Research Topics
Species | M KomulainenSummaryAffiliation: University of Kuopio Country: Finland Publications
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Detail Information
Publications
Prevention of femoral and lumbar bone loss with hormone replacement therapy and vitamin D3 in early postmenopausal women: a population-based 5-year randomized trialM Komulainen
Department of Obstetrics and Gynecology, Kuopio University Hospital, University of Kuopio, Finland
J Clin Endocrinol Metab 84:546-52. 1999..The data suggest that low dose vitamin D3 supplementation does not prevent bone loss in healthy, nonosteoporotic, early postmenopausal women, and it confers no benefit additional to that of HRT alone...
HRT and Vit D in prevention of non-vertebral fractures in postmenopausal women; a 5 year randomized trialM H Komulainen
Department of Obstetrics and Gynecology, Kuopio University Hospital, Finland
Maturitas 31:45-54. 1998..We investigated the incidence of new non-vertebral fractures during HRT or low-dose vitamin (Vit) D3 supplementation in a 5-year prospective trial...
HRT and Vit D in prevention of non-vertebral fractures in postmenopausal women; a 5 year randomized trialMarja H Komulainen
Department of Obstetrics and Gynecology, Kuopio University Hospital, Kuopio, Finland
Maturitas 61:85-94. 2008..CONCLUSIONS: This study is the first prospective trial confirming the beneficial effect of HRT on prevention of peripheral fractures in non-osteoporotic postmenopausal women. The effect of low-dose Vit D remains to be proved...
Biochemical bone markers and bone mineral density during postmenopausal hormone replacement therapy with and without vitamin D3: a prospective, controlled, randomized studyA M Heikkinen
Department of Obstetrics and Gynecology, University Hospital of Kuopio, Finland
J Clin Endocrinol Metab 82:2476-82. 1997..Low dose vitamin D treatment, however, seems to have only marginal effects on bone metabolism in early postmenopausal healthy women...
Identification of early postmenopausal women with no bone response to HRT: results of a five-year clinical trialM Komulainen
Department of Obstetrics and Gynecology, Kuopio University Hospital, Finland
Osteoporos Int 11:211-8. 2000..Repeated serum FSH, estradiol and alkaline phosphatase measurements during the first months of long-term HRT may be helpful in identifying the women with no bone response to HRT...
The protective effect of hormone-replacement therapy on fracture risk is modulated by estrogen receptor alpha genotype in early postmenopausal womenT Salmen
Department of Biochemistry, University of Kuopio, Finland
J Bone Miner Res 15:2479-86. 2000..The results suggest that the pp genotype is a relatively hormone-insensitive genotype, and it appears that women with the P allele may benefit more from the protective effect of HRT on fracture risk than women with the pp genotype...
Postmenopausal hormone replacement therapy and autoantibodies against oxidized LDLA M Heikkinen
Kuopio University Hospital, Finland
Maturitas 29:155-61. 1998..The antioxidant effect and inhibition of LDL oxidation may be one of the cardioprotective mechanisms of postmenopausal estrogen therapy...
