Affiliation: University of Turku
- Generation of bioluminescent Streptococcus mutans and its usage in rapid analysis of the efficacy of antimicrobial compoundsV Loimaranta
Institute of Dentistry and Turku Immunology Centre, University of Turku, FIN 20520 Turku, Finland
Antimicrob Agents Chemother 42:1906-10. 1998..Thus, the light emission was found to be a reliable, sensitive, and real-time indicator of the bacteriostatic actions of the antimicrobial agents tested...
- Effects of bovine immune and non-immune whey preparations on the composition and pH response of human dental plaqueV Loimaranta
Institute of Dentistry and Turku Immunology Centre, University of Turku, Finland
Eur J Oral Sci 107:244-50. 1999..Thus, the short term rinsing indicates favourable effects of bovine immune whey on human dental plaque...
- Leucine-rich repeats of bacterial surface proteins serve as common pattern recognition motifs of human scavenger receptor gp340Vuokko Loimaranta
Departments of Medical Biochemistry and Genetics, Institute of Dentistry, University of Turku, Kiinamyllynkatu 10, FI 20520 Turku, Finland
J Biol Chem 284:18614-23. 2009..These results thus suggest that the conserved Lrr motif in bacterial proteins serves as a novel pattern recognition motif for unique core peptides of human scavenger receptor gp340...
- Identification of a novel streptococcal adhesin P (SadP) protein recognizing galactosyl-α1-4-galactose-containing glycoconjugates: convergent evolution of bacterial pathogens to binding of the same host receptorAnnika Kouki
Department of Medical Biochemistry and Genetics, University of Turku, Kiinamyllynkatu 10, Turku FI 20520, Finland
J Biol Chem 286:38854-64. 2011..coli verotoxin or Pseudomonas aeruginosa lectin I also recognizing the same Galα1-4Gal disaccharide. The SadP and E. coli P adhesins represent a unique example of convergent evolution toward binding to the same host receptor structure...
- Sensitivity of Helicobacter pylori to an innate defence mechanism, the lactoperoxidase system, in buffer and in human whole salivaAnna Haukioja
Institute of Dentistry, University of Turku, Lemminkaisenkatu 2, FIN 20520 Turku, Finland
J Med Microbiol 53:855-60. 2004..Thus, further studies are needed to enhance the efficacy of peroxidase systems in human saliva to make it more beneficial not only against dental but also against gastric pathogens...
- Construction of antibody mimics from a noncatalytic enzyme-detection of polysialic acidAnne Jokilammi
Department of Medical Biochemistry and Molecular Biology, University of Turku, Kiinamyllynkatu 10, FI 20520 Turku, Finland
J Immunol Methods 295:149-60. 2004..Some of these could be used in designing well-defined substitute antibodies for the study of target molecules which are difficult to purify, available in low quantities, are unstable or have poor immunogenity...
- Decorin binding by DbpA and B of Borrelia garinii, Borrelia afzelii, and Borrelia burgdorferi sensu StrictoJemiina Salo
Department of Medical Microbiology and Immunology, University of Turku, Kiinamyllynkatu 13, Turku, Finland
J Infect Dis 204:65-73. 2011..DbpA and B of Borrelia garinii, Borrelia afzelii, and Borrelia burgdorferi sensu stricto (ss) differ in their amino acid sequence, but little attention has been paid to the potential difference in their decorin binding...
- Origin, structure, and biological activities of peroxidases in human salivaRiikka Ihalin
Department of Cariology, Institute of Dentistry, University of Turku, Lemminkaisenkatu 2, FIN 20520 Turku, Finland
Arch Biochem Biophys 445:261-8. 2006..Although being target of an active antimicrobial research, the structure-function relationships of hSPO are poorly known. However, recently published method for recombinant hSPO production offers new tools for those investigations...
- Lactoperoxidase inhibits glucosyltransferases from Streptococcus mutans in vitroA Korpela
Department of Cariology, Institute of Dentistry, University of Turku, Finland
Caries Res 36:116-21. 2002..This study shows that the lactoperoxidase system can exert inhibitory activity against streptococcal Gtfs without generating oxidizing agents...
- Oral adhesion and survival of probiotic and other lactobacilli and bifidobacteria in vitroA Haukioja
Institute of Dentistry, University of Turku, Turku, Finland
Oral Microbiol Immunol 21:326-32. 2006..Our aim was to evaluate the oral colonization potential of different probiotic, dairy, and fecal Lactobacillus and Bifidobacterium strains in vitro...
- Probiotic bacteria affect the composition of salivary pellicle and streptococcal adhesion in vitroA Haukioja
Postgraduate School of Oral Health Sciences, Institute of Dentistry, Universeity of Turku, Turku, Finland
Oral Microbiol Immunol 23:336-43. 2008..The aim of this study was to investigate in vitro if the probiotic bacteria used in commercial products affect the protein composition of the salivary pellicle and the adherence of other oral bacteria...
- Stability and activity of specific antibodies against Streptococcus mutans and Streptococcus sobrinus in bovine milk fermented with Lactobacillus rhamnosus strain GG or treated at ultra-high temperatureH Wei
Agrifood Research Finland, Food Research, Jokioinen, Finland
Oral Microbiol Immunol 17:9-15. 2002..From the anticariogenic point of view it may be beneficial to add bovine-specific antibodies against mutans streptococci to probiotic LGG-containing milk products...
- Fluid- or surface-phase human salivary scavenger protein gp340 exposes different bacterial recognition propertiesV Loimaranta
Department of Odontology Cariology, Umea University, SE 901 87 Umea, Sweden
Infect Immun 73:2245-52. 2005..This phase-associated differential recognition by gp340 of streptococcal species of different levels of virulence and diverse origins may mediate alternative host responses to commensal or pathogenic bacterial phenotypes...