Research Topics
| T KujalaSummaryAffiliation: University of Helsinki Country: Finland Publications
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Detail Information
Publications
Electrophysiological evidence for cross-modal plasticity in humans with early- and late-onset blindnessT Kujala
Department of Psychology, University of Helsinki, Finland
Psychophysiology 34:213-6. 1997..These results suggest that cross-modal reorganization may occur even in the mature human brain...
The role of blind humans' visual cortex in auditory change detectionTeija Kujala
Helsinki Collegium for Advanced Studies, University of Helsinki, Finland
Neurosci Lett 379:127-31. 2005....
Auditory sensory memory disorder in dyslexic adults as indexed by the mismatch negativityT Kujala
Helsinki Collegium for Advanced Studies, and Finland Cognitive Brain Research Unit, Department of Psychology, P O Box 13, FIN 00014 University of Helsinki, Finland
Eur J Neurosci 17:1323-7. 2003..These results suggest impaired cortical discrimination of sounds and lowered tolerance for the masking effects of rapidly following sounds in dyslexia...
Evaluation of multi-attribute auditory discrimination in dyslexia with the mismatch negativityT Kujala
Helsinki Collegium for Advanced Studies, University of Helsinki, Helsinki, Finland
Clin Neurophysiol 117:885-93. 2006..We determined the discrimination of 5 sound contrasts (pitch, duration, intensity, location, and the presence of a gap) in dyslexia with the mismatch negativity (MMN)...
The mismatch negativity in cognitive and clinical neuroscience: theoretical and methodological considerationsTeija Kujala
Helsinki Collegium for Advanced Studies, University of Helsinki, FIN 00014 Helsinki, Finland
Biol Psychol 74:1-19. 2007..Thereafter, issues which need to be taken into account in MMN investigations as well as new improved recording paradigms are discussed...
Speech- and sound-segmentation in dyslexia: evidence for a multiple-level cortical impairmentT Kujala
Cognitive Brain Research Unit, Department of Psychology, University of Helsinki, PO Box 9, 00014 Helsinki, Finland
Eur J Neurosci 24:2420-7. 2006....
The mismatch negativity in evaluating central auditory dysfunction in dyslexiaT Kujala
Cognitive Brain Research Unit, Department of Psychology, University of Helsinki, P O Box 13, FIN 00014 Helsinki, Finland
Neurosci Biobehav Rev 25:535-43. 2001..Furthermore, the MMN holds promise of showing plastic changes in the brain of dyslexic individuals underlying the alleviation or remediation of dyslexia in the course of a successful training programme...
Plastic neural changes and reading improvement caused by audiovisual training in reading-impaired childrenT Kujala
Cognitive Brain Research Unit, Department of Psychology, P O Box 13, University of Helsinki, FIN 00014 Helsinki, Finland
Proc Natl Acad Sci U S A 98:10509-14. 2001..Moreover, the fact that the present training effects were obtained by using a program including no linguistic material indicates that dyslexia is at least partly based on a general auditory perceptual deficit...
The mismatch negativity as an index of temporal processing in auditionT Kujala
Cognitive Brain Research Unit, Department of Psychology, P O Box 13, University of Helsinki, FIN 00014 Helsinki, Finland
Clin Neurophysiol 112:1712-9. 2001..The relation of the mismatch negativity (MMN) elicitation with behavioral stimulus discrimination as well as the replicability of the MMN was evaluated for intervals between paired tones...
Atypical pattern of discriminating sound features in adults with Asperger syndrome as reflected by the mismatch negativityT Kujala
Cognitive Brain Research Unit, Department of Psychology, University of Helsinki, PO Box 9, Helsinki FIN 00014, Finland
Biol Psychol 75:109-14. 2007..Our results suggest hypersensitive auditory change detection in Asperger syndrome, as reflected in the enhanced MMN for deviant sounds with a gap or shorter duration, and speeded MMN elicitation for frequency changes...
Basic auditory dysfunction in dyslexia as demonstrated by brain activity measurementsT Kujala
Department of Psychology, University of Helsinki, Finland
Psychophysiology 37:262-6. 2000..This failure can be traced to early cortical mechanisms that process auditory information independently of attention...
Detrimental noise effects on brain's speech functionsTeija Kujala
Cognitive Brain Research Unit, Department of Psychology, University of Helsinki, Helsinki, Finland
Biol Psychol 81:135-43. 2009..These results both stress the importance to re-evaluate which noise levels can be considered safe for brain functions and raise concerns on the speech and cognitive abilities of individuals living in noisy environments...
The adaptive brain: a neurophysiological perspectiveTeija Kujala
Cognitive Brain Research Unit, Institute of Behavioural Sciences, University of Helsinki, Helsinki, Finland
Prog Neurobiol 91:55-67. 2010..They enable one to determine plastic neural changes even in patients who are unable to communicate and in infants learning a language...
Speech-feature discrimination in children with Asperger syndrome as determined with the multi-feature mismatch negativity paradigmT Kujala
Cognitive Brain Research Unit, Institute of Behavioural Sciences, University of Helsinki, P O Box 9, FIN 00014, Helsinki, Finland
Clin Neurophysiol 121:1410-9. 2010..Auditory processing involves both hyper- and hypoactive reactivity to acoustic changes...
Neurophysiological evidence for cortical discrimination impairment of prosody in Asperger syndromeT Kujala
Helsinki Collegium for Advanced Studies, University of Helsinki, Helsinki, Finland
Neurosci Lett 383:260-5. 2005..These findings were predominant over the right cerebral hemisphere. These results show impaired neurobiological basis for speech-prosody processing at an early, pre-attentive auditory discrimination stage in AS...
Auditory stream segregation in children with Asperger syndromeT Lepistö
Cognitive Brain Research Unit, Department of Psychology, University of Helsinki, P O Box 9, Helsinki FIN 00014, Finland
Biol Psychol 82:301-7. 2009..The results indicated that children with AS have difficulties in segregating concurrent sound streams, which ultimately may contribute to the difficulties in speech-in-noise perception...
The perception of invariant speech features in children with autismT Lepistö
Cognitive Brain Research Unit, Department of Psychology, University of Helsinki, P O Box 9, Helsinki FIN 00014, Finland
Biol Psychol 77:25-31. 2008..This suggests that children with autism lose their advantage in phoneme discrimination when the context of the stimuli is speech-like and requires abstracting invariant speech features from varying input...
The processing of sound duration after left hemisphere stroke: event-related potential and behavioral evidenceT M Ilvonen
Department of Psychology, University of Helsinki, Finland
Psychophysiology 38:622-8. 2001..Especially by recording MMN to monaural stimuli, the discrimination accuracy can be separately determined for the left and right temporal lobes...
Selective tuning of cortical sound-feature processing by language experienceM Tervaniemi
Cognitive Brain Research Unit, Department of Psychology, University of Helsinki, Finland
Eur J Neurosci 23:2538-41. 2006..This result, obtained both by behavioural and neural indices at attentive and automatic levels of processing, indicates precise feature-specific tuning of the auditory-cortex functions by the mother tongue...
Auditory perception and attention as reflected by the brain event-related potentials in children with Asperger syndromeT Lepistö
Cognitive Brain Research Unit, Department of Psychology, P O Box 9, FIN 00014 University of Helsinki, Finland
Clin Neurophysiol 117:2161-71. 2006..We investigated auditory-discrimination and orienting in children with AS using an event-related potential (ERP) paradigm that was previously applied to children with autism...
Are different kinds of acoustic features processed differently for speech and non-speech sounds?M Jaramillo
Cognitive Brain Research Unit, Department of Psychology, University of Helsinki, PO Box 13, FIN-00014, Helsinki, Finland
Brain Res Cogn Brain Res 12:459-66. 2001..This result might reflect enhanced processing of duration features in the Finnish language in which phoneme duration plays a critical role...
Similarities in the phenotype of the auditory neural substrate in children with Asperger syndrome and their parentsE Jansson-Verkasalo
Cognitive Brain Research Unit, Department of Psychology, PO Box 9, 00014 University of Helsinki, Helsinki, Finland
Eur J Neurosci 22:986-90. 2005..The present results suggest that complex genetic mechanisms may contribute to auditory abnormalities encountered in children with AS...
Pre-attentive discriminability of sound order as a function of tone duration and interstimulus interval: a mismatch negativity studyM Tervaniemi
Cognitive Brain Research Unit, Department of Psychology, University of Helsinki, Finland
Audiol Neurootol 4:303-10. 1999....
Background acoustic noise and the hemispheric lateralization of speech processing in the human brain: magnetic mismatch negativity studyY Shtyrov
Department of Psychology, University of Helsinki, Finland
Neurosci Lett 251:141-4. 1998..However, in noisy conditions the involvement of the left hemisphere's auditory cortex in speech discrimination is considerably decreased, while that of the right hemisphere increases...
The processing of speech and non-speech sounds in aphasic patients as reflected by the mismatch negativity (MMN)Titta Ilvonen
Cognitive Brain Research Unit, Department of Psychology, University of Helsinki, Finland
Neurosci Lett 366:235-40. 2004..These results suggest that left-hemisphere lesions have differential effects on the discrimination of speech and acoustic features indicating that they have separate neural substrates...
Change and novelty detection in speech and non-speech sound streamsAlexander Sorokin
Cognitive Brain Research Unit, Institute of Behavioural Sciences, University of Helsinki, Helsinki, Finland
Brain Res 1327:77-90. 2010..The current MMN results imply enhanced processing of linguistically relevant information at the pre-attentive stage and in this way support the domain-specific model of speech perception...
Language impairment is reflected in auditory evoked fieldsElina Pihko
BioMag Laboratory, Hospital District of Helsinki and Uusimaa HUSLAB, Helsinki University Central Hospital, Helsinki, Finland
Int J Psychophysiol 68:161-9. 2008..The results indicate that the SLI group, having weaker responses to the onsets of sounds, might have slightly depressed sensory encoding...
Disruption of immediate memory and brain processes: an auditory ERP protocolTom Campbell
Helsinki Collegium for Advanced Studies, University of Helsinki, Finland
Brain Res Brain Res Protoc 14:77-86. 2005..Using this approach, it has been shown that the neural processes involved in the elicitation of the auditory N1 ERP response may be involved in the disruption of memory for serial order produced by irrelevant sound...
Effects of naltrexone and ethanol on auditory event-related brain potentialsI P Jääskeläinen
Department of Psychology, University of Helsinki, Finland
Alcohol 15:105-11. 1998..Furthermore, the N2b amplitude was significantly suppressed in the interaction condition, suggesting attentional impairment...
Enhanced brain activity preceding voluntary movement in early blind humansA Lehtokoski
Department of Psychology, University of Helsinki, Finland
Neurosci Lett 253:155-8. 1998..The results suggest functional changes in the blind subjects' brain activity, presumably, in the cortical areas involved in preparation and initiation of voluntary movement...
No effects of mobile phone use on cortical auditory change-detection in children: an ERP studyMyoung Soo Kwon
Department of Psychology, Centre for Cognitive Neuroscience, University of Turku, Assistentinkatu 7, Turku, Finland
Bioelectromagnetics 31:191-9. 2010..However, it should be noted that the present study only had sufficient statistical power to detect a large effect size...
Long-term exposure to noise impairs cortical sound processing and attention controlTeija Kujala
Helsinki Collegium for Advanced Studies, University of Helsinki, Finland
Psychophysiology 41:875-81. 2004..These results demonstrate that long-term exposure to noise has long-lasting detrimental effects on central auditory processing and attention control...
The effect of different noise types on the speech and non-speech elicited mismatch negativityH Kozou
Department of Psychology, Cognitive Brain Research Unit, University of Helsinki, P.O. Box 9, FIN-00014 Helsinki, Finland
Hear Res 199:31-9. 2005..Babble and industrial noises dramatically reduced the MMN amplitudes for both stimulus types, while traffic noise affected only speech stimuli...
Mismatch negativity brain response as an index of speech perception recovery in cochlear-implant recipientsEila Lonka
Department of Phonetics, University of Helsinki, Helsinki, Finland
Audiol Neurootol 9:160-2. 2004..We found that speech discrimination improved over time and the MMN, observed in all patients after 2.5 years of CI use, was first seen for the larger vowel difference and later for the smaller one...
Auditory cortical change detection in adults with Asperger syndromeTuulia Lepistö
Cognitive Brain Research Unit, Department of Psychology, P O Box 9, University of Helsinki, and Department of Child Neurology, Helsinki University Central Hospital, Finland
Neurosci Lett 414:136-40. 2007..The results are consistent with those reported earlier in children with AS, except for the duration-MMN, which was diminished in children and enhanced in adults...
Fast multi-feature paradigm for recording several mismatch negativities (MMNs) to phonetic and acoustic changes in speech soundsSatu Pakarinen
Cognitive Brain Research Unit, University of Helsinki, Helsinki, Finland Helsinki Brain Research Centre, Helsinki, Finland
Biol Psychol 82:219-26. 2009..Thus, this new multi-feature paradigm with speech stimuli provides similar results as the oddball paradigm, and the MMNs recorded with the new paradigm were reproducible...
Language abilities of children with Asperger syndromeSatu Saalasti
Cognitive Brain Research Unit, Department of Psychology, University of Helsinki, Helsinki, Finland
J Autism Dev Disord 38:1574-80. 2008..The results suggest that receptive language processes should be studied in detail in children with AS...
Word semantics is processed even without attentional effortKristiina Relander
Department of Psychology, University of Helsinki, Finland
J Cogn Neurosci 21:1511-22. 2009....
Distinct gamma-band evoked responses to speech and non-speech sounds in humansSatu Palva
Cognitive Brain Research Unit, Department of Psychology, FIN 00014 University of Helsinki, Finland
J Neurosci 22:RC211. 2002..Consequently, speech-specific neuronal processing may commence no later than 40-60 msec from stimulus onset, possibly in the form of activation of language-specific memory traces...
Auditory discrimination profiles of speech sound changes in 6-year-old children as determined with the multi-feature MMN paradigmRiikka Lovio
Department of Psychology, Cognitive Brain Research Unit, University of Helsinki, P O Box 9, Helsinki 00014, Finland
Clin Neurophysiol 120:916-21. 2009..Similar MMNs in the two paradigms would suggest that they tap the same processes. This would promote the usefulness of the more time-efficient multi-feature paradigm for future studies in children...
Auditory processing that leads to conscious perception: a unique window to central auditory processing opened by the mismatch negativity and related responsesRisto Naatanen
Department of Psychology, University of Tartu, Tartu, Estonia
Psychophysiology 48:4-22. 2011..Special attention is paid to determining the neural processes that might underlie conscious perception and the borderline between automatic and attention-dependent processes in audition...
Abnormal pattern of cortical speech feature discrimination in 6-year-old children at risk for dyslexiaRiikka Lovio
Cognitive Brain Research Unit, Faculty of Behavioural Sciences, University of Helsinki, Helsinki, Finland
Brain Res 1335:53-62. 2010..However, the current study, enabling the recording of MMN for multiple sound features, suggests the presence of wide-spread auditory difficulties in children at risk for dyslexia...
Long-term exposure to occupational noise alters the cortical organization of sound processingElvira Brattico
Cognitive Brain Research Unit, Department of Psychology, University of Helsinki, P O Box 9 Siltavuorenpenger 20 C, FIN 00014 Helsinki, Finland
Clin Neurophysiol 116:190-203. 2005..Long-term exposure to noise may cause an altered hemispheric lateralization of speech processing even in silent conditions. We examined whether this lateralization shift is speech specific or occurs also for other sounds...
Auditory discrimination after left-hemisphere stroke: a mismatch negativity follow-up studyTitta-Maria Ilvonen
Cognitive Brain Research Unit, Department of Psychology, University of Helsinki, Finland
Stroke 34:1746-51. 2003..CONCLUSIONS: These results suggest that the MMN can be used as an index of the recovery of auditory discrimination...
The discrimination of and orienting to speech and non-speech sounds in children with autismTuulia Lepistö
Cognitive Brain Research Unit, Department of Psychology, P O Box 9, University of Helsinki FIN 00014, Finland
Brain Res 1066:147-57. 2005..This has been proposed to be one of the earliest symptoms to emerge, with pervasive effects on later development...
N1 and the mismatch negativity are spatiotemporally distinct ERP components: disruption of immediate memory by auditory distraction can be related to N1Tom Campbell
Helsinki Collegium for Advanced Studies, University of Helsinki, Helsinki, Finland
Psychophysiology 44:530-40. 2007..Implications are discussed for the N1 hypothesis and the changing-state hypothesis of the disruption of serial recall performance by auditory distraction...
Semantic processing in comatose patients with intact temporal lobes as reflected by the N400 event-related potentialPia Rämä
Cognitive Brain Research Unit, Department of Psychology, University of Helsinki, Finland
Neurosci Lett 474:88-92. 2010..In contrast, patients with an injured temporal lobe showed no such effect...
Preattentive auditory information processing under exposure to the 902 MHz GSM mobile phone electromagnetic field: a mismatch negativity (MMN) studyMyoung Soo Kwon
Department of Psychology, Centre for Cognitive Neuroscience, University of Turku, Assistentinkatu 7, Turku, Finland
Bioelectromagnetics 30:241-8. 2009..In the present study, we found no conclusive evidence that acute exposure to GSM mobile phone EMF affects cortical auditory change detection processing reflected by the MMN...
Comparison of blind and sighted participants' performance in a letter recognition working memory taskIrina Bliss
Department of Psychology, Centre for Cognitive Neuroscience, University of Turku, Assistentinkatu 7, FIN 20014, Turku, Finland
Brain Res Cogn Brain Res 18:273-7. 2004..The performance level of blind persons relying on their tactile skills is just about the same as that of sighted subjects relying on their visual skills...
The N1 hypothesis and irrelevant sound: evidence from token set size effectsTom Campbell
Cognitive Brain Research Unit, University of Helsinki, Helsinki, Finland
Brain Res Cogn Brain Res 18:39-47. 2003..This result suggested that, if N1 were to play a role in the disruption produced by irrelevant sound, the processes underlying the N1 wave may only serve as a necessary rather than a sufficient condition for disruption...
Group intervention changes brain activity in bilingual language-impaired childrenElina Pihko
BioMag Laboratory, Helsinki University Central Hospital, Helsinki, Finland
Cereb Cortex 17:849-58. 2007..Our results show that, in children with SLI, the positive intervention effect is reflected in plastic changes in the brain activity of the left and right auditory cortices...
The mismatch negativity (MMN)--a unique window to disturbed central auditory processing in ageing and different clinical conditionsR Naatanen
Institute of Psychology, University of Tartu, Tartu, Estonia, Finland
Clin Neurophysiol 123:424-58. 2012..In fact, MMN deficiency appears to index cognitive decline irrespective of the specific symptomatologies and aetiologies of the different disorders involved...
Native and foreign vowel discrimination as indexed by the mismatch negativity (MMN) responseMaija S Peltola
Department of Phonetics, University of Turku, FIN 20014 Turku, Finland
Neurosci Lett 352:25-8. 2003..The results suggest that learning in classroom environment may not lead to the formation of new long-term native-like memory traces...
Effects of unilateral hippocampus-amygdala-partial temporal lobe resection on auditory EEG/MEG responses: a case studyHeikki Hamalainen
Department of Psychology and Centre for Cognitive Neuroscience, University of Turku, Turku, Finland
Scand J Psychol 48:367-73. 2007..These results give support to the notions about the role of the amygdala and hippocampus in alerting and orienting, respectively, and of the temporal cortex in auditory discrimination...
Automatic and controlled processing of acoustic and phonetic contrastsElyse Sussman
Department of Neuroscience and Department of Otolaryngology, Albert Einstein College of Medicine, 1410 Pelham Parkway S, Bronx, NY, USA
Hear Res 190:128-40. 2004..Differences occurred only in later stages associated with controlled processes. The effects of position and attention on speech and non-speech stimuli are discussed...
Language context and phonetic change detectionIstvan Winkler
Department of General Psychology, Institute for Psychology, Hungarian Academy of Sciences, PO Box 398, Szondi u 83 85, H 1394 Budapest, Hungary
Brain Res Cogn Brain Res 17:833-44. 2003..Language context had no effect on the mismatch negativity ERP component elicited by the deviant word stimuli. This result suggests that language context does not affect the pre-attentive detection of auditory deviance...
Magnetic fields evoked by speech sounds in preschool childrenElina Pihko
BioMag Laboratory, Helsinki University Central Hospital, P O Box 340, FIN 00029 HUS, Finland
Clin Neurophysiol 116:112-9. 2005....
Diagnostic subgroups of developmental dyslexia have different deficits in neural processing of tones and phonemesThomas Lachmann
Department of Psychology, University of Leipzig, Germany
Int J Psychophysiol 56:105-20. 2005....
The mismatch negativity and reaction time as indices of the perceptual distance between the corresponding vowels of two related languagesJanne Savela
Department of Phonetics Juslenia, University of Turku, FIN 20014, Turku, Finland
Brain Res Cogn Brain Res 16:250-6. 2003..No such pattern was found for the MMN. Thus, the phonemic status of the standard stimulus seems to play a role at the attentive but not at the pre-attentive level...
From symbols to sounds: visual symbolic information activates sound representationsAndreas Widmann
Institut für Allgemeine Psychologie, University of Leipzig, Germany
Psychophysiology 41:709-15. 2004..These results suggest that the auditory system can establish a representation of an expected stimulus on the basis of visual symbolic information...
Binding symbols and sounds: evidence from event-related oscillatory gamma-band activityAndreas Widmann
Institute of Psychology I, University of Leipzig, Seeburgstrasse 14 20, D 04103, Leipzig, Germany
Cereb Cortex 17:2696-702. 2007..Gamma-band responses were not present for unexpected incongruent sounds. A model explaining the anticipatory activation of cortical auditory representations and the match of experience against expectation is presented...
Perception of matching and conflicting audiovisual speech in dyslexic and fluent readers: an fMRI study at 3 TJohanna Pekkola
Laboratory of Computational Engineering, Helsinki University of Technology, Espoo, Finland
Neuroimage 29:797-807. 2006....
Word-specific cortical activity as revealed by the mismatch negativityFriedemann Pulvermüller
Medical Research Council, Cognition and Brain Sciences Unit, Cambridge, UK
Psychophysiology 41:106-12. 2004....
The auditory sensory memory trace decays rapidly in newbornsMarie Cheour
Language and the Developing Brain Laboratory, Center for Cognitive Neuroscience, University of Turku, Finland
Scand J Psychol 43:33-9. 2002..In view of the fact that in adults MMN is elicited even with a 10s SOA, these results imply that the time span of auditory memory is considerably shorter in neonates than in adults and 8-12-year-old children...
