Research Topics
| Steffen OhlmeierSummaryAffiliation: University of Oulu Country: Finland Publications
| Collaborators
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Detail Information
Publications
Hemoglobin α and β are ubiquitous in the human lung, decline in idiopathic pulmonary fibrosis but not in COPDNobuhisa Ishikawa
Department of Medicine, Pulmonary Division, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland
Respir Res 11:123. 2010..They share the common denominators of a progressive nature and poor prognosis. The goal was to use non-biased proteomics to discover new markers for these diseases...
The yeast mitochondrial proteome, a study of fermentative and respiratory growthSteffen Ohlmeier
Biocenter Oulu and Department of Biochemistry, P O Box 3000, University of Oulu, Oulu FIN 90014, Finland
J Biol Chem 279:3956-79. 2004..We propose that the discrepancy between proteome and transcriptional regulation, apart from different translation efficiency, indicates a changed turnover rate of proteins in different physiological conditions...
Protein phosphorylation in mitochondria --a study on fermentative and respiratory growth of Saccharomyces cerevisiaeSteffen Ohlmeier
Proteomics Core Facility, Biocenter Oulu, and Department of Biochemistry, University of Oulu, Oulu, Finland
Electrophoresis 31:2869-81. 2010..g. glucose fermentation, tricarboxylic acid cycle, pyruvate dehydrogenase and its bypass) and respiratory chain...
Sputum proteomics identifies elevated PIGR levels in smokers and mild-to-moderate COPDSteffen Ohlmeier
Proteomics Core Facility, Biocenter Oulu, Department of Biochemistry, University of Oulu, Oulu, Finland
J Proteome Res 11:599-608. 2012..In conclusion, new proteins in smoking-related chronic inflammation and COPD could be identified, with SC/PIGR being one of the most prominent not only in the lung but also in circulating blood...
Proteomic studies on receptor for advanced glycation end product variants in idiopathic pulmonary fibrosis and chronic obstructive pulmonary diseaseSteffen Ohlmeier
Biocenter Oulu, Department of Biochemistry, University of Oulu, Finland
Proteomics Clin Appl 4:97-105. 2010..This study was undertaken to investigate the different RAGE isoforms in two lung diseases with destruction of the lung parenchyma, i.e. IPF and chronic obstructive pulmonary disease (COPD)...
UK114, a YjgF/Yer057p/UK114 family protein highly conserved from bacteria to mammals, is localized in rat liver peroxisomesVasily D Antonenkov
Department of Biochemistry, Biocenter Oulu, University of Oulu, Linnanmaa, P O Box 3000, FIN 90014 Oulu, Finland
Biochem Biophys Res Commun 357:252-7. 2007..The peroxisomal UK114 is a soluble matrix protein and it is not inducible by the peroxisomal proliferator clofibrate. The data predict involvement of UK114 in peroxisomal metabolism...
Localization of a portion of the liver isoform of fatty-acid-binding protein (L-FABP) to peroxisomesVasily D Antonenkov
Department of Biochemistry, Biocenter Oulu, University of Oulu, Linnanmaa, P O Box 3000, FIN 90014 Oulu, Finland
Biochem J 394:475-84. 2006..The possible role of intraperoxisomal L-FABP in lipid metabolism is discussed...
Tumor necrosis factor alpha promotes the expression of immunosuppressive proteins and enhances the cell growth in a human bone marrow-derived stem cell cultureJohanna A Miettinen
Institute of Clinical Medicine, Department of Internal Medicine, University of Oulu, P O Box 5000, FIN 90014 Oulu, Finland
Exp Cell Res 317:791-801. 2011..These results strongly support reactive and immunosuppressive activation of MSCs during TNF-α exposure, which might influence MSC differentiation stage and capacity...
Peroxisomes are oxidative organellesVasily D Antonenkov
Department of Biochemistry, University of Oulu, Oulu, Finland
Antioxid Redox Signal 13:525-37. 2010..Antioxid...
Proteomics of human lung tissue identifies surfactant protein A as a marker of chronic obstructive pulmonary diseaseSteffen Ohlmeier
Department of Biochemistry, Proteomics Core Facility, Biocenter Oulu, University of Oulu, Oulu, Finland
J Proteome Res 7:5125-32. 2008..The levels of other surfactant proteins (SP-B, SP-C, SP-D) were not altered. Our results suggest that SP-A is linked to the pathogenesis of COPD and could be considered as a potential COPD biomarker...
Proteome and cytoskeleton responses in osteosarcoma cells with reduced OXPHOS activityJohanna Annunen Rasila
Department of Neurology, University of Oulu, Oulu, Finland
Proteomics 7:2189-200. 2007..Our findings suggest that a deficiency in the energy converting system and oxidative stress can lead to cytoskeletal changes...
Does the oxidative stress in chronic obstructive pulmonary disease cause thioredoxin/peroxiredoxin oxidation?Siri T Lehtonen
Department of Internal Medicine, University of Oulu and Oulu University Hospital, Oulu, Finland
Antioxid Redox Signal 10:813-9. 2008..Our study shows that the thiol status of the Trx/Prx-system can be modulated in vitro, but it appears to have high resistance against the oxidative stress in COPD...
NO-mediated apoptosis in yeastBruno Almeida
Life and Health Sciences Research Institute ICVS, School of Health Sciences, University of Minho, Campus de Gualtar, 4710 057 Braga, Portugal
J Cell Sci 120:3279-88. 2007..Evidence is presented showing that NO and GAPDH S-nitrosation also mediate cell death during chronological life span pointing to a physiological role of NO in yeast apoptosis...
