Research Topics
| Jouni KarppiSummaryAffiliation: University of Kuopio Country: Finland Publications
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Detail Information
Publications
Serum lycopene and the risk of cancer: the Kuopio Ischaemic Heart Disease Risk Factor (KIHD) studyJouni Karppi
Research Institute of Public Health, School of Public Health and Clinical Nutrition, University of Kuopio, Kuopio, Finland
Ann Epidemiol 19:512-8. 2009..Lycopene is thought to decrease the risk of cancers, although previous epidemiologic studies have produced inconsistent results. The aim of the present study was to evaluate the protective effect of lycopene against the risk of cancer...
Adsorption of drugs onto a pH responsive poly(N,N-dimethyl aminoethyl methacrylate) grafted anion-exchange membrane in vitroJouni Karppi
Laboratory Centre, Kuopio University Hospital, P O Box 1777, FIN 70211 Kuopio, Finland
Int J Pharm 338:7-14. 2007....
Isolation of drugs from biological fluids by using pH sensitive poly(acrylic acid) grafted poly(vinylidene fluoride) polymer membrane in vitroJouni Karppi
Laboratory Centre, Kuopio University Hospital, Kuopio, Finland
Eur J Pharm Biopharm 67:562-8. 2007..e. serum) for subsequent monitoring and evaluation...
Effects of astaxanthin supplementation on lipid peroxidationJouni Karppi
Research Institute of Public Health, University of Kuopio, P O Box 1627, FI 70211 Kuopio, Finland
Int J Vitam Nutr Res 77:3-11. 2007..The present study suggests that intestinal absorption of astaxanthin delivered as capsules is adequate, and well tolerated. Supplementation with astaxanthin may decrease in vivo oxidation of fatty acids in healthy men...
Simultaneous measurement of retinol, alpha-tocopherol and six carotenoids in human plasma by using an isocratic reversed-phase HPLC methodJouni Karppi
Research Institute of Public Health, School of Public Health and Clinical Nutrition, University of Kuopio, P O Box 1627, FIN 70211 Kuopio, Finland
J Chromatogr B Analyt Technol Biomed Life Sci 867:226-32. 2008..The results of the comparison matched satisfactorily. The method is used routinely in our laboratory in a large population-based study...
Suitability of Smopex-102 cation-exchange fiber for analytical purposes and drug monitoringJ Karppi
Laboratory Centre, Kuopio University Hospital, Finland
Pharmazie 64:14-8. 2009..g. serum) liquid solutions for subsequent monitoring and evaluation. However, the drug release solution and release time must be optimized more precisely in order to validate described sample preparation method for each basic drug...
Lycopene, lutein and beta-carotene as determinants of LDL conjugated dienes in serumJouni Karppi
Research Institute of Public Health, School of Public Health and Clinical Nutrition, University of Kuopio, P O Box 1627, FI 70211 Kuopio, Finland
Atherosclerosis 209:565-72. 2010..Results of the present study suggest that plasma lycopene, lutein and beta-carotene are the most powerful antioxidants for explaining the content of in vivo oxidatively modified LDL in serum...
Serum β-carotene in relation to risk of prostate cancer: the Kuopio Ischaemic Heart Disease Risk Factor studyJouni Karppi
Department of Medicine, Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland
Nutr Cancer 64:361-7. 2012..29, 95% CI: 1.12-4.66; P = 0.023). α-Tocopherol and retinol were not associated with prostate cancer. This prospective study suggests that high-serum β-carotene concentrations may increase the risk of prostate cancer in middle-aged men...
Serum β-carotene and the risk of sudden cardiac death in men: a population-based follow-up studyJouni Karppi
University of Eastern Finland, Department of Medicine, Institute of Public Health and Clinical Nutrition, P O Box 1627, FI 70211 Kuopio, Finland
Atherosclerosis 226:172-7. 2013..To examine whether serum concentrations of carotenoids are related to the risk of sudden cardiac death (SCD) in middle-aged men...
Plasma lutein and zeaxanthin and the risk of age-related nuclear cataract among the elderly Finnish populationJouni Karppi
Department of Medicine, Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland
Br J Nutr 108:148-54. 2012..In conclusion, we suggest that high plasma concentrations of lutein and zeaxanthin were associated with a decreased risk of age-related nuclear cataract in the elderly population...
Serum lycopene decreases the risk of stroke in men: a population-based follow-up studyJouni Karppi
Department of Medicine, Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland
Neurology 79:1540-7. 2012..The aim of the present study was to examine whether serum concentrations of major carotenoids, α-tocopherol and retinol, are related to any stroke and ischemic stroke in men...
Comparison of HPLC method and commercial ELISA assay for asymmetric dimethylarginine (ADMA) determination in human serumPirjo Valtonen
Laboratory Centre, Kuopio University Hospital, P O Box 1777, FIN 70211 Kuopio, Finland
J Chromatogr B Analyt Technol Biomed Life Sci 828:97-102. 2005..ADMA concentration was stable after four freezing and thawing cycles. Overall, the HPLC method offered better sensitivity, selectivity and, very importantly, simultaneous determination of ADMA, SDMA, l-homoarginine and l-arginine...
Low serum lycopene and β-carotene increase risk of acute myocardial infarction in menJouni Karppi
Department of Medicine, University of Eastern Finland, Kuopio, Finland
Eur J Public Health 22:835-40. 2012..The role of carotenoids on the risk of AMI remains inconsistent. The aim of the present study was to examine if serum concentrations of major carotenoids are related to AMI in men...
Adenovirus-mediated gene transfer of Lp-PLA2 reduces LDL degradation and foam cell formation in vitroPaivi Turunen
A I Virtanen Institute for Molecular Sciences, University of Kuopio, FIN 70211 Kuopio, Finland
J Lipid Res 45:1633-9. 2004..It is concluded that increased Lp-PLA2 activity in LDL attenuates foam cell formation and decreases LDL oxidation and subsequent degradation in macrophages...
