Research Topics
| Hannu KoponenSummaryAffiliation: University of Kuopio Country: Finland Publications
| Collaborators
|
Detail Information
Publications
The prevalence and predictive value of individual criteria for metabolic syndrome in schizophrenia: a Northern Finland 1966 Birth Cohort StudyHannu J Koponen
Department of Psychiatry, University Hospital of Kuopio, Kuopio, Finland
World J Biol Psychiatry 11:262-7. 2010..8% of the patients. Reduced HDL cholesterol was the most specific criteria, with 95% specificity equalling a positive likelihood ratio of 9.78. Thus both the IDF and NCEP-ATPIII criteria may be equally useful in identifying MetS...- Schizophrenia and sudden cardiac death: a reviewHannu Koponen
Department of Psychiatry, University of Kuopio, Kuopio, Finland
Nord J Psychiatry 62:342-5. 2008..In addition, more studies on the role and prevalence of autonomic dysfunction in psychotic patients are needed... - No difference in insulin resistance and lipid levels between controls and adolescent subjects who later develop psychosisH Koponen
Department of Psychiatry, University of Kuopio and University Hospital of Kuopio, P O Box 1777, FIN 70211 Kuopio, Finland
Schizophr Res 104:31-5. 2008..There were no differences in the cardiometabolic variables, suggesting that psychotic episode is not preceded by glucose and lipid metabolism disturbances... - Insulin resistance and lipid levels in adolescents with familial risk for psychosisH Koponen
Department of Psychiatry, University of Kuopio, and Academy of Finland, Kuopio, Finland
Acta Psychiatr Scand 117:337-41. 2008..Type 2 diabetes and dyslipidemias co-occur frequently with schizophrenia. It is not known how common they are in adolescents with a familial risk for psychosis... 
Metabolic syndrome predisposes to depressive symptoms: a population-based 7-year follow-up studyHannu Koponen
Department of Psychiatry, University of Kuopio, and Kuopio University Hospital, Kuopio, Finland
J Clin Psychiatry 69:178-82. 2008....
Efficacy of duloxetine for the treatment of generalized anxiety disorder: implications for primary care physiciansHannu Koponen
University of Kuopio, Kuopio, Finland
Prim Care Companion J Clin Psychiatry 9:100-7. 2007..Clinical Trials Registration: ClinicalTrials.gov identifier NCT00122824...- Depressive symptoms and 10-year risk for cardiovascular morbidity and mortalityHannu Koponen
Department of Psychiatry, Kuopio University Hospital and University of Eastern Finland, Kuopio, Finland
World J Biol Psychiatry 11:834-9. 2010.... - Rates and previous disease history in old age suicideHannu J Koponen
Department of Psychiatry, University of Kuopio, Kuopio, Finland
Int J Geriatr Psychiatry 22:38-46. 2007..Since the absolute number of suicides in the elderly is expected to rise, more precise ways to identify potential risk factors for elderly suicides are needed... - Patterns of psychiatric hospitalizations in schizophrenic psychoses within the Northern Finland 1966 Birth CohortJouko Miettunen
Department of Psychiatry, University of Oulu, PO Box 5000, FIN 90014, Finland
Nord J Psychiatry 60:286-93. 2006..Although short hospitalization is recommended by several guidelines, there may be a group of patients with schizophrenic psychoses in which too short a hospitalization may lead to inadequate treatment response... - Predictors of schizophrenia: evidence from the Northern Finland 1966 Birth Cohort and other sourcesMatti Isohanni
Department of Psychiatry, University of Oulu, PO Box 5000, Finland
Br J Psychiatry Suppl 48:s4-7. 2005..Subtle motor, emotional, cognitive and behavioural abnormalities are often present in apparently healthy individuals who later develop schizophrenia, suggesting that some aspects of causation are established before overt psychosis... - Socio-demographic and clinical predictors of occupational status in schizophrenic psychoses--follow-up within the Northern Finland 1966 Birth CohortJouko Miettunen
Department of Psychiatry, University of Oulu, P O Box 5000, 90014 Oulun yliopisto, Finland
Psychiatry Res 150:217-25. 2007..Based on our findings, those who were single at time of their onset of illness probably need most support to retain their contacts to work life... - Are females at special risk of obesity if they become psychotic? The longitudinal Northern Finland 1966 Birth Cohort StudyHelinä Hakko
Oulu University Hospital, Department of Psychiatry, P O Box 26, 90029 Oulu University Hospital, Finland
Schizophr Res 84:15-9. 2006..These findings emphasize the importance of regular weight monitoring in clinical practice, especially in females with psychotic disorders... - Hyperlipidemia in persons using antipsychotic medication: a general population-based birth cohort studyKaisa Saari
Department of Psychiatry, University of Oulu, 90014 Oulu, Finland
J Clin Psychiatry 65:547-50. 2004..The results indicate an elevated risk of hyperlipidemia in persons using antipsychotic medication independent of the other risk factors assessed... - Use of antipsychotic medication and suicidality--the Northern Finland Birth Cohort 1966Ina Rissanen
Department of Psychiatry, Institute of Clinical Medicine, University of Oulu, Oulu, Finland
Hum Psychopharmacol 27:476-85. 2012..Our results suggest that one should take suicidal ideation into account when prescribing antipsychotic medication, especially for off-label use... - Prevalence of metabolic syndrome in subjects with melancholic and non-melancholic depressive symptoms. A Finnish population-based studyJussi Seppälä
Department of Psychiatry, South Savo Hospital District, Mikkeli, Finland
J Affect Disord 136:543-9. 2012.... - Association between duration of untreated psychosis and brain morphology in schizophrenia within the Northern Finland 1966 Birth CohortMatti Penttilä
University of Oulu, Institute of Clinical Medicine, Department of Psychiatry, P O Box 5000, FIN 90014 Oulu, Finland
Schizophr Res 123:145-52. 2010..Our aim was to analyze the relation between DUP and the brain structure in schizophrenia in the general population, after several years of illness... - Association between folate intake and melancholic depressive symptoms. A Finnish population-based studyJussi Seppälä
Department of Psychiatry, South Savo Hospital District, Mikkeli, Finland
J Affect Disord 138:473-8. 2012..An association between low blood folate levels and depressive symptoms (DS) has been reported in several epidemiological studies, but no studies have examined folate intake in melancholic or non-melancholic DS in population-based samples... - Rate of cannabis use disorders in clinical samples of patients with schizophrenia: a meta-analysisJohanna Koskinen
Department of Psychiatry, University of Oulu and Oulu University Hospital, PO Box 5000, FIN 90014, Oulu, Finland
Schizophr Bull 36:1115-30. 2010..Our aim was to review recent studies and estimate the rate of cannabis use disorders (CUDs) in schizophrenia, as well as to examine the factors affecting this rate... - Effect of menopause and use of contraceptives/hormone therapy on association of C-reactive protein and depression: a population-based studyTimo Liukkonen
Department of Psychiatry, Savonlinna Central Hospital, Savonlinna, Finland Institute of Health Sciences, University of Oulu, University of Oulu, Finland
J Psychosom Res 68:573-9. 2010.... - Depressive symptomatology is associated with decreased interleukin-1 beta and increased interleukin-1 receptor antagonist levels in malesYrjö Ovaskainen
Department of Psychiatry, South Savo Hospital District, Moisio Hospital, FIN 50520 Mikkeli, Finland
Psychiatry Res 167:73-9. 2009..The elevated IL-1RA-levels and IL-1RA/IL-1 beta ratio suggest a role for cytokines in the pathogenesis of depression. The higher IL-1RA levels may reflect an endogenous repairing process against depression... - Developmental precursors of psychosisMatti Isohanni
Department of Psychiatry, Faculty of Medicine, University of Oulu, Oulu University Central Hospital, PO Box 5000, FIN 90014 Oulu, Finland
Curr Psychiatry Rep 6:168-75. 2004..No powerful risk factor, premorbid sign, or risk indicator has been identified that is useful for prediction of psychoses in the general population... - Psychological distress measured by the GHQ-12 and mortality: a prospective population-based studyPekka Johannes Puustinen
Centre for Social and Health Services, Kuopio, Finland
Scand J Public Health 39:577-81. 2011.... - Predictors of schizophrenia--a reviewPirjo Maki
Department of Psychiatry, University of Oulu, PO Box 5000, FIN 90014 University of Oulu, Finland
Br Med Bull 73:1-15. 2005.... - Psychological distress and C-reactive protein: do health behaviours and pathophysiological factors modify the association?Pekka Johannes Puustinen
Centre for Social and Health Services, Kuopio, Finland
Eur Arch Psychiatry Clin Neurosci 261:277-84. 2011..CRP could be an important pathophysiological mechanism through which psychological factors are associated with cardiovascular disease... - Weight gain and glucose and lipid metabolism disturbances during antipsychotic medication: a reviewHannu Koponen
Department of Psychiatry, University of Oulu, Oulu, Finland
Eur Arch Psychiatry Clin Neurosci 252:294-8. 2002.... - How to use bibliometric methods in evaluation of scientific research? An example from Finnish schizophrenia researchJohanna Koskinen
Department of Psychiatry, University of Oulu and Oulu University Hospital, Finland
Nord J Psychiatry 62:136-43. 2008..According to our experience, these methods can be used as an evaluation instrument in research together with other methods, such as expert opinions and panels... - Outcome of patients after market withdrawal of thioridazine: a retrospective analysis in a nationwide cohortMaija Purhonen
Department of Psychiatry, Kuopio University Hospital, Kuopio, Finland
Pharmacoepidemiol Drug Saf 21:1227-31. 2012..Thioridazine is a first-generation antipsychotic drug that was withdrawn from the market worldwide in 2005. The outcome of clinically stable schizophrenia patients who used thioridazine before market withdrawal was evaluated... - Association between the duration of untreated psychosis and short- and long-term outcome in schizophrenia within the Northern Finland 1966 Birth CohortMatti Penttilä
University of Oulu, Institute of Clinical Medicine, Department of Psychiatry, Oulu, Finland
Schizophr Res 143:3-10. 2013..However, the associations between DUP and outcomes, particularly in later course of illness, remain unclear. Our aim was to explore the associations between DUP and short- and long-term outcomes in schizophrenia... - Agreement between self-reported and pharmacy data on medication use in the Northern Finland 1966 Birth CohortMarianne Haapea
Department of Psychiatry, University of Oulu and Oulu University Hospital, Oulu, Finland
Int J Methods Psychiatr Res 19:88-96. 2010..To compare self-reported (SR) medication use and pharmacy data for major psychoactive medications and three classes of medications used for different indications, and to determine the socio-economic factors associated with the congruence... - Childhood central nervous system infections and risk for schizophreniaHannu Koponen
Department of Psychiatry, University of Oulu, PO Box 5000, 90014 Oulu, Finland
Eur Arch Psychiatry Clin Neurosci 254:9-13. 2004..Our results suggest that viral CNS infections during childhood may have a role as a risk factor for schizophrenia. Their role may be modest at the population level due to their relative rareness... - Negative symptoms and their predictors in schizophrenia within the Northern Finland 1966 Birth CohortJussi Mäkinen
Department of Psychiatry, University of Oulu, Finland
Psychiatry Res 178:121-5. 2010..These findings are new. However, we were not able to identify any major premorbid phenotype or endophenotype predicting negative symptoms which support the view that negative symptoms might mainly be a specific part of the illness... - Association of depressive symptoms with impaired glucose regulation, screen-detected, and previously known type 2 diabetes: findings from the Finnish D2D SurveyPekka Mäntyselkä
School of Medicine, Unit of Primary Health Care, University of Eastern Finland, Kuopio, Finland
Diabetes Care 34:71-6. 2011..To study the association between impaired glucose regulation (IGR), screen-detected type 2 diabetes, and previously known diabetes and depressive symptoms... - A 4-fold risk of metabolic syndrome in patients with schizophrenia: the Northern Finland 1966 Birth Cohort studyKaisa M Saari
Department of Psychiatry, University of Oulu, PO Box 5000, 90014 Oulu, Finland
J Clin Psychiatry 66:559-63. 2005..Our objective was to study the prevalence of metabolic syndrome in a population-based birth cohort... - Reversal of antipsychotic-induced weight gain during quetiapine treatmentHannu Koponen
Department of Psychiatry, University of Oulu, Oulu, Finland
Int Clin Psychopharmacol 18:355-6. 2003..We report two patients who gained weight during previous antipsychotic treatment but who lost weight when shifted to quetiapine... - Suicide after hospitalization in the elderly: a population based study of suicides in Northern Finland between 1988-2003Kaisa Karvonen
Department of Psychiatry, Oulu University Hospital, Finland
Int J Geriatr Psychiatry 23:135-41. 2008..The lack of information is most apparent in the oldest old (individuals over 75 years)... - Psychiatric drug trials and placeboHannu Koponen
Department of Psychiatry, University of Oulu, Finland
Nord J Psychiatry 59:233-7. 2005..In this systematic review, the present guidelines for developing new compounds for psychiatric disorders are discussed... - Deramciclane in the treatment of generalized anxiety disorder: a placebo-controlled, double-blind, dose-finding studyHannu Naukkarinen
Department of Psychiatry, University of Helsinki, Box 320 Lapinlahdentie, FIN 00180, HUCH, Helsinki, Finland
Eur Neuropsychopharmacol 15:617-23. 2005..Deramciclane was safe and well-tolerated up to the 60 mg/day dose over an 8-week period... - Sedative drug use in the home-dwelling elderlyTarja A Linjakumpu
Department of Psychiatry, Oulu University, Oulu University Hospital, Isokayu 50 C 55, 90100 Oulu, Finland
Ann Pharmacother 38:2017-22. 2004..The elderly use more sedatives than other populations. Reports on the sedative load of drugs and their associations with health items are scarce...