Heikki P Lukkarinen

Summary

Affiliation: University of Turku
Country: Finland

Publications

  1. request reprint
    Lukkarinen H, Laine J, Aho H, Zagariya A, Vidyasagar D, Kaapa P. Angiotensin II receptor inhibition prevents pneumocyte apoptosis in surfactant-depleted rat lungs. Pediatr Pulmonol. 2005;39:349-58 pubmed
    ..The results suggest that increased epithelial apoptosis in surfactant-deficient lungs is mediated by ANG II receptor (specifically, subtype 1) action. ..
  2. request reprint
    Lukkarinen H, Laine J, Aho H, Asikainen E, Penttinen P, Kääpä P. Inhibition of COX-2 aggravates neutrophil migration and pneumocyte apoptosis in surfactant-depleted rat lungs. Pediatr Res. 2006;59:412-7 pubmed
    ..These results suggest that specific inhibitors of COX-2 should be used cautiously in association with surfactant-deficient lung injuries. ..
  3. Lukkarinen H, Hogmalm A, Lappalainen U, Bry K. Matrix metalloproteinase-9 deficiency worsens lung injury in a model of bronchopulmonary dysplasia. Am J Respir Cell Mol Biol. 2009;41:59-68 pubmed publisher
    ..These results suggest that MMP-9 activity in the inflamed neonatal lung protects the lung against injury. ..
  4. Lukkarinen H, Eerola E, Ruohola A, Vainionpaa R, Jalava J, Kotila S, et al. Clostridium difficile ribotype 027-associated disease in children with norovirus infection. Pediatr Infect Dis J. 2009;28:847-8 pubmed publisher
    ..Viral gastroenteritis may contribute to epithelial homeostasis of the intestine and exacerbate the effects of toxins produced by C. difficile ribotype 027. ..

Detail Information

Publications4

  1. request reprint
    Lukkarinen H, Laine J, Aho H, Zagariya A, Vidyasagar D, Kaapa P. Angiotensin II receptor inhibition prevents pneumocyte apoptosis in surfactant-depleted rat lungs. Pediatr Pulmonol. 2005;39:349-58 pubmed
    ..The results suggest that increased epithelial apoptosis in surfactant-deficient lungs is mediated by ANG II receptor (specifically, subtype 1) action. ..
  2. request reprint
    Lukkarinen H, Laine J, Aho H, Asikainen E, Penttinen P, Kääpä P. Inhibition of COX-2 aggravates neutrophil migration and pneumocyte apoptosis in surfactant-depleted rat lungs. Pediatr Res. 2006;59:412-7 pubmed
    ..These results suggest that specific inhibitors of COX-2 should be used cautiously in association with surfactant-deficient lung injuries. ..
  3. Lukkarinen H, Hogmalm A, Lappalainen U, Bry K. Matrix metalloproteinase-9 deficiency worsens lung injury in a model of bronchopulmonary dysplasia. Am J Respir Cell Mol Biol. 2009;41:59-68 pubmed publisher
    ..These results suggest that MMP-9 activity in the inflamed neonatal lung protects the lung against injury. ..
  4. Lukkarinen H, Eerola E, Ruohola A, Vainionpaa R, Jalava J, Kotila S, et al. Clostridium difficile ribotype 027-associated disease in children with norovirus infection. Pediatr Infect Dis J. 2009;28:847-8 pubmed publisher
    ..Viral gastroenteritis may contribute to epithelial homeostasis of the intestine and exacerbate the effects of toxins produced by C. difficile ribotype 027. ..