Timo U Kosunen

Summary

Affiliation: University of Helsinki
Country: Finland

Publications

  1. ncbi request reprint Increase of allergen-specific immunoglobulin E antibodies from 1973 to 1994 in a Finnish population and a possible relationship to Helicobacter pylori infections
    T U Kosunen
    Department of Bacteriology and Immunology, Haartman Institute and Helsinki University Central Hospital, University of Helsinki, Helsinki, Finland
    Clin Exp Allergy 32:373-8. 2002
  2. doi request reprint Gastric cancers in Finnish patients after cure of Helicobacter pylori infection: A cohort study
    Timo U Kosunen
    Department of Bacteriology and Immunology, Haartman Institute, University of Helsinki, Helsinki, Finland
    Int J Cancer 128:433-9. 2011
  3. ncbi request reprint Association of Helicobacter pylori IgA antibodies with the risk of peptic ulcer disease and gastric cancer
    Timo U Kosunen
    Department of Bacteriology and Immunology, University of Helsinki, PO Box 21, FIN 00014 Helsinki, Finland
    World J Gastroenterol 11:6871-4. 2005
  4. ncbi request reprint Helicobacter pylori IgA and IgG antibodies, serum pepsinogen I and the risk of gastric cancer: changes in the risk with extended follow-up period
    Paul Knekt
    National Public Health Institute, Helsinki, Finland
    Int J Cancer 119:702-5. 2006
  5. ncbi request reprint Clinical significance of widespread gastric metaplasia in the duodenal bulb
    Lea Veijola
    Department of Bacteriology and Immunology, Haartman Institute, University of Helsinki, Finland
    J Clin Gastroenterol 40:510-4. 2006
  6. ncbi request reprint Infectious burden as a determinant of atopy-- a comparison between adults in Finnish and Russian Karelia
    Leena C von Hertzen
    Skin and Allergy Hospital, Helsinki University Central Hospital, Helsinki, Finland
    Int Arch Allergy Immunol 140:89-95. 2006
  7. ncbi request reprint Helicobacter pylori infection in Finland
    Hilpi Rautelin
    Department of Bacteriology and Immunology, Haartman Institute, University of Helsinki, Helsinki University Central Hospital Laboratory Diagnostics, Helsinki, Finland
    Ann Med 36:82-8. 2004
  8. doi request reprint A "screen-and-treat" approach for Helicobacter pylori infection: a population-based study in Vammala, Finland
    Anniina Salomaa-Rasanen
    Department of Bacteriology and Immunology, Haartman Institute, University of Helsinki, Helsinki, Finland
    Helicobacter 15:28-37. 2010
  9. ncbi request reprint Accelerated decline in Helicobacter pylori seroprevalence rate during the screen and treat project in Vammala, Finland, as demonstrated in 29- to 45-year-old pregnant women
    Leena Rehnberg-Laiho
    Department of Bacteriology and Immunology, Haartman Institute, Haartmaninkatu 3, 00014 University of Helsinki, Helsinki, Finland
    APMIS 112:34-8. 2004
  10. ncbi request reprint Spontaneous disappearance of Helicobacter pylori antibodies in patients with advanced atrophic corpus gastritis
    Arto Kokkola
    Department of Surgery, Helsinki University Central Hospital, Helsinki, Finland
    APMIS 111:619-24. 2003

Collaborators

Detail Information

Publications18

  1. ncbi request reprint Increase of allergen-specific immunoglobulin E antibodies from 1973 to 1994 in a Finnish population and a possible relationship to Helicobacter pylori infections
    T U Kosunen
    Department of Bacteriology and Immunology, Haartman Institute and Helsinki University Central Hospital, University of Helsinki, Helsinki, Finland
    Clin Exp Allergy 32:373-8. 2002
    ..The increase may be associated with decreased rates of infections such as measles, hepatitis A, tuberculosis, toxoplasmosis, and, as recently suggested, Helicobacter pylori gastritis...
  2. doi request reprint Gastric cancers in Finnish patients after cure of Helicobacter pylori infection: A cohort study
    Timo U Kosunen
    Department of Bacteriology and Immunology, Haartman Institute, University of Helsinki, Helsinki, Finland
    Int J Cancer 128:433-9. 2011
    ..To conclude, cured H. pylori infection led to a significantly decreased incidence of gastric cancers from the sixth follow-up year. Advanced atrophic gastritis would be a plausible contributor to the elevated SIR in elderly Hp- patients...
  3. ncbi request reprint Association of Helicobacter pylori IgA antibodies with the risk of peptic ulcer disease and gastric cancer
    Timo U Kosunen
    Department of Bacteriology and Immunology, University of Helsinki, PO Box 21, FIN 00014 Helsinki, Finland
    World J Gastroenterol 11:6871-4. 2005
    ..To compare the prevalence of Helicobacter pylori (H pylori) IgG and IgA antibodies between adult subjects, with defined gastric diseases, non-defined gastric disorders and those representing the population...
  4. ncbi request reprint Helicobacter pylori IgA and IgG antibodies, serum pepsinogen I and the risk of gastric cancer: changes in the risk with extended follow-up period
    Paul Knekt
    National Public Health Institute, Helsinki, Finland
    Int J Cancer 119:702-5. 2006
    ....
  5. ncbi request reprint Clinical significance of widespread gastric metaplasia in the duodenal bulb
    Lea Veijola
    Department of Bacteriology and Immunology, Haartman Institute, University of Helsinki, Finland
    J Clin Gastroenterol 40:510-4. 2006
    ..All the risk factors of peptic ulcer disease are not thoroughly understood...
  6. ncbi request reprint Infectious burden as a determinant of atopy-- a comparison between adults in Finnish and Russian Karelia
    Leena C von Hertzen
    Skin and Allergy Hospital, Helsinki University Central Hospital, Helsinki, Finland
    Int Arch Allergy Immunol 140:89-95. 2006
    ..We investigated the association between markers of infections and occurrence of atopy among adults in eastern Finland and western Russia, two adjacent areas with profound differences in living conditions and lifestyles...
  7. ncbi request reprint Helicobacter pylori infection in Finland
    Hilpi Rautelin
    Department of Bacteriology and Immunology, Haartman Institute, University of Helsinki, Helsinki University Central Hospital Laboratory Diagnostics, Helsinki, Finland
    Ann Med 36:82-8. 2004
    ..In this survey, young inhabitants were offered diagnosis and treatment for H. pylori...
  8. doi request reprint A "screen-and-treat" approach for Helicobacter pylori infection: a population-based study in Vammala, Finland
    Anniina Salomaa-Rasanen
    Department of Bacteriology and Immunology, Haartman Institute, University of Helsinki, Helsinki, Finland
    Helicobacter 15:28-37. 2010
    ..pylori"screen-treat-retest-and-retreat" program for all young adults at primary health care in Vammala, Finland after a pilot study in 1994 including 504 subjects aged 15-75...
  9. ncbi request reprint Accelerated decline in Helicobacter pylori seroprevalence rate during the screen and treat project in Vammala, Finland, as demonstrated in 29- to 45-year-old pregnant women
    Leena Rehnberg-Laiho
    Department of Bacteriology and Immunology, Haartman Institute, Haartmaninkatu 3, 00014 University of Helsinki, Helsinki, Finland
    APMIS 112:34-8. 2004
    ..6% versus 13.5%, respectively, p=0.0433, chi-square test). The final outcome of the intervention project, i.e. the long-term effect of this decline on gastric cancer and peptic ulcer disease, remains to be evaluated...
  10. ncbi request reprint Spontaneous disappearance of Helicobacter pylori antibodies in patients with advanced atrophic corpus gastritis
    Arto Kokkola
    Department of Surgery, Helsinki University Central Hospital, Helsinki, Finland
    APMIS 111:619-24. 2003
    ..The disappearance of H. pylori antibodies is accompanied by no or more than a mild improvement of the gastric mucosa...
  11. ncbi request reprint Eradication of Helicobacter pylori improves the healing rate and reduces the relapse rate of nonbleeding ulcers in patients with bleeding peptic ulcer
    Perttu E T Arkkila
    Department of Medicine, Division of Gastroenterology, Helsinki University Central Hospital, Helsinki, Finland
    Am J Gastroenterol 98:2149-56. 2003
    ..pylori) and peptic ulcer complications remains obscure. The aim of this study was to determine the importance of H. pylori and other risk factors for healing rate, ulcer recurrence, and rebleeding in patients with bleeding peptic ulcer...
  12. pmc Environmental biodiversity, human microbiota, and allergy are interrelated
    Ilkka Hanski
    Department of Biosciences, University of Helsinki, FI 00014 Helsinki, Finland
    Proc Natl Acad Sci U S A 109:8334-9. 2012
    ..These results raise fundamental questions about the consequences of biodiversity loss for both allergic conditions and public health in general...
  13. ncbi request reprint Growing disparities in atopy between the Finns and the Russians: a comparison of 2 generations
    Leena von Hertzen
    Skin and Allergy Hospital, Helsinki University Central Hospital, Helsinki, Finland
    J Allergy Clin Immunol 117:151-7. 2006
    ..We examined the occurrence and risk factors of atopy among schoolchildren and their mothers in 2 geographically adjacent areas with fundamental differences in living conditions and lifestyles...
  14. ncbi request reprint Helicobacter pylori-induced indoleamine 2,3-dioxygenase activity in vivo is regulated by TGFB1 and CTLA4 polymorphisms
    Annika Raitala
    University of Tampere Medical School, Tampere, Finland
    Mol Immunol 44:1011-4. 2007
    ..This suggests that H. pylori induced IDO activity is regulated by TGFB1 and CTLA4, and that IDO is a mediator of the T cell suppressive effects of these genes...
  15. doi request reprint Cure of Helicobacter pylori infection in all compliant patients: report on 644 subjects
    Kari Seppala
    Scand J Gastroenterol 43:1149-50. 2008
  16. ncbi request reprint Helicobacter pylori eradication as the sole treatment for gastric and duodenal ulcers
    Perttu Et Arkkila
    Department of Medicine, Division of Gastroenterology, Helsinki University Central Hospital, Finland
    Eur J Gastroenterol Hepatol 17:93-101. 2005
    ..We also looked at the impact of non-steroidal anti-inflammatory drug (NSAID) and acetylsalicylic acid (ASA) use on ulcer relapses...
  17. ncbi request reprint Prevention and suppression of Helicobacter felis infection in mice using colostral preparation with specific antibodies
    Pertti Marnila
    MTT, Agrifood Research Finland, Food Research, Jokioinen, Finland
    Helicobacter 8:192-201. 2003
    ..Efficacies of colostral control preparation and immune preparation containing specific antibodies against Helicobacter felis were studied in the prevention and treatment of experimental H. felis infection in mice...
  18. ncbi request reprint Indoleamine 2,3-dioxygenase (IDO) activity is lower in atopic than in non-atopic individuals and is enhanced by environmental factors protecting from atopy
    Annika Raitala
    University of Tampere Medical School, Tampere, Finland
    Mol Immunol 43:1054-6. 2006
    ..As expected, IDO activity was significantly higher in their presence than absence...