Juha W Koskenvuo

Summary

Affiliation: University of Turku
Country: Finland

Publications

  1. pmc Cardiac Function, Perfusion, Metabolism, and Innervation following Autologous Stem Cell Therapy for Acute ST-Elevation Myocardial Infarction. A FINCELL-INSIGHT Sub-Study with PET and MRI
    Maija T Mäki
    Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital Turku, Finland
    Front Physiol 3:6. 2012
  2. pmc Intracardiac injection of a capsid-modified Ad5/35 results in decreased heart toxicity when compared to standard Ad5
    Raine Toivonen
    Turku Centre for Biotechnology, University of Turku, Tykistökatu 6B 5th floor, Turku, FIN 20520, Finland
    Virol J 9:296. 2012
  3. doi request reprint Fractionation of mouse bone-marrow cells limits functional efficacy in non-reperfused mouse model of acute myocardial infarction
    Juha W Koskenvuo
    Division of Cardiology, Department of Medicine, University of California, San Francisco, San Francisco, CA, USA
    Ann Med 44:829-35. 2012
  4. doi request reprint Evidence of diminished coronary flow in pulmonary hypertension: explaining angina pectoris in this patient group?
    Juha W Koskenvuo
    Division of Cardiology, Department of Medicine, University of California, San Francisco, USA
    Clin Physiol Funct Imaging 31:477-84. 2011
  5. ncbi request reprint Cardiopulmonary involvement in Fabry's disease
    Juha W Koskenvuo
    Dept of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Finland
    Acta Cardiol 65:185-92. 2010
  6. pmc A comparison of echocardiography to invasive measurement in the evaluation of pulmonary arterial hypertension in a rat model
    Juha W Koskenvuo
    Division of Cardiology, Department of Medicine, University of California, 505 Parnassus Avenue, Box 0103, San Francisco, CA 94143, USA
    Int J Cardiovasc Imaging 26:509-18. 2010
  7. doi request reprint Echocardiography in Fabry disease: diagnostic value of endocardial border binary appearance
    Juha W Koskenvuo
    Department of Clinical Physiology, Nuclear Medicine and PET Centre, Turku University Hospital, Turku, Finland
    Clin Physiol Funct Imaging 29:177-80. 2009
  8. doi request reprint Cardiac magnetic resonance imaging in valvular heart disease
    Juha W Koskenvuo
    Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland
    Clin Physiol Funct Imaging 29:229-40. 2009
  9. doi request reprint Twenty-four-month alpha-galactosidase A replacement therapy in Fabry disease has only minimal effects on symptoms and cardiovascular parameters
    J W Koskenvuo
    Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Kiinamyllynkatu 4 8, FIN 20520, Turku, Finland
    J Inherit Metab Dis 31:432-41. 2008
  10. ncbi request reprint Cardiac MRI: accuracy of simultaneous measurement of left and right ventricular parameters using three different sequences
    Juha W Koskenvuo
    Department of Clinical Physiology, Nuclear Medicine and PET, Turku University Hospital, Turku, Finland
    Clin Physiol Funct Imaging 27:385-93. 2007

Collaborators

Detail Information

Publications28

  1. pmc Cardiac Function, Perfusion, Metabolism, and Innervation following Autologous Stem Cell Therapy for Acute ST-Elevation Myocardial Infarction. A FINCELL-INSIGHT Sub-Study with PET and MRI
    Maija T Mäki
    Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital Turku, Finland
    Front Physiol 3:6. 2012
    ..However, no consistently better outcome was observed in the BMC-treated group compared to placebo...
  2. pmc Intracardiac injection of a capsid-modified Ad5/35 results in decreased heart toxicity when compared to standard Ad5
    Raine Toivonen
    Turku Centre for Biotechnology, University of Turku, Tykistökatu 6B 5th floor, Turku, FIN 20520, Finland
    Virol J 9:296. 2012
    ....
  3. doi request reprint Fractionation of mouse bone-marrow cells limits functional efficacy in non-reperfused mouse model of acute myocardial infarction
    Juha W Koskenvuo
    Division of Cardiology, Department of Medicine, University of California, San Francisco, San Francisco, CA, USA
    Ann Med 44:829-35. 2012
    ....
  4. doi request reprint Evidence of diminished coronary flow in pulmonary hypertension: explaining angina pectoris in this patient group?
    Juha W Koskenvuo
    Division of Cardiology, Department of Medicine, University of California, San Francisco, USA
    Clin Physiol Funct Imaging 31:477-84. 2011
    ..The role of pulmonary artery dilatation, septal wall motion abnormality, cardiac output or diastolic blood pressure in determining coronary blood flow (CBF) during PH was determined...
  5. ncbi request reprint Cardiopulmonary involvement in Fabry's disease
    Juha W Koskenvuo
    Dept of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Finland
    Acta Cardiol 65:185-92. 2010
    ..Decreased enzyme activity leads to accumulation of glycosphingolipid in different tissues, including endothelial and smooth-muscle cells and cardiomyocytes...
  6. pmc A comparison of echocardiography to invasive measurement in the evaluation of pulmonary arterial hypertension in a rat model
    Juha W Koskenvuo
    Division of Cardiology, Department of Medicine, University of California, 505 Parnassus Avenue, Box 0103, San Francisco, CA 94143, USA
    Int J Cardiovasc Imaging 26:509-18. 2010
    ..These non-invasive parameters may be used to replace invasive measurements in detecting successful disease induction and to complement invasive data in the evaluation of PAH severity in a rat model...
  7. doi request reprint Echocardiography in Fabry disease: diagnostic value of endocardial border binary appearance
    Juha W Koskenvuo
    Department of Clinical Physiology, Nuclear Medicine and PET Centre, Turku University Hospital, Turku, Finland
    Clin Physiol Funct Imaging 29:177-80. 2009
    ..It has been suggested that this sign could be used with good accuracy to differentiate Fabry disease from hypertrophic cardiomyopathy and even as a first filter to screen for suspected Fabry disease...
  8. doi request reprint Cardiac magnetic resonance imaging in valvular heart disease
    Juha W Koskenvuo
    Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland
    Clin Physiol Funct Imaging 29:229-40. 2009
    ..We also discuss clinical applications of CMR in VHD. Furthermore, we describe how a CMR study statement should be structured in order to increase clinical use of this valuable methodology in cardiology...
  9. doi request reprint Twenty-four-month alpha-galactosidase A replacement therapy in Fabry disease has only minimal effects on symptoms and cardiovascular parameters
    J W Koskenvuo
    Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Kiinamyllynkatu 4 8, FIN 20520, Turku, Finland
    J Inherit Metab Dis 31:432-41. 2008
    ..Furthermore, longer follow-up studies are needed to assess the effects of ERT on prognosis...
  10. ncbi request reprint Cardiac MRI: accuracy of simultaneous measurement of left and right ventricular parameters using three different sequences
    Juha W Koskenvuo
    Department of Clinical Physiology, Nuclear Medicine and PET, Turku University Hospital, Turku, Finland
    Clin Physiol Funct Imaging 27:385-93. 2007
    ..Furthermore, we studied whether shortened acquisition time has an effect on the accuracy of left and right ventricular parameters both in healthy volunteers and in patients with cardiovascular disease...
  11. ncbi request reprint Correlation of transthoracic Doppler echocardiography and magnetic resonance imaging in measuring left anterior descending artery flow velocity and time-course of dipyridamole-induced coronary flow increase
    J W Koskenvuo
    Department of Clinical Physiology, Turku University Hospital, Turku, Finland
    Scand J Clin Lab Invest 63:65-72. 2003
    ....
  12. ncbi request reprint Ingested acidic food and liquids may lead to misinterpretation of 24-hour ambulatory pH tests: focus on measurement of extra-esophageal reflux
    Juha W Koskenvuo
    Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Kiinamyllynkatu 4 8, FIN 20520, Turku, Finland
    Dig Dis Sci 52:1678-84. 2007
    ..We recommend avoiding acidic food intake during esophageal pH testing...
  13. pmc Effects of cognac on coronary flow reserve and plasma antioxidant status in healthy young men
    Tuomas O Kiviniemi
    Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland
    Cardiovasc Ultrasound 6:25. 2008
    ..The purpose of this randomized controlled cross-over study was to determine whether moderate doses of cognac improve coronary reactivity as assessed with cold pressor testing (CPT) and coronary flow reserve (CFR) measurement...
  14. doi request reprint High dose of red wine elicits enhanced inhibition of fibrinolysis
    Tuomas O Kiviniemi
    Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland
    Eur J Cardiovasc Prev Rehabil 16:161-3. 2009
    ..The purpose of this randomized controlled cross-over study was to determine the acute effects of high doses of alcoholic beverages on circulating markers related to atherosclerosis and fibrinolysis...
  15. doi request reprint Decreased endothelin-1 levels after acute consumption of red wine and de-alcoholized red wine
    Tuomas O Kiviniemi
    Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland
    Atherosclerosis 211:283-6. 2010
    ..The purpose of this randomized trial was to determine the acute effects of these beverages on endothelin-1 levels and compare them to coronary artery epicardial diameter and flow rate...
  16. pmc Coronary artery flow velocity profile measured by transthoracic Doppler echocardiography predicts myocardial viability after acute myocardial infarction
    Antti Saraste
    Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Kiinamyllynkatu 6 8, 20520 Turku, Finland
    Heart 93:456-7. 2007
    ....
  17. ncbi request reprint Vasodilation of epicardial coronary artery can be measured with transthoracic echocardiography
    Tuomas O Kiviniemi
    Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland
    Ultrasound Med Biol 33:362-70. 2007
    ..6 to 8.2%), suggesting good reproducibility. This study demonstrates that TTE can be used to assess changes in both epicardial coronary artery diameter and flow velocity simultaneously in the distal LAD artery...
  18. ncbi request reprint A moderate dose of red wine, but not de-alcoholized red wine increases coronary flow reserve
    Tuomas O Kiviniemi
    Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Kiinamyllynkatu 4 8, FIN 20520 Turku, Finland
    Atherosclerosis 195:e176-81. 2007
    ..The purpose of this randomized controlled cross-over study was to determine whether moderate doses of red wine and de-alcoholized red wine improve coronary flow velocity reserve (CFR)...
  19. ncbi request reprint Comparison of MRI and positron emission tomography for measuring myocardial perfusion reserve in healthy humans
    Jussi P Pärkkä
    Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland
    Magn Reson Med 55:772-9. 2006
    ..04) between MRI and PET. However, we noticed that MRI provided lower MPR values compared to PET (2.5 +/- 1.0 vs. 4.3 +/- 1.8). We conclude that MRI supplemented with tracer kinetic modeling can be used to quantify myocardial perfusion...
  20. ncbi request reprint Coronary artery diameter can be assessed reliably with transthoracic echocardiography
    Tuomas O Kiviniemi
    Department of Clinical Physiology, Nuclear Medicine and PET, Turku University Hospital, FIN 20520 Turku, Finland
    Am J Physiol Heart Circ Physiol 286:H1515-20. 2004
    ..Interobserver variability of TTE measurements was low (coefficient of variation 5.4 +/- 4.6-7.5 +/- 8.8%). TTE is an accurate method to evaluate coronary artery diameter in patients with healthy coronary arteries...
  21. doi request reprint Timing of bone marrow cell therapy is more important than repeated injections after myocardial infarction
    Yan Zhang
    Division of Cardiology, Department of Medicine, University of California San Francisco, CA 94143 0103, USA
    Cardiovasc Pathol 20:204-12. 2011
    ..Bone marrow cell treatment has been proposed as a therapy for myocardial infarction, but the optimal timing and number of injections remain unknown...
  22. doi request reprint Treatment of pulmonary arterial hypertension with circulating angiogenic cells
    Rachel Mirsky
    Department of Medicine, University of California, San Francisco, San Francisco, California 94143, USA
    Am J Physiol Lung Cell Mol Physiol 301:L12-9. 2011
    ..Future studies should be geared toward either earlier therapeutic time points with varying doses of unmodified CACs or genetically modified cells as a means of delivery of factors to the pulmonary arterial circulation...
  23. ncbi request reprint Transthoracic Doppler echocardiography as a noninvasive tool to assess coronary artery stenoses--a comparison with quantitative coronary angiography
    Markku Saraste
    Department of Clinical Physiology, Turku University Hospital, Turku, Finland
    J Am Soc Echocardiogr 18:679-85. 2005
    ..Transthoracic echocardiography is a promising noninvasive technique to diagnose significant coronary artery stenoses...
  24. ncbi request reprint Determinants of coronary flow velocity reserve in healthy young men
    Tuomas O Kiviniemi
    Department of Clinical Physiology, Nuclear Medicine and PET, Turku University Hospital, Turku, Finland
    Am J Physiol Heart Circ Physiol 291:H564-9. 2006
    ..We found no relationship between CFVR and serum lipids or body mass index. We conclude that abdominal fat accumulation and low aerobic fitness are independently associated with CFVR in men...
  25. doi request reprint Diagnostic performance of cardiac magnetic resonance imaging in coronary artery disease
    Jussi P Pärkkä
    Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland
    Clin Physiol Funct Imaging 30:89-97. 2010
    ....
  26. pmc Intracoronary Levosimendan during Ischemia Prevents Myocardial Apoptosis
    Markus Malmberg
    Department of Surgery, Turku University Hospital Turku, Finland
    Front Physiol 3:17. 2012
    ..The effect on cardiac contractility was only significant in our perfusion heart model when levosimendan was delivered intravenously before ischemia...
  27. pmc Pravastatin-induced improvement in coronary reactivity and circulating ATP and ADP levels in young adults with type 1 diabetes
    Tuomas O Kiviniemi
    Department of Clinical Physiology, Turku University Hospital Turku, Finland
    Front Physiol 3:338. 2012
    ..This study provides a novel insight in purinergic mechanisms involved in pleiotropic effects of pravastatin...
  28. doi request reprint Cardiomyocyte apoptosis after antegrade and retrograde cardioplegia during aortic valve surgery
    Tommi Vähäsilta
    Department of Surgery, Turku University Hospital, University of Turku, Turku, Finland
    Ann Thorac Surg 92:1351-7. 2011
    ..We compared antegrade and retrograde cardioplegia in a randomized clinical trial to see whether it has effect on cardiomyocyte apoptosis and left ventricular function...