Helsinki University Central Hospital, Helsinki, Finland
    Tissue Antigens 71:530-7. 2008
  9. doi request reprint Bruxism and sleep efficiency measured at home with wireless devices
    K Ahlberg
    Department of Stomatognathic Physiology and Prosthetic Dentistry, Institute of Dentistry, University of Helsinki, Helsinki, Finland
    J Oral Rehabil 35:567-71. 2008
  10. ncbi request reprint Serum microbial- and host-derived markers of periodontal diseases: a review
    Pirkko J Pussinen
    Institute of Dentistry, University of Helsinki, Finland
    Curr Med Chem 14:2402-12. 2007

Detail Information

Publications20

  1. pmc Oral biofilms, periodontitis, and pulmonary infections
    S Paju
    Institute of Dentistry, University of Helsinki, Helsinki, Finland
    Oral Dis 13:508-12. 2007
    ..The present paper critically reviews the recent literature on the effect of oral biofilms and periodontitis on pneumonia...
  2. pmc Heterogeneity of Actinobacillus actinomycetemcomitans strains in various human infections and relationships between serotype, genotype, and antimicrobial susceptibility
    S Paju
    Institute of Dentistry, University of Helsinki, Helsinki, Finland
    J Clin Microbiol 38:79-84. 2000
    ..The mechanisms behind the exceptionally high rate of occurrence of benzylpenicillin resistance among A. actinomycetemcomitans serotype b strains are to be elucidated in further studies...
  3. pmc Detection of multiple pathogenic species in saliva is associated with periodontal infection in adults
    Susanna Paju
    Institute of Dentistry, PL 41, FI 00014 University of Helsinki, Helsinki, Finland
    J Clin Microbiol 47:235-8. 2009
    ..In 1,198 subjects, the detection of multiple species, rather than the presence of a certain pathogen, in saliva was associated with periodontitis as determined by the number of teeth with deepened periodontal pockets...
  4. ncbi request reprint Is periodontal infection behind the failure of antibiotics to prevent coronary events?
    Susanna Paju
    Institute of Dentistry, University of Helsinki and Department of Oral and Maxillofacial Diseases, Helsinki University Central Hospital, PO Box 63, 00014 Helsinki, Finland
    Atherosclerosis 193:193-5. 2007
    ..We discuss the systemic effects of periodontal infection and consider studies to test our hypothesis, which offers a novel viewpoint for discussion of antibiotics in coronary-disease prevention...
  5. ncbi request reprint Localization of heat shock proteins in clinical Actinobacillus actinomycetemcomitans strains and their effects on epithelial cell proliferation
    S Paju
    Institute of Dentistry, University of Helsinki, P O Box 41, FIN 00014, Helsinki, Finland
    FEMS Microbiol Lett 182:231-5. 2000
    ..The results suggest that GroEL-like Hsp may play a role in the virulence of A. actinomycetemcomitans by increasing epithelial proliferation...
  6. ncbi request reprint Altered antigenicity is seen in the lipopolysaccharide profile of non-serotypeable Actinobacillus actinomycetemcomitans strains
    S Paju
    Institute of Dentistry, P O Box 41, University of Helsinki, FIN 00014, Helsinki, Finland
    FEMS Immunol Med Microbiol 27:171-7. 2000
    ..The results suggest that changes in LPS lead to the altered antigenicity of non-serotypeable A. actinomycetemcomitans strains...
  7. doi request reprint Periodontopathogen- and host-derived immune response in acute coronary syndrome
    H Alfakry
    Institute of Dentistry, University of Helsinki, Helsinki, Finland
    Scand J Immunol 74:383-9. 2011
    ..Despite the observed cross-reactivity in the systemic IgG-class antibody response to HSP60 and A. actinomycetemcomitans, the pathogen carriage in saliva or the periodontal status did not affect the HSP60 antibody levels in ACS patients...
  8. doi request reprint Lymphotoxin alpha LTA+496C allele is a risk factor for periodontitis in patients with coronary artery disease
    A Palikhe
    Department of Medicine, Helsinki University Central Hospital, Helsinki, Finland
    Tissue Antigens 71:530-7. 2008
    ..56; 95% CI = 1.05-2.30; P = 0.026) remained as significant risk factors for periodontitis. In conclusion, the major finding of this study is that the LTA+496C allele is associated with periodontitis in patients with CAD...
  9. doi request reprint Bruxism and sleep efficiency measured at home with wireless devices
    K Ahlberg
    Department of Stomatognathic Physiology and Prosthetic Dentistry, Institute of Dentistry, University of Helsinki, Helsinki, Finland
    J Oral Rehabil 35:567-71. 2008
    ..013). It was concluded that bruxism has a coherent relationship with sleep efficiency and it can be detected at home with a low cost device...
  10. ncbi request reprint Serum microbial- and host-derived markers of periodontal diseases: a review
    Pirkko J Pussinen
    Institute of Dentistry, University of Helsinki, Finland
    Curr Med Chem 14:2402-12. 2007
    ..Based on literature review, we encourage research and development of serum screening methods for periodontitis that could be used by general physicians...
  11. ncbi request reprint Aggregatibacter actinomycetemcomitans induces MMP-9 expression and proatherogenic lipoprotein profile in apoE-deficient mice
    Anita M Tuomainen
    Institute of Dentistry, University of Helsinki, Helsinki, Finland
    Microb Pathog 44:111-7. 2008
    ..The results indicate that A. actinomycetemcomitans contributes to disturbed lipoprotein profiles, inflammatory reaction, and matrix remodelling which are known to promote the development of atherosclerosis...
  12. pmc Population-based study of salivary carriage of periodontal pathogens in adults
    Eija Kononen
    Anaerobe Reference Laboratory, Department of Bacterial and Inflammatory Diseases, National Public Health Institute KTL, Mannerheimintie 166, FI 00300 Helsinki, Finland
    J Clin Microbiol 45:2446-51. 2007
    ..000), T. denticola (P = 0.000), and A. actinomycetemcomitans (P = 0.004). The data suggest that distinct species have a different carriage profile, depending on variables such as age, educational level, and periodontal status...
  13. pmc Actinobacillus actinomycetemcomitans serotype d-specific antigen contains the O antigen of lipopolysaccharide
    Laura Lakio
    Institute of Dentistry, University of Helsinki, and Department of Oral and Maxillofacial Diseases, Helsinki University Central Hospital, Finland
    Infect Immun 71:5005-11. 2003
    ..actinomycetemcomitans serotype d. In conclusion, our results show that the A. actinomycetemcomitans serotype d-specific antigen contains the O-antigenic structure of LPS...
  14. ncbi request reprint Systemic exposure to Porphyromonas gingivalis predicts incident stroke
    Pirkko J Pussinen
    Institute of Dentistry, University of Helsinki, PO Box 63, FI 00014 Helsinki, Finland
    Atherosclerosis 193:222-8. 2007
    ..31 (1.31-8.40, p=0.012) for stroke. No association between antibody levels to Actinobacillus actinomycetemcomitans and stroke was found. The results suggest that the systemic exposure to P. gingivalis may predispose to incident stroke...
  15. ncbi request reprint Clarithromycin reduces recurrent cardiovascular events in subjects without periodontitis
    Susanna Paju
    Institute of Dentistry, University of Helsinki, and Department of Oral and Maxillofacial Diseases, Helsinki University Central Hospital, Helsinki, Finland
    Atherosclerosis 188:412-9. 2006
    ..Long-term clarithromycin therapy seems to be beneficial in prevention of recurrent cardiovascular events in non-periodontitis but not in periodontitis patients...
  16. ncbi request reprint Dental infections and cardiovascular diseases: a review
    Kimmo J Mattila
    Helsinki University Central Hospital, Division of Infectious Diseases, Helsinki, Finland
    J Periodontol 76:2085-8. 2005
    ..This may be due to genetic reasons and may also apply to other chronic low-grade infections...
  17. ncbi request reprint Actinobacillus actinomycetemcomitans and Haemophilus aphrophilus in systemic and nonoral infections in Finland
    Susanna Paju
    Institute of Dentistry, University of Helsinki, Finland
    APMIS 111:653-7. 2003
    ....
  18. ncbi request reprint Associations between periodontal disease and risk for nosocomial bacterial pneumonia and chronic obstructive pulmonary disease. A systematic review
    Frank A Scannapieco
    Department of Oral Biology, School of Dental Medicine, University at Buffalo, State University of New York, Buffalo, New York, USA
    Ann Periodontol 8:54-69. 2003
    ..Several recent studies provide evidence that the oral cavity may influence the initiation and/or the progression of lung diseases such as pneumonia and chronic obstructive pulmonary disease (COPD)...
  19. pmc Amylase-binding protein B of Streptococcus gordonii is an extracellular dipeptidyl-peptidase
    Biswendu Chaudhuri
    Department of Oral Biology, School of Dental Medicine, State University of New York at Buffalo, Buffalo, New York 14214, USA
    Infect Immun 76:4530-7. 2008
    ..In summary, AbpB demonstrates proteolytic activity and interacts with and modulates Gtf activity. These activities may help explain the crucial role AbpB appears to play in S. gordonii oral colonization...
  20. ncbi request reprint Associations between periodontal disease and risk for atherosclerosis, cardiovascular disease, and stroke. A systematic review
    Frank A Scannapieco
    Department of Oral Biology, School of Dental Medicine, University at Buffalo, State University of New York, Buffalo, New York, USA
    Ann Periodontol 8:38-53. 2003
    ..Recent studies implicate exposure to systemic conditions involving chronic inflammation, including chronic periodontitis, in the etiology of atherosclerosis...