Research Topics
Genomes and GenesSpecies | O KampmanSummaryAffiliation: University of Tampere Country: Finland Publications
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Detail Information
Publications
Temperament profiles, major depression, and response to treatment with SSRIs in psychiatric outpatientsO Kampman
University of Tampere, Medical School, 33014 Tampere, Finland
Eur Psychiatry 27:245-9. 2012....
Association between 5-HT2A, TPH1 and GNB3 genotypes and response to typical neuroleptics: a serotonergic approachSami Anttila
University of Tampere, Medical School, University of Tampere, Finland
BMC Psychiatry 7:22. 2007..One major problem in the treatment is finding the right the drug for the right patients. However, pharmacogenetic results in psychiatry can seldom be replicated...
Indicators of medication compliance in first-episode psychosisOlli Kampman
Medical School, University of Tampere, FIN 33014 University of, Tampere, Finland
Psychiatry Res 110:39-48. 2002..During the acute phase of psychosis, insight and attitudes toward treatment are the sole determinants of the patients' prediction of compliance...
RGS4 genotype is not associated with antipsychotic medication response in schizophreniaO Kampman
Medical School, University of Tampere, Tampere, Finland
J Neural Transm 113:1563-8. 2006..The RGS4 (T > G, Rs 951436) genotype was not associated with incidence or age at onset in schizophrenia. Neither was the RGS4 genotype associated with medication response with two different subpopulations with schizophrenia...
Can onset and recovery in depression be predicted by temperament? A systematic review and meta-analysisOlli Kampman
University of Tampere, Medical School, Tampere, Finland
J Affect Disord 135:20-7. 2011....
Interaction of tumor necrosis alpha - G308A and epidermal growth factor gene polymorphisms in early-onset schizophreniaOlli Kampman
University of Tampere, Medical School, 33014 Tampere, Finland
Eur Arch Psychiatry Clin Neurosci 255:279-83. 2005..On the other hand, the role of cytokines in schizophrenia may involve genetic interactions predisposing early onset of illness...
Neuregulin genotype and medication response in Finnish patients with schizophreniaOlli Kampman
University of Tampere, Medical School, Tampere, Finland
Neuroreport 15:2517-20. 2004..The TT genotype was overrepresented in the non-responders group compared with the responders (p=0.013). Further studies are needed to ascertain the significance of neuregulin genotype in medication response to schizophrenia...
Apolipoprotein E polymorphism is associated with age of onset in schizophreniaOlli Kampman
Medical School, University of Tampere, 33014 Tampere, Finland
J Hum Genet 49:355-9. 2004..APOE epsilon 4/epsilon 4 genotype may be associated with early onset schizophrenia. APOE epsilon 3 allele may function protectively in later onset in this disease...
Four-year outcome in non-compliant schizophrenia patients treated with or without home-based ambulatory outpatient careO Kampman
University of Tampere, Medical School and Tampere Community Mental Health Care, 33014, Finland
Eur Psychiatry 18:1-5. 2003..The effectiveness of AOC on the mortality rates of schizophrenia patients needs further examination...
Dopamine receptor D2 -141C Insertion/Deletion polymorphism in a Finnish population with schizophreniaOlli Kampman
Department of Psychiatry, University of Tampere, Medical School, Tampere, FIN 33014, Finland
Psychiatry Res 121:89-92. 2003..The findings suggest that the frequency of the -141C Ins/Del polymorphism is lower in Northern Europe compared to other Caucasian and Japanese populations...
Lack of association between two polymorphisms of brain-derived neurotrophic factor and response to typical neurolepticsS Anttila
Department of Psychiatry, Tampere University Hospital, University of Tampere, Medical School, Tampere, Finland
J Neural Transm 112:885-90. 2005..Moreover, these polymorphisms of the BDNF gene are not associated with the risk of schizophrenia...
Interaction between NOTCH4 and catechol-O-methyltransferase genotypes in schizophrenia patients with poor response to typical neurolepticsSami Anttila
University of Tampere, Medical School, 33014 University of Tampere, Finland
Pharmacogenetics 14:303-7. 2004..Our sample consisted of 94 Finnish patients with DSM-IV schizophrenia and 98 controls...
RGS4 polymorphism and response to electroconvulsive therapy in major depressive disorderKaija Huuhka
University of Tampere, Medical School, Department of Psychiatry, Tampere University Hospital, Tampere, Finland
Neurosci Lett 437:25-8. 2008..According to the present data, the impact of RGS4 genotype is not decisive in major depressive disorder. The results provide preliminary data on the impact of RGS4 polymorphism in treatment response in ECT...
Association of EGF polymorphism with schizophrenia in Finnish menSami Anttila
University of Tampere, Medical School, Finland
Neuroreport 15:1215-8. 2004..594 (95% CI 1.347-9.591), p = 0.008). The G allele was also associated with a later age at onset in male patients with schizophrenia. However, no association was found between treatment response and EGF polymorphism...
Association between the C957T polymorphism of the dopamine D2 receptor gene and schizophreniaKari Hänninen
South Karelia Central Hospital, Department of Psychiatry, Lappeenranta, Finland
Neurosci Lett 407:195-8. 2006..05). Our results are in agreement with an earlier association study suggesting that the C957T C-allele plays a role in the genetic vulnerability for schizophrenia and support the involvement of the DRD2 gene in schizophrenia pathogenesis...
NOTCH4 gene promoter polymorphism is associated with the age of onset in schizophreniaSami Anttila
University of Tampere, Medical School, Tampereen yliopisto, Finland
Psychiatr Genet 13:61-4. 2003..We conducted a prospective case-control study to explore the impact of NOTCH4 T-25C polymorphism on the factors associated with schizophrenia...
Vascular endothelial growth factor (VEGF) polymorphism is associated with treatment resistant depressionMerja Viikki
University of Tampere, Medical School, Tampere, Finland
Neurosci Lett 477:105-8. 2010..The finding suggests an association between VEGF 2578 C/A polymorphism and treatment resistant depression which is reported for the first time. Further studies with larger samples will be required to confirm the results...
Catechol-O-methyltransferase val108/158met genotype, major depressive disorder and response to selective serotonin reuptake inhibitors in major depressive disorderAri Illi
University of Tampere, Medical School, Tampere, Finland
Psychiatry Res 176:85-7. 2010....
TPH1 218A/C polymorphism is associated with major depressive disorder and its treatment responseMerja Viikki
University of Tampere, Medical School, Tampere, Finland Tampere Mental Health Centre, Tampere, Finland
Neurosci Lett 468:80-4. 2010..Further studies with larger samples will be required to confirm the results...
5-HTR1A, 5-HTR2A, 5-HTR6, TPH1 and TPH2 polymorphisms and major depressionAri Illi
University of Tampere, Medical School, Tampere, Finland
Neuroreport 20:1125-8. 2009..None of the seven single nucleotide polymorphisms was associated with major depressive disorder or with treatment response in our study population of Finnish individuals...
ACE polymorphism and response to electroconvulsive therapy in major depressionJuhani Akseli Stewart
University of Tampere, Medical School, 33014 Tampere, Finland
Neurosci Lett 458:122-5. 2009..Distributions of these genotypes or alleles did not differ between patients and controls. The studied ACE genotype was not associated with ECT results but may be associated with age of onset of the illness in patients with MDD...
Catechol-O-methyltransferase val108/158met genotype and response to antipsychotic medication in schizophreniaAri Illi
University of Tampere, Medical School, and Tampere University Hospital, Department of Psychiatry, Finland
Hum Psychopharmacol 22:211-5. 2007..We could not demonstrate any clearly significant effect of this particular COMT genotype in relation to the daily maintenance dosages of antipsychotics in patients with schizophrenia...
Interaction between angiotensin-converting enzyme and catechol-O-methyltransferase genotypes in schizophrenics with poor response to conventional neurolepticsAri Illi
Tampere University Hospital, Department of Psychiatry, Tampere, Finland
Eur Neuropsychopharmacol 13:147-51. 2003..ACE genotype alone did not differ between any groups. This finding may suggest a possible interaction with low activity COMT and high activity ACE genotype in association with poor response to conventional neuroleptics...
Catechol-O-methyltransferase and monoamine oxidase A genotypes and drug response to conventional neuroleptics in schizophreniaAri Illi
Department of Psychiatry, Tampere University Hospital, Tampere, Finland
J Clin Psychopharmacol 23:429-34. 2003..The role of monoamine oxidase A genotype seems to be additive in this respect...
Patient characteristics and diagnostic discrepancy in first-episode psychosisOlli Kampman
University of Tampere, Medical School, Finland
Compr Psychiatry 45:213-8. 2004..The results confirm some of the findings in the few previous studies. The diagnosis of schizophrenia is likely to be delayed and there is a need for further education with clinicians in recognizing the symptoms of schizophrenia...
[Is antipsychotic drug therapy predictable?]Esa Leinonen
Tampereen yliopiston lääketieteen laitos
Duodecim 121:45-52. 2005
