E Kalso

Summary

Affiliation: University of Helsinki
Country: Finland

Publications

  1. pmc Development of a screening instrument for risk factors of persistent pain after breast cancer surgery
    R Sipilä
    Department of Anaesthesia and Intensive Care, Pain Clinic, Helsinki University Central Hospital, PO Box 140, 00029 HUS, Helsinki, Finland
    Br J Cancer 107:1459-66. 2012
  2. ncbi request reprint Epidural and subcutaneous morphine in the management of cancer pain: a double-blind cross-over study
    E Kalso
    Department of Anaesthesia, Helsinki University Central Hospital, Finland
    Pain 67:443-9. 1996
  3. ncbi request reprint No pain, no gain: clinical excellence and scientific rigour--lessons learned from IA morphine
    Eija Kalso
    Pain Clinic, Department of Anaesthesia and Intensive Care, Helsinki University Hospital, P O Box 340, Helsinki, FIN 00029 HUS, Finland
    Pain 98:269-75. 2002
  4. ncbi request reprint Five easy pieces on evidence based medicine (5). Trading benefit against harm--pain relief vs. adverse effects
    Eija Kalso
    Pain Clinic, Department of Anaesthesia and Intensive Care Medicine, Helsinki University Hospital, Helsinki, Finland
    Eur J Pain 6:409-12. 2002
  5. ncbi request reprint Opioids in chronic non-cancer pain: systematic review of efficacy and safety
    Eija Kalso
    Pain Clinic, Department of Anaesthesia and Intensive Care Medicine, Helsinki University Central Hospital, P O Box 340, FIN 00029 HUS, Finland
    Pain 112:372-80. 2004
  6. ncbi request reprint Chronic post-sternotomy pain
    E Kalso
    Department of Anaesthesia and Intensive Care Medicine, Helsinki University Central Hospital, Helsinki, Finland
    Acta Anaesthesiol Scand 45:935-9. 2001
  7. ncbi request reprint Improving opioid effectiveness: from ideas to evidence
    Eija Kalso
    Department of Anaesthesia and Intensive Care Medicine, Pain Clinic, Helsinki University Central Hospital, P O Box 340, FIN 00029 HUS, Finland
    Eur J Pain 9:131-5. 2005
  8. ncbi request reprint Sodium channel blockers in neuropathic pain
    Eija Kalso
    University of Helsinki, Institute of Clinical Medicine, Pain Clinic, Department of Anaesthesia and Intensive Care Medicine, Helsinki University Central Hospital, P O Box 340, FIN 00029 HUS, Finland
    Curr Pharm Des 11:3005-11. 2005
  9. ncbi request reprint Endogenous noradrenergic tone controls symptoms of allodynia in the spinal nerve ligation model of neuropathic pain
    M Xu
    Department of Pharmacology and Toxicology, Institute of Biomedicine, University of Helsinki, Finland
    Eur J Pharmacol 366:41-5. 1999
  10. ncbi request reprint Effects of (1DMe)NPYF, a synthetic neuropeptide FF analogue, in different pain models
    M Xu
    Department of Pharmacology and Toxicology, Institute of Biomedicine, University of Helsinki, Finland
    Peptides 20:1071-7. 1999

Collaborators

Detail Information

Publications66

  1. pmc Development of a screening instrument for risk factors of persistent pain after breast cancer surgery
    R Sipilä
    Department of Anaesthesia and Intensive Care, Pain Clinic, Helsinki University Central Hospital, PO Box 140, 00029 HUS, Helsinki, Finland
    Br J Cancer 107:1459-66. 2012
    ....
  2. ncbi request reprint Epidural and subcutaneous morphine in the management of cancer pain: a double-blind cross-over study
    E Kalso
    Department of Anaesthesia, Helsinki University Central Hospital, Finland
    Pain 67:443-9. 1996
    ..Both treatments provided better pain relief with less adverse effects compared with the prestudy oral morphine treatment...
  3. ncbi request reprint No pain, no gain: clinical excellence and scientific rigour--lessons learned from IA morphine
    Eija Kalso
    Pain Clinic, Department of Anaesthesia and Intensive Care, Helsinki University Hospital, P O Box 340, Helsinki, FIN 00029 HUS, Finland
    Pain 98:269-75. 2002
    ..A minimum of 30% of the maximum possible pain intensity is needed for an analgesic effect to be detected in a study...
  4. ncbi request reprint Five easy pieces on evidence based medicine (5). Trading benefit against harm--pain relief vs. adverse effects
    Eija Kalso
    Pain Clinic, Department of Anaesthesia and Intensive Care Medicine, Helsinki University Hospital, Helsinki, Finland
    Eur J Pain 6:409-12. 2002
  5. ncbi request reprint Opioids in chronic non-cancer pain: systematic review of efficacy and safety
    Eija Kalso
    Pain Clinic, Department of Anaesthesia and Intensive Care Medicine, Helsinki University Central Hospital, P O Box 340, FIN 00029 HUS, Finland
    Pain 112:372-80. 2004
    ..The small number of selected patients and the short follow-ups do not allow conclusions concerning problems such as tolerance and addiction...
  6. ncbi request reprint Chronic post-sternotomy pain
    E Kalso
    Department of Anaesthesia and Intensive Care Medicine, Helsinki University Central Hospital, Helsinki, Finland
    Acta Anaesthesiol Scand 45:935-9. 2001
    ..The aim of this paper was to study the incidence and possible risk factors of chronic pain following sternotomy operations performed for coronary bypass grafting or thymectomy...
  7. ncbi request reprint Improving opioid effectiveness: from ideas to evidence
    Eija Kalso
    Department of Anaesthesia and Intensive Care Medicine, Pain Clinic, Helsinki University Central Hospital, P O Box 340, FIN 00029 HUS, Finland
    Eur J Pain 9:131-5. 2005
    ..The theoretical background and the clinical evidence of these combinations will be discussed...
  8. ncbi request reprint Sodium channel blockers in neuropathic pain
    Eija Kalso
    University of Helsinki, Institute of Clinical Medicine, Pain Clinic, Department of Anaesthesia and Intensive Care Medicine, Helsinki University Central Hospital, P O Box 340, FIN 00029 HUS, Finland
    Curr Pharm Des 11:3005-11. 2005
    ..An oral local anesthetic type sodium channel blocker, mexiletine is an antiarrhythmic agent that is effective in neuropathic pain. However, effective doses may be difficult to achieve because of adverse effects...
  9. ncbi request reprint Endogenous noradrenergic tone controls symptoms of allodynia in the spinal nerve ligation model of neuropathic pain
    M Xu
    Department of Pharmacology and Toxicology, Institute of Biomedicine, University of Helsinki, Finland
    Eur J Pharmacol 366:41-5. 1999
    ..t. or 1 mg/kg s.c.) had no effect on the neuropathic symptoms. These results indicate that mechanical and cold allodynia are under endogenous noradrenergic rather than opioidergic control in this model of neuropathic pain...
  10. ncbi request reprint Effects of (1DMe)NPYF, a synthetic neuropeptide FF analogue, in different pain models
    M Xu
    Department of Pharmacology and Toxicology, Institute of Biomedicine, University of Helsinki, Finland
    Peptides 20:1071-7. 1999
    ..In the neuropathic pain model, the lowest dose tested (0.5 nmol) showed antiallodynic effects against cold allodynia. The results suggest a potential role for (1DMe)NPYF in the treatment of pain including neuropathic pain...
  11. doi request reprint Itraconazole, a potent inhibitor of P-glycoprotein, moderately increases plasma concentrations of oral morphine
    T Heiskanen
    Pain Clinic, Department of Anaesthesiology and Intensive Care Medicine, Helsinki University Central Hospital, Helsinki, Finland
    Acta Anaesthesiol Scand 52:1319-26. 2008
    ..The aim of this study was to evaluate whether itraconazole, which is a potent inhibitor of P-glycoprotein and CYP3A4, would change the pharmacokinetics or the pharmacodynamics of oral morphine...
  12. ncbi request reprint Treatment-related factors predisposing to chronic pain in patients with breast cancer--a multivariate approach
    T Tasmuth
    Department of Anaesthesia, Helsinki University Central Hospital, Finland
    Acta Oncol 36:625-30. 1997
    ..The most important factors included in the models of chronic pain were: intensity of the acute postoperative pain, the type of operation, involvement of regional lymph nodes and radiotherapy...
  13. ncbi request reprint The effects of the alpha2-adrenergic agonist, dexmedetomidine, in the spinal nerve ligation model of neuropathic pain in rats
    V K Kontinen
    Department of Pharmacology and Toxicology, Institute of Biomedicine, University of Helsinki, Finland
    Anesth Analg 86:355-60. 1998
    ..At tolerable doses, systemic dexmedetomidine neither prevented nor attenuated neuropathic pain behavior...
  14. ncbi request reprint Analgesic effects of dextromethorphan and morphine in patients with chronic pain
    Tarja Heiskanen
    Pain Clinic, Helsinki University Hospital, P O Box 340, 00029 HUS, Helsinki, Finland
    Pain 96:261-7. 2002
    ..There were no significant differences in either the incidence or severity of adverse effects. In conclusion, oral dextromethorphan 100 mg had no effect on pain relief by intravenous morphine 15 mg in patients with chronic pain...
  15. ncbi request reprint Effects of radolmidine, a novel alpha2 -adrenergic agonist compared with dexmedetomidine in different pain models in the rat
    M Xu
    Department of Pharmacology and Toxicology, Institute of Biomedicine, University of Helsinki, Helsinki University Hospital, Finland
    Anesthesiology 93:473-81. 2000
    ..This study determined the antinociceptive and sedative effects of radolmidine in different models of acute and chronic pain. Dexmedetomidine and saline served as controls...
  16. ncbi request reprint Post-thoracotomy pain after thoracic epidural analgesia: a prospective follow-up study
    E Tiippana
    Department of Anaesthesia and Intensive Care Medicine, Helsinki University Central Hospital, Helsinki, Finland
    Acta Anaesthesiol Scand 47:433-8. 2003
    ..We wanted to find out if active use of TEA, combined with extended pain management at home, reduces the incidence of chronic post-thoracotomy pain...
  17. ncbi request reprint Peri-operative ketamine for acute post-operative pain: a quantitative and qualitative systematic review (Cochrane review)
    R F Bell
    Pain Clinic, Department of Anaesthesia and Intensive Care, Haukeland University Hospital and Department of Surgical Sciences, University of Bergen, Norway
    Acta Anaesthesiol Scand 49:1405-28. 2005
    ..The objective of this systematic review was to evaluate the effectiveness and tolerability of ketamine administered peri-operatively in the treatment of acute post-operative pain in adults...
  18. pmc Pain and other symptoms during the first year after radical and conservative surgery for breast cancer
    T Tasmuth
    Department of Anaesthesia, Helsinki University Central Hospital, Finland
    Br J Cancer 74:2024-31. 1996
    ..Both the anxiety and depression scores were highest before surgery, decreasing with time, and were significantly correlated with preoperative stressful events...
  19. pmc Inhibitors of catechol-O-methyltransferase sensitize mice to pain
    O Kambur
    Primary laboratory of origin Division of Pharmacology and Toxicology, Faculty of Pharmacy, University of Helsinki, Helsinki, Finland
    Br J Pharmacol 161:1553-65. 2010
    ..Here, we have assessed the effects of acute and repeated administrations of COMT inhibitors on mechanical, thermal and carrageenan-induced nociception in male mice...
  20. ncbi request reprint Effects of blocking CYP2D6 on the pharmacokinetics and pharmacodynamics of oxycodone
    T Heiskanen
    Department of Anaesthesia, Helsinki University Central Hospital, Finland
    Clin Pharmacol Ther 64:603-11. 1998
    ..The aim of this study was to evaluate the role of oxymorphone in mediating the opioid effects of oxycodone by means of blocking CYP2D6 with quinidine...
  21. doi request reprint Widespread unilateral pain associated with herpes simplex virus infections
    Katariina Kallio-Laine
    Pain Clinic, Department of Anesthesiology and Intensive Care Medicine, Helsinki University Central Hospital, HUS, Helsinki, Finland
    J Pain 9:658-65. 2008
    ....
  22. doi request reprint Effect of paracetamol and coxib with or without dexamethasone after laparoscopic cholecystectomy
    E Tiippana
    Department of Anaesthesiology, Intensive Care Medicine, Emergency Medicine and Pain Medicine, Helsinki University Hospital, Helsinki, Finland
    Acta Anaesthesiol Scand 52:673-80. 2008
    ..Effective post-operative pain control is necessary in LCC performed as day-case surgery. We studied the efficacy of paracetamol or valdecoxib with or without dexamethasone after LCC...
  23. ncbi request reprint Disodium clodronate in the treatment of diffuse sclerosing osteomyelitis (DSO) of the mandible
    M Montonen
    Department of Oral and Maxillofacial Surgery, Helsinki University Central Hospital, Finland
    Int J Oral Maxillofac Surg 30:313-7. 2001
    ..However, 6 months after treatment there was a statistically significant difference in pain intensity between the groups, with the disodium clodronate group experiencing significantly less pain...
  24. doi request reprint Clustering of symptoms associated with fibromyalgia in a Finnish Twin Cohort
    Ritva Markkula
    Helsinki University Central Hospital, Pain Clinic, Department of Anaesthesiology and Intensive Care Medicine, 00029 HUS Helsinki, Finland
    Eur J Pain 13:744-50. 2009
    ..The symptoms known to be associated with fibromyalgia seem to have a strong genetic background...
  25. doi request reprint Stress-induced analgesia and morphine responses are changed in catechol-O-methyltransferase-deficient male mice
    Oleg Kambur
    Department of Pharmacology, Institute of Biomedicine, University of Helsinki, Helsinki, Finland
    Basic Clin Pharmacol Toxicol 103:367-73. 2008
    ..COMT activity seems to take part in the modulation of nociception not only in the brain, as suggested earlier, but also at the spinal/peripheral level...
  26. ncbi request reprint Morphine, oxycodone, methadone and its enantiomers in different models of nociception in the rat
    Kim Lemberg
    Department of Pharmacology, Institute of Biomedicine, University of Helsinki, Finland
    Anesth Analg 102:1768-74. 2006
    ..Opioids seem to have different profiles in different pain models. l-methadone should be studied for neuropathic pain in humans...
  27. doi request reprint HLA-DRB1*01 allele and low plasma immunoglobulin G1 concentration may predispose to herpes-associated recurrent lymphocytic meningitis
    Katariina Kallio-Laine
    Pain Clinic, Department of Anaesthesiology and Intensive Care Medicine, Helsinki University Central Hospital, Helsinki, Finland
    Hum Immunol 71:179-81. 2010
    ..05). HLA-DRB1*01 (p = 0.009) and -B*27 (p = 0.050) were more common among patients than controls. We conclude that HLA-DRB1*01 and -B*27 alleles and low plasma IgG1 levels may be significant risk factors for RLM...
  28. pmc Recurrent lymphocytic meningitis positive for herpes simplex virus type 2
    Katariina Kallio-Laine
    Helsinki University Central Hospital, Helsinki, Finland
    Emerg Infect Dis 15:1119-22. 2009
    ..2/100,000 population in Finland during 1996-2006, higher than previous estimates. PCR was most sensitive in detecting HSV-2 DNA from cerebrospinal fluid if the sample was taken 2-5 days after symptom onset...
  29. ncbi request reprint Medical undergraduate students' beliefs and attitudes toward pain: how do they mature?
    Leila Niemi-Murola
    Department of Anaesthesiology and Intensive Care Medicine, Helsinki University Central Hospital, Finland
    Eur J Pain 11:700-6. 2007
    ..Attitudes towards treating the pain of cancer patients and elderly patients are positive. Attention should be paid to helping students to cope with their emotions and to reducing their anxiety about meeting patients with chronic pain...
  30. ncbi request reprint Placebo and opioid analgesia-- imaging a shared neuronal network
    Predrag Petrovic
    Cognitive Neurophysiology Research Group, Department of Clinical Neuroscience, Karolinska Institute, Stockholm 171 76, Sweden, Pain Clinic, Department of Anaesthesia and Intensive Care Medicine, Helsinki University Hospital, Finland
    Science 295:1737-40. 2002
    ..These findings indicate a related neural mechanism in placebo and opioid analgesia...
  31. ncbi request reprint Do strong opioids have a role in the early management of back pain? Recommendations from a European expert panel
    Eija Kalso
    Pain Clinic, Helsinki University Central Hospital, Helsinki, Finland
    Curr Med Res Opin 21:1819-28. 2005
    ..Given the prevalence of CLBP, and the complex nature of this multifactorial condition, it was felt that specific, evidence-based recommendations, with a focus on primary-care treatment, would be helpful...
  32. ncbi request reprint A systematic review of trial methodology, using the placebo groups of randomized controlled trials in paediatric postoperative pain
    Katri Hamunen
    Pain Clinic, Department of Anaesthesia and Intensive Care Medicine, Helsinki University Central Hospital, P O Box 140, FIN 00029 HUS, Finland
    Pain 116:146-58. 2005
    ..In conclusion, analysis of the methodology showed several aspects of trial design that can be improved in future studies. Placebo control groups can be used in paediatric analgesic studies to demonstrate internal sensitivity...
  33. doi request reprint Effect of pain on autonomic nervous system indices derived from photoplethysmography in healthy volunteers
    K Hamunen
    Pain Clinic, Department of Anaesthesia and Intensive Care, Helsinki University Central Hospital, PO Box 140, Helsinki FIN 00029 HUS, Finland
    Br J Anaesth 108:838-44. 2012
    ..The aim of our study was to correlate the intensity of experimental pain to changes in physiological variables reflecting the autonomic nervous system response to pain...
  34. doi request reprint Transdermal fentanyl in cachectic cancer patients
    Tarja Heiskanen
    Pain Clinic, Department of Anesthesiology and Intensive Care Medicine, Helsinki University Central Hospital, P O Box 140, 00029 HUS Helsinki, Finland
    Pain 144:218-22. 2009
    ..Absorption of transdermal fentanyl is impaired in cachectic patients compared with that of normal weight cancer pain patients...
  35. pmc Predicting long-term response to strong opioids in patients with low back pain: findings from a randomized, controlled trial of transdermal fentanyl and morphine
    Eija Kalso
    Pain Clinic, Helsinki University Central Hospital, Helsinki, Finland
    BMC Med 5:39. 2007
    ..We assessed data from a large-scale randomized comparison of transdermal fentanyl (TDF) and sustained-release oral morphine (slow-release morphine; SRM) to determine characteristics of treatment responders...
  36. doi request reprint Pain intensity influences the relationship between anger management style and depression
    Ann Mari Estlander
    Helsinki University Central Hospital, Pain Clinic, Mannerheimvagen 110 A 4, 00250 Helsinki, Finland
    Pain 140:387-92. 2008
    ..However, analysing separately the two subscales of the BDI, negative view and physical function, significant positive relationships between pain intensity and both subscales appeared...
  37. ncbi request reprint Venlafaxine in neuropathic pain following treatment of breast cancer
    Tiina Tasmuth
    Pain Clinic, Department of Anaesthesia and Intensive Care Medicine, Helsinki University Central Hospital, FIN 00029 HUS, Helsinki, Finland
    Eur J Pain 6:17-24. 2002
    ..The two poor responders had low venlafaxine concentrations whereas the two slow hydroxylizers had high venlafaxine concentrations and excellent pain relief. Thus, higher doses could be used in order to improve pain relief...
  38. ncbi request reprint Recommendations for using opioids in chronic non-cancer pain
    Eija Kalso
    Helsinki University Central Hospital, Finland
    Eur J Pain 7:381-6. 2003
    ..6. Treatment should be monitored. 7. A contract setting out the patient's rights and responsibilities may help to emphasize the importance of patient involvement. 8. Opioid treatment should not be considered a lifelong treatment...
  39. ncbi request reprint Role of the delta-opioid receptor in (1DMe)NPYF mediated antinociception
    M Xu
    Department of Pharmacology and Toxicology, Institute of Biomedicine, University of Helsinki, Finland
    Peptides 22:33-8. 2001
    ..01-0.001). These data suggest that activation of spinal delta-opioid receptors plays an important role in mediating the spinal antinociceptive effects of (1DMe)NPYF...
  40. ncbi request reprint The outcome of pain related undergraduate teaching in Finnish medical faculties
    R Poyhia
    Department of Anaesthesia and Intensive Care Medicine, Helsinki University Central Hospital, P O Box 340, FIN 00029 HUS Helsinki, Finland
    Pain 115:234-7. 2005
    ..The clinical problems were excellently solved. In conclusion, the IASP curriculum is well covered in the present programmes in the Finnish medical faculties. However, the quality and the methods of teaching still need improvement...
  41. ncbi request reprint Oxycodone
    Eija Kalso
    University of Helsinki, and Department of Anesthesia and Intensive Care Medicine, Helsinki University Central Hospital, Helsinki, Finland
    J Pain Symptom Manage 29:S47-56. 2005
    ..Oxycodone closely resembles morphine but it has some distinct differences, particularly in its pharmacokinetic profile. Being an old drug, the basic pharmacology of oxycodone has been a neglected field of research...
  42. ncbi request reprint Five easy pieces on evidence-based medicine (4)
    Eija Kalso
    Pain Clinic, Department of Anaesthesia and Intensive Care Medicine, Helsinki University Hospital, Helsinki, Finland
    Eur J Pain 6:89-93. 2002
  43. ncbi request reprint Amitriptyline in the prevention of chemotherapy-induced neuropathic symptoms
    Anna Liisa Kautio
    Department of Oncology, Helsinki University Central Hospital, 00029 HUS, Finland
    Anticancer Res 29:2601-6. 2009
    ..This double-blind, randomized placebo-controlled trial assessed the efficacy of amitriptyline to prevent chemotherapy-induced neuropathic symptoms...
  44. doi request reprint Trends in opioid consumption in the Nordic countries 2002-2006
    Katri Hamunen
    Pain Clinic, Department of Anaesthesiology and Intensive Care Medicine, Helsinki University Central Hospital, Meilahti Hospital, Helsinki, HUS, Finland
    Eur J Pain 13:954-62. 2009
    ..The purpose of the study was to examine the trends in opioid consumption in the five Nordic countries between 2002 and 2006 and to explore possible explanations for changes in the quality and quantity of opioids consumed...
  45. ncbi request reprint Amitriptyline in the treatment of chemotherapy-induced neuropathic symptoms
    Anna Liisa Kautio
    Department of Oncology, Helsinki University Central Hospital, Helsinki, Finland
    J Pain Symptom Manage 35:31-9. 2008
    ..No statistical significance was reached, probably due to the small number of patients and too low dose of amitriptyline. Amitriptyline was well tolerated...
  46. ncbi request reprint What do different databases tell about the use of opioids in seven European countries in 2002?
    Katri Hamunen
    Pain Clinic, Department of Anaesthesiology and Intensive Care Medicine, Helsinki University Central Hospital, P O Box 140, FIN 00029 HUS, Finland
    Eur J Pain 12:705-15. 2008
    ..The objective of this paper was to analyse opioid consumption in a number European countries using different sources of data...
  47. ncbi request reprint Do surgical patients benefit from perioperative gabapentin/pregabalin? A systematic review of efficacy and safety
    Elina M Tiippana
    Pain Clinic, Department of Anaesthesia and Intensive Care Medicine, Helsinki University Central Hospital, Helsinki, Finland
    Anesth Analg 104:1545-56, table of contents. 2007
    ..These properties may also be beneficial in acute postoperative pain. In this study we evaluated randomized, controlled trials examining the analgesic efficacy, adverse effects, and clinical value of gabapentinoids in postoperative pain...
  48. ncbi request reprint Radiofrequency denervation for neck and back pain: a systematic review within the framework of the cochrane collaboration back review group
    Leena Niemistö
    ORTON Orthopaedic Hospital, Invalid Foundation, Helsinki, Finland
    Spine (Phila Pa 1976) 28:1877-88. 2003
    ..Systematic review...
  49. ncbi request reprint Acute opioid effects on human brain as revealed by functional magnetic resonance imaging
    Mika Leppä
    Department of Anesthesia and Intensive Care Medicine, Helsinki University Central Hospital, P O Box 340, FIN 00029 HUS, Finland
    Neuroimage 31:661-9. 2006
    ..These areas belong to a circuitry that modulates the affective experience of sensory stimuli...
  50. ncbi request reprint Venlafaxine in the treatment of atypical facial pain: a randomized controlled trial
    Heli Forssell
    Department of Oral Diseases Pain Clinic, Turku University Central Hospital Turku, Finland
    J Orofac Pain 18:131-7. 2004
    ..To study in a randomized placebo-controlled design the efficacy of the antidepressant venlafaxine, a serotonin and a weak noradrenaline reuptake inhibitor, in the treatment of atypical facial pain (AFP)...
  51. ncbi request reprint [Opioids in the treatment of pain--efficient weapon in the expert's hand]
    Eija Kalso
    HYKS, anestesiologia ja tehohoito, kipuklinikka PL 340, 00029 HUS
    Duodecim 120:195-6. 2004
  52. ncbi request reprint Ketamine as adjuvant to opioids for cancer pain. A qualitative systematic review
    Rae F Bell
    Pain Clinic, Department of Anesthesia and Intensive Care, Haukeland University Hospital, 5021 Bergen, Norway
    J Pain Symptom Manage 26:867-75. 2003
    ..High quality, randomized, controlled trials with larger numbers of patients and standardized, clinically relevant routes of administration of ketamine are needed...
  53. ncbi request reprint Of mice and men: what can we predict from the effects of morphine in a mouse model of bone cancer?
    Vesa K Kontinen
    Pain 132:5-7. 2007
  54. ncbi request reprint Is intranasal ketamine an appropriate treatment for chronic non-cancer breakthrough pain?
    Rae F Bell
    Pain 108:1-2. 2004
  55. ncbi request reprint Application of principles of evidence-based medicine to occlusal treatment for temporomandibular disorders: are there lessons to be learned?
    Heli Forssell
    Department of Oral Diseases Pain Clinic, Turku University Central Hospital, Turku, Finland
    J Orofac Pain 18:9-22; discussion 23-32. 2004
    ..None of the occlusal adjustment studies provided evidence supporting the use of this treatment method. The clinical implications of the findings and future perspectives are discussed...
  56. pmc Opioids for persistent non-cancer pain
    Eija Kalso
    BMJ 330:156-7. 2005
  57. ncbi request reprint Successful and unsuccessful outcomes with long-term opioid therapy: a survey of physicians' opinions
    Mina Nishimori
    The MGH Pain Center, Department of Anesthesia and Critical Care, Massachusetts General Hospital and Harvard Medical School, Boston Massachusetts 02114, USA
    J Palliat Med 9:50-6. 2006
    ..The attitudes, beliefs, and experience of physicians will influence how they view the use of opioids for chronic nonterminal pain...
  58. ncbi request reprint How different is oxycodone from morphine?
    Eija Kalso
    Pain 132:227-8. 2007
  59. ncbi request reprint [Only placebo?]
    Eija Kalso
    Duodecim 118:1733-4. 2002
  60. ncbi request reprint The compassionate brain: humans detect intensity of pain from another's face
    Miiamaaria V Saarela
    Brain Research Unit, Low Temperature Laboratory, Helsinki University of Technology, Espoo, Finland
    Cereb Cortex 17:230-7. 2007
    ..These findings imply that the intersubjective representation of pain in the human brain is more detailed than has been previously thought...
  61. ncbi request reprint Breakthrough pain in malignant and non-malignant diseases: a review of prevalence, characteristics and mechanisms
    Kristina B Svendsen
    Danish Pain Research Center, University Hospital of Aarhus, Noerrebrogade 44, Building 1A, 8000 Aarhus, Denmark
    Eur J Pain 9:195-206. 2005
    ..It is suggested that sensitization could be the common denominator of BTP in malignant and non-malignant pain...
  62. ncbi request reprint How palliative care of cancer patients is organised between a university hospital and primary care in Finland
    Tiina Tasmuth
    Cancer Society of Finland
    Acta Oncol 45:325-31. 2006
    ..Every third patient reported of poor quality of palliative care in the primary care. Also the physicians reported a need for training in palliative care...
  63. ncbi request reprint Subanesthetic ketamine for cancer pain and scientific rigor in cancer pain trials. A reply to Jackson et al
    Rae Frances Bell
    J Pain Symptom Manage 31:386. 2006
  64. ncbi request reprint Biomarkers for pain
    Eija Kalso
    Pain 107:199-201. 2004
  65. ncbi request reprint Prolactin-releasing peptide affects pain, allodynia and autonomic reflexes through medullary mechanisms
    Maija Liisa Kalliomäki
    Department of Biology, Abo Akademi University, Biocity Artillerigatan 6A, 20520 Turku, SF, Finland
    Neuropharmacology 46:412-24. 2004
    ..The results show that PrRP modulates nociception due to supraspinal rather than spinal action, and that its antinociceptive mechanism differs from that previously characterized for NPFF...
  66. ncbi request reprint Pain- and morphine-associated transcriptional regulation of neuropeptide FF and the G-protein-coupled NPFF2 receptor gene
    Johanna M Nystedt
    Department of Biology, Abo Akademi University, Turku, Finland
    Neurobiol Dis 16:254-62. 2004
    ..Acute, but not chronic, morphine activated the genes supraspinally. The results give further evidence for the involvement of the NPFF system in pain modulation and may provide new therapeutic opportunities for pathologic pain...