Hannu Koponen

Summary

Affiliation: University of Kuopio
Country: Finland

Publications

  1. ncbi Rates and previous disease history in old age suicide
    Hannu J Koponen
    Department of Psychiatry, University of Kuopio, Kuopio, Finland
    Int J Geriatr Psychiatry 22:38-46. 2007
  2. ncbi Metabolic syndrome predisposes to depressive symptoms: a population-based 7-year follow-up study
    Hannu Koponen
    Department of Psychiatry, University of Kuopio, and Kuopio University Hospital, Kuopio, Finland
    J Clin Psychiatry 69:178-82. 2008
  3. doi Insulin resistance and lipid levels in adolescents with familial risk for psychosis
    H Koponen
    Department of Psychiatry, University of Kuopio, and Academy of Finland, Kuopio, Finland
    Acta Psychiatr Scand 117:337-41. 2008
  4. doi Depressive symptoms and 10-year risk for cardiovascular morbidity and mortality
    Hannu Koponen
    Department of Psychiatry, Kuopio University Hospital and University of Eastern Finland, Kuopio, Finland
    World J Biol Psychiatry 11:834-9. 2010
  5. doi No difference in insulin resistance and lipid levels between controls and adolescent subjects who later develop psychosis
    H Koponen
    Department of Psychiatry, University of Kuopio and University Hospital of Kuopio, P O Box 1777, FIN 70211 Kuopio, Finland
    Schizophr Res 104:31-5. 2008
  6. doi Schizophrenia and sudden cardiac death: a review
    Hannu Koponen
    Department of Psychiatry, University of Kuopio, Kuopio, Finland
    Nord J Psychiatry 62:342-5. 2008
  7. pmc Efficacy of duloxetine for the treatment of generalized anxiety disorder: implications for primary care physicians
    Hannu Koponen
    University of Kuopio, Kuopio, Finland
    Prim Care Companion J Clin Psychiatry 9:100-7. 2007
  8. doi The prevalence and predictive value of individual criteria for metabolic syndrome in schizophrenia: a Northern Finland 1966 Birth Cohort Study
    Hannu J Koponen
    Department of Psychiatry, University Hospital of Kuopio, Kuopio, Finland
    World J Biol Psychiatry 11:262-7. 2010
  9. ncbi Patterns of psychiatric hospitalizations in schizophrenic psychoses within the Northern Finland 1966 Birth Cohort
    Jouko Miettunen
    Department of Psychiatry, University of Oulu, PO Box 5000, FIN 90014, Finland
    Nord J Psychiatry 60:286-93. 2006
  10. ncbi Socio-demographic and clinical predictors of occupational status in schizophrenic psychoses--follow-up within the Northern Finland 1966 Birth Cohort
    Jouko Miettunen
    Department of Psychiatry, University of Oulu, P O Box 5000, 90014 Oulun yliopisto, Finland
    Psychiatry Res 150:217-25. 2007

Collaborators

Detail Information

Publications39

  1. ncbi Rates and previous disease history in old age suicide
    Hannu J Koponen
    Department of Psychiatry, University of Kuopio, Kuopio, Finland
    Int J Geriatr Psychiatry 22:38-46. 2007
    ..Since the absolute number of suicides in the elderly is expected to rise, more precise ways to identify potential risk factors for elderly suicides are needed...
  2. ncbi Metabolic syndrome predisposes to depressive symptoms: a population-based 7-year follow-up study
    Hannu Koponen
    Department of Psychiatry, University of Kuopio, and Kuopio University Hospital, Kuopio, Finland
    J Clin Psychiatry 69:178-82. 2008
    ....
  3. doi Insulin resistance and lipid levels in adolescents with familial risk for psychosis
    H Koponen
    Department of Psychiatry, University of Kuopio, and Academy of Finland, Kuopio, Finland
    Acta Psychiatr Scand 117:337-41. 2008
    ..Type 2 diabetes and dyslipidemias co-occur frequently with schizophrenia. It is not known how common they are in adolescents with a familial risk for psychosis...
  4. doi Depressive symptoms and 10-year risk for cardiovascular morbidity and mortality
    Hannu Koponen
    Department of Psychiatry, Kuopio University Hospital and University of Eastern Finland, Kuopio, Finland
    World J Biol Psychiatry 11:834-9. 2010
    ....
  5. doi No difference in insulin resistance and lipid levels between controls and adolescent subjects who later develop psychosis
    H Koponen
    Department of Psychiatry, University of Kuopio and University Hospital of Kuopio, P O Box 1777, FIN 70211 Kuopio, Finland
    Schizophr Res 104:31-5. 2008
    ..There were no differences in the cardiometabolic variables, suggesting that psychotic episode is not preceded by glucose and lipid metabolism disturbances...
  6. doi Schizophrenia and sudden cardiac death: a review
    Hannu Koponen
    Department of Psychiatry, University of Kuopio, Kuopio, Finland
    Nord J Psychiatry 62:342-5. 2008
    ..In addition, more studies on the role and prevalence of autonomic dysfunction in psychotic patients are needed...
  7. pmc Efficacy of duloxetine for the treatment of generalized anxiety disorder: implications for primary care physicians
    Hannu Koponen
    University of Kuopio, Kuopio, Finland
    Prim Care Companion J Clin Psychiatry 9:100-7. 2007
    ..Clinical Trials Registration: ClinicalTrials.gov identifier NCT00122824...
  8. doi The prevalence and predictive value of individual criteria for metabolic syndrome in schizophrenia: a Northern Finland 1966 Birth Cohort Study
    Hannu J Koponen
    Department of Psychiatry, University Hospital of Kuopio, Kuopio, Finland
    World J Biol Psychiatry 11:262-7. 2010
    ..8% of the patients. Reduced HDL cholesterol was the most specific criteria, with 95% specificity equalling a positive likelihood ratio of 9.78. Thus both the IDF and NCEP-ATPIII criteria may be equally useful in identifying MetS...
  9. ncbi Patterns of psychiatric hospitalizations in schizophrenic psychoses within the Northern Finland 1966 Birth Cohort
    Jouko Miettunen
    Department of Psychiatry, University of Oulu, PO Box 5000, FIN 90014, Finland
    Nord J Psychiatry 60:286-93. 2006
    ..Although short hospitalization is recommended by several guidelines, there may be a group of patients with schizophrenic psychoses in which too short a hospitalization may lead to inadequate treatment response...
  10. ncbi Socio-demographic and clinical predictors of occupational status in schizophrenic psychoses--follow-up within the Northern Finland 1966 Birth Cohort
    Jouko Miettunen
    Department of Psychiatry, University of Oulu, P O Box 5000, 90014 Oulun yliopisto, Finland
    Psychiatry Res 150:217-25. 2007
    ..Based on our findings, those who were single at time of their onset of illness probably need most support to retain their contacts to work life...
  11. ncbi Are females at special risk of obesity if they become psychotic? The longitudinal Northern Finland 1966 Birth Cohort Study
    Helinä Hakko
    Oulu University Hospital, Department of Psychiatry, P O Box 26, 90029 Oulu University Hospital, Finland
    Schizophr Res 84:15-9. 2006
    ..These findings emphasize the importance of regular weight monitoring in clinical practice, especially in females with psychotic disorders...
  12. ncbi Predictors of schizophrenia: evidence from the Northern Finland 1966 Birth Cohort and other sources
    Matti Isohanni
    Department of Psychiatry, University of Oulu, PO Box 5000, Finland
    Br J Psychiatry Suppl 48:s4-7. 2005
    ..Subtle motor, emotional, cognitive and behavioural abnormalities are often present in apparently healthy individuals who later develop schizophrenia, suggesting that some aspects of causation are established before overt psychosis...
  13. doi Association between the duration of untreated psychosis and short- and long-term outcome in schizophrenia within the Northern Finland 1966 Birth Cohort
    Matti Penttilä
    University of Oulu, Institute of Clinical Medicine, Department of Psychiatry, Oulu, Finland
    Schizophr Res 143:3-10. 2013
    ..However, the associations between DUP and outcomes, particularly in later course of illness, remain unclear. Our aim was to explore the associations between DUP and short- and long-term outcomes in schizophrenia...
  14. ncbi Hyperlipidemia in persons using antipsychotic medication: a general population-based birth cohort study
    Kaisa Saari
    Department of Psychiatry, University of Oulu, 90014 Oulu, Finland
    J Clin Psychiatry 65:547-50. 2004
    ..We studied the prevalence of hyperlipidemia in subjects who did and did not take antipsychotic medication in a prospective, general population-based birth cohort...
  15. doi Use of antipsychotic medication and suicidality--the Northern Finland Birth Cohort 1966
    Ina Rissanen
    Department of Psychiatry, Institute of Clinical Medicine, University of Oulu, Oulu, Finland
    Hum Psychopharmacol 27:476-85. 2012
    ..Our results suggest that one should take suicidal ideation into account when prescribing antipsychotic medication, especially for off-label use...
  16. doi Prevalence of metabolic syndrome in subjects with melancholic and non-melancholic depressive symptoms. A Finnish population-based study
    Jussi Seppälä
    Department of Psychiatry, South Savo Hospital District, Mikkeli, Finland
    J Affect Disord 136:543-9. 2012
    ....
  17. doi Association between duration of untreated psychosis and brain morphology in schizophrenia within the Northern Finland 1966 Birth Cohort
    Matti Penttilä
    University of Oulu, Institute of Clinical Medicine, Department of Psychiatry, P O Box 5000, FIN 90014 Oulu, Finland
    Schizophr Res 123:145-52. 2010
    ..Our aim was to analyze the relation between DUP and the brain structure in schizophrenia in the general population, after several years of illness...
  18. ncbi Negative symptoms and their predictors in schizophrenia within the Northern Finland 1966 Birth Cohort
    Jussi Mäkinen
    Department of Psychiatry, University of Oulu, Finland
    Psychiatry Res 178:121-5. 2010
    ..These findings are new. However, we were not able to identify any major premorbid phenotype or endophenotype predicting negative symptoms which support the view that negative symptoms might mainly be a specific part of the illness...
  19. doi Association between folate intake and melancholic depressive symptoms. A Finnish population-based study
    Jussi Seppälä
    Department of Psychiatry, South Savo Hospital District, Mikkeli, Finland
    J Affect Disord 138:473-8. 2012
    ..An association between low blood folate levels and depressive symptoms (DS) has been reported in several epidemiological studies, but no studies have examined folate intake in melancholic or non-melancholic DS in population-based samples...
  20. pmc Rate of cannabis use disorders in clinical samples of patients with schizophrenia: a meta-analysis
    Johanna Koskinen
    Department of Psychiatry, University of Oulu and Oulu University Hospital, PO Box 5000, FIN 90014, Oulu, Finland
    Schizophr Bull 36:1115-30. 2010
    ..Our aim was to review recent studies and estimate the rate of cannabis use disorders (CUDs) in schizophrenia, as well as to examine the factors affecting this rate...
  21. doi Effect of menopause and use of contraceptives/hormone therapy on association of C-reactive protein and depression: a population-based study
    Timo Liukkonen
    Department of Psychiatry, Savonlinna Central Hospital, Savonlinna, Finland Institute of Health Sciences, University of Oulu, University of Oulu, Finland
    J Psychosom Res 68:573-9. 2010
    ....
  22. ncbi Predictors of schizophrenia--a review
    Pirjo Maki
    Department of Psychiatry, University of Oulu, PO Box 5000, FIN 90014 University of Oulu, Finland
    Br Med Bull 73:1-15. 2005
    ....
  23. doi Depressive symptomatology is associated with decreased interleukin-1 beta and increased interleukin-1 receptor antagonist levels in males
    Yrjö Ovaskainen
    Department of Psychiatry, South Savo Hospital District, Moisio Hospital, FIN 50520 Mikkeli, Finland
    Psychiatry Res 167:73-9. 2009
    ..The elevated IL-1RA-levels and IL-1RA/IL-1 beta ratio suggest a role for cytokines in the pathogenesis of depression. The higher IL-1RA levels may reflect an endogenous repairing process against depression...
  24. doi Psychological distress measured by the GHQ-12 and mortality: a prospective population-based study
    Pekka Johannes Puustinen
    Centre for Social and Health Services, Kuopio, Finland
    Scand J Public Health 39:577-81. 2011
    ....
  25. ncbi Developmental precursors of psychosis
    Matti Isohanni
    Department of Psychiatry, Faculty of Medicine, University of Oulu, Oulu University Central Hospital, PO Box 5000, FIN 90014 Oulu, Finland
    Curr Psychiatry Rep 6:168-75. 2004
    ..No powerful risk factor, premorbid sign, or risk indicator has been identified that is useful for prediction of psychoses in the general population...
  26. doi Psychological distress and C-reactive protein: do health behaviours and pathophysiological factors modify the association?
    Pekka Johannes Puustinen
    Centre for Social and Health Services, Kuopio, Finland
    Eur Arch Psychiatry Clin Neurosci 261:277-84. 2011
    ..CRP could be an important pathophysiological mechanism through which psychological factors are associated with cardiovascular disease...
  27. ncbi Weight gain and glucose and lipid metabolism disturbances during antipsychotic medication: a review
    Hannu Koponen
    Department of Psychiatry, University of Oulu, Oulu, Finland
    Eur Arch Psychiatry Clin Neurosci 252:294-8. 2002
    ....
  28. ncbi How to use bibliometric methods in evaluation of scientific research? An example from Finnish schizophrenia research
    Johanna Koskinen
    Department of Psychiatry, University of Oulu and Oulu University Hospital, Finland
    Nord J Psychiatry 62:136-43. 2008
    ..According to our experience, these methods can be used as an evaluation instrument in research together with other methods, such as expert opinions and panels...
  29. doi Outcome of patients after market withdrawal of thioridazine: a retrospective analysis in a nationwide cohort
    Maija Purhonen
    Department of Psychiatry, Kuopio University Hospital, Kuopio, Finland
    Pharmacoepidemiol Drug Saf 21:1227-31. 2012
    ..Thioridazine is a first-generation antipsychotic drug that was withdrawn from the market worldwide in 2005. The outcome of clinically stable schizophrenia patients who used thioridazine before market withdrawal was evaluated...
  30. ncbi Agreement between self-reported and pharmacy data on medication use in the Northern Finland 1966 Birth Cohort
    Marianne Haapea
    Department of Psychiatry, University of Oulu and Oulu University Hospital, Oulu, Finland
    Int J Methods Psychiatr Res 19:88-96. 2010
    ..To compare self-reported (SR) medication use and pharmacy data for major psychoactive medications and three classes of medications used for different indications, and to determine the socio-economic factors associated with the congruence...
  31. ncbi Childhood central nervous system infections and risk for schizophrenia
    Hannu Koponen
    Department of Psychiatry, University of Oulu, PO Box 5000, 90014 Oulu, Finland
    Eur Arch Psychiatry Clin Neurosci 254:9-13. 2004
    ..Our results suggest that viral CNS infections during childhood may have a role as a risk factor for schizophrenia. Their role may be modest at the population level due to their relative rareness...
  32. pmc Association of depressive symptoms with impaired glucose regulation, screen-detected, and previously known type 2 diabetes: findings from the Finnish D2D Survey
    Pekka Mäntyselkä
    School of Medicine, Unit of Primary Health Care, University of Eastern Finland, Kuopio, Finland
    Diabetes Care 34:71-6. 2011
    ..To study the association between impaired glucose regulation (IGR), screen-detected type 2 diabetes, and previously known diabetes and depressive symptoms...
  33. ncbi A 4-fold risk of metabolic syndrome in patients with schizophrenia: the Northern Finland 1966 Birth Cohort study
    Kaisa M Saari
    Department of Psychiatry, University of Oulu, PO Box 5000, 90014 Oulu, Finland
    J Clin Psychiatry 66:559-63. 2005
    ..Our objective was to study the prevalence of metabolic syndrome in a population-based birth cohort...
  34. doi Disordered semantic activation in disorganized discourse in schizophrenia: a new pragma-linguistic tool for structure and meaning reconstruction
    Pertti Hella
    Department of Psychiatry, Kuopio University Hospital, Kuopio, Finland
    Int J Lang Commun Disord 48:320-8. 2013
    ..Studies of language processing have demonstrated that semantic activation in schizophrenia is often disordered and, moreover, the ability to use contextual cues is impaired...
  35. ncbi Reversal of antipsychotic-induced weight gain during quetiapine treatment
    Hannu Koponen
    Department of Psychiatry, University of Oulu, Oulu, Finland
    Int Clin Psychopharmacol 18:355-6. 2003
    ..We report two patients who gained weight during previous antipsychotic treatment but who lost weight when shifted to quetiapine...
  36. ncbi Suicide after hospitalization in the elderly: a population based study of suicides in Northern Finland between 1988-2003
    Kaisa Karvonen
    Department of Psychiatry, Oulu University Hospital, Finland
    Int J Geriatr Psychiatry 23:135-41. 2008
    ..The lack of information is most apparent in the oldest old (individuals over 75 years)...
  37. ncbi Deramciclane in the treatment of generalized anxiety disorder: a placebo-controlled, double-blind, dose-finding study
    Hannu Naukkarinen
    Department of Psychiatry, University of Helsinki, Box 320 Lapinlahdentie, FIN 00180, HUCH, Helsinki, Finland
    Eur Neuropsychopharmacol 15:617-23. 2005
    ..Deramciclane was safe and well-tolerated up to the 60 mg/day dose over an 8-week period...
  38. ncbi Psychiatric drug trials and placebo
    Hannu Koponen
    Department of Psychiatry, University of Oulu, Finland
    Nord J Psychiatry 59:233-7. 2005
    ..In this systematic review, the present guidelines for developing new compounds for psychiatric disorders are discussed...
  39. ncbi Sedative drug use in the home-dwelling elderly
    Tarja A Linjakumpu
    Department of Psychiatry, Oulu University, Oulu University Hospital, Isokayu 50 C 55, 90100 Oulu, Finland
    Ann Pharmacother 38:2017-22. 2004
    ..The elderly use more sedatives than other populations. Reports on the sedative load of drugs and their associations with health items are scarce...