Research Topics
Genomes and GenesSpecies | Harri NiinikoskiSummaryAffiliation: University of Turku Country: Finland Publications
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Detail Information
Publications
Alexander disease as a cause of nocturnal vomiting in a 7-year-old girlHarri Niinikoski
Department of Paediatrics, University of Turku, Kiinamyllynkatu 4 8, Turku, 20900, Finland
Pediatr Radiol 39:872-5. 2009..Alexander disease should be considered in young patients with atypical anorexia nervosa-type symptoms...
Growth hormone therapy is safe and effective in patients with lysinuric protein intoleranceHarri Niinikoski
Department of Pediatrics, University of Turku, Kiinamyllynkatu 4 8, Turku, Finland
JIMD Rep 1:43-7. 2011..7-1.8 SDS. There were no episodes of hyperammonemias. Conclusions: Our data support safety and growth-promoting potential of long-term GH therapy in patients with LPI...
Is carbohydrate intake in the first years of life related to future risk of NCDs?H Niinikoski
Turku University Hospital, Department of Pediatrics, Kiinamyllynkatu 4 8, 20520 Turku, Finland
Nutr Metab Cardiovasc Dis 22:770-4. 2012..Clinical Trial Registration Information: NCT00223600...
Blood pressure is lower in children and adolescents with a low-saturated-fat diet since infancy: the special turku coronary risk factor intervention projectHarri Niinikoski
Department of Pediatrics, Turku University Hospital, Turku, Finland
Hypertension 53:918-24. 2009..The importance of childhood lifestyle counseling and primary prevention of hypertension should be emphasized, especially in those children with a family history of hypertension or atherosclerotic vascular disease...
Impact of repeated dietary counseling between infancy and 14 years of age on dietary intakes and serum lipids and lipoproteins: the STRIP studyHarri Niinikoski
Department of Pediatrics, University of Turku, Kiinamyllynkatu 4 8, 20520 Turku, Finland
Circulation 116:1032-40. 2007..The aims of the present study were to evaluate the effect of low-saturated-fat, low-cholesterol dietary counseling on fat intakes, growth, serum cholesterol values, and pubertal development in children and adolescents...
Left ventricular mass and geometry in adolescence: early childhood determinantsHanna Hietalampi
University of Turku, Research Centre of Applied and Preventive Cardiovascular Medicine, Kiinamyllynkatu 10, FI 20520 Turku, Finland
Hypertension 60:1266-72. 2012..0003), were associated with higher body mass index. Our results indicate that birth weight has a long-lasting impact on LVM and normal body weight is beneficial for cardiac structure in adolescents...
Effect of repeated dietary counseling on serum lipoproteins from infancy to adulthoodHarri Niinikoski
Department of Pediatrics, University of Turku and Turku University Hospital, Turku, Finland
Pediatrics 129:e704-13. 2012..Our aim was to study the influences of repeated low saturated fat dietary counseling on dietary intakes and lipoprotein measures from infancy to adulthood...
Carbohydrate intake, serum lipids and apolipoprotein E phenotype show association in childrenSoile Ruottinen
Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland
Acta Paediatr 98:1667-73. 2009..To study the association between carbohydrate intake and serum lipids in children, and influence of apolipoprotein E phenotype (apoE) on the association...
Effects of a home-based exercise program on metabolic risk factors and fitness in long-term survivors of childhood acute lymphoblastic leukemiaLiisa S Järvelä
Department of Pediatrics, Turku University Hospital, Turku, Finland
Pediatr Blood Cancer 59:155-60. 2012..The purpose of this study was to evaluate the effects of a simple, inexpensive home-based exercise program on cardiometabolic risk factors and fitness in long-term ALL survivors...
High sucrose intake is associated with poor quality of diet and growth between 13 months and 9 years of age: the special Turku Coronary Risk Factor Intervention ProjectSoile Ruottinen
Research Center of Applied and Preventive Cardiovascular Medicine, University of Turku, Kiinamyllynkatu 10, FI 20520 Turku, Finland
Pediatrics 121:e1676-85. 2008..Previous studies have suggested that interventions to lower dietary fat content and improved fat quality lead to a compensatory increase in sucrose content...
Endothelial function in healthy 11-year-old children after dietary intervention with onset in infancy: the Special Turku Coronary Risk Factor Intervention Project for children (STRIP)Olli T Raitakari
Department of Clinical Physiology, University of Turku, Turku, Finland
Circulation 112:3786-94. 2005..Early childhood introduction of nutritional habits aimed at atherosclerosis prevention reduces children's serum total cholesterol concentration, but its effect on vascular endothelial function is unknown...
Carnitine deficiency and L-carnitine supplementation in lysinuric protein intoleranceLaura M Tanner
Department of Pediatrics, University of Turku, 20520 Turku, Finland
Metabolism 57:549-54. 2008..Furthermore, decreased ratio of free and total serum carnitine was common even in LPI patients with normal total serum carnitine concentration...
Dietary patterns and nutrient intakes of 7-year-old children taking part in an atherosclerosis prevention project in FinlandMinna Räsänen
Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Finland
J Am Diet Assoc 102:518-24. 2002..To evaluate the dietary patterns of 7-year-old children participating in an atherosclerosis prevention project and the relationship of those dietary patterns to nutrient intakes and serum cholesterol values...
Nutrient intake, weight, and Leu7Pro polymorphism in prepro-neuropeptide Y in childrenMatti K Karvonen
Department of Neurology, University of Turku, 20520 Turku, Finland
J Clin Endocrinol Metab 91:4664-8. 2006..Pro7 substitution has been associated with the following: plasma NPY concentration, the risk factors of cardiovascular disease, birth weight of children, serum triglyceride concentration, and the function of vascular endothelium...
Nephropathy advancing to end-stage renal disease: a novel complication of lysinuric protein intoleranceLaura M Tanner
Department of Pediatrics, University of Turku, Turku, Finland
J Pediatr 150:631-4, 634.e1. 2007..To analyze systemically the prevalence of renal involvement in a cohort of Finnish patients with lysinuric protein intolerance (LPI) and to describe the course and outcome of end-stage renal disease in 4 patients...
The initiatives and outcomes for cardiovascular risks that can be achieved through paediatric counsellingJorma Viikari
Department of Medicine, University of Turku, Turku, Finland
Curr Opin Lipidol 20:17-23. 2009..Dietary patterns have a central role in the development of coronary heart disease through effects on serum lipids and development of body fatness. It is the purpose of this review to describe progress in this field...
Growth patterns and obesity development in overweight or normal-weight 13-year-old adolescents: the STRIP studyHanna Lagström
Turku Institute for Child and Youth Research, Turku, Finland
Pediatrics 122:e876-83. 2008..Our goal was to study childhood growth patterns and development of overweight in children who were overweight or normal weight at 13 years of age...
Association of physical activity with vascular endothelial function and intima-media thicknessKatja Pahkala
University of Turku, Research Centre of Applied and Preventive Cardiovascular Medicine, FI 20520 Turku, Finland
Circulation 124:1956-63. 2011..We investigated prospectively the association of leisure-time physical activity with endothelial function (brachial artery flow-mediated dilatation; FMD) and aortic IMT in adolescents...
Hazards associated with pregnancies and deliveries in lysinuric protein intoleranceLaura Tanner
Department of Pediatrics, University of Turku, 20520 Turku, Finland
Metabolism 55:224-31. 2006..We propose centralization of deliveries to obstetric units with capability to deal with bleeding complications and rare inborn errors of metabolism...
When and how to start prevention of atherosclerosis? Lessons from the Cardiovascular Risk in the Young Finns Study and the Special Turku Coronary Risk Factor Intervention ProjectCostan G Magnussen
Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku and Turku University Hospital, Kiinamyllynkatu 10, 20520, Finland, Finland
Pediatr Nephrol 27:1441-52. 2012....
Long-term oral lysine supplementation in lysinuric protein intoleranceLaura M Tanner
Department of Pediatrics, University of Turku, 20520 Turku, Finland
Metabolism 56:185-9. 2007..In conclusion, low-dose oral lysine supplementation is potentially beneficial to patients with LPI and can be started safely at an early age...
Exploring the transcriptomic variation caused by the Finnish founder mutation of lysinuric protein intolerance (LPI)Maaria Tringham
Department of Medical Biochemistry and Genetics, University of Turku, Kiinamyllynkatu 10, 20520 Turku, Finland
Mol Genet Metab 105:408-15. 2012..We conclude that changes in the expression of genes other than SLC7A7 may be linked to the various symptoms of LPI, indicating a complex interplay between amino acid transporters and various cellular processes...
Genitopatellar syndrome in an adolescent female with severe osteoporosis and endocrine abnormalitiesMaila Penttinen
Clinical Genetics Unit, Department of Pediatrics, Turku University Hospital, Turku, Finland
Am J Med Genet A 149:451-5. 2009..We suggest that these novel findings are also manifestations of GPS...
Case 2: Two young children with polydipsia, polyuria and severe hypertensionTimo Jahnukainen
Department of Paediatrics, Turku University Hospital, Turku, Finland
Acta Paediatr 95:881-3; discussion 884-5. 2006
Physical activity and fitness in adolescent and young adult long-term survivors of childhood acute lymphoblastic leukaemiaLiisa S Järvelä
Department of Paediatrics, Turku University Hospital, Kiinamyllynkatu 4 8, FI 20520, Turku, Finland
J Cancer Surviv 4:339-45. 2010..There is a lack of data on physical activity (PA) and fitness of adolescent and young adult very long-term survivors of childhood acute lymphoblastic leukemia (ALL)...
[Phenylketonuria]Harri Niinikoski
TYKS n lastenklinikka, Kiinamyllynkatu 4 8, 20520 Turku
Duodecim 125:1069-75. 2009..A newborn affected with phenylketonuria is asymptomatic but will rapidly become disabled without therapy. The leading principle of the therapy is careful limitation of phenylalanine intake...
Breast milk fatty acid composition differs between overweight and normal weight women: the STEPS StudyJohanna Mäkelä
Turku Institute for Child and Youth Research, University of Turku, Turku, Finland
Eur J Nutr 52:727-35. 2013..We studied differences in breast milk fatty acid (FA) composition between overweight and normal weight women and the effect of FA composition on children's cholesterol concentrations at 13 months and growth from birth to 13 months...
