Research Topics
| Juha W KoskenvuoSummaryAffiliation: University of Turku Country: Finland Publications
| Collaborators
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Detail Information
Publications
Fractionation of mouse bone-marrow cells limits functional efficacy in non-reperfused mouse model of acute myocardial infarctionJuha W Koskenvuo
Division of Cardiology, Department of Medicine, University of California, San Francisco, San Francisco, CA, USA
Ann Med 44:829-35. 2012....
Correlation of transthoracic Doppler echocardiography and magnetic resonance imaging in measuring left anterior descending artery flow velocity and time-course of dipyridamole-induced coronary flow increaseJ W Koskenvuo
Department of Clinical Physiology, Turku University Hospital, Turku, Finland
Scand J Clin Lab Invest 63:65-72. 2003....
Evidence of diminished coronary flow in pulmonary hypertension: explaining angina pectoris in this patient group?Juha W Koskenvuo
Division of Cardiology, Department of Medicine, University of California, San Francisco, USA
Clin Physiol Funct Imaging 31:477-84. 2011..The role of pulmonary artery dilatation, septal wall motion abnormality, cardiac output or diastolic blood pressure in determining coronary blood flow (CBF) during PH was determined...
Cardiopulmonary involvement in Fabry's diseaseJuha W Koskenvuo
Dept of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Finland
Acta Cardiol 65:185-92. 2010..Decreased enzyme activity leads to accumulation of glycosphingolipid in different tissues, including endothelial and smooth-muscle cells and cardiomyocytes...
A comparison of echocardiography to invasive measurement in the evaluation of pulmonary arterial hypertension in a rat modelJuha W Koskenvuo
Division of Cardiology, Department of Medicine, University of California, 505 Parnassus Avenue, Box 0103, San Francisco, CA 94143, USA
Int J Cardiovasc Imaging 26:509-18. 2010..These non-invasive parameters may be used to replace invasive measurements in detecting successful disease induction and to complement invasive data in the evaluation of PAH severity in a rat model...
Echocardiography in Fabry disease: diagnostic value of endocardial border binary appearanceJuha W Koskenvuo
Department of Clinical Physiology, Nuclear Medicine and PET Centre, Turku University Hospital, Turku, Finland
Clin Physiol Funct Imaging 29:177-80. 2009..It has been suggested that this sign could be used with good accuracy to differentiate Fabry disease from hypertrophic cardiomyopathy and even as a first filter to screen for suspected Fabry disease...
Cardiac magnetic resonance imaging in valvular heart diseaseJuha W Koskenvuo
Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland
Clin Physiol Funct Imaging 29:229-40. 2009..We also discuss clinical applications of CMR in VHD. Furthermore, we describe how a CMR study statement should be structured in order to increase clinical use of this valuable methodology in cardiology...
Twenty-four-month alpha-galactosidase A replacement therapy in Fabry disease has only minimal effects on symptoms and cardiovascular parametersJ W Koskenvuo
Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Kiinamyllynkatu 4 8, FIN 20520, Turku, Finland
J Inherit Metab Dis 31:432-41. 2008..Furthermore, longer follow-up studies are needed to assess the effects of ERT on prognosis...
Cardiac MRI: accuracy of simultaneous measurement of left and right ventricular parameters using three different sequencesJuha W Koskenvuo
Department of Clinical Physiology, Nuclear Medicine and PET, Turku University Hospital, Turku, Finland
Clin Physiol Funct Imaging 27:385-93. 2007..Furthermore, we studied whether shortened acquisition time has an effect on the accuracy of left and right ventricular parameters both in healthy volunteers and in patients with cardiovascular disease...
Ingested acidic food and liquids may lead to misinterpretation of 24-hour ambulatory pH tests: focus on measurement of extra-esophageal refluxJuha W Koskenvuo
Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Kiinamyllynkatu 4 8, FIN 20520, Turku, Finland
Dig Dis Sci 52:1678-84. 2007..We recommend avoiding acidic food intake during esophageal pH testing...
Effects of cognac on coronary flow reserve and plasma antioxidant status in healthy young menTuomas O Kiviniemi
Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland
Cardiovasc Ultrasound 6:25. 2008..The purpose of this randomized controlled cross-over study was to determine whether moderate doses of cognac improve coronary reactivity as assessed with cold pressor testing (CPT) and coronary flow reserve (CFR) measurement...
High dose of red wine elicits enhanced inhibition of fibrinolysisTuomas O Kiviniemi
Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland
Eur J Cardiovasc Prev Rehabil 16:161-3. 2009..The purpose of this randomized controlled cross-over study was to determine the acute effects of high doses of alcoholic beverages on circulating markers related to atherosclerosis and fibrinolysis...
Decreased endothelin-1 levels after acute consumption of red wine and de-alcoholized red wineTuomas O Kiviniemi
Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland
Atherosclerosis 211:283-6. 2010..The purpose of this randomized trial was to determine the acute effects of these beverages on endothelin-1 levels and compare them to coronary artery epicardial diameter and flow rate...
Vasodilation of epicardial coronary artery can be measured with transthoracic echocardiographyTuomas O Kiviniemi
Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland
Ultrasound Med Biol 33:362-70. 2007..6 to 8.2%), suggesting good reproducibility. This study demonstrates that TTE can be used to assess changes in both epicardial coronary artery diameter and flow velocity simultaneously in the distal LAD artery...
A moderate dose of red wine, but not de-alcoholized red wine increases coronary flow reserveTuomas O Kiviniemi
Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Kiinamyllynkatu 4 8, FIN 20520 Turku, Finland
Atherosclerosis 195:e176-81. 2007..The purpose of this randomized controlled cross-over study was to determine whether moderate doses of red wine and de-alcoholized red wine improve coronary flow velocity reserve (CFR)...
Comparison of MRI and positron emission tomography for measuring myocardial perfusion reserve in healthy humansJussi P Pärkkä
Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland
Magn Reson Med 55:772-9. 2006..04) between MRI and PET. However, we noticed that MRI provided lower MPR values compared to PET (2.5 +/- 1.0 vs. 4.3 +/- 1.8). We conclude that MRI supplemented with tracer kinetic modeling can be used to quantify myocardial perfusion...
Coronary artery flow velocity profile measured by transthoracic Doppler echocardiography predicts myocardial viability after acute myocardial infarctionAntti Saraste
Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Kiinamyllynkatu 6 8, 20520 Turku, Finland
Heart 93:456-7. 2007....
Coronary artery diameter can be assessed reliably with transthoracic echocardiographyTuomas O Kiviniemi
Department of Clinical Physiology, Nuclear Medicine and PET, Turku University Hospital, FIN 20520 Turku, Finland
Am J Physiol Heart Circ Physiol 286:H1515-20. 2004..Interobserver variability of TTE measurements was low (coefficient of variation 5.4 +/- 4.6-7.5 +/- 8.8%). TTE is an accurate method to evaluate coronary artery diameter in patients with healthy coronary arteries...
Transthoracic Doppler echocardiography as a noninvasive tool to assess coronary artery stenoses--a comparison with quantitative coronary angiographyMarkku Saraste
Department of Clinical Physiology, Turku University Hospital, Turku, Finland
J Am Soc Echocardiogr 18:679-85. 2005..Transthoracic echocardiography is a promising noninvasive technique to diagnose significant coronary artery stenoses...
Timing of bone marrow cell therapy is more important than repeated injections after myocardial infarctionYan Zhang
Division of Cardiology, Department of Medicine, University of California San Francisco, CA 94143 0103, USA
Cardiovasc Pathol 20:204-12. 2011..Bone marrow cell treatment has been proposed as a therapy for myocardial infarction, but the optimal timing and number of injections remain unknown...
Treatment of pulmonary arterial hypertension with circulating angiogenic cellsRachel Mirsky
Department of Medicine, University of California, San Francisco, San Francisco, California 94143, USA
Am J Physiol Lung Cell Mol Physiol 301:L12-9. 2011..Future studies should be geared toward either earlier therapeutic time points with varying doses of unmodified CACs or genetically modified cells as a means of delivery of factors to the pulmonary arterial circulation...
Diagnostic performance of cardiac magnetic resonance imaging in coronary artery diseaseJussi P Pärkkä
Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland
Clin Physiol Funct Imaging 30:89-97. 2010....
Determinants of coronary flow velocity reserve in healthy young menTuomas O Kiviniemi
Department of Clinical Physiology, Nuclear Medicine and PET, Turku University Hospital, Turku, Finland
Am J Physiol Heart Circ Physiol 291:H564-9. 2006..We found no relationship between CFVR and serum lipids or body mass index. We conclude that abdominal fat accumulation and low aerobic fitness are independently associated with CFVR in men...
Pravastatin-induced improvement in coronary reactivity and circulating ATP and ADP levels in young adults with type 1 diabetesTuomas O Kiviniemi
Department of Clinical Physiology, Turku University Hospital Turku, Finland
Front Physiol 3:338. 2012..This study provides a novel insight in purinergic mechanisms involved in pleiotropic effects of pravastatin...
Cardiac Function, Perfusion, Metabolism, and Innervation following Autologous Stem Cell Therapy for Acute ST-Elevation Myocardial Infarction. A FINCELL-INSIGHT Sub-Study with PET and MRIMaija T Mäki
Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital Turku, Finland
Front Physiol 3:6. 2012..However, no consistently better outcome was observed in the BMC-treated group compared to placebo...
Cardiomyocyte apoptosis after antegrade and retrograde cardioplegia during aortic valve surgeryTommi Vähäsilta
Department of Surgery, Turku University Hospital, University of Turku, Turku, Finland
Ann Thorac Surg 92:1351-7. 2011..We compared antegrade and retrograde cardioplegia in a randomized clinical trial to see whether it has effect on cardiomyocyte apoptosis and left ventricular function...
