M K Lindström

Summary

Affiliation: University of Helsinki
Country: Finland

Publications

  1. pmc Involvement of two-component system CBO0366/CBO0365 in the cold shock response and growth of group I (proteolytic) Clostridium botulinum ATCC 3502 at low temperatures
    Miia Lindstrom
    Department of Food Hygiene and Environmental Health, University of Helsinki, Helsinki, Finland
    Appl Environ Microbiol 78:5466-70. 2012
  2. pmc Involvement of Clostridium botulinum ATCC 3502 sigma factor K in early-stage sporulation
    David G Kirk
    Department of Food Hygiene and Environmental Health, Centre of Excellence in Microbial Food Safety Research, Faculty of Veterinary Medicine, University of Helsinki, Finland
    Appl Environ Microbiol 78:4590-6. 2012
  3. doi request reprint Novel insights into the epidemiology of Clostridium perfringens type A food poisoning
    Miia Lindstrom
    Department of Food Hygiene and Environmental Health, Centre of Excellence in Microbial Food Safety Research, Faculty of Veterinary Medicine, P O Box 66, 00014 University of Helsinki, Finland
    Food Microbiol 28:192-8. 2011
  4. doi request reprint Clostridium botulinum in cattle and dairy products
    Miia Lindstrom
    Department of Food and Environmental Hygiene, Faculty of Veterinary Medicine, University of Helsinki, Finland
    Crit Rev Food Sci Nutr 50:281-304. 2010
  5. pmc Comparative genomic hybridization analysis of two predominant Nordic group I (proteolytic) Clostridium botulinum type B clusters
    Miia Lindstrom
    Department of Food and Environmental Hygiene, Faculty of Veterinary Medicine, University of Helsinki, P O Box 66, 00014 Helsinki University, Finland
    Appl Environ Microbiol 75:2643-51. 2009
  6. ncbi request reprint Identification of Clostridium botulinum with API 20 A, Rapid ID 32 A and RapID ANA II
    M K Lindström
    Department of Food and Environmental Hygiene, University of Helsinki, Finland
    FEMS Immunol Med Microbiol 24:267-74. 1999
  7. pmc Laboratory diagnostics of botulism
    Miia Lindstrom
    Department of Food and Environmental Hygiene, University of Helsinki, P O Box 66, 00014 University of Helsinki, Finland
    Clin Microbiol Rev 19:298-314. 2006
  8. ncbi request reprint Hazard and control of group II (non-proteolytic) Clostridium botulinum in modern food processing
    Miia Lindstrom
    Department of Food and Environmental Hygiene, Faculty of Veterinary Medicine, P O Box 66, 00014 University of Helsinki, Finland
    Int J Food Microbiol 108:92-104. 2006
  9. pmc Type C botulism due to toxic feed affecting 52,000 farmed foxes and minks in Finland
    Miia Lindstrom
    Department of Food and Environmental Hygiene, Faculty of Veterinary Medicine, University of Helsinki, Finland
    J Clin Microbiol 42:4718-25. 2004
  10. ncbi request reprint The prevalence of Clostridium botulinum in European river lamprey (Lampetra fluviatilis) in Finland
    Lauri O Merivirta
    Department of Food and Environmental Hygiene, Faculty of Veterinary Medicine, University of Helsinki, P O Box 66, FIN 00014, Finland
    Int J Food Microbiol 109:234-7. 2006

Detail Information

Publications29

  1. pmc Involvement of two-component system CBO0366/CBO0365 in the cold shock response and growth of group I (proteolytic) Clostridium botulinum ATCC 3502 at low temperatures
    Miia Lindstrom
    Department of Food Hygiene and Environmental Health, University of Helsinki, Helsinki, Finland
    Appl Environ Microbiol 78:5466-70. 2012
    ....
  2. pmc Involvement of Clostridium botulinum ATCC 3502 sigma factor K in early-stage sporulation
    David G Kirk
    Department of Food Hygiene and Environmental Health, Centre of Excellence in Microbial Food Safety Research, Faculty of Veterinary Medicine, University of Helsinki, Finland
    Appl Environ Microbiol 78:4590-6. 2012
    ..subtilis. Understanding the sporulation mechanism of C. botulinum provides keys to control the public health risks that the spores of this dangerous pathogen cause through foods...
  3. doi request reprint Novel insights into the epidemiology of Clostridium perfringens type A food poisoning
    Miia Lindstrom
    Department of Food Hygiene and Environmental Health, Centre of Excellence in Microbial Food Safety Research, Faculty of Veterinary Medicine, P O Box 66, 00014 University of Helsinki, Finland
    Food Microbiol 28:192-8. 2011
    ..perfringens food poisoning fail to detect and isolate many C. perfringens strains, distorting the epidemiological understanding of C. perfringens food poisoning...
  4. doi request reprint Clostridium botulinum in cattle and dairy products
    Miia Lindstrom
    Department of Food and Environmental Hygiene, Faculty of Veterinary Medicine, University of Helsinki, Finland
    Crit Rev Food Sci Nutr 50:281-304. 2010
    ....
  5. pmc Comparative genomic hybridization analysis of two predominant Nordic group I (proteolytic) Clostridium botulinum type B clusters
    Miia Lindstrom
    Department of Food and Environmental Hygiene, Faculty of Veterinary Medicine, University of Helsinki, P O Box 66, 00014 Helsinki University, Finland
    Appl Environ Microbiol 75:2643-51. 2009
    ..botulinum type B clusters present a public health hazard in Nordic countries. Knowing the genetic and physiological markers of these clusters will assist in targeting control measures against these pathogens...
  6. ncbi request reprint Identification of Clostridium botulinum with API 20 A, Rapid ID 32 A and RapID ANA II
    M K Lindström
    Department of Food and Environmental Hygiene, University of Helsinki, Finland
    FEMS Immunol Med Microbiol 24:267-74. 1999
    ..botulinum group II by the Rapid ID 32 A, 17 strains by the RapID ANA II, and one strain by the API 20 A. The results show that these test systems do not provide a reliable method for identification of C. botulinum...
  7. pmc Laboratory diagnostics of botulism
    Miia Lindstrom
    Department of Food and Environmental Hygiene, University of Helsinki, P O Box 66, 00014 University of Helsinki, Finland
    Clin Microbiol Rev 19:298-314. 2006
    ..Therefore, the toxin-producing organisms should be routinely isolated from the patient and the vehicle. The physiological group and genetic traits of the isolates should be determined...
  8. ncbi request reprint Hazard and control of group II (non-proteolytic) Clostridium botulinum in modern food processing
    Miia Lindstrom
    Department of Food and Environmental Hygiene, Faculty of Veterinary Medicine, P O Box 66, 00014 University of Helsinki, Finland
    Int J Food Microbiol 108:92-104. 2006
    ..This sets great challenges on the production of chilled packaged foods. To ensure the safety of these foods, more than one factor should safeguard against botulinal growth and toxin production...
  9. pmc Type C botulism due to toxic feed affecting 52,000 farmed foxes and minks in Finland
    Miia Lindstrom
    Department of Food and Environmental Hygiene, Faculty of Veterinary Medicine, University of Helsinki, Finland
    J Clin Microbiol 42:4718-25. 2004
    ..6 or below according to the manufacturer, it seems unlikely that spore germination and toxin formation occurred during overnight storage. Hence, the events leading to toxin formation were not determined...
  10. ncbi request reprint The prevalence of Clostridium botulinum in European river lamprey (Lampetra fluviatilis) in Finland
    Lauri O Merivirta
    Department of Food and Environmental Hygiene, Faculty of Veterinary Medicine, University of Helsinki, P O Box 66, FIN 00014, Finland
    Int J Food Microbiol 109:234-7. 2006
    ..To control the potential risk, a storage temperature of 3 degrees C or below should be recommended for these products...
  11. ncbi request reprint Proteolytic Clostridium botulinum type B in the gastric content of a patient with type E botulism due to whitefish eggs
    Miia Lindstrom
    Department of Food and Environmental Hygiene, University of Helsinki, Finland
    Foodborne Pathog Dis 1:53-7. 2004
    ..This is the first domestic case of foodborne botulism in Finland...
  12. doi request reprint PCR assay for differentiating between Group I (proteolytic) and Group II (nonproteolytic) strains of Clostridium botulinum
    Elias Dahlsten
    Department of Food and Environmental Hygiene, University of Helsinki, Helsinki, Finland
    Int J Food Microbiol 124:108-11. 2008
    ..botulinum is an essential step in investigation of human botulism outbreaks, and should be considered as a diagnostic corner-stone in order to improve our epidemiological understanding of human botulism...
  13. ncbi request reprint The detection and prevalence of Clostridium botulinum in pig intestinal samples
    Jan Myllykoski
    Department of Food and Environmental Hygiene, P O Box 66, 00014 University of Helsinki, Finland
    Int J Food Microbiol 110:172-7. 2006
    ..C. botulinum was isolated from two PCR-positive samples and confirmed to be type B by PCR. Both isolates were shown to be proteolytic and thus to represent C. botulinum group I...
  14. pmc Elimination of botulinum neurotoxin (BoNT) type B from drinking water by small-scale (personal-use) water purification devices and detection of BoNT in water samples
    Ari Hörman
    Department of Food and Environmental Hygiene, Faculty of Veterinary Medicine, University of Helsinki, Finland
    Appl Environ Microbiol 71:1941-5. 2005
    ..3 log10 units). The rapid EIAs intended for the detection of BoNT from various types of samples failed to detect BoNT from aqueous samples containing an estimated concentration of BoNT of 396,000 ng/liter...
  15. pmc Infant botulism acquired from household dust presenting as sudden infant death syndrome
    Mari Nevas
    Department of Food and Environmental Hygiene, Faculty of Veterinary Medicine, University of Helsinki, P O Box 66, 00014 Helsinki University, Finland
    J Clin Microbiol 43:511-3. 2005
    ....
  16. ncbi request reprint High prevalence of Clostridium botulinum types A and B in honey samples detected by polymerase chain reaction
    Mari Nevas
    Department of Food and Environmental Hygiene, Faculty of Veterinary Medicine, University of Helsinki, Finland
    Int J Food Microbiol 72:45-52. 2002
    ..Strains of C. botulinum type A were isolated from 14 and type B from 2 of the 20 PCR-positive samples. This is the first report of type A spores of C. botulinum being detected and isolated in Fennoscandia...
  17. pmc Important role of class I heat shock genes hrcA and dnaK in the heat shock response and the response to pH and NaCl stress of group I Clostridium botulinum strain ATCC 3502
    Katja Selby
    Department of Food Hygiene and Environmental Health, Agnes Sjöberginkatu 2, 00014 Helsinki University, Finland
    Appl Environ Microbiol 77:2823-30. 2011
    ..botulinum under the stressful environmental conditions that may be encountered during food processing or growth in food products, in the mammalian intestine, or in wounds...
  18. pmc Thermal inactivation of nonproteolytic Clostridium botulinum type E spores in model fish media and in vacuum-packaged hot-smoked fish products
    Miia Lindstrom
    Department of Food and Environmental Hygiene, Faculty of Veterinary Medicine, University of Helsinki, PO Box 57, FIN 00014 Helsinki, Finland
    Appl Environ Microbiol 69:4029-36. 2003
    ..The sensory qualities of safely processed and more lightly processed whitefish were similar, while differences between the sensory qualities of safely processed and lightly processed rainbow trout were observed...
  19. ncbi request reprint Antibacterial efficiency of Finnish spice essential oils against pathogenic and spoilage bacteria
    Mari Nevas
    Department of Food and Environmental Hygiene, Faculty of Veterinary Medicine, 00014 University of Helsinki, Finland
    J Food Prot 67:199-202. 2004
    ..By gas chromatography-mass spectrometry analysis, differences were noted in the composition of oregano and thyme oils in comparison to previous reports...
  20. doi request reprint Adaptation of enteropathogenic Yersinia to low growth temperature
    Eveliina Palonen
    Department of Food and Environmental Hygiene, University of Helsinki, Finland
    Crit Rev Microbiol 36:54-67. 2010
    ..Understanding low temperature adaptation of psychrotrophs would help to control these pathogens. This review demonstrates that more studies on cold tolerance mechanisms of psychrotrophs are needed...
  21. doi request reprint Introducing scientific training into the veterinary curriculum of the University of Helsinki
    Hannu Korkeala
    Department of Food and Environmental Hygiene, Faculty of Veterinary Medicine, P O Box 66, 00014 University of Helsinki, Finland
    J Vet Med Educ 36:83-8. 2009
    ..It appears that organizing supervised research training within the veterinary curriculum increases veterinary students' interest in scientific work...
  22. ncbi request reprint Group I Clostridium botulinum strains show significant variation in growth at low and high temperatures
    Katja Hinderink
    Department of Food and Environmental Hygiene, Faculty of Veterinary Medicine, University of Helsinki, P O Box 66, 00014 Helsinki, Finland
    J Food Prot 72:375-83. 2009
    ..The significant variation between strains of group I C. botulinum may have an impact on inoculation studies and predictive modeling when assessing the safety of foods...
  23. pmc Enumeration and isolation of cpe-positive Clostridium perfringens spores from feces
    Annamari Heikinheimo
    Department of Food and Environmental Hygiene, Faculty of Veterinary Medicine, University of Helsinki, P O Box 66, FIN 00014 Helsinki University, Finland
    J Clin Microbiol 42:3992-7. 2004
    ..perfringens. The method also offers a new approach in the investigation of the epidemiology of cpe-positive C. perfringens strains...
  24. ncbi request reprint Prevalence and diversity of Clostridium botulinum types A, B, E and F in honey produced in the Nordic countries
    Mari Nevas
    Department of Food and Environmental Hygiene, Faculty of Veterinary Medicine, University of Helsinki, P O Box 66, 00014 Helsinki, Finland
    Int J Food Microbiol 105:145-51. 2005
    ..At a similarity level of 95%, four clusters were produced, three of which contained 20 of the 24 analysed strains. One of the clusters included isolates from both Denmark and Norway...
  25. pmc Humans as reservoir for enterotoxin gene--carrying Clostridium perfringens type A
    Annamari Heikinheimo
    University of Helsinki, Helsinki, Finland
    Emerg Infect Dis 12:1724-9. 2006
    ..The results also indicate that humans should be considered a risk factor for spread of C. perfringens type A food poisoning and that they are a possible source of contamination for C. perfringens type A food poisoning...
  26. pmc Diversity of proteolytic Clostridium botulinum strains, determined by a pulsed-field gel electrophoresis approach
    Mari Nevas
    Department of Food and Environmental Hygiene, Faculty of Veterinary Medicine, University of Helsinki, PO Box 66, 00014 Helsinki University, Finland
    Appl Environ Microbiol 71:1311-7. 2005
    ..botulinum types A and B. However, epidemiological conclusions based on PFGE data only should be made with discretion, since highly similar PFGE patterns were noticed, especially within the type B strains...
  27. ncbi request reprint Contamination routes of Clostridium botulinum in the honey production environment
    Mari Nevas
    Department of Food and Environmental Hygiene, PO Box 66, 00014 University of Helsinki, Helsinki, Finland
    Environ Microbiol 8:1085-94. 2006
    ..botulinum spores in honey could possibly be diminished by increasing hygienic level in honey production...
  28. pmc Quantitative real-time reverse transcription-PCR analysis reveals stable and prolonged neurotoxin cluster gene activity in a Clostridium botulinum type E strain at refrigeration temperature
    Ying Chen
    Centre of Excellence in Microbial Food Safety Research, Department of Food and Environmental Hygiene, Faculty of Veterinary Medicine, University of Helsinki, Finland
    Appl Environ Microbiol 74:6132-7. 2008
    ..In light of group II C. botulinum type E being a dangerous food-borne pathogen, these findings may be important in terms of the safety of refrigerated packaged foods of extended durability...
  29. pmc Sequencing the botulinum neurotoxin gene and related genes in Clostridium botulinum type E strains reveals orfx3 and a novel type E neurotoxin subtype
    Ying Chen
    Department of Food and Environmental Hygiene, P O Box 66, FIN 00014, University of Helsinki, Finland
    J Bacteriol 189:8643-50. 2007
    ..The amino acid sequence of the subtype E6 neurotoxin differed 3 to 6% from the other subtypes, suggesting that these subtype E6 neurotoxins may possess specific antigenic or functional properties...