P K Maasilta

Summary

Affiliation: University of Helsinki
Country: Finland

Publications

  1. pmc Ingraft chimerism in lung transplantation--a study in a porcine model of obliterative bronchiolitis
    Outi E Päiväniemi
    Department of Cardiothoracic Surgery, Helsinki University Hospital, University of Helsinki, P O Box 340, 00029 HUS, Helsinki, Finland
    Respir Res 12:56. 2011
  2. ncbi request reprint Obliterative airway disease in a porcine heterotopic bronchial allograft model
    P Maasilta
    Department of Medicine, University of Helsinki, Helsinki University Central Hospital, Finland
    Transpl Int 13:218-24. 2000
  3. ncbi request reprint Immune cells in a heterotopic lamb-to-pig bronchial xenograft model
    Paula K Maasilta
    Department of Surgery, Helsinki University Hospital, HUS, Finland
    Transpl Int 18:1100-8. 2005
  4. ncbi request reprint Mortality from amyotrophic lateral sclerosis in Finland, 1986-1995
    P Maasilta
    Department of Pulmonary Medicine, Helsinki University Central Hospital, Helsinki, Finland
    Acta Neurol Scand 104:232-5. 2001
  5. ncbi request reprint Sleep-related disordered breathing during pregnancy in obese women
    P Maasilta
    Department of Pulmonary Medicine, Helsinki University Hospital, Helsinki, Finland
    Chest 120:1448-54. 2001
  6. ncbi request reprint Prevention of small airway obliteration in a swine heterotopic lung allograft model
    U S Salminen
    Department of Surgery, Helsinki University Central Hospital, Finland
    J Heart Lung Transplant 19:193-206. 2000
  7. ncbi request reprint Immune cells and immunosuppression in a porcine bronchial model of obliterative bronchiolitis
    P K Maasilta
    Department of Pulmonary Medicine, University of Helsinki, Finland
    Transplantation 72:998-1005. 2001
  8. ncbi request reprint Collagens I and III in a porcine bronchial model of obliterative bronchiolitis
    H S Alho
    Department of Surgery, Helsinki University Hospital, Helsinki, Finland
    Am J Respir Crit Care Med 164:1519-25. 2001
  9. ncbi request reprint Nitric oxide in the development of obliterative bronchiolitis in a heterotopic pig model
    Ulla Stina Salminen
    Tissue Engineering Centre, Imperial College School of Medicine, Chelsea and Westminster Hospital, London, UK
    Transplantation 73:1724-9. 2002
  10. ncbi request reprint Epithelial apoptosis in experimental obliterative airway disease after lung transplantation
    Hanni S Alho
    Department of Surgery, Helsinki University Hospital, Helsinki, Finland
    J Heart Lung Transplant 22:1014-22. 2003

Collaborators

Detail Information

Publications15

  1. pmc Ingraft chimerism in lung transplantation--a study in a porcine model of obliterative bronchiolitis
    Outi E Päiväniemi
    Department of Cardiothoracic Surgery, Helsinki University Hospital, University of Helsinki, P O Box 340, 00029 HUS, Helsinki, Finland
    Respir Res 12:56. 2011
    ..Herein we study the influence of chimerism on bronchial epithelium and OB development in pigs...
  2. ncbi request reprint Obliterative airway disease in a porcine heterotopic bronchial allograft model
    P Maasilta
    Department of Medicine, University of Helsinki, Helsinki University Central Hospital, Finland
    Transpl Int 13:218-24. 2000
    ..The obliterative lesions histologically resembled human OB. Differences from our previous findings with terminal bronchioles were minor. This study supports the use of larger-size airways in the study of OB...
  3. ncbi request reprint Immune cells in a heterotopic lamb-to-pig bronchial xenograft model
    Paula K Maasilta
    Department of Surgery, Helsinki University Hospital, HUS, Finland
    Transpl Int 18:1100-8. 2005
    ..The combination of CsA and everolimus was able to blunt the response and delay the subsequent obliteration...
  4. ncbi request reprint Mortality from amyotrophic lateral sclerosis in Finland, 1986-1995
    P Maasilta
    Department of Pulmonary Medicine, Helsinki University Central Hospital, Helsinki, Finland
    Acta Neurol Scand 104:232-5. 2001
    ..To study the possible changes, between 1986 and 1995, in the mortality due to amyotrophic lateral sclerosis (ALS) among Finnish patients...
  5. ncbi request reprint Sleep-related disordered breathing during pregnancy in obese women
    P Maasilta
    Department of Pulmonary Medicine, Helsinki University Hospital, Helsinki, Finland
    Chest 120:1448-54. 2001
    ..Obesity is known to predispose to sleep-related breathing disorders. During pregnancy, obese mothers gain additional weight, but other mechanisms may counteract this effect...
  6. ncbi request reprint Prevention of small airway obliteration in a swine heterotopic lung allograft model
    U S Salminen
    Department of Surgery, Helsinki University Central Hospital, Finland
    J Heart Lung Transplant 19:193-206. 2000
    ..This regimen includes the novel macrolide SDZ RAD, i.e., 40-O-(2hydroxyethyl)-rapamycin...
  7. ncbi request reprint Immune cells and immunosuppression in a porcine bronchial model of obliterative bronchiolitis
    P K Maasilta
    Department of Pulmonary Medicine, University of Helsinki, Finland
    Transplantation 72:998-1005. 2001
    ..These results support OB being T-cell mediated. RAD may have additional important effects on growth factors and proliferation in prevention of OB...
  8. ncbi request reprint Collagens I and III in a porcine bronchial model of obliterative bronchiolitis
    H S Alho
    Department of Surgery, Helsinki University Hospital, Helsinki, Finland
    Am J Respir Crit Care Med 164:1519-25. 2001
    ..This finding suggests a positive association between type III collagen mRNA expression in fibroblast-like cells and development of obliterative bronchiolitis...
  9. ncbi request reprint Nitric oxide in the development of obliterative bronchiolitis in a heterotopic pig model
    Ulla Stina Salminen
    Tissue Engineering Centre, Imperial College School of Medicine, Chelsea and Westminster Hospital, London, UK
    Transplantation 73:1724-9. 2002
    ..To elucidate the role of NO in this cascade, heterotopic bronchial allografts were studied in pigs...
  10. ncbi request reprint Epithelial apoptosis in experimental obliterative airway disease after lung transplantation
    Hanni S Alho
    Department of Surgery, Helsinki University Hospital, Helsinki, Finland
    J Heart Lung Transplant 22:1014-22. 2003
    ..Epithelial damage is an important feature in the pathogenesis of obliterative airway disease. We investigated the extent of epithelial apoptosis in this process in pig bronchial allografts...
  11. ncbi request reprint Cyclooxygenase-2 expression in experimental post-transplant obliterative bronchiolitis
    Outi E Päiväniemi
    Department of Surgery, Helsinki University Hospital, Finland
    J Pathol 204:340-8. 2004
    ..In addition, the observation that COX-2 expression in macrophages and fibroblasts paralleled the onset of inflammation and fibroblast proliferation indicates a role in OB development, but the causal relationships need further study...
  12. ncbi request reprint Matrix metalloproteinase induction in post-transplant obliterative bronchiolitis
    Leena M Eerola
    Department of Surgery, Helsinki University Hospital, Helsinki, Finland
    J Heart Lung Transplant 24:426-32. 2005
    ..Proteolytic enzymes such as the matrix metalloproteinases mediate degradation. To assess matrix metalloproteinases during obliterative bronchiolitis development, we studied porcine, heterotopic bronchial allografts...
  13. ncbi request reprint Platelet-derived growth factor, transforming growth factor-beta, and connective tissue growth factor in a porcine bronchial model of obliterative bronchiolitis
    Hanni S Alho
    Department of Surgery, Helsinki University Hospital, Helsinki, Finland
    Exp Lung Res 33:303-20. 2007
    ..This study further confirms PDGF and TGF-beta as mediators of OB and supports the concept of the importance of the pathways signaled through PDGF receptors in post-transplant OB...
  14. doi request reprint Epithelial tenascin predicts obliterative airway disease
    Outi E Päiväniemi
    Department of Cardiothoracic Surgery, Helsinki University Hospital, Helsinki, Finland
    J Heart Lung Transplant 27:400-7. 2008
    ..Tenascin as an extracellular matrix glycoprotein is expressed in several remodeling processes...
  15. ncbi request reprint Tumor necrosis factor-alpha in a porcine bronchial model of obliterative bronchiolitis
    Hanni S Alho
    Department of Surgery, Helsinki University Hospital, Helsinki, Finland
    Transplantation 76:516-23. 2003
    ..We assessed the role of TNF-alpha in the development of OB in our heterotopic porcine bronchial transplantation model...