Pirkko Liisa Kellokumpu-Lehtinen

Summary

Affiliation: University of Tampere
Country: Finland

Publications

  1. doi request reprint 2-Weekly versus 3-weekly docetaxel to treat castration-resistant advanced prostate cancer: a randomised, phase 3 trial
    Pirkko Liisa Kellokumpu-Lehtinen
    Department of Oncology, Tampere University Hospital, Tampere, Finland
    Lancet Oncol 14:117-24. 2013
  2. ncbi request reprint Toxicity in patients receiving adjuvant docetaxel + hormonal treatment after radical radiotherapy for intermediate or high-risk prostate cancer: a preplanned safety report of the SPCG-13 trial
    P L Kellokumpu-Lehtinen
    Department of Oncology and Radiotherapy, Tampere University Hospital, Tampere, Finland
    Prostate Cancer Prostatic Dis 15:303-7. 2012
  3. doi request reprint Anaemia: a rare but neglected problem among Finnish patients receiving chemotherapy for solid tumours
    Pirkko Liisa Kellokumpu-Lehtinen
    Department of Oncology, University of Tampere and Tampere University Hospital, B O X 607, FIN 33101, Tampere, Finland
    Support Care Cancer 19:149-53. 2011
  4. ncbi request reprint Cost-effectiveness of intensive adjuvant chemotherapy for high-risk breast cancer: is tailored and dose-escalated chemotherapy with growth factor support (GFS) more costly and less effective than marrow-supported high-dose chemotherapy - results from a ra
    P Kellokumpu-Lehtinen
    Department of Oncology, Tampere University Hospital, Tampere, Finland
    Acta Oncol 46:146-52. 2007
  5. ncbi request reprint [Cancer and sexuality]
    Pirkko Kellokumpu-Lehtinen
    TAYS n syöpätautien klinikka 36280 Pikonlinna
    Duodecim 119:237-46. 2003
  6. doi request reprint Adjuvant capecitabine, docetaxel, cyclophosphamide, and epirubicin for early breast cancer: final analysis of the randomized FinXX trial
    Heikki Joensuu
    Department of Oncology, Helsinki University Central Hospital, Haartmaninkatu 4, PO Box 180, FIN 00029 Helsinki, Finland
    J Clin Oncol 30:11-8. 2012
  7. ncbi request reprint Adjuvant docetaxel or vinorelbine with or without trastuzumab for breast cancer
    Heikki Joensuu
    Department of Oncology, Helsinki University Central Hospital, Helsinki, Finland
    N Engl J Med 354:809-20. 2006
  8. doi request reprint Diffusion-weighted MRI in early chemotherapy response evaluation of patients with diffuse large B-cell lymphoma--a pilot study: comparison with 2-deoxy-2-fluoro- D-glucose-positron emission tomography/computed tomography
    Xingchen Wu
    Department of Oncology, Tampere University Hospital, Teiskontie 35, Tampere, Finland
    NMR Biomed 24:1181-90. 2011
  9. doi request reprint PET imaging in a longitudinal non-Hodgkin's lymphoma study: association with tumor volume
    Maija Rossi
    Medical Imaging Centre, Department of Radiology, Tampere University Hospital, Tampere, Finland
    Acta Radiol 52:995-1002. 2011
  10. doi request reprint ADC measurements in diffuse large B-cell lymphoma and follicular lymphoma: a DWI and cellularity study
    Xingchen Wu
    Department of Oncology, Tampere University Hospital, Tampere, Finland
    Eur J Radiol 82:e158-64. 2013

Collaborators

Detail Information

Publications41

  1. doi request reprint 2-Weekly versus 3-weekly docetaxel to treat castration-resistant advanced prostate cancer: a randomised, phase 3 trial
    Pirkko Liisa Kellokumpu-Lehtinen
    Department of Oncology, Tampere University Hospital, Tampere, Finland
    Lancet Oncol 14:117-24. 2013
    ....
  2. ncbi request reprint Toxicity in patients receiving adjuvant docetaxel + hormonal treatment after radical radiotherapy for intermediate or high-risk prostate cancer: a preplanned safety report of the SPCG-13 trial
    P L Kellokumpu-Lehtinen
    Department of Oncology and Radiotherapy, Tampere University Hospital, Tampere, Finland
    Prostate Cancer Prostatic Dis 15:303-7. 2012
    ..To increase the recurrence-free and overall survival, we conducted an adjuvant, randomized trial using docetaxel (T) in PC patients (Scandinavian Prostate Cancer Group trial 13)...
  3. doi request reprint Anaemia: a rare but neglected problem among Finnish patients receiving chemotherapy for solid tumours
    Pirkko Liisa Kellokumpu-Lehtinen
    Department of Oncology, University of Tampere and Tampere University Hospital, B O X 607, FIN 33101, Tampere, Finland
    Support Care Cancer 19:149-53. 2011
    ..We assessed the frequency of anaemia and the frequency with which it was diagnosed and treated in different types of solid tumours treated at outpatient chemotherapy policlinics...
  4. ncbi request reprint Cost-effectiveness of intensive adjuvant chemotherapy for high-risk breast cancer: is tailored and dose-escalated chemotherapy with growth factor support (GFS) more costly and less effective than marrow-supported high-dose chemotherapy - results from a ra
    P Kellokumpu-Lehtinen
    Department of Oncology, Tampere University Hospital, Tampere, Finland
    Acta Oncol 46:146-52. 2007
    ....
  5. ncbi request reprint [Cancer and sexuality]
    Pirkko Kellokumpu-Lehtinen
    TAYS n syöpätautien klinikka 36280 Pikonlinna
    Duodecim 119:237-46. 2003
  6. doi request reprint Adjuvant capecitabine, docetaxel, cyclophosphamide, and epirubicin for early breast cancer: final analysis of the randomized FinXX trial
    Heikki Joensuu
    Department of Oncology, Helsinki University Central Hospital, Haartmaninkatu 4, PO Box 180, FIN 00029 Helsinki, Finland
    J Clin Oncol 30:11-8. 2012
    ..It is not known whether integration of capecitabine into an adjuvant regimen that contains a taxane, an anthracycline, and cyclophosphamide improves outcome in early breast cancer...
  7. ncbi request reprint Adjuvant docetaxel or vinorelbine with or without trastuzumab for breast cancer
    Heikki Joensuu
    Department of Oncology, Helsinki University Central Hospital, Helsinki, Finland
    N Engl J Med 354:809-20. 2006
    ..We compared docetaxel with vinorelbine for the adjuvant treatment of early breast cancer. Women with tumors that overexpressed HER2/neu were also assigned to receive concomitant treatment with trastuzumab or no such treatment...
  8. doi request reprint Diffusion-weighted MRI in early chemotherapy response evaluation of patients with diffuse large B-cell lymphoma--a pilot study: comparison with 2-deoxy-2-fluoro- D-glucose-positron emission tomography/computed tomography
    Xingchen Wu
    Department of Oncology, Tampere University Hospital, Teiskontie 35, Tampere, Finland
    NMR Biomed 24:1181-90. 2011
    ..05). In conclusion, the results of DWI in combination with whole-body MRI were comparable with those of integrated PET/CT...
  9. doi request reprint PET imaging in a longitudinal non-Hodgkin's lymphoma study: association with tumor volume
    Maija Rossi
    Medical Imaging Centre, Department of Radiology, Tampere University Hospital, Tampere, Finland
    Acta Radiol 52:995-1002. 2011
    ..Instead of morphological images, positron emission tomography (PET) shows metabolic information that is connected to tumor activity, cell proliferation rate, and, thus, prognosis...
  10. doi request reprint ADC measurements in diffuse large B-cell lymphoma and follicular lymphoma: a DWI and cellularity study
    Xingchen Wu
    Department of Oncology, Tampere University Hospital, Tampere, Finland
    Eur J Radiol 82:e158-64. 2013
    ....
  11. doi request reprint Fluorouracil, epirubicin, and cyclophosphamide with either docetaxel or vinorelbine, with or without trastuzumab, as adjuvant treatments of breast cancer: final results of the FinHer Trial
    Heikki Joensuu
    Department of Oncology, Helsinki University Central Hospital, Helsinki, Finland
    J Clin Oncol 27:5685-92. 2009
    ..Efficacy and long-term safety of a short course of adjuvant trastuzumab administered concomitantly with chemotherapy for human epidermal growth factor receptor 2 (HER2) -positive cancer are unknown...
  12. doi request reprint Effect of social support on changes in quality of life in early breast cancer patients: a longitudinal study
    Päivi Salonen
    Administration Centre, Tampere University Hospital, Tampere, Finland
    Scand J Caring Sci 27:396-405. 2013
    ..Researchers have examined social support and its relations with QOL overall, but less is known about effects of social support on changes in QOL...
  13. ncbi request reprint Biweekly docetaxel is better tolerated than conventional three-weekly dosing for advanced hormone-refractory prostate cancer
    Petteri Hervonen
    Tampere University Hospital, Tampere, Finland
    Anticancer Res 32:953-6. 2012
    ..Therefore, we compared biweekly to triweekly docetaxel as first- or second-line chemotherapy for advanced HRPC in this prospective randomized multicenter trial...
  14. doi request reprint Outcome of patients with HER2-positive breast cancer treated with or without adjuvant trastuzumab in the Finland Capecitabine Trial (FinXX)
    Heikki Joensuu
    Department of Oncology, Helsinki University Central Hospital, Helsinki, Finland
    Acta Oncol 53:186-94. 2014
    ..Conclusion. Adjuvant trastuzumab improves RFS of patients treated with TX-CEX or T-CEF. Few patients had cardiac failure. ..
  15. doi request reprint Individual face-to-face support and quality of life in patients with breast cancer
    Päivi Salonen
    Administration Centre, Tampere University Hospital, Finland
    Int J Nurs Pract 17:396-410. 2011
    ..Women with breast cancer should be offered systematic support and education, which is tailored to women's individual needs...
  16. doi request reprint Adjuvant capecitabine in combination with docetaxel and cyclophosphamide plus epirubicin for breast cancer: an open-label, randomised controlled trial
    Heikki Joensuu
    Department of Oncology, Helsinki University Central Hospital, Helsinki, Finland
    Lancet Oncol 10:1145-51. 2009
    ..We aimed to investigate whether integration of capecitabine into such a regimen enhances outcome...
  17. ncbi request reprint Effectiveness of a 12-month exercise program on physical performance and quality of life of breast cancer survivors
    Tiina Saarto
    Department of Oncology, Helsinki University Central Hospital, Helsinki, Finland
    Anticancer Res 32:3875-84. 2012
    ..The study aimed at determining whether physical exercise training improves the quality of life (QoL) and physical fitness of breast cancer survivors...
  18. doi request reprint A phase-II study of combination of pegylated interferon alfa-2a and capecitabine in locally advanced or metastatic renal cell cancer
    Kaisa Leea Sunela
    Department of Oncology, Tampere University Hospital, P O Box 2000, 33521 Tampere, Finland
    Cancer Chemother Pharmacol 66:59-67. 2010
    ..Pegylated interferons might have more clinical activity and fewer side effects. This study evaluated the efficacy, tolerability, and safety of the combination of capecitabine and pegylated interferon alfa-2a...
  19. doi request reprint Early treatment response evaluation in patients with diffuse large B-cell lymphoma--a pilot study comparing volumetric MRI and PET/CT
    Xingchen Wu
    Department of Oncology, Tampere University Hospital, Tampere, Finland
    Mol Imaging Biol 13:785-92. 2011
    ....
  20. doi request reprint Glucose metabolism correlated with cellular proliferation in diffuse large B-cell lymphoma
    Xingchen Wu
    Department of Oncology, Tampere University Hospital, Tampere, Finland
    Leuk Lymphoma 53:400-5. 2012
    ..The results indicate that tumor proliferation potential might be predicted in vivo by FDG-PET/CT images. Thus, PET/CT is useful to guide biopsy by selecting sites with the BmSUV(max) when clinically appropriate...
  21. doi request reprint Correlations between Functional Imaging Markers Derived from PET/CT and Diffusion-Weighted MRI in Diffuse Large B-Cell Lymphoma and Follicular Lymphoma
    Xingchen Wu
    Department of Oncology, Tampere University Hospital, Tampere, Finland Medical Imaging Centre, Department of Radiology, Tampere University Hospital, Tampere, Finland Medical School, University of Tampere, Tampere, Finland
    PLoS ONE 9:e84999. 2014
    ..Further to compare the usefulness of these tumor markers in differentiating diagnosis of the two common types of Non-Hodgkin's lymphoma (NHL)...
  22. doi request reprint No correlation between glucose metabolism and apparent diffusion coefficient in diffuse large B-cell lymphoma: a PET/CT and DW-MRI study
    Xingchen Wu
    Department of Oncology, Tampere University Hospital, Tampere, Finland
    Eur J Radiol 79:e117-21. 2011
    ..Apparent diffusion coefficient (ADC) measured by DWI can provide information about tissue cellularity. The aim of the study was to evaluate the correlation between SUV and ADC in untreated diffuse large B-cell lymphoma (DLBCL)...
  23. doi request reprint Circulating levels of VEGFR-1 and VEGFR-2 in patients with metastatic melanoma treated with chemoimmunotherapy alone or combined with bevacizumab
    Pia P Vihinen
    Department of Oncology and Radiotherapy, University of Turku, Turku University Hospital, Finland
    Melanoma Res 21:431-7. 2011
    ..These markers might be useful in selecting patients responsive to antiangiogenic therapy...
  24. doi request reprint Comparison of different MRI sequences in lesion detection and early response evaluation of diffuse large B-cell lymphoma--a whole-body MRI and diffusion-weighted imaging study
    Xingchen Wu
    Department of Oncology, Tampere University Hospital, Tampere, Finland
    NMR Biomed 26:1186-94. 2013
    ..DWI with ADC mapping is an imaging modality with both diagnostic and prognostic value that could complement conventional MRI...
  25. doi request reprint Changes in quality of life in patients with breast cancer
    Päivi Salonen
    Administration Centre, Tampere University Hospital, Tampere, Finland
    J Clin Nurs 20:255-66. 2011
    ..To describe and compare changes in quality of life in two groups of patients with breast cancer and to identify factors predicting negative changes in quality of life within six months...
  26. ncbi request reprint Opening communication with cancer patients about sexuality-related issues
    Katja Hautamäki
    Heart Center, Tampere University Hospital, Tampere, Finland
    Cancer Nurs 30:399-404. 2007
    ..The most important reason for not raising the issue is lack of training. More intensive education on how to open discussions on sensitive areas such as sexuality is needed...
  27. ncbi request reprint A phase I study of an all-oral combination of vinorelbine/capecitabine in patients with metastatic breast cancer previously treated with anthracyclines and/or taxanes
    Pirkko Liisa Kellokumpu-Lehtinen
    Department of Oncology, Tampere University Hospital, Finland
    Clin Breast Cancer 7:401-5. 2006
    ..An all-oral regimen minimizes inconvenience for the patient and saves medical resources...
  28. doi request reprint Response analysis of non-hodgkin lymphoma using magnetic resonance imaging-based volumes
    Maija Rossi
    Regional Medical Imaging Centre, Department of Radiology, Tampere University Hospital, Tampere, Finland
    J Comput Assist Tomogr 33:466-74. 2009
    ..The aim of this study was to determine the volume of non-Hodgkin lymphomas (NHLs) using semiautomatic segmentation and to correlate these results with clinical findings, treatment, and prognosis in patients with B-cell-type NHL...
  29. doi request reprint Telephone intervention and quality of life in patients with breast cancer
    Päivi Salonen
    Department of Psychiatry, Tampere University Hospital, Tampere, Finland
    Cancer Nurs 32:177-90; quiz 191-2. 2009
    ..These results may help in discussing QOL issues and should be considered when planning and implementing interventions for patients with breast cancer...
  30. ncbi request reprint Effect of a vigorous aerobic regimen on physical performance in breast cancer patients - a randomized controlled pilot trial
    Riku Nikander
    Bone Research Group, UKK Institute for Health Promotion Research, Tampere, Finland
    Acta Oncol 46:181-6. 2007
    ..The present exercise regimen turned out to be feasible and effective among breast cancer patients in terms of physical performance. Large controlled trials are necessary to confirm these findings...
  31. ncbi request reprint Serum angiogenin levels predict treatment response in patients with stage IV melanoma
    Pia Vihinen
    Department of Oncology and Radiotherapy, Turku University Hospital, POB 52, Turku 20521, Finland
    Clin Exp Metastasis 24:567-74. 2007
    ..044). These data suggest that serum angiogenin levels might be of predictive value in the evaluation of treatment response for patients with stage IV melanoma...
  32. ncbi request reprint Renal cell carcinoma MIB-1, Bax and Bcl-2 expression and prognosis
    Jukka P Kallio
    Department of Urology, Pathology, University of Tampere, Tampere, Finland
    J Urol 172:2158-61. 2004
    ..We evaluated Bax and Bcl-2 levels in RCC, and their associations with prognosis, proliferation and traditional prognostic factors...
  33. ncbi request reprint Topoisomerase IIalpha gene amplification predicts favorable treatment response to tailored and dose-escalated anthracycline-based adjuvant chemotherapy in HER-2/neu-amplified breast cancer: Scandinavian Breast Group Trial 9401
    Minna Tanner
    Laboratory of Cancer Biology, Institute of Medical Technology, and Department of Oncology, Tampere University and Tampere University Hospital, Tampere, Finland
    J Clin Oncol 24:2428-36. 2006
    ..Their role in predicting the outcome of anthracycline-based adjuvant chemotherapy for breast cancer patients has remained controversial...
  34. ncbi request reprint [Support and control of psychological stress as experienced by cancer patient]
    Ulla Sisko Lehto-Järnstedt
    Tampereen yliopiston lääketieteen laitos, onkologia 33014 Tampereen yliopisto
    Duodecim 118:1457-65. 2002
  35. ncbi request reprint Attitudes to terminal patients' unorthodox therapy: Finnish doctors' responses to a case scenario
    Heikki Hinkka
    Kangasala Health Center, Herttualantie 28, 36200 Kangasala, Finland
    Support Care Cancer 12:132-6. 2004
    ....
  36. ncbi request reprint General practitioners' attitudes and ethical decisions in end-of-life care after a year of interactive Internet-based training
    Heikki Hinkka
    Kangasala Health Center, Finland
    J Cancer Educ 17:12-8. 2002
    ..A one-year Internet-mediated education project was arranged for general practitioners in Finland to provide postgraduate education in PC...
  37. ncbi request reprint Cancer-specific social support received by newly diagnosed cancer patients: validating the new Structural-Functional Social Support Scale (SFSS) measurement tool
    Ulla Sisko Lehto-Järnstedt
    Medical School, Oncology, University of Tampere, 33014, University of Tampere, Finland
    Support Care Cancer 12:326-37. 2004
    ..To investigate potentially health-enhancing domains of cancer patients' social relationships we evaluated various dimensions of social support as experienced in early cancer...
  38. ncbi request reprint Randomized trial of dacarbazine versus bleomycin, vincristine, lomustine and dacarbazine (BOLD) chemotherapy combined with natural or recombinant interferon-alpha in patients with advanced melanoma
    Meri Sisko Vuoristo
    Department of Oncology, University of Tampere and Tampere University Hospital, Tampere, Finland
    Melanoma Res 15:291-6. 2005
    ..Patients with soft tissue or lung metastases may achieve more complete responses with BOLD regimens...
  39. ncbi request reprint Genetic variation in platelet integrin alphabeta (GPIIb/IIIa) and the metastatic potential of renal cell carcinoma
    Jukka P Kallio
    Department of Urology, Tampere University Hosital, Tampere, Finland
    BJU Int 98:201-4. 2006
    ....
  40. ncbi request reprint Basoluminal carcinoma: a new biologically and prognostically distinct entity between basal and luminal breast cancer
    Mervi Laakso
    Department of Pathology, Seinajoki Central Hospital, Seinajoki, Finland
    Clin Cancer Res 12:4185-91. 2006
    ..Based on variable basal cytokeratin immunostaining patterns, we hypothesized that the "basal phenotype" tumor group may comprise more than one biological entity...
  41. ncbi request reprint Baseline psychosocial predictors of survival in localized melanoma
    Ulla Sisko Lehto
    University of Tampere, Medical School, and Department of Oncology, Tampere University Hospital, Finland
    J Psychosom Res 63:9-15. 2007
    ..We examined the simultaneous contribution of several theory-based psychosocial elements to survival time in melanoma...