Jouni Karppi

Summary

Affiliation: University of Kuopio
Country: Finland

Publications

  1. doi Lycopene, lutein and beta-carotene as determinants of LDL conjugated dienes in serum
    Jouni Karppi
    Research Institute of Public Health, School of Public Health and Clinical Nutrition, University of Kuopio, P O Box 1627, FI 70211 Kuopio, Finland
    Atherosclerosis 209:565-72. 2010
  2. doi Serum lycopene and the risk of cancer: the Kuopio Ischaemic Heart Disease Risk Factor (KIHD) study
    Jouni Karppi
    Research Institute of Public Health, School of Public Health and Clinical Nutrition, University of Kuopio, Kuopio, Finland
    Ann Epidemiol 19:512-8. 2009
  3. ncbi Suitability of Smopex-102 cation-exchange fiber for analytical purposes and drug monitoring
    J Karppi
    Laboratory Centre, Kuopio University Hospital, Finland
    Pharmazie 64:14-8. 2009
  4. doi Simultaneous measurement of retinol, alpha-tocopherol and six carotenoids in human plasma by using an isocratic reversed-phase HPLC method
    Jouni Karppi
    Research Institute of Public Health, School of Public Health and Clinical Nutrition, University of Kuopio, P O Box 1627, FIN 70211 Kuopio, Finland
    J Chromatogr B Analyt Technol Biomed Life Sci 867:226-32. 2008
  5. ncbi Effects of astaxanthin supplementation on lipid peroxidation
    Jouni Karppi
    Research Institute of Public Health, University of Kuopio, P O Box 1627, FI 70211 Kuopio, Finland
    Int J Vitam Nutr Res 77:3-11. 2007
  6. ncbi Isolation of drugs from biological fluids by using pH sensitive poly(acrylic acid) grafted poly(vinylidene fluoride) polymer membrane in vitro
    Jouni Karppi
    Laboratory Centre, Kuopio University Hospital, Kuopio, Finland
    Eur J Pharm Biopharm 67:562-8. 2007
  7. ncbi Adsorption of drugs onto a pH responsive poly(N,N-dimethyl aminoethyl methacrylate) grafted anion-exchange membrane in vitro
    Jouni Karppi
    Laboratory Centre, Kuopio University Hospital, P O Box 1777, FIN 70211 Kuopio, Finland
    Int J Pharm 338:7-14. 2007
  8. doi Low levels of plasma carotenoids are associated with an increased risk of atrial fibrillation
    Jouni Karppi
    Department of Medicine, Institute of Public Health and Clinical Nutrition, University of Eastern Finland, P O Box 1627, 70211 Kuopio, Finland
    Eur J Epidemiol 28:45-53. 2013
  9. doi Low serum lycopene and β-carotene increase risk of acute myocardial infarction in men
    Jouni Karppi
    Department of Medicine, University of Eastern Finland, Kuopio, Finland
    Eur J Public Health 22:835-40. 2012
  10. ncbi Serum β-carotene in relation to risk of prostate cancer: the Kuopio Ischaemic Heart Disease Risk Factor study
    Jouni Karppi
    Department of Medicine, Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland
    Nutr Cancer 64:361-7. 2012

Detail Information

Publications17

  1. doi Lycopene, lutein and beta-carotene as determinants of LDL conjugated dienes in serum
    Jouni Karppi
    Research Institute of Public Health, School of Public Health and Clinical Nutrition, University of Kuopio, P O Box 1627, FI 70211 Kuopio, Finland
    Atherosclerosis 209:565-72. 2010
    ..Results of the present study suggest that plasma lycopene, lutein and beta-carotene are the most powerful antioxidants for explaining the content of in vivo oxidatively modified LDL in serum...
  2. doi Serum lycopene and the risk of cancer: the Kuopio Ischaemic Heart Disease Risk Factor (KIHD) study
    Jouni Karppi
    Research Institute of Public Health, School of Public Health and Clinical Nutrition, University of Kuopio, Kuopio, Finland
    Ann Epidemiol 19:512-8. 2009
    ..Lycopene is thought to decrease the risk of cancers, although previous epidemiologic studies have produced inconsistent results. The aim of the present study was to evaluate the protective effect of lycopene against the risk of cancer...
  3. ncbi Suitability of Smopex-102 cation-exchange fiber for analytical purposes and drug monitoring
    J Karppi
    Laboratory Centre, Kuopio University Hospital, Finland
    Pharmazie 64:14-8. 2009
    ..g. serum) liquid solutions for subsequent monitoring and evaluation. However, the drug release solution and release time must be optimized more precisely in order to validate described sample preparation method for each basic drug...
  4. doi Simultaneous measurement of retinol, alpha-tocopherol and six carotenoids in human plasma by using an isocratic reversed-phase HPLC method
    Jouni Karppi
    Research Institute of Public Health, School of Public Health and Clinical Nutrition, University of Kuopio, P O Box 1627, FIN 70211 Kuopio, Finland
    J Chromatogr B Analyt Technol Biomed Life Sci 867:226-32. 2008
    ..The results of the comparison matched satisfactorily. The method is used routinely in our laboratory in a large population-based study...
  5. ncbi Effects of astaxanthin supplementation on lipid peroxidation
    Jouni Karppi
    Research Institute of Public Health, University of Kuopio, P O Box 1627, FI 70211 Kuopio, Finland
    Int J Vitam Nutr Res 77:3-11. 2007
    ..The present study suggests that intestinal absorption of astaxanthin delivered as capsules is adequate, and well tolerated. Supplementation with astaxanthin may decrease in vivo oxidation of fatty acids in healthy men...
  6. ncbi Isolation of drugs from biological fluids by using pH sensitive poly(acrylic acid) grafted poly(vinylidene fluoride) polymer membrane in vitro
    Jouni Karppi
    Laboratory Centre, Kuopio University Hospital, Kuopio, Finland
    Eur J Pharm Biopharm 67:562-8. 2007
    ..e. serum) for subsequent monitoring and evaluation...
  7. ncbi Adsorption of drugs onto a pH responsive poly(N,N-dimethyl aminoethyl methacrylate) grafted anion-exchange membrane in vitro
    Jouni Karppi
    Laboratory Centre, Kuopio University Hospital, P O Box 1777, FIN 70211 Kuopio, Finland
    Int J Pharm 338:7-14. 2007
    ....
  8. doi Low levels of plasma carotenoids are associated with an increased risk of atrial fibrillation
    Jouni Karppi
    Department of Medicine, Institute of Public Health and Clinical Nutrition, University of Eastern Finland, P O Box 1627, 70211 Kuopio, Finland
    Eur J Epidemiol 28:45-53. 2013
    ..Results of the present study suggest that low plasma concentrations of lutein and zeaxanthin were associated with an increased risk of AF in elderly population...
  9. doi Low serum lycopene and β-carotene increase risk of acute myocardial infarction in men
    Jouni Karppi
    Department of Medicine, University of Eastern Finland, Kuopio, Finland
    Eur J Public Health 22:835-40. 2012
    ..The role of carotenoids on the risk of AMI remains inconsistent. The aim of the present study was to examine if serum concentrations of major carotenoids are related to AMI in men...
  10. ncbi Serum β-carotene in relation to risk of prostate cancer: the Kuopio Ischaemic Heart Disease Risk Factor study
    Jouni Karppi
    Department of Medicine, Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland
    Nutr Cancer 64:361-7. 2012
    ..29, 95% CI: 1.12-4.66; P = 0.023). α-Tocopherol and retinol were not associated with prostate cancer. This prospective study suggests that high-serum β-carotene concentrations may increase the risk of prostate cancer in middle-aged men...
  11. pmc Serum carotenoids reduce progression of early atherosclerosis in the carotid artery wall among Eastern Finnish men
    Jouni Karppi
    University of Eastern Finland, Department of Medicine, Institute of Public Health and Clinical Nutrition, Kuopio, Finland
    PLoS ONE 8:e64107. 2013
    ..We assessed the association between atherosclerotic progression, measured by intima-media thickness of the common carotid artery wall, and serum levels of carotenoids...
  12. doi Serum β-carotene and the risk of sudden cardiac death in men: a population-based follow-up study
    Jouni Karppi
    University of Eastern Finland, Department of Medicine, Institute of Public Health and Clinical Nutrition, P O Box 1627, FI 70211 Kuopio, Finland
    Atherosclerosis 226:172-7. 2013
    ..To examine whether serum concentrations of carotenoids are related to the risk of sudden cardiac death (SCD) in middle-aged men...
  13. pmc Impaired fasting plasma glucose and type 2 diabetes are related to the risk of out-of-hospital sudden cardiac death and all-cause mortality
    Jari A Laukkanen
    Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland
    Diabetes Care 36:1166-71. 2013
    ..The aim of the study was to determine whether impaired fasting plasma glucose (FPG) and type 2 diabetes may be risk factors for sudden cardiac death (SCD)...
  14. doi Plasma lutein and zeaxanthin and the risk of age-related nuclear cataract among the elderly Finnish population
    Jouni Karppi
    Department of Medicine, Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland
    Br J Nutr 108:148-54. 2012
    ..In conclusion, we suggest that high plasma concentrations of lutein and zeaxanthin were associated with a decreased risk of age-related nuclear cataract in the elderly population...
  15. doi Serum lycopene decreases the risk of stroke in men: a population-based follow-up study
    Jouni Karppi
    Department of Medicine, Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland
    Neurology 79:1540-7. 2012
    ..The aim of the present study was to examine whether serum concentrations of major carotenoids, α-tocopherol and retinol, are related to any stroke and ischemic stroke in men...
  16. ncbi Comparison of HPLC method and commercial ELISA assay for asymmetric dimethylarginine (ADMA) determination in human serum
    Pirjo Valtonen
    Laboratory Centre, Kuopio University Hospital, P O Box 1777, FIN 70211 Kuopio, Finland
    J Chromatogr B Analyt Technol Biomed Life Sci 828:97-102. 2005
    ..ADMA concentration was stable after four freezing and thawing cycles. Overall, the HPLC method offered better sensitivity, selectivity and, very importantly, simultaneous determination of ADMA, SDMA, l-homoarginine and l-arginine...
  17. ncbi Adenovirus-mediated gene transfer of Lp-PLA2 reduces LDL degradation and foam cell formation in vitro
    Paivi Turunen
    A I Virtanen Institute for Molecular Sciences, University of Kuopio, FIN 70211 Kuopio, Finland
    J Lipid Res 45:1633-9. 2004
    ..It is concluded that increased Lp-PLA2 activity in LDL attenuates foam cell formation and decreases LDL oxidation and subsequent degradation in macrophages...