Ruut M Laitio

Summary

Affiliation: University of Turku
Country: Finland

Publications

  1. pmc Pharmacokinetics of prolonged infusion of high-dose dexmedetomidine in critically ill patients
    Timo Iirola
    Department of Anaesthesiology, Intensive Care, Emergency Care and Pain Medicine, University of Turku and Turku University Hospital, PO Box 52, FI 20521 Turku, Finland
    Crit Care 15:R257. 2011
  2. pmc Highly variable pharmacokinetics of dexmedetomidine during intensive care: a case report
    Timo Iirola
    Department of Anaesthesiology, Intensive Care, Emergency Care and Pain Medicine, University of Turku and Turku University Hospital, FIN 20521, Turku, Finland
    J Med Case Reports 4:73. 2010
  3. ncbi request reprint Effects of xenon anesthesia on cerebral blood flow in humans: a positron emission tomography study
    Ruut M Laitio
    Turku PET Centre, Department of Anesthesiology and Intensive Care, Turku University Hospital, Finland
    Anesthesiology 106:1128-33. 2007
  4. ncbi request reprint Bispectral index, entropy, and quantitative electroencephalogram during single-agent xenon anesthesia
    Ruut M Laitio
    Turku Positron Emission Tomography PET Centre, and Department of Anesthesiology and Intensive Care, Turku University Hospital, Turku, Finland
    Anesthesiology 108:63-70. 2008
  5. doi request reprint The effects of xenon anesthesia on the relationship between cerebral glucose metabolism and blood flow in healthy subjects: a positron emission tomography study
    Ruut M Laitio
    Turku PET Centre, University of Turku, Finland
    Anesth Analg 108:593-600. 2009
  6. doi request reprint Xenon does not affect gamma-aminobutyric acid type A receptor binding in humans
    Elina Salmi
    Turku PET Centre, Turku, Finland
    Anesth Analg 106:129-34, table of contents. 2008
  7. doi request reprint Feasibility and cardiac safety of inhaled xenon in combination with therapeutic hypothermia following out-of-hospital cardiac arrest
    Olli J Arola
    Perioperative Services, Intensive Care Medicine and Pain Management, Turku University Hospital, University of Turku, Turku, Finland
    Crit Care Med 41:2116-24. 2013

Collaborators

  • Kaike K Kaisti
  • Sargo Aalto
  • Mikko Pietilä
  • Esa R Korpi
  • Timo Iirola
  • Klaus T Olkkola
  • Riku Aantaa
  • Olli J Arola
  • Harry Scheinin
  • Erkki Kentala
  • Elina Salmi
  • Juhani Airaksinen
  • Mervyn Maze
  • Juha Grönlund
  • Juha Perttilä
  • Risto O Roine
  • Antti Saraste
  • Timo T Laitio
  • Chris Garratt
  • Tuula Ahtola-Sätilä
  • Maria Lahtinen
  • Andrew Wighton
  • Mika Scheinin
  • Juha Pekka Kurvinen
  • Kjell Någren
  • Jaakko W Långsjö
  • Anu T Maksimow
  • Liisa Metsahonkala
  • Vesa Oikonen

Detail Information

Publications7

  1. pmc Pharmacokinetics of prolonged infusion of high-dose dexmedetomidine in critically ill patients
    Timo Iirola
    Department of Anaesthesiology, Intensive Care, Emergency Care and Pain Medicine, University of Turku and Turku University Hospital, PO Box 52, FI 20521 Turku, Finland
    Crit Care 15:R257. 2011
    ..Additionally, we wanted to quantify for the first time in humans the concentrations of H-3, a practically inactive metabolite of dexmedetomidine...
  2. pmc Highly variable pharmacokinetics of dexmedetomidine during intensive care: a case report
    Timo Iirola
    Department of Anaesthesiology, Intensive Care, Emergency Care and Pain Medicine, University of Turku and Turku University Hospital, FIN 20521, Turku, Finland
    J Med Case Reports 4:73. 2010
    ..There are some previous reports on the use of long-term moderate to high-dose infusions of dexmedetomidine in patients in intensive care units, but none of these accounts have cited dexmedetomidine plasma concentrations...
  3. ncbi request reprint Effects of xenon anesthesia on cerebral blood flow in humans: a positron emission tomography study
    Ruut M Laitio
    Turku PET Centre, Department of Anesthesiology and Intensive Care, Turku University Hospital, Finland
    Anesthesiology 106:1128-33. 2007
    ..Animal studies have demonstrated a strong neuroprotective property of xenon. Its usefulness in patients with cerebral pathology could be compromised by deleterious effects on regional cerebral blood flow (rCBF)...
  4. ncbi request reprint Bispectral index, entropy, and quantitative electroencephalogram during single-agent xenon anesthesia
    Ruut M Laitio
    Turku Positron Emission Tomography PET Centre, and Department of Anesthesiology and Intensive Care, Turku University Hospital, Turku, Finland
    Anesthesiology 108:63-70. 2008
    ..The aim was to evaluate the performance of anesthesia depth monitors, Bispectral Index (BIS) and Entropy, during single-agent xenon anesthesia in 17 healthy subjects...
  5. doi request reprint The effects of xenon anesthesia on the relationship between cerebral glucose metabolism and blood flow in healthy subjects: a positron emission tomography study
    Ruut M Laitio
    Turku PET Centre, University of Turku, Finland
    Anesth Analg 108:593-600. 2009
    ..In this positron emission tomography study, our aim was to assess both rCMR(glc) and rCBF in the same individuals during xenon anesthesia...
  6. doi request reprint Xenon does not affect gamma-aminobutyric acid type A receptor binding in humans
    Elina Salmi
    Turku PET Centre, Turku, Finland
    Anesth Analg 106:129-34, table of contents. 2008
    ..The mechanism of anesthetic action of xenon in the living human brain still remains to be determined...
  7. doi request reprint Feasibility and cardiac safety of inhaled xenon in combination with therapeutic hypothermia following out-of-hospital cardiac arrest
    Olli J Arola
    Perioperative Services, Intensive Care Medicine and Pain Management, Turku University Hospital, University of Turku, Turku, Finland
    Crit Care Med 41:2116-24. 2013
    ..The purpose of this study was to investigate the feasibility and cardiac safety of inhaled xenon treatment combined with therapeutic hypothermia in out-of-hospital cardiac arrest patients...