L Maunula

Summary

Affiliation: University of Helsinki
Country: Finland

Publications

  1. ncbi Frequent reassortments may explain the genetic heterogeneity of rotaviruses: analysis of Finnish rotavirus strains
    Leena Maunula
    Division of Virology, HD Laboratories, Helsinki University Central Hospital, Helsinki, Finland
    J Virol 76:11793-800. 2002
  2. ncbi Presence of human noro- and adenoviruses in river and treated wastewater, a longitudinal study and method comparison
    Leena Maunula
    Department of Food Hygiene and Environmental Health, University of Helsinki, Finland
    J Water Health 10:87-99. 2012
  3. ncbi Short sequences define genetic lineages: phylogenetic analysis of group A rotaviruses based on partial sequences of genome segments 4 and 9
    L Maunula
    Department of Virology, Haartman Institute, University of Helsinki, Finland
    J Gen Virol 79:321-32. 1998
  4. ncbi Confirmation of Norwalk-like virus amplicons after RT-PCR by microplate hybridization and direct sequencing
    L Maunula
    Department of Virology, Haartman Institute, University of Helsinki, Finland
    J Virol Methods 83:125-34. 1999
  5. ncbi Norovirus outbreaks from drinking water
    Leena Maunula
    Department of Food and Environmental Hygiene, Faculty of Veterinary Medicine, HUCH Laboratory Diagnostics, University of Helsinki, 00014 Helsinki, Finland
    Emerg Infect Dis 11:1716-21. 2005
  6. ncbi Norovirus genotypes causing gastroenteritis outbreaks in Finland 1998-2002
    L Maunula
    HUCH Laboratory Diagnostics, Division of Virology, Haartmaninkatu 3, 00290 Helsinki, Finland
    J Clin Virol 34:186-94. 2005
  7. ncbi Outbreak of viral gastroenteritis due to drinking water contaminated by Norwalk-like viruses
    M Kukkula
    Department of Virology, Haartman Institute, University of Helsinki, FIN 00014 Helsinki, Finland
    J Infect Dis 180:1771-6. 1999
  8. ncbi Wading pool water contaminated with both noroviruses and astroviruses as the source of a gastroenteritis outbreak
    L Maunula
    HUCH Laboratory Diagnostics, Division of Virology, Haartmaninkatu, Helsinki, Finland
    Epidemiol Infect 132:737-43. 2004
  9. ncbi Potential internalisation of caliciviruses in lettuce
    A Urbanucci
    Department of Food and Environmental Hygiene, University of Helsinki, Finland
    Int J Food Microbiol 135:175-8. 2009
  10. ncbi Rotavirus serotypes and electropherotypes in Finland from 1986 to 1990
    L Maunula
    Haartman Institute, Department of Virology, University of Helsinki, Finland
    Arch Virol 140:877-90. 1995

Collaborators

Detail Information

Publications20

  1. ncbi Frequent reassortments may explain the genetic heterogeneity of rotaviruses: analysis of Finnish rotavirus strains
    Leena Maunula
    Division of Virology, HD Laboratories, Helsinki University Central Hospital, Helsinki, Finland
    J Virol 76:11793-800. 2002
    ..The extensive genetic diversity and number of e-types among rotaviruses are best explained by frequent genetic reassortment...
  2. ncbi Presence of human noro- and adenoviruses in river and treated wastewater, a longitudinal study and method comparison
    Leena Maunula
    Department of Food Hygiene and Environmental Health, University of Helsinki, Finland
    J Water Health 10:87-99. 2012
    ..64 × 10(3) and 1.29 × 10(4) pcr units per mL, respectively. No correlation between the presence of viruses and Escherichia coli was found. These results may be useful for risk assessment studies...
  3. ncbi Short sequences define genetic lineages: phylogenetic analysis of group A rotaviruses based on partial sequences of genome segments 4 and 9
    L Maunula
    Department of Virology, Haartman Institute, University of Helsinki, Finland
    J Gen Virol 79:321-32. 1998
    ..These amino acid signature motifs were located in aa 29-68 of VP7 and aa 121-135 of VP4 of the G1 and P[8] lineages, respectively...
  4. ncbi Confirmation of Norwalk-like virus amplicons after RT-PCR by microplate hybridization and direct sequencing
    L Maunula
    Department of Virology, Haartman Institute, University of Helsinki, Finland
    J Virol Methods 83:125-34. 1999
    ..Based on the sequences three more probes for the hybridization panel were added so that all the different NLVs of this study could be recognized...
  5. ncbi Norovirus outbreaks from drinking water
    Leena Maunula
    Department of Food and Environmental Hygiene, Faculty of Veterinary Medicine, HUCH Laboratory Diagnostics, University of Helsinki, 00014 Helsinki, Finland
    Emerg Infect Dis 11:1716-21. 2005
    ..In all but 1 instance, the amplicon sequence was identical to that recovered from the patients. The ubiquity of waterborne norovirus outbreaks calls for measures to monitor water for viruses...
  6. ncbi Norovirus genotypes causing gastroenteritis outbreaks in Finland 1998-2002
    L Maunula
    HUCH Laboratory Diagnostics, Division of Virology, Haartmaninkatu 3, 00290 Helsinki, Finland
    J Clin Virol 34:186-94. 2005
    ..Outbreak investigation methods for enteric viruses were improved in 1990s when gene amplification techniques were established in viral laboratories...
  7. ncbi Outbreak of viral gastroenteritis due to drinking water contaminated by Norwalk-like viruses
    M Kukkula
    Department of Virology, Haartman Institute, University of Helsinki, FIN 00014 Helsinki, Finland
    J Infect Dis 180:1771-6. 1999
    ..In some patients, NLV genogroup I was also encountered. This virus, however, could not be detected in the water samples. Inadequate chlorination contributed to the survival of the virus in the water...
  8. ncbi Wading pool water contaminated with both noroviruses and astroviruses as the source of a gastroenteritis outbreak
    L Maunula
    HUCH Laboratory Diagnostics, Division of Virology, Haartmaninkatu, Helsinki, Finland
    Epidemiol Infect 132:737-43. 2004
    ..Here we show how molecular methods aided in tracing the source of the epidemic and in finding the causative pathogens both in patients and in the environment...
  9. ncbi Potential internalisation of caliciviruses in lettuce
    A Urbanucci
    Department of Food and Environmental Hygiene, University of Helsinki, Finland
    Int J Food Microbiol 135:175-8. 2009
    ..Based on these results, viral contamination of lettuce plants via roots cannot be excluded, but is apparently not an important transmission route for viruses...
  10. ncbi Rotavirus serotypes and electropherotypes in Finland from 1986 to 1990
    L Maunula
    Haartman Institute, Department of Virology, University of Helsinki, Finland
    Arch Virol 140:877-90. 1995
    ..Group C rotavirus was found in 8 specimens. In this study a shift in serotypes, from G1 to G4, was observed in Finland in 1988/89; a similar shift was reported in many European countries at that time...
  11. ncbi Hepatitis E virus in patients with unexplained hepatitis in Finland
    Tuija Kantala
    Department of Food and Environmental Hygiene, Faculty of Veterinary Medicine, P O Box 66, FI 00014 University of Helsinki, Finland
    J Clin Virol 45:109-13. 2009
    ..Recently, HEV isolates have been identified in humans also in industrialized countries, where it has been considered nonendemic...
  12. ncbi Applicability of microarray technique for the detection of noro- and astroviruses
    Anne J Jääskeläinen
    Department of Virology, Haartman Institute, University of Helsinki, FIN 00014 Helsinki, Finland
    J Virol Methods 136:210-6. 2006
    ..Microarray provides a convenient tool for the detection of RNA viruses for which frequent changes in the panel of detection primers may be required...
  13. ncbi Molecular epidemiology of viral pathogens and tracing of transmission routes: hepatitis-, calici- and hantaviruses
    M Lappalainen
    Department of Virology, HUCH Laboratory Diagnostics, Helsinki University Central Hospital Haartman Institute, Haartmaninkatu 3, 00290, Helsinki, Finland
    J Clin Virol 21:177-85. 2001
    ..Exceptional host-switch events allow a study on still radiating hantavirus species. There is suggestive evidence that natural reassortant hantaviruses are involved in human infection...
  14. ncbi Campylobacter spp., Giardia spp., Cryptosporidium spp., noroviruses, and indicator organisms in surface water in southwestern Finland, 2000-2001
    Ari Hörman
    Department of Food and Environmental Hygiene, Faculty of Veterinary Medicine, University of Helsinki, Helsinki, Finland
    Appl Environ Microbiol 70:87-95. 2004
    ..There were no significant correlations between counts or count levels for thermotolerant coliforms or E. coli or the presence of F-RNA phages and pathogens in the samples analyzed...
  15. ncbi International collaborative study to compare reverse transcriptase PCR assays for detection and genotyping of noroviruses
    Jan Vinje
    Research Laboratory for Infectious Diseases, National Institute of Public Health and the Environment, Bilthoven, The Netherlands
    J Clin Microbiol 41:1423-33. 2003
    ..To promote comparability of data, this assay will be recommended for newly starting groups in future collaborative studies...
  16. ncbi Emergence of new norovirus variants on spring cruise ships and prediction of winter epidemics
    Linda Verhoef
    Center for Infectious Disease Control, Bilthoven, The Netherlands
    Emerg Infect Dis 14:238-43. 2008
    ..Internationally accepted guidelines are needed for reporting, investigating, and controlling norovirus illness on cruise ships in Europe...
  17. ncbi Internet use and epidemiologic investigation of gastroenteritis outbreak
    Markku Kuusi
    Department of Infectious Disease Epidemiology, National Public Health Institute, Mannerheimintie 166, 000300 Helsinki, Finland
    Emerg Infect Dis 10:447-50. 2004
    ..However, methods should be developed to increase response rates and minimize bias...
  18. ncbi Increase in viral gastroenteritis outbreaks in Europe and epidemic spread of new norovirus variant
    Ben Lopman
    Health Protection Agency, London, UK
    Lancet 363:682-8. 2004
    ..In addition to showing the added value of an international network for viral gastroenteritis outbreaks, these observations raise questions about the biological properties of the variant and the mechanisms for its rapid dissemination...
  19. ncbi Round-robin comparison of methods for the detection of human enteric viruses in lettuce
    Francoise S Le Guyader
    IFREMER, Laboratoire de Microbiologie, BP 21105, 44311 Nantes Cedex 03, France
    J Food Prot 67:2315-9. 2004
    ..Such development of sensitive methods for viral detection in foods other than shellfish is important to improve food safety...
  20. ncbi Survival of Mycobacterium avium, Legionella pneumophila, Escherichia coli, and caliciviruses in drinking water-associated biofilms grown under high-shear turbulent flow
    Markku J Lehtola
    Environmental Microbiology Laboratory, National Public Health Institute, Department of Environmental Health, P O Box 95, FI 70701 Kuopio, Finland
    Appl Environ Microbiol 73:2854-9. 2007
    ..Also, considering the low number of virus particles needed to result in an infection, their extended survival in biofilms must be taken into account as a risk for the consumer...