Steffen Ohlmeier

Summary

Affiliation: University of Oulu
Country: Finland

Publications

  1. pmc Hemoglobin α and β are ubiquitous in the human lung, decline in idiopathic pulmonary fibrosis but not in COPD
    Nobuhisa Ishikawa
    Department of Medicine, Pulmonary Division, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland
    Respir Res 11:123. 2010
  2. ncbi request reprint The yeast mitochondrial proteome, a study of fermentative and respiratory growth
    Steffen Ohlmeier
    Biocenter Oulu and Department of Biochemistry, P O Box 3000, University of Oulu, Oulu FIN 90014, Finland
    J Biol Chem 279:3956-79. 2004
  3. doi request reprint Protein phosphorylation in mitochondria --a study on fermentative and respiratory growth of Saccharomyces cerevisiae
    Steffen Ohlmeier
    Proteomics Core Facility, Biocenter Oulu, and Department of Biochemistry, University of Oulu, Oulu, Finland
    Electrophoresis 31:2869-81. 2010
  4. doi request reprint Sputum proteomics identifies elevated PIGR levels in smokers and mild-to-moderate COPD
    Steffen Ohlmeier
    Proteomics Core Facility, Biocenter Oulu, Department of Biochemistry, University of Oulu, Oulu, Finland
    J Proteome Res 11:599-608. 2012
  5. doi request reprint Proteomic studies on receptor for advanced glycation end product variants in idiopathic pulmonary fibrosis and chronic obstructive pulmonary disease
    Steffen Ohlmeier
    Biocenter Oulu, Department of Biochemistry, University of Oulu, Finland
    Proteomics Clin Appl 4:97-105. 2010
  6. pmc Localization of a portion of the liver isoform of fatty-acid-binding protein (L-FABP) to peroxisomes
    Vasily D Antonenkov
    Department of Biochemistry, Biocenter Oulu, University of Oulu, Linnanmaa, P O Box 3000, FIN 90014 Oulu, Finland
    Biochem J 394:475-84. 2006
  7. ncbi request reprint UK114, a YjgF/Yer057p/UK114 family protein highly conserved from bacteria to mammals, is localized in rat liver peroxisomes
    Vasily D Antonenkov
    Department of Biochemistry, Biocenter Oulu, University of Oulu, Linnanmaa, P O Box 3000, FIN 90014 Oulu, Finland
    Biochem Biophys Res Commun 357:252-7. 2007
  8. doi request reprint Tumor necrosis factor alpha promotes the expression of immunosuppressive proteins and enhances the cell growth in a human bone marrow-derived stem cell culture
    Johanna A Miettinen
    Institute of Clinical Medicine, Department of Internal Medicine, University of Oulu, P O Box 5000, FIN 90014 Oulu, Finland
    Exp Cell Res 317:791-801. 2011
  9. doi request reprint Peroxisomes are oxidative organelles
    Vasily D Antonenkov
    Department of Biochemistry, University of Oulu, Oulu, Finland
    Antioxid Redox Signal 13:525-37. 2010
  10. doi request reprint Proteomics of human lung tissue identifies surfactant protein A as a marker of chronic obstructive pulmonary disease
    Steffen Ohlmeier
    Department of Biochemistry, Proteomics Core Facility, Biocenter Oulu, University of Oulu, Oulu, Finland
    J Proteome Res 7:5125-32. 2008

Collaborators

Detail Information

Publications15

  1. pmc Hemoglobin α and β are ubiquitous in the human lung, decline in idiopathic pulmonary fibrosis but not in COPD
    Nobuhisa Ishikawa
    Department of Medicine, Pulmonary Division, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland
    Respir Res 11:123. 2010
    ..They share the common denominators of a progressive nature and poor prognosis. The goal was to use non-biased proteomics to discover new markers for these diseases...
  2. ncbi request reprint The yeast mitochondrial proteome, a study of fermentative and respiratory growth
    Steffen Ohlmeier
    Biocenter Oulu and Department of Biochemistry, P O Box 3000, University of Oulu, Oulu FIN 90014, Finland
    J Biol Chem 279:3956-79. 2004
    ..We propose that the discrepancy between proteome and transcriptional regulation, apart from different translation efficiency, indicates a changed turnover rate of proteins in different physiological conditions...
  3. doi request reprint Protein phosphorylation in mitochondria --a study on fermentative and respiratory growth of Saccharomyces cerevisiae
    Steffen Ohlmeier
    Proteomics Core Facility, Biocenter Oulu, and Department of Biochemistry, University of Oulu, Oulu, Finland
    Electrophoresis 31:2869-81. 2010
    ..g. glucose fermentation, tricarboxylic acid cycle, pyruvate dehydrogenase and its bypass) and respiratory chain...
  4. doi request reprint Sputum proteomics identifies elevated PIGR levels in smokers and mild-to-moderate COPD
    Steffen Ohlmeier
    Proteomics Core Facility, Biocenter Oulu, Department of Biochemistry, University of Oulu, Oulu, Finland
    J Proteome Res 11:599-608. 2012
    ..In conclusion, new proteins in smoking-related chronic inflammation and COPD could be identified, with SC/PIGR being one of the most prominent not only in the lung but also in circulating blood...
  5. doi request reprint Proteomic studies on receptor for advanced glycation end product variants in idiopathic pulmonary fibrosis and chronic obstructive pulmonary disease
    Steffen Ohlmeier
    Biocenter Oulu, Department of Biochemistry, University of Oulu, Finland
    Proteomics Clin Appl 4:97-105. 2010
    ..This study was undertaken to investigate the different RAGE isoforms in two lung diseases with destruction of the lung parenchyma, i.e. IPF and chronic obstructive pulmonary disease (COPD)...
  6. pmc Localization of a portion of the liver isoform of fatty-acid-binding protein (L-FABP) to peroxisomes
    Vasily D Antonenkov
    Department of Biochemistry, Biocenter Oulu, University of Oulu, Linnanmaa, P O Box 3000, FIN 90014 Oulu, Finland
    Biochem J 394:475-84. 2006
    ..The possible role of intraperoxisomal L-FABP in lipid metabolism is discussed...
  7. ncbi request reprint UK114, a YjgF/Yer057p/UK114 family protein highly conserved from bacteria to mammals, is localized in rat liver peroxisomes
    Vasily D Antonenkov
    Department of Biochemistry, Biocenter Oulu, University of Oulu, Linnanmaa, P O Box 3000, FIN 90014 Oulu, Finland
    Biochem Biophys Res Commun 357:252-7. 2007
    ..The peroxisomal UK114 is a soluble matrix protein and it is not inducible by the peroxisomal proliferator clofibrate. The data predict involvement of UK114 in peroxisomal metabolism...
  8. doi request reprint Tumor necrosis factor alpha promotes the expression of immunosuppressive proteins and enhances the cell growth in a human bone marrow-derived stem cell culture
    Johanna A Miettinen
    Institute of Clinical Medicine, Department of Internal Medicine, University of Oulu, P O Box 5000, FIN 90014 Oulu, Finland
    Exp Cell Res 317:791-801. 2011
    ..These results strongly support reactive and immunosuppressive activation of MSCs during TNF-α exposure, which might influence MSC differentiation stage and capacity...
  9. doi request reprint Peroxisomes are oxidative organelles
    Vasily D Antonenkov
    Department of Biochemistry, University of Oulu, Oulu, Finland
    Antioxid Redox Signal 13:525-37. 2010
    ..Antioxid...
  10. doi request reprint Proteomics of human lung tissue identifies surfactant protein A as a marker of chronic obstructive pulmonary disease
    Steffen Ohlmeier
    Department of Biochemistry, Proteomics Core Facility, Biocenter Oulu, University of Oulu, Oulu, Finland
    J Proteome Res 7:5125-32. 2008
    ..The levels of other surfactant proteins (SP-B, SP-C, SP-D) were not altered. Our results suggest that SP-A is linked to the pathogenesis of COPD and could be considered as a potential COPD biomarker...
  11. doi request reprint Characterization of chronic subdural hematoma fluid proteome
    Anna Leena Heula
    Department of Clinical Medicine, Neurosurgery, University of Oulu, Oulu, Finland Department of Neurosurgery, Oulu University Hospital, Oulu, Finland Department of Clinical Medicine, Neurology, University of Oulu, Oulu, Finland Department of Neurology, Oulu University Hospital, Oulu, Finland Clinical Research Center, Oulu University Hospital, Oulu, Finland Proteomics Core Facility, Biocenter Oulu, Department of Biochemistry, University of Oulu, Oulu, Finland Department of Surgery and Department of Neurology, Seinajoki Central Hospital, Seinajoki, Finland
    Neurosurgery 73:317-31. 2013
    ..The protein composition of the CSDH fluid has not been fully elucidated, nor has the contribution of its components to the enlargement of the hematoma cavity and to its chronic manifestation...
  12. ncbi request reprint Proteome and cytoskeleton responses in osteosarcoma cells with reduced OXPHOS activity
    Johanna Annunen-Rasila
    Department of Neurology, University of Oulu, Oulu, Finland
    Proteomics 7:2189-200. 2007
    ..Our findings suggest that a deficiency in the energy converting system and oxidative stress can lead to cytoskeletal changes...
  13. ncbi request reprint Analysis of molecular changes after autologous cell therapy in swine myocardial infarction tissue can reveal novel targets for future therapy
    Siri T Lehtonen
    Institute of Clinical Medicine, Department of Surgery and Clinical Research Center, Oulu University Hospital and University of Oulu, Finland Institute of Biomedicine, Department of Anatomy and Cell Biology, University of Oulu, Finland
    J Tissue Eng Regen Med 8:97-105. 2014
    ..This study reveals that cell therapy with BMMCs after myocardial infarction causes restoration of several altered protein levels after 3 weeks and identifies potential marker proteins involved in the pathology of infarction...
  14. doi request reprint Does the oxidative stress in chronic obstructive pulmonary disease cause thioredoxin/peroxiredoxin oxidation?
    Siri T Lehtonen
    Department of Internal Medicine, University of Oulu and Oulu University Hospital, Oulu, Finland
    Antioxid Redox Signal 10:813-9. 2008
    ..Our study shows that the thiol status of the Trx/Prx-system can be modulated in vitro, but it appears to have high resistance against the oxidative stress in COPD...
  15. ncbi request reprint NO-mediated apoptosis in yeast
    Bruno Almeida
    Life and Health Sciences Research Institute ICVS, School of Health Sciences, University of Minho, Campus de Gualtar, 4710 057 Braga, Portugal
    J Cell Sci 120:3279-88. 2007
    ..Evidence is presented showing that NO and GAPDH S-nitrosation also mediate cell death during chronological life span pointing to a physiological role of NO in yeast apoptosis...